Macromolecular complexes: SMN--the master assembler

scientific article

Macromolecular complexes: SMN--the master assembler is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/S0960-9822(01)00517-6
P698PubMed publication ID11696342

P2093author name stringTerns MP
Terns RM
P2860cites workA novel function for SMN, the spinal muscular atrophy disease gene product, in pre-mRNA splicingQ22008514
The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteinsQ24316085
The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesisQ24316121
Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy proteinQ24600358
A functional interaction between the survival motor neuron complex and RNA polymerase IIQ24674951
SMN tudor domain structure and its interaction with the Sm proteinsQ27629094
Essential role for the tudor domain of SMN in spliceosomal U snRNP assembly: implications for spinal muscular atrophyQ28137718
Characterization of a nuclear 20S complex containing the survival of motor neurons (SMN) protein and a specific subset of spliceosomal Sm proteinsQ28143590
SMN, the product of the spinal muscular atrophy gene, binds preferentially to dimethylarginine-containing protein targetsQ28199238
The survival of motor neurons (SMN) protein interacts with the snoRNP proteins fibrillarin and GAR1Q28213183
Residual Cajal bodies in coilin knockout mice fail to recruit Sm snRNPs and SMN, the spinal muscular atrophy gene productQ28590925
Identification and characterization of a spinal muscular atrophy-determining geneQ29547495
Direct interaction of the spinal muscular atrophy disease protein SMN with the small nucleolar RNA-associated protein fibrillarinQ31003752
Guided tours: from precursor snoRNA to functional snoRNP.Q33680763
Specific sequences of the Sm and Sm-like (Lsm) proteins mediate their interaction with the spinal muscular atrophy disease gene product (SMN).Q33905442
Cajal bodies: the first 100 yearsQ34059715
SMN mutants of spinal muscular atrophy patients are defective in binding to snRNP proteins.Q35641208
A multiprotein complex mediates the ATP-dependent assembly of spliceosomal U snRNPsQ43803910
P433issue21
P407language of work or nameEnglishQ1860
P921main subjectmacromoleculeQ178593
P304page(s)R862-4
P577publication date2001-10-01
P1433published inCurrent BiologyQ1144851
P1476titleMacromolecular complexes: SMN--the master assembler
P478volume11

Reverse relations

cites work (P2860)
Q38304823A nuclear odyssey: fibroblast growth factor-2 (FGF-2) as a regulator of nuclear homeostasis in the nervous system.
Q44611061A proteomic analysis of arginine-methylated protein complexes
Q36323111A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy.
Q48586550Active transport of the survival motor neuron protein and the role of exon-7 in cytoplasmic localization.
Q24535295An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors mSin3A/B
Q34701211Analysis of human protein replacement stable cell lines established using snoMEN-PR vector
Q37733136Antisense Oligonucleotides: Treatment Strategies and Cellular Internalization
Q36768167Biogenesis and intranuclear trafficking of human box C/D and H/ACA RNPs
Q28189028Cajal body proteins SMN and Coilin show differential dynamic behaviour in vivo
Q24540240Cell cycle-regulated trafficking of human telomerase to telomeres
Q36385395Cellular dynamics of small RNAs
Q82029139Chapter 5 Cytopathology of the motor neuron
Q46881366Characterization of a short isoform of human Tgs1 hypermethylase associating with small nucleolar ribonucleoprotein core proteins and produced by limited proteolytic processing
Q24307701Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein
Q58794833Defective Neuromuscular Junction Organization and Postnatal Myogenesis in Mice With Severe Spinal Muscular Atrophy
Q28203025Determinants of the interaction of the spinal muscular atrophy disease protein SMN with the dimethylarginine-modified box H/ACA small nucleolar ribonucleoprotein GAR1
Q37810374Developments in RNA splicing and disease
Q28578502Differential intranuclear localization of fibroblast growth factor-2 isoforms and specific interaction with the survival of motoneuron protein
Q39079803Emerging role of SETDB1 as a therapeutic target
Q28584703Fibrillarin is essential for early development and required for accumulation of an intron-encoded small nucleolar RNA in the mouse
Q42182559Fibroblast growth factor-2(23) binds directly to the survival of motoneuron protein and is associated with small nuclear RNAs.
Q39072801Genome-wide identification of mRNAs associated with the protein SMN whose depletion decreases their axonal localization
Q79106179Genomic structure and expression of the mouse ESET gene encoding an ERG-associated histone methyltransferase with a SET domain
Q27640685High-resolution X-ray and NMR structures of the SMN Tudor domain: conformational variation in the binding site for symmetrically dimethylated arginine residues
Q35567374Identification of a novel cyclic AMP-response element (CRE-II) and the role of CREB-1 in the cAMP-induced expression of the survival motor neuron (SMN) gene
Q37094802Impaired Muscle Mitochondrial Biogenesis and Myogenesis in Spinal Muscular Atrophy.
Q36559321Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle
Q37218543Increased susceptibility of spinal muscular atrophy fibroblasts to camptothecin is p53-independent
Q46464188Increased susceptibility of spinal muscular atrophy fibroblasts to camptothecin-induced cell death
Q50282492Inherited motor neuron disease in domestic cats: a model of spinal muscular atrophy
Q35567371Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding.
Q36142393Low levels of Survival Motor Neuron protein are sufficient for normal muscle function in the SMNΔ7 mouse model of SMA.
Q27934771Naf1p, an essential nucleoplasmic factor specifically required for accumulation of box H/ACA small nucleolar RNPs
Q39521045Neuronal SMN expression corrects spinal muscular atrophy in severe SMA mice while muscle-specific SMN expression has no phenotypic effect
Q22121992Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs
Q36768163Noncoding RNAs of the H/ACA family
Q36827345RNA transport and localized protein synthesis in neurological disorders and neural repair
Q34762623Repair of pre-mRNA splicing: prospects for a therapy for spinal muscular atrophy.
Q41694012SECIS-binding protein 2 interacts with the SMN complex and the methylosome for selenoprotein mRNP assembly and translation
Q24676334SMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin beta
Q34546169Small nucleolar RNAs: versatile trans-acting molecules of ancient evolutionary origin.
Q33914362Specific splicing defects in S. pombe carrying a degron allele of the Survival of Motor Neuron gene
Q35340133Spinal muscular atrophy: journeying from bench to bedside
Q33785933Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?
Q38629976Spliceosomal small nuclear ribonucleoprotein particles repeatedly cycle through Cajal bodies
Q35563254Splicing changes in SMA mouse motoneurons and SMN-depleted neuroblastoma cells: evidence for involvement of splicing regulatory proteins
Q37263631Structure of the insect oocyte nucleus with special reference to interchromatin granule clusters and cajal bodies.
Q34796882TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules
Q34785598Telomerase RNA Accumulates in Cajal Bodies in Human Cancer Cells
Q41967731Telomerase RNA biogenesis involves sequential binding by Sm and Lsm complexes
Q36854864Telomerase reverse transcriptase is required for the localization of telomerase RNA to cajal bodies and telomeres in human cancer cells
Q33951245Telomerase trafficking and assembly in Xenopus oocytes
Q36436723The Cajal body: a meeting place for spliceosomal snRNPs in the nuclear maze
Q26749166The biology of DHX9 and its potential as a therapeutic target
Q24306551The exonuclease ISG20 mainly localizes in the nucleolus and the Cajal (Coiled) bodies and is associated with nuclear SMN protein-containing complexes
Q35038202The many facets of H/ACA ribonucleoproteins
Q34060945The product of the survival of motor neuron (SMN) gene is a human telomerase-associated protein
Q54560146The spinal muscular atrophy disease protein SMN is linked to the Rho-kinase pathway via profilin.
Q80863125Unaffected patients with a homozygous absence of the SMN1 gene

Search more.