scholarly article | Q13442814 |
P356 | DOI | 10.1021/CO300094N |
P953 | full work available online at | https://pubs.acs.org/doi/pdf/10.1021/co300094n |
P698 | PubMed publication ID | 22954105 |
P2093 | author name string | Keith James | |
Paul P. Lange | |||
P2860 | cites work | Small Molecule Library Synthesis Using Segmented Flow | Q31040075 |
Synthesis and analysis of combinatorial libraries performed in an automated micro reactor system | Q33202069 | ||
Fully automated continuous flow synthesis of 4,5-disubstituted oxazoles. | Q33262360 | ||
Fully automated flow-through synthesis of secondary sulfonamides in a binary reactor system | Q33277621 | ||
Construction and validation of an automated flow hydrogenation instrument for application in high-throughput organic chemistry | Q33311558 | ||
High-efficiency aminocarbonylation by introducing CO to a pressurized continuous flow reactor | Q33325032 | ||
Stepwise aromatic nucleophilic substitution in continuous flow. Synthesis of an unsymmetrically substituted 3,5-diamino-benzonitrile library. | Q33781586 | ||
Synthesis of a drug-like focused library of trisubstituted pyrrolidines using integrated flow chemistry and batch methods | Q33884542 | ||
The application of micro reactors for organic synthesis | Q36052130 | ||
Strained Cyclophane Macrocycles: Impact of Progressive Ring Size Reduction on Synthesis and Structure | Q36152470 | ||
Pharmaceutical strategy and innovation: an academics perspective | Q36801630 | ||
Mechanistically diverse copper-, silver-, and gold-catalyzed acyloxy and phosphatyloxy migrations: efficient synthesis of heterocycles via cascade migration/cycloisomerization approach | Q36876714 | ||
Low temperature organocopper-mediated two-component cross coupling/cycloisomerization approach toward N-fused heterocycles | Q37041968 | ||
Application of combinatorial chemistry science on modern drug discovery | Q37065188 | ||
Biaryl-Bridged Macrocyclic Peptides: Conformational Constraint via Carbogenic Fusion of Natural Amino Acid Side Chains | Q44818552 | ||
Efficient access to new chemical space through flow--construction of druglike macrocycles through copper-surface-catalyzed azide-alkyne cycloaddition reactions | Q46092826 | ||
A novel Cu-assisted cycloisomerization of alkynyl imines: efficient synthesis of pyrroles and pyrrole-containing heterocycles | Q49308433 | ||
Ultrasound-assisted click chemistry in continuous flow | Q53405979 | ||
Group efficiency: a guideline for hits-to-leads chemistry | Q53534073 | ||
A guide to drug discovery: The role of the medicinal chemist in drug discovery — then and now | Q56687213 | ||
Optimisation of Conditions forO-Benzyl andN-Benzyloxycarbonyl Protecting Group Removal using an Automated Flow Hydrogenator | Q56952408 | ||
Synthesis and solid state study of pyridine- and pyrimidine-based fragment libraries | Q63350076 | ||
Facile synthesis of substituted thiophenes via Pd/C-mediated sonogashira coupling in water | Q79164694 | ||
General and direct synthesis of 3-aminoindolizines and their analogues via Pd/Cu-catalyzed sequential cross-coupling/cycloisomerization reactions | Q79650284 | ||
Parallel synthesis in an EOF-based micro reactor | Q80940044 | ||
Continuous Flow Coupling and Decarboxylation Reactions Promoted by Copper Tubing | Q82803045 | ||
CuAAC Macrocyclization: High Intramolecular Selectivity through the Use of Copper–Tris(triazole) Ligand Complexes | Q83989827 | ||
Synthesis of 5-Iodo-1,2,3-triazole-Containing Macrocycles Using Copper Flow Reactor Technology | Q84524938 | ||
A multistep continuous-flow system for rapid on-demand synthesis of receptor ligands | Q84774090 | ||
P433 | issue | 10 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | combinatorial chemistry | Q899212 |
P304 | page(s) | 570-578 | |
P577 | publication date | 2012-09-10 | |
P1433 | published in | ACS combinatorial science | Q27723471 |
P1476 | title | Rapid access to compound libraries through flow technology: fully automated synthesis of a 3-aminoindolizine library via orthogonal diversification | |
Rapid Access to Compound Libraries through Flow Technology: Fully Automated Synthesis of a 3-Aminoindolizine Library via Orthogonal Diversification | |||
P478 | volume | 14 |
Q38209736 | Accessing new chemical entities through microfluidic systems |
Q47780833 | Automating drug discovery |
Q60063471 | Continuous Flow Synthesis of Urea-Containing Compound Libraries Based on the Piperidin-4-one Scaffold |
Q28066266 | Current status and future prospects for enabling chemistry technology in the drug discovery process |
Q34910444 | Disubstituted 1-Aryl-4-Aminopiperidine Library Synthesis Using Computational Drug Design and High-Throughput Batch and Flow Technologies |
Q89834926 | Flow Synthesis of Biologically-Relevant Compound Libraries |
Q47686191 | Rapid Vortex Fluidics: Continuous Flow Synthesis of Amides and Local Anesthetic Lidocaine. |
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