| scholarly article | Q13442814 |
| P356 | DOI | 10.1172/JCI8678 |
| P953 | full work available at URL | https://www.jci.org/articles/view/8678/pdf |
| P932 | PMC publication ID | 300850 |
| P698 | PubMed publication ID | 10841514 |
| P8299 | Semantic Scholar corpus ID | 1129225 |
| P4011 | Semantic Scholar paper ID | 63f45f26413315288d32c4a6bc50aac7d8a32858 |
| P50 | author | Klaus-Peter Lesch | Q6419831 |
| P2093 | author name string | L Lanfumey | |
| M Hamon | |||
| S Eddahibi | |||
| N Hanoun | |||
| B Raffestin | |||
| S Adnot | |||
| P2860 | cites work | Protein measurement with the Folin phenol reagent | Q20900776 |
| Valvular heart disease associated with fenfluramine-phentermine | Q28247282 | ||
| Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha | Q28508120 | ||
| Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4-methylenedioxymethamphetamine ("Ecstasy") in serotonin transporter-deficient mice | Q28510046 | ||
| Appetite-suppressant drugs and the risk of primary pulmonary hypertension. International Primary Pulmonary Hypertension Study Group | Q34062887 | ||
| A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter | Q36365615 | ||
| Hypoxia regulates expression of the endothelin-1 gene through a proximal hypoxia-inducible factor-1 binding site on the antisense strand | Q38337607 | ||
| Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia | Q40339677 | ||
| Serotonin stimulates mitogen-activated protein kinase activity through the formation of superoxide anion | Q40935981 | ||
| Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia. | Q41091104 | ||
| A new role for an old molecule: serotonin as a mitogen | Q41491984 | ||
| Rat pulmonary circulation after chronic hypoxia: hemodynamic and structural features | Q41600973 | ||
| Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5' enhancer | Q42481577 | ||
| The pulmonary hypertensive fawn-hooded rat has a normal serotonin transporter coding sequence. | Q47708585 | ||
| Gene structure and 5'-flanking regulatory region of the murine serotonin transporter | Q48053229 | ||
| Dual effect of serotonin on growth of bovine pulmonary artery smooth muscle cells in culture | Q67915539 | ||
| Alterations of central serotonin and dopamine turnover in rats treated with ipsapirone and other 5-hydroxytryptamine1A agonists with potential anxiolytic properties | Q69034713 | ||
| Serotonin uptake and configurational change of bovine pulmonary artery smooth muscle cells in culture | Q69482149 | ||
| Hereditary defect in platelet function in rats | Q70420391 | ||
| Reduced serotonin uptake by spontaneously hypertensive rat platelets | Q71049201 | ||
| Carcinoid heart disease. Correlation of high serotonin levels with valvular abnormalities detected by cardiac catheterization and echocardiography | Q71974455 | ||
| Association of Tyr phosphorylation of GTPase-activating protein with mitogenic action of serotonin | Q73085894 | ||
| Treatment with 5-HT potentiates development of pulmonary hypertension in chronically hypoxic rats | Q73191342 | ||
| Induction of serotonin transporter by hypoxia in pulmonary vascular smooth muscle cells. Relationship with the mitogenic action of serotonin | Q74452830 | ||
| Effect of dexfenfluramine treatment in rats exposed to acute and chronic hypoxia | Q74489965 | ||
| Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia | Q95793841 | ||
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | hypoxia | Q105688 |
| pulmonary hypertension | Q1128595 | ||
| P304 | page(s) | 1555-1562 | |
| P577 | publication date | 2000-06-01 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene | |
| P478 | volume | 105 |
| Q36515926 | 4,4'-Methylenedianiline Alters Serotonergic Transport in a Novel, Sex-Specific Model of Pulmonary Arterial Hypertension in Rats. |
| Q44264971 | 5-Hydroxytryptamine and platelets: uptake and aggregation in hypoxic pulmonary hypertensive rats |
| Q50894828 | 5-Hydroxytryptamine levels in the pulmonary arterioles of broilers with induced pulmonary hypertension and its relationship to pulmonary vascular remodelling. |
| Q34035781 | 5-hydroxytryptamine and the pulmonary circulation: receptors, transporters and relevance to pulmonary arterial hypertension |
| Q28513703 | A critical role for the protein apoptosis repressor with caspase recruitment domain in hypoxia-induced pulmonary hypertension |
| Q38078369 | A process-based review of mouse models of pulmonary hypertension |
| Q34433942 | A role for the serotonin transporter in hypoxia-induced pulmonary hypertension |
| Q44342709 | Activation of GATA-4 by serotonin in pulmonary artery smooth muscle cells |
| Q44705861 | Advancing therapy for pulmonary arterial hypertension: can animal models help? |
| Q33862778 | Altered gene expression in pulmonary tissue of tryptophan hydroxylase-1 knockout mice: implications for pulmonary arterial hypertension |
| Q24799173 | Anorexigen-induced pulmonary hypertension and the serotonin (5-HT) hypothesis: lessons for the future in pathogenesis |
| Q38105550 | Anticipated classes of new medications and molecular targets for pulmonary arterial hypertension |
| Q33973613 | Association between serotonin transporter gene polymorphism and chronic fatigue syndrome |
| Q43249309 | Association study of serotonin transporter gene polymorphisms and ventricular septal defects related possible pulmonary arterial hypertension in Chinese population |
| Q44516763 | Associations between endothelial nitric oxide synthase A/B, angiotensin converting enzyme I/D and serotonin transporter L/S gene polymorphisms with pulmonary hypertension in COPD patients |
| Q44138098 | Biodistribution study of [(123)I] ADAM in mice: correlation with whole body autoradiography |
| Q33661117 | Cell signaling by protein carbonylation and decarbonylation |
| Q37465320 | Cellular and molecular basis of pulmonary arterial hypertension |
| Q37353551 | Cyclooxygenase-2 inhibition and hypoxia-induced pulmonary hypertension: effects on pulmonary vascular remodeling and contractility |
| Q54595222 | Cyclosporin A inhibits hypoxia-induced pulmonary hypertension and right ventricle hypertrophy. |
| Q94603100 | Cytochrome P450 Epoxygenase-Dependent Activation of TRPV4 Channel Participates in Enhanced Serotonin-Induced Pulmonary Vasoconstriction in Chronic Hypoxic Pulmonary Hypertension |
| Q27005594 | DNA Damage and Pulmonary Hypertension |
| Q50124360 | DRUG INDUCED PULMONARY ARTERIAL HYPERTENSION: A PRIMER FOR CLINICIANS AND SCIENTISTS. |
| Q34439111 | Deficiency of actinin-associated LIM protein alters regional right ventricular function and hypertrophic remodeling |
| Q24647096 | Deficiency of the NHE1 gene prevents hypoxia-induced pulmonary hypertension and vascular remodeling |
| Q44180844 | Dexfenfluramine protects against pulmonary hypertension in rats |
| Q43244103 | Differential expression of vasoactive mediators in microparticle-challenged lungs of chickens that differ in susceptibility to pulmonary arterial hypertension |
| Q36977139 | Elastin insufficiency predisposes to elevated pulmonary circulatory pressures through changes in elastic artery structure |
| Q41968228 | Elevated transglutaminase 2 activity is associated with hypoxia-induced experimental pulmonary hypertension in mice |
| Q36821361 | Emerging therapies for pulmonary arterial hypertension |
| Q37209074 | Endothelial cell dysfunction and cross talk between endothelium and smooth muscle cells in pulmonary arterial hypertension. |
| Q51013095 | Enhanced brain stem 5HT₂A receptor function under neonatal hypoxic insult: role of glucose, oxygen, and epinephrine resuscitation. |
| Q35856963 | Enhanced p122RhoGAP/DLC-1 Expression Can Be a Cause of Coronary Spasm |
| Q38112056 | Experimental and transgenic models of pulmonary hypertension. |
| Q44799604 | Extracellular superoxide enhances 5-HT-induced murine pulmonary artery vasoconstriction |
| Q90230119 | Extreme enhancement or depletion of serotonin transporter function and serotonin availability in autism spectrum disorder |
| Q28203160 | Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension |
| Q34653768 | Functions of serotonin in hypoxic pulmonary vascular remodeling |
| Q36943648 | Future perspectives for the treatment of pulmonary arterial hypertension |
| Q87845023 | GPCRs in pulmonary arterial hypertension: tipping the balance |
| Q37133789 | Gender, sex hormones and pulmonary hypertension. |
| Q33442097 | Gene expression in lungs of mice lacking the 5-hydroxytryptamine transporter gene |
| Q36142458 | Gene therapy by targeted adenovirus-mediated knockdown of pulmonary endothelial Tph1 attenuates hypoxia-induced pulmonary hypertension |
| Q38110499 | Genetic and environmental influences on gas exchange |
| Q28388821 | Genetically manipulated mouse models of lung disease: potential and pitfalls |
| Q36752306 | Genetics and mediators in pulmonary arterial hypertension |
| Q37452405 | Genomics of pulmonary arterial hypertension: implications for therapy |
| Q44275998 | Granulocyte colony-stimulating factor enhances alpha-naphthylthiourea-induced pulmonary hypertension |
| Q39752665 | Heterozygous deficiency of hypoxia-inducible factor-2alpha protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia |
| Q30485725 | How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems. |
| Q36577620 | How valid are animal models to evaluate treatments for pulmonary hypertension? |
| Q37015304 | Hypoxia and chronic lung disease. |
| Q40735741 | Hypoxia-induced pulmonary vascular remodeling: a model for what human disease? |
| Q64104814 | Hypoxia-inducible factor-1 α deletion in myeloid lineage attenuates hypoxia-induced pulmonary hypertension |
| Q57099542 | Hypoxic pulmonary vasoconstriction |
| Q34913082 | Idiopathic pulmonary arterial hypertension: an avian model for plexogenic arteriopathy and serotonergic vasoconstriction |
| Q26851508 | Immune and inflammatory mechanisms in pulmonary arterial hypertension |
| Q38111730 | Inflammatory mechanisms in the pathogenesis of pulmonary arterial hypertension |
| Q48439804 | Inhibition of gut- and lung-derived serotonin attenuates pulmonary hypertension in mice |
| Q40006101 | Interactions between integrin alphaIIbbeta3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans |
| Q37787547 | Key role of the RhoA/Rho kinase system in pulmonary hypertension |
| Q33793407 | Key role of the endothelial TGF-β/ALK1/endoglin signaling pathway in humans and rodents pulmonary hypertension |
| Q28361811 | Linking a serotonin transporter polymorphism to vascular smooth muscle proliferation in patients with primary pulmonary hypertension |
| Q36477935 | Mediators and modulators of pulmonary arterial hypertension |
| Q37030844 | Medical therapy for pulmonary arterial hypertension |
| Q24634317 | Molecular pathogenesis of pulmonary arterial hypertension |
| Q36736065 | Molecular pathogenesis of pulmonary arterial hypertension |
| Q36808706 | New insights on receptor-dependent and monoamine oxidase-dependent effects of serotonin in the heart. |
| Q37724192 | New therapies for pulmonary arterial hypertension: an update on current bench to bedside translation |
| Q36964956 | Novel interactions between the 5-HT transporter, 5-HT1B receptors and Rho kinase in vivo and in pulmonary fibroblasts |
| Q38612061 | Novel investigational therapies for treating pulmonary arterial hypertension |
| Q35090255 | Ontogeny and regulation of the serotonin transporter: providing insights into human disorders |
| Q79869502 | Oxygen-dependent regulation of pulmonary circulation |
| Q27325578 | Partially Defective Store Operated Calcium Entry and Hem(ITAM) Signaling in Platelets of Serotonin Transporter Deficient Mice |
| Q56388717 | Pathology of pulmonary hypertension |
| Q44608863 | Polymorphism of the Serotonin Transporter Gene and Pulmonary Hypertension in Chronic Obstructive Pulmonary Disease |
| Q28576329 | Potentiation of 5-hydroxytryptamine (5-HT) responses by a 5-HT uptake inhibitor in pulmonary and systemic vessels: effects of exposing rats to hypoxia |
| Q42374304 | Pregnancy, depression, antidepressants and breast-feeding. |
| Q73370839 | Primary pulmonary hypertension |
| Q28584165 | Proliferation and signaling in fibroblasts: role of 5-hydroxytryptamine2A receptor and transporter |
| Q43862670 | Prostacyclin analogs as the brakes for pulmonary artery smooth muscle cell proliferation: is it sufficient to treat severe pulmonary hypertension? |
| Q33302400 | Proteomics of transformed lymphocytes from a family with familial pulmonary arterial hypertension |
| Q38155079 | Pulmonary arterial hypertension: challenges in translational research and a vision for change |
| Q37184405 | Pulmonary hypertension: therapeutic targets within the serotonin system. |
| Q34466439 | Pulmonary vascular remodeling: a target for therapeutic intervention in pulmonary hypertension |
| Q43954391 | Pulmonary vasoconstriction by serotonin is inhibited by S-nitrosoglutathione |
| Q37532988 | Reactive oxygen species in pulmonary vascular remodeling |
| Q37586828 | RhoA/Rho-kinase signaling: a therapeutic target in pulmonary hypertension |
| Q38177356 | Role of the serotonin transporter in pulmonary arterial hypertension. |
| Q36544945 | Screening the receptorome reveals molecular targets responsible for drug-induced side effects: focus on 'fen-phen'. |
| Q49975788 | Serotonin 2A receptor inhibition protects against the development of pulmonary hypertension and pulmonary vascular remodeling in neonatal mice |
| Q35919662 | Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension |
| Q35695503 | Serotonin induces pulmonary artery smooth muscle cell migration |
| Q34720232 | Serotonin transporter interacts with the PDGFβ receptor in PDGF-BB-induced signaling and mitogenesis in pulmonary artery smooth muscle cells |
| Q45019387 | Serotonin transporter is not required for the development of severe pulmonary hypertension in the Sugen hypoxia rat model |
| Q28361826 | Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension |
| Q37144447 | Serotonin transporter polymorphisms in familial and idiopathic pulmonary arterial hypertension |
| Q37101028 | Serotonin-induced growth of pulmonary artery smooth muscle requires activation of phosphatidylinositol 3-kinase/serine-threonine protein kinase B/mammalian target of rapamycin/p70 ribosomal S6 kinase 1 |
| Q36951874 | Serotonin-mediated protein carbonylation in the right heart |
| Q34777881 | Serotonin: a review |
| Q36045577 | Serotonylated fibronectin is elevated in pulmonary hypertension |
| Q42107478 | Simvastatin mitigates functional and structural impairment of lung and right ventricle in a rat model of cigarette smoke-induced COPD. |
| Q38112038 | Smooth muscle cell hypertrophy, proliferation, migration and apoptosis in pulmonary hypertension |
| Q52877853 | Structural and functional prevention of hypoxia-induced pulmonary hypertension by individualized exercise training in mice. |
| Q37234560 | TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension |
| Q34739040 | Targeting the murine serotonin transporter: insights into human neurobiology. |
| Q37681599 | The Role of Serotonin Transporter in Human Lung Development and in Neonatal Lung Disorders. |
| Q42121099 | The angiopietin-1-Tie2 pathway prevents rather than promotes pulmonary arterial hypertension in transgenic mice |
| Q36860205 | The effects of maternal depression and maternal selective serotonin reuptake inhibitor exposure on offspring |
| Q38102660 | The influence of gender on the development of pulmonary arterial hypertension. |
| Q34394951 | The pathobiology of pulmonary hypertension. Endothelium |
| Q35117079 | The role of 5-HT on the cardiovascular and renal systems and the clinical potential of 5-HT modulation |
| Q55394065 | The serotonin hypothesis in pulmonary hypertension revisited: targets for novel therapies (2017 Grover Conference Series). |
| Q51526684 | The serotonin transporter, gender, and 17β oestradiol in the development of pulmonary arterial hypertension. |
| Q58274173 | Transgenic Mice Overexpressing the 5-Hydroxytryptamine Transporter Gene in Smooth Muscle Develop Pulmonary Hypertension |
| Q27027862 | Transglutaminase 2-mediated serotonylation in pulmonary hypertension |
| Q36411210 | Use of selective serotonin reuptake inhibitors and outcomes in pulmonary arterial hypertension |
| Q36815987 | Vasoactive peptides in cardiovascular (patho)physiology. |
| Q38434699 | What Gene Mutations Affect Serotonin in Mice? |
| Q80237439 | [Animal models of pulmonary arterial hypertension] |
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