Gene therapy in autoimmune disease

scientific article

Gene therapy in autoimmune disease is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0952-7915(01)00278-3
P698PubMed publication ID11677089

P2093author name stringFathman CG
Tarner IH
P2860cites workProtection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritisQ24792053
Gene therapy for established murine collagen-induced arthritis by local and systemic adenovirus-mediated delivery of interleukin-4Q24792474
CTLA-4 can function as a negative regulator of T cell activationQ28235866
T cell design for therapy in autoimmune demyelinating diseaseQ33943452
Treatment of murine lupus with cDNA encoding IFN-gammaR/FcQ35126621
Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosisQ36375186
A20 inhibits cytokine-induced apoptosis and nuclear factor kappaB-dependent gene activation in isletsQ36375424
Direct adenovirus-mediated gene transfer of interleukin 1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effectsQ36477567
Antigen presenting cells expressing Fas ligand down-modulate chronic inflammatory disease in Fas ligand-deficient miceQ37175936
IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosionQ37202023
Retroviral gene therapy with an immunoglobulin-antigen fusion construct protects from experimental autoimmune uveitisQ37522009
Dendritic cells genetically engineered to express IL-4 inhibit murine collagen-induced arthritisQ39946625
Antigen-specific T cell-mediated gene therapy in collagen-induced arthritisQ39946646
Adoptive immunotherapy of experimental autoimmune encephalomyelitis via T cell delivery of the IL-12 p40 subunitQ40787807
Degradable polymeric carrier for the delivery of IL-10 plasmid DNA to prevent autoimmune insulitis of NOD miceQ40823580
Intramuscular administration of expression plasmids encoding interferon-gamma receptor/IgG1 or IL-4/IgG1 chimeric proteins protects from autoimmunityQ40831887
Targeting rare populations of murine antigen-specific T lymphocytes by retroviral transduction for potential application in gene therapy for autoimmune diseaseQ40892667
Gene therapy for chronic relapsing experimental allergic encephalomyelitis using cells expressing a novel soluble p75 dimeric TNF receptorQ40897697
Prevention of autoimmune diabetes by intramuscular gene therapy with a nonviral vector encoding an interferon-gamma receptor/IgG1 fusion proteinQ40925888
Reversal of diabetes in mice by implantation of human fibroblasts genetically engineered to release mature human insulinQ40935576
Adenovirus-mediated gene transfer of A20 in murine islets inhibits Fas-induced apoptosisQ43552660
Adenoviral gene therapy with catalase suppresses experimental optic neuritisQ44093665
Mechanisms of tolerance induction by a gene-transferred peptide-IgG fusion protein expressed in B lineage cellsQ45144542
Adeno-associated virus-mediated delivery of IL-4 prevents collagen-induced arthritisQ45739253
Transfection of human pancreatic islets with an anti-apoptotic gene (bcl-2) protects beta-cells from cytokine-induced destructionQ45858530
Th2 T cells expressing transgene PDGF-A serve as vectors for gene therapy in autoimmune demyelinating diseaseQ45861217
Encapsulation in hollow fibres of xenogeneic cells engineered to secrete IL-4 or IL-13 ameliorates murine collagen-induced arthritis (CIA).Q45861247
Prevention of experimental allergic encephalomyelitis by intramuscular gene transfer with cytokine-encoding plasmid vectorsQ45861828
Suppressed severity of collagen-induced arthritis by in vivo transfection of nuclear factor kappaB decoy oligodeoxynucleotides as a gene therapyQ45864343
Engineering mouse T lymphocytes specific to type II collagen by transduction with a chimeric receptor consisting of a single chain Fv and TCR zetaQ45867388
Gene therapy that inhibits nuclear translocation of nuclear factor kappaB results in tumor necrosis factor alpha-induced apoptosis of human synovial fibroblastsQ45867714
Cytokine therapy in immune-mediated demyelinating diseases of the central nervous system: a novel gene therapy approachQ45868690
Soluble complement receptor 1 (CD35) delivered by retrovirally infected syngeneic cells or by naked DNA injection prevents the progression of collagen-induced arthritisQ45870165
Bone marrow-derived cells as carriers of recombinant immunomodulatory cytokine genes to lymphoid organsQ45870540
Remission in models of type 1 diabetes by gene therapy using a single-chain insulin analogueQ45872828
IL-4 adenoviral gene therapy reduces inflammation, proinflammatory cytokines, vascularization, and bony destruction in rat adjuvant-induced arthritisQ45873853
A gene therapy approach for treating T-cell-mediated autoimmune diseasesQ45873983
Redirection of T cell effector function in vivo and enhanced collagen-induced arthritis mediated by an IL-2R beta/IL-4R alpha chimeric cytokine receptor transgeneQ45875347
Adenovirus-mediated gene transfer of CTLA-4Ig fusion protein in the suppression of experimental autoimmune arthritisQ56905891
CTLA4IgG gene delivery prevents autoantibody production and lupus nephritis in MRL/lpr miceQ56906450
Treatment of chronic sialadenitis in a murine model of Sjögren's syndrome by local fasL gene transferQ64379911
Effective treatment of established murine collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express IL-4Q64380123
Viral IL-10 and soluble TNF receptor act synergistically to inhibit collagen-induced arthritis following adenovirus-mediated gene transferQ64381028
Gene therapy for rheumatoid arthritisQ64381800
Antigen-specific T cells transduced with IL-10 ameliorate experimentally induced arthritis without impairing the systemic immune response to the antigenQ73163243
Expression of Fas ligand improves the effect of IL-4 in collagen-induced arthritisQ73281919
P433issue6
P921main subjectautoimmune diseaseQ8084905
gene therapyQ213901
P304page(s)676-682
P577publication date2001-12-01
P1433published inCurrent Opinion in ImmunologyQ15752917
P1476titleGene therapy in autoimmune disease
P478volume13

Reverse relations

cites work (P2860)
Q46620103Adenovirus-mediated gene delivery of interleukin-10, but not transforming growth factor beta, ameliorates the induction of Graves' hyperthyroidism in BALB/c mice
Q45867292Adoptive Cellular Gene Therapy for the Treatment of Experimental Autoimmune Polychondritis Ear Disease
Q35172114Adoptive cellular gene therapy of autoimmune disease
Q35164793Gene transfer as a future therapy for rheumatoid arthritis
Q45863664Localized expression of an anti-TNF single-chain antibody prevents development of collagen-induced arthritis
Q31122835Specific modulation of the anti-DNA autoantibody-nucleic acids interaction by the high affinity RNA aptamer
Q45861637Stem cells engineered to express self-antigen to treat autoimmunity
Q33757547Still waiting for the end. The promise of genomics and proteomics for autoimmune diseases
Q36433286Synovial fibroblasts: key players in rheumatoid arthritis
Q40690904Targeting autoantigen-specific T cells and suppression of autoimmune encephalomyelitis with receptor-modified T lymphocytes
Q34580287Therapeutic applications for hematopoietic stem cell gene transfer
Q46415552Transgene delivery and gelonin cytotoxicity enhanced by photochemical internalization in fibroblast-like synoviocytes (FLS) from rheumatoid arthritis patients

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