Novel mechanism for gonadotropin-releasing hormone neuronal migration involving Gas6/Ark signaling to p38 mitogen-activated protein kinase

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Novel mechanism for gonadotropin-releasing hormone neuronal migration involving Gas6/Ark signaling to p38 mitogen-activated protein kinase is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.22.2.599-613.2002
P932PMC publication ID139735
P698PubMed publication ID11756555
P5875ResearchGate publication ID11600338

P2093author name stringEric R Kandel
Mei Xu
Daniel A Linseman
Kim A Heidenreich
Hiroshi Udo
Brian Varnum
Jerome B Schaack
Margaret E Wierman
Melissa P Allen
P2860cites workAsef, a link between the tumor suppressor APC and G-protein signalingQ24290104
Initial characterization of anosmin-1, a putative extracellular matrix protein synthesized by definite neuronal cell populations in the central nervous systemQ24310149
axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinaseQ24310364
A gene deleted in Kallmann's syndrome shares homology with neural cell adhesion and axonal path-finding moleculesQ24311797
Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6Q24313270
Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3Q24532043
MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathwayQ24650627
A simplified system for generating recombinant adenovirusesQ24682328
Rho GTPases and the actin cytoskeletonQ27860579
The small GTP-binding protein rac regulates growth factor-induced membrane rufflingQ27861063
The candidate gene for the X-linked Kallmann syndrome encodes a protein related to adhesion moleculesQ28118633
Apoptosis signal-regulating kinase 1 (ASK1) induces neuronal differentiation and survival of PC12 cellsQ28139737
A novel putative tyrosine kinase receptor with oncogenic potentialQ28273122
Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonineQ28287650
Growth arrest-specific gene 6 (Gas6)/adhesion related kinase (Ark) signaling promotes gonadotropin-releasing hormone neuronal survival via extracellular signal-regulated kinase (ERK) and AktQ28297002
Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinasesQ28298018
Regulation of mitogen-activated protein kinases in cardiac myocytes through the small G protein Rac1Q28346098
Tyro-3 family receptors are essential regulators of mammalian spermatogenesisQ28585555
Signaling through the ARK tyrosine kinase receptor protects from apoptosis in the absence of growth stimulationQ28589590
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosisQ29547567
Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPasesQ29618793
Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in DrosophilaQ30168983
Inhibitors of p38 MAP kinase increase the survival of transplanted dopamine neuronsQ31873495
Expression of the receptor protein-tyrosine kinases Tyro-3, Axl, and mer in the developing rat central nervous systemQ33914948
Evidence that cells expressing luteinizing hormone-releasing hormone mRNA in the mouse are derived from progenitor cells in the olfactory placodeQ34314255
Identification of Gas6 as a growth factor for human Schwann cellsQ34375643
Gas6, the ligand of Axl tyrosine kinase receptor, has mitogenic and survival activities for serum starved NIH3T3 fibroblastsQ34380670
Origin of luteinizing hormone-releasing hormone neuronsQ34497621
Luteinizing hormone-releasing hormone (LHRH)-expressing cells do not migrate normally in an inherited hypogonadal (Kallmann) syndromeQ34514073
Efficient selection of recombinant adenoviruses by vectors that express beta-galactosidase.Q35840357
Differential activation of the Ras/extracellular-signal-regulated protein kinase pathway is responsible for the biological consequences induced by the Axl receptor tyrosine kinaseQ36556713
The receptor tyrosine kinase ARK mediates cell aggregation by homophilic bindingQ36566375
Intrahypothalamic injection of a cell line secreting gonadotropin-releasing hormone results in cellular differentiation and reversal of hypogonadism in mutant miceQ37292417
Migratory arrest of gonadotropin-releasing hormone neurons in transgenic miceQ37486316
Intrinsic pulsatile secretory activity of immortalized luteinizing hormone-releasing hormone-secreting neuronsQ37600302
Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motilityQ39714519
Myocyte enhancer factors-2B and -2C are required for adhesion related kinase repression of neuronal gonadotropin releasing hormone gene expressionQ40854112
Identification of novel factors that regulate GnRH gene expression and neuronal migrationQ41021561
Modulation of actin dynamics during stress and physiological stimulation by a signaling pathway involving p38 MAP kinase and heat-shock protein 27.Q41037943
GAS6 mediates adhesion of cells expressing the receptor tyrosine kinase Axl.Q41091650
An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous systemQ41183910
Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1Q41283042
New insights into the control of cell growth; the role of the AxI familyQ41523439
Immortalization of hypothalamic GnRH neurons by genetically targeted tumorigenesisQ41729068
The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.Q42125827
Ontogeny of gonadotropin-releasing hormone-containing neurons in early fetal development of rhesus macaquesQ42477729
Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cellsQ42539781
A putative receptor tyrosine kinase with unique structural topologyQ42621246
Gas6-mediated survival in NIH3T3 cells activates stress signalling cascade and is independent of Ras.Q42812461
Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolismQ44509062
The 27-kDa heat shock protein facilitates basic fibroblast growth factor release from endothelial cellsQ46042183
Role of a new Rho family member in cell migration and axon guidance in C. elegansQ46184903
Dosage-sensitive, reciprocal genetic interactions between the Abl tyrosine kinase and the putative GEF trio reveal trio's role in axon pathfindingQ47070286
The guanine nucleotide exchange factor trio mediates axonal development in the Drosophila embryoQ47071043
Gas6, a ligand for the receptor protein-tyrosine kinase Tyro-3, is widely expressed in the central nervous systemQ48311967
An alternative gonadotropin-releasing hormone (GnRH) RNA splicing product found in cultured GnRH neurons and mouse hypothalamusQ48707929
p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cellsQ50336697
Expression of Tiam-1 in the developing brain suggests a role for the Tiam-1-Rac signaling pathway in cell migration and neurite outgrowth.Q52197312
A Role for p38MAPK/HSP27 Pathway in Smooth Muscle Cell MigrationQ54964221
A Subset of Peripherin Positive Olfactory Axons Delineates the Luteinizing Hormone Releasing Hormone Neuronal Migratory Pathway in Developing MouseQ60444175
Human HSP27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase IIQ67728245
The migration of luteinizing hormone-releasing hormone neurons in the developing rat is associated with a transient, caudal projection of the vomeronasal nerveQ71038645
Cyclic AMP-induced neuronal differentiation via activation of p38 mitogen-activated protein kinaseQ73080993
Role of p38 mitogen-activated protein kinase in a murine model of pulmonary inflammationQ73407117
Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinaseQ73575389
Immortalized luteinizing hormone-releasing hormone neurons show a different migratory activity in vitroQ73832184
Phosphatidylinositol 3-kinases regulate ERK and p38 MAP kinases in canine colonic smooth muscleQ74061131
GAS6 induces Axl-mediated chemotaxis of vascular smooth muscle cellsQ74326161
Gonadotropin-releasing hormone deficiency in the human (idiopathic hypogonadotropic hypogonadism and Kallmann's syndrome): pathophysiological and genetic considerationsQ77481731
Platelet-derived growth factor activates p38 mitogen-activated protein kinase through a Ras-dependent pathway that is important for actin reorganization and cell migrationQ77726417
C-reactive protein inhibits chemotactic peptide-induced p38 mitogen-activated protein kinase activity and human neutrophil movementQ77863770
Specific activation of the p38 mitogen-activated protein kinase signaling pathway and induction of neurite outgrowth in PC12 cells by bone morphogenetic protein-2Q78208149
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)599-613
P577publication date2002-01-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleNovel mechanism for gonadotropin-releasing hormone neuronal migration involving Gas6/Ark signaling to p38 mitogen-activated protein kinase
P478volume22

Reverse relations

cites work (P2860)
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