MtDNA segregation in heteroplasmic tissues is common in vivo and modulated by haplotype differences and developmental stage

scientific article

MtDNA segregation in heteroplasmic tissues is common in vivo and modulated by haplotype differences and developmental stage is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CELREP.2014.05.020
P932PMC publication ID4570183
P698PubMed publication ID24910436
P5875ResearchGate publication ID262942789

P50authorIain G. JohnstonQ37378314
Andreas FutschikQ56435563
Joanna PoultonQ63363610
Jaroslav PiálekQ64878613
P2093author name stringThomas Rülicke
Claus Vogl
Thomas Kolbe
Nick S Jones
Gottfried Brem
Christian Gülly
Corina Mayrhofer
Dieter Klein
Jana Albrechtová
Joerg Patrick Burgstaller
Mirjam Blattner
Ralf Steinborn
Sonja Sabitzer
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Gimap3 regulates tissue-specific mitochondrial DNA segregationQ28585352
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Mitochondrial genotype segregation in a mouse heteroplasmic lineage produced by embryonic karyoplast transplantationQ33969425
Decrease of 3243 A-->G mtDNA mutation from blood in MELAS syndrome: a longitudinal studyQ34043733
Mitochondrial DNA transmission, replication and inheritance: a journey from the gamete through the embryo and into offspring and embryonic stem cellsQ34104122
Human paternal and maternal demographic histories: insights from high-resolution Y chromosome and mtDNA sequences.Q34239849
Heteroplasmy of mouse mtDNA is genetically unstable and results in altered behavior and cognitionQ34246973
Functional differences between mitochondrial haplogroup T and haplogroup H in HEK293 cybrid cellsQ34540620
Replicative advantage and tissue-specific segregation of RR mitochondrial DNA between C57BL/6 and RR heteroplasmic miceQ34609738
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Nonneutral evolution at the mitochondrial NADH dehydrogenase subunit 3 gene in miceQ35570984
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Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmissionQ36382138
Deletion-mutant mtDNA increases in somatic tissues but decreases in female germ cells with age.Q36416150
Universal heteroplasmy of human mitochondrial DNA.Q36477684
Selection against pathogenic mtDNA mutations in a stem cell population leads to the loss of the 3243A-->G mutation in bloodQ36719116
Mitochondrial DNA genetics and the heteroplasmy conundrum in evolution and disease.Q37258708
Recurrent tissue-specific mtDNA mutations are common in humansQ37288998
Mitochondrial disorders: aetiologies, models systems, and candidate therapiesQ38113603
Hepatocyte growth factor/scatter factor overexpression induces growth, abnormal development, and tumor formation in transgenic mouse liversQ41154099
Differences in reactive oxygen species production explain the phenotypes associated with common mouse mitochondrial DNA variantsQ42834906
Tissue specific distribution of the 3243A->G mtDNA mutation.Q43169874
Pronounced segregation of donor mitochondria introduced by bovine ooplasmic transfer to the female germ-lineQ43231776
Characterisation of postnatal growth of the murine heartQ43780583
Measurement of mitochondrial DNA synthesis in vivo using a stable isotope-mass spectrometric techniqueQ44299850
Extreme nearly neutral evolution in mitochondrial genomes of laboratory mouse strains.Q45348462
The battle to prevent the transmission of mitochondrial DNA disease: is karyoplast transfer the answer?Q45856126
Regulators weigh benefits of 'three-parent' fertilization.Q48616188
Medicine. Mitochondrial replacement, evolution, and the clinic.Q48617540
Neutral mitochondrial heteroplasmy alters physiological function in mice.Q48790844
Quantitative change in mitochondrial DNA content in various mouse tissues during aging.Q48935514
Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA.Q48985238
Nuclear genetic control of mitochondrial DNA segregationQ57042164
Selection of a mtDNA sequence variant in hepatocytes of heteroplasmic mice is not due to differences in respiratory chain function or efficiency of replicationQ57042235
Tissue-specific selection for different mtDNA genotypes in heteroplasmic miceQ57042902
Reactive oxygen species and the segregation of mtDNA sequence variantsQ80220520
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectheteroplasmyQ2581905
P304page(s)2031-2041
P577publication date2014-06-06
P1433published inCell ReportsQ5058165
P1476titleMtDNA segregation in heteroplasmic tissues is common in vivo and modulated by haplotype differences and developmental stage
P478volume7

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