Endothelial Kruppel-like factor 4 regulates angiogenesis and the Notch signaling pathway

scientific article

Endothelial Kruppel-like factor 4 regulates angiogenesis and the Notch signaling pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M113.530956
P932PMC publication ID4002108
P698PubMed publication ID24599951
P5875ResearchGate publication ID260559545

P2093author name stringXudong Liao
Anne Hamik
Aaron Proweller
Hongmei Tian
Mohammad A Shatat
Fernando O Recio
Andrew T Hale
Masakazu Ishikawa
Diana L Ramirez-Bergeron
Trent Johnson
Ejike Anih
P2860cites workA protocol for isolation and culture of human umbilical vein endothelial cells.Q61638945
Deficiency in endothelial nitric oxide synthase impairs myocardial angiogenesisQ78396603
An antisense oligonucleotide to the notch ligand jagged enhances fibroblast growth factor-induced angiogenesis in vitroQ24336333
Mammalian Krüppel-Like Factors in Health and DiseasesQ24612560
Klf4 is a transcription factor required for establishing the barrier function of the skinQ28115084
Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cellsQ28512115
Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1Q28589104
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesisQ29614939
Notch signaling is essential for vascular morphogenesis in miceQ29620377
Endothelial Kruppel-like factor 4 protects against atherothrombosis in miceQ30423011
Endothelial Krüppel-like factor 4 modulates pulmonary arterial hypertensionQ33799629
Differential control of Notch1 gene transcription by Klf4 and Sp3 transcription factors in normal versus cancer-derived keratinocytesQ33815952
Kruppel-like factor-4 transcriptionally regulates VE-cadherin expression and endothelial barrier functionQ34132272
Defining the regulation of KLF4 expression and its downstream transcriptional targets in vascular endothelial cellsQ34193616
Targeting Notch signaling pathway to overcome drug resistance for cancer therapyQ34205088
Expression of Kruppel-like factor KLF4 in mouse hair follicle stem cells contributes to cutaneous wound healingQ34321610
Maintenance of somite borders in mice requires the Delta homologue DII1.Q34422203
Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell functionQ34456711
Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell functionQ34458950
The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogeneQ34462232
Angiopoietin-1/Tie2 signal augments basal Notch signal controlling vascular quiescence by inducing delta-like 4 expression through AKT-mediated activation of beta-cateninQ34624256
Krüppel-like factor 4 regulates B cell number and activation-induced B cell proliferationQ34689980
Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signalingQ34811698
Notch signaling in vascular developmentQ35077358
Regulation of vascular morphogenesis by Notch signalingQ36972249
KLF4 gene expression is inhibited by the notch signaling pathway that controls goblet cell differentiation in mouse gastrointestinal tractQ37138765
Angiogenesis: a team effort coordinated by notch.Q37393190
Crosstalk of VEGF and Notch pathways in tumour angiogenesis: therapeutic implicationsQ37410402
Competitive interactions between cells: death, growth, and geographyQ37531604
Dll4-Notch signaling as a therapeutic target in tumor angiogenesisQ37933528
The Notch1-Dll4 signaling pathway regulates mouse postnatal lymphatic developmentQ39519137
Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesisQ40191484
Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesisQ40191493
Krüppel acts as a developmental switch gene that mediates Notch signalling-dependent tip cell differentiation in the excretory organs of DrosophilaQ42099803
Endothelial cells dynamically compete for the tip cell position during angiogenic sproutingQ42876374
Isolation of human umbilical vein endothelial cells (HUVEC).Q43248515
Kruppel-like factor 4 regulates endothelial inflammation.Q55043476
Chronic DLL4 blockade induces vascular neoplasmsQ59082154
P4510describes a project that usesImageJQ1659584
P433issue17
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
angiogenesisQ539568
P1104number of pages13
P304page(s)12016-12028
P577publication date2014-03-05
P1433published inJournal of Biological ChemistryQ867727
P1476titleEndothelial Kruppel-like factor 4 regulates angiogenesis and the Notch signaling pathway
P478volume289

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cites work (P2860)
Q34525997Actions of the protein kinase WNK1 on endothelial cells are differentially mediated by its substrate kinases OSR1 and SPAK.
Q64056424Angiogenic Endothelial Cell Signaling in Cardiac Hypertrophy and Heart Failure
Q41397599Brain vascular pericytes following ischemia have multipotential stem cell activity to differentiate into neural and vascular lineage cells
Q38980848Circulating Endothelial Cells Expressing the Angiogenic Transcription Factor Krüppel-Like Factor 4 are Decreased in Patients with Coronary Artery Disease
Q33626500Differential microRNA expression in human placentas of term intra-uterine growth restriction that regulates target genes mediating angiogenesis and amino acid transport
Q26773015Endothelial Transdifferentiation of Tumor Cells Triggered by the Twist1-Jagged1-KLF4 Axis: Relationship between Cancer Stemness and Angiogenesis
Q35150547Genome-wide analyses identify KLF4 as an important negative regulator in T-cell acute lymphoblastic leukemia through directly inhibiting T-cell associated genes
Q34494208HIV vasculopathy: role of mononuclear cell-associated Krüppel-like factors 2 and 4.
Q55192211Increasing aggressiveness of patient-derived xenograft models of cervix carcinoma during serial transplantation.
Q38958138Induction of GADD34 Regulates the Neurotoxicity of Amyloid β.
Q44019514Inhibition of Notch signaling facilitates the differentiation of human-induced pluripotent stem cells into neural stem cells
Q47162611Inhibition of the H3K9 methyltransferase G9A attenuates oncogenicity and activates the hypoxia signaling pathway
Q35663864KLF4 Promotes Angiogenesis by Activating VEGF Signaling in Human Retinal Microvascular Endothelial Cells
Q30278010KLF4 is a key determinant in the development and progression of cerebral cavernous malformations
Q36106100Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis.
Q39151066Krüppel-like factor 4 (KLF4): What we currently know
Q47676828Krüppel-like factors and vascular wall homeostasis.
Q48247130Markers and Biomarkers of Endothelium: When Something Is Rotten in the State.
Q55021223MiR-212 Attenuates MPP⁺-Induced Neuronal Damage by Targeting KLF4 in SH-SY5Y Cells.
Q34526886MicroRNA-10b regulates epithelial-mesenchymal transition by modulating KLF4/Notch1/E-cadherin in cisplatin-resistant nasopharyngeal carcinoma cells
Q50423780Molecular Regulation of Sprouting Angiogenesis
Q34287855Novel paracrine modulation of Notch-DLL4 signaling by fibulin-3 promotes angiogenesis in high-grade gliomas.
Q46223835ORAI1 Activates Proliferation of Lymphatic Endothelial Cells in Response to Laminar Flow Through Krüppel-Like Factors 2 and 4.
Q38836349Overexpression of miR-18a negatively regulates myocyte enhancer factor 2D to increase the permeability of the blood-tumor barrier via Krüppel-like factor 4-mediated downregulation of zonula occluden-1, claudin-5, and occludin
Q47899533PDGF-BB/KLF4/VEGF Signaling Axis in Pulmonary Artery Endothelial Cell Angiogenesis
Q90117523Regulation of cancer stem cell properties, angiogenesis, and vasculogenic mimicry by miR-450a-5p/SOX2 axis in colorectal cancer
Q38747777Role of the reprogramming factor KLF4 in blood formation
Q38888875Sialyltransferase7A, a Klf4-responsive gene, promotes cardiomyocyte apoptosis during myocardial infarction
Q36109992The cerebral cavernous malformation pathway controls cardiac development via regulation of endocardial MEKK3 signaling and KLF expression.
Q35705474Tongxinluo (TXL), a Traditional Chinese Medicinal Compound, Improves Endothelial Function After Chronic Hypoxia Both In Vivo and In Vitro

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