Echinacea species (Echinacea angustifolia (DC.) Hell., Echinacea pallida (Nutt.) Nutt.,Echinacea purpurea (L.) Moench): a review of their chemistry, pharmacology and clinical properties

scientific article

Echinacea species (Echinacea angustifolia (DC.) Hell., Echinacea pallida (Nutt.) Nutt.,Echinacea purpurea (L.) Moench): a review of their chemistry, pharmacology and clinical properties is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1211/0022357056127
P698PubMed publication ID16102249
P5875ResearchGate publication ID7658800

P50authorJoanne BarnesQ44019308
P2093author name stringSimon Gibbons
J David Phillipson
Linda A Anderson
P2860cites workEvidence from two classic irritation tests for an anti-inflammatory action of a natural extract, Echinacina B.Q54424483
Echinaforce and other Echinacea fresh plant preparations in the treatment of the common cold. A randomized, placebo controlled, double-blind clinical trial.Q55033009
Patuletin-3-O-Rutinoside from the Aerial Parts of Echinacea angustifoliaQ56777160
Echinacoside and caffeoyl conjugates protect collagen from free radical-induced degradation: a potential use of Echinacea extracts in the prevention of skin photodamageQ59195777
Gas chromatography-mass spectral analysis of roots ofEchinacea species and classification by multivariate data analysisQ104374896
Effects of Root Drying Temperature and Moisture Content on the Levels of Active Ingredients in Echinacea RootsQ104386017
Standardization ofEchinacea purpureaExpressed Juice with Reference to Cichoric Acid and AlkamidesQ104388827
Bioactivity of alkamides isolated from Echinacea purpurea (L.) MoenchQ28193132
Oral administration of freshly expressed juice of Echinacea purpurea herbs fail to stimulate the nonspecific immune response in healthy young men: results of a double-blind, placebo-controlled crossover studyQ28198183
The effect of echinacea (Echinacea purpurea root) on cytochrome P450 activity in vivoQ28241382
Echinacea purpurea therapy for the treatment of the common cold: a randomized, double-blind, placebo-controlled clinical trialQ28266919
Medicinal properties of Echinacea: a critical reviewQ33845969
Efficacy and safety of echinacea in treating upper respiratory tract infections in children: a randomized controlled trial.Q33974381
Efficacy of a standardized echinacea preparation (Echinilin) for the treatment of the common cold: a randomized, double-blind, placebo-controlled trialQ33975378
Ineffectiveness of echinacea for prevention of experimental rhinovirus coldsQ33979856
Immunomodulation with echinacea - a systematic review of controlled clinical trialsQ34034578
Does the extract of the plant Echinacea purpurea influence the clinical course of recurrent genital herpes?Q34170026
Echinacea alkylamides modulate TNF-alpha gene expression via cannabinoid receptor CB2 and multiple signal transduction pathwaysQ34369966
Alkamide levels in Echinacea purpurea: a rapid analytical method revealing differences among roots, rhizomes, stems, leaves and flowersQ34606089
TLC and HPLC Analysis of Alkamides in Echinacea Drugs1,2.Q34607522
Acute disseminated encephalomyelitis after parenteral therapy with herbal extracts: a report of two casesQ35459554
Different standards for reporting ADRs to herbal remedies and conventional OTC medicines: face-to-face interviews with 515 users of herbal remedies.Q35802401
Benefit-risk assessment of the squeezed sap of the purple coneflower (Echinacea purpurea) for long-term oral immunostimulation.Q38063601
Acute drought stress and plant age effects on alkamide and phenolic acid content in purple coneflower rootsQ39031592
Virus-inhibition by echinacea purpurea (author's transl)Q40137166
Effectiveness of an herbal preparation containing echinacea, propolis, and vitamin C in preventing respiratory tract infections in children: a randomized, double-blind, placebo-controlled, multicenter studyQ40539304
The efficacy of echinacea compound herbal tea preparation on the severity and duration of upper respiratory and flu symptoms: a randomized, double-blind placebo-controlled studyQ40615497
Echinacea root extracts for the prevention of upper respiratory tract infections: a double-blind, placebo-controlled randomized trialQ40835053
Results of five randomized studies on the immunomodulatory activity of preparations of EchinaceaQ40979348
An alternative medicine study of herbal effects on the penetration of zona-free hamster oocytes and the integrity of sperm deoxyribonucleic acidQ41610965
Inhibition of human sperm motility by specific herbs used in alternative medicineQ41613881
Antiviral activity of Viracea against acyclovir susceptible and acyclovir resistant strains of herpes simplex virusQ42539361
Macrophage activation by the polysaccharide arabinogalactan isolated from plant cell cultures of Echinacea purpureaQ43538128
Antiviral activity of characterized extracts from echinacea spp. (Heliantheae: Asteraceae) against herpes simplex virus (HSV-I).Q43605056
Comparison of chemical components and antioxidants capacity of different Echinacea speciesQ43655086
Echinacea purpurea and melatonin augment natural-killer cells in leukemic mice and prolong life spanQ43663606
Absorption of dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides after oral application of Echinacea purpurea tinctureQ43824115
Anti-inflammatory and cicatrizing activity of Echinacea pallida Nutt. root extract.Q43860528
Alkylamides of Echinacea purpurea stimulate alveolar macrophage function in normal ratsQ43866771
Polysaccharides isolated from Echinacea purpurea herba cell cultures to counteract undesired effects of chemotherapy--a pilot studyQ43947551
Transport of alkamides from Echinacea species through Caco-2 monolayersQ44023275
Critical hypokalemic renal tubular acidosis due to Sj�gren's syndrome: association with the purported immune stimulant echinaceaQ44436655
The American coneflower: a prophylactic role involving nonspecific immunityQ44628724
Permeability studies of alkylamides and caffeic acid conjugates from echinacea using a Caco-2 cell monolayer model.Q44746150
Can an herbal preparation of echinacea, propolis, and vitamin C reduce respiratory illnesses in children?Q44781922
In vivo assessment of botanical supplementation on human cytochrome P450 phenotypes: Citrus aurantium, Echinacea purpurea, milk thistle, and saw palmetto.Q45146006
Nonspecific immunostimulation with low doses of cyclophosphamide (LDCY), thymostimulin, and Echinacea purpurea extracts (echinacin) in patients with far advanced colorectal cancers: preliminary resultsQ45800757
Comparative controlled study of Andrographis paniculata fixed combination, Kan Jang and an Echinacea preparation as adjuvant, in the treatment of uncomplicated respiratory disease in childrenQ48025565
Polysaccharides isolated from plant cell cultures of Echinacea purpurea enhance the resistance of immunosuppressed mice against systemic infections with Candida albicans and Listeria monocytogenes.Q54236242
Application of purified polysaccharides from cell cultures of the plant Echinacea purpurea to mice mediates protection against systemic infections with Listeria monocytogenes and Candida albicans.Q54304780
P433issue8
P921main subjectpharmacologyQ128406
Echinacea purpureaQ272661
Echinacea angustifoliaQ1062627
Echinacea pallidaQ1813728
P304page(s)929-954
P577publication date2005-08-01
P1433published inJournal of Pharmacy and PharmacologyQ10532762
P1476titleEchinacea species (Echinacea angustifolia (DC.) Hell., Echinacea pallida (Nutt.) Nutt.,Echinacea purpurea (L.) Moench): a review of their chemistry, pharmacology and clinical properties
P478volume57

Reverse relations

cites work (P2860)
Q41234878A C-banded karyotype of mitotic chromosomes in diploid purple coneflower (Echinacea purpurea L.).
Q92600630A strategy for test article selection and phytochemical characterization of Echinacea purpurea extract for safety testing
Q36631506Alcohol extracts of Echinacea inhibit production of nitric oxide and tumor necrosis factor-alpha by macrophages in vitro
Q34278613Alkamid database: Chemistry, occurrence and functionality of plant N-alkylamides.
Q35971775Alkamide stability in Echinacea purpurea extracts with and without phenolic acids in dry films and in solution
Q28302804Alkylamides from Echinacea are a new class of cannabinomimetics. Cannabinoid type 2 receptor-dependent and -independent immunomodulatory effects
Q90270091An Ultrasensitive Non-Enzymatic Sensor for Quantitation of Anti-Cancer Substance Chicoric Acid Based on Bimetallic Nanoalloy with Polyetherimide-Capped Reduced Graphene Oxide
Q35919968An overview of the evidence and mechanisms of herb-drug interactions.
Q30382531Anti-viral properties and mode of action of standardized Echinacea purpurea extract against highly pathogenic avian influenza virus (H5N1, H7N7) and swine-origin H1N1 (S-OIV)
Q35494999Applications of the phytomedicine Echinacea purpurea (Purple Coneflower) in infectious diseases
Q35685529Bauer ketones 23 and 24 from Echinacea paradoxa var. paradoxa inhibit lipopolysaccharide-induced nitric oxide, prostaglandin E2 and cytokines in RAW264.7 mouse macrophages
Q92630140Biological Activity of New Cichoric Acid-Metal Complexes in Bacterial Strains, Yeast-Like Fungi, and Human Cell Cultures In Vitro
Q38235469Biotechnological production of caffeic acid derivatives from cell and organ cultures of Echinacea species
Q36771776Chicoric acid binds to two sites and decreases the activity of the YopH bacterial virulence factor
Q21131316Chicoric acid: chemistry, distribution, and production
Q34517159Commonly Used Dietary Supplements on Coagulation Function during Surgery
Q38323894Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products - part 2: Echinacea purpurea-Lavandula angustifolia.
Q36492104Cytokine- and interferon-modulating properties of Echinacea spp. root tinctures stored at -20 degrees C for 2 years
Q36495159Cytotoxic activity of polyacetylenes and polyenes isolated from roots of Echinacea pallida.
Q42805448Dodeca-2(E),4(E)-dienoic acid isobutylamide enhances glucose uptake in 3T3-L1 cells via activation of Akt signaling
Q38974893Drug interactions in HIV treatment: complementary & alternative medicines and over-the-counter products.
Q39664418Echinacea and trypanasomatid parasite interactions: growth-inhibitory and anti-inflammatory effects of Echinacea
Q57279724Echinacea biotechnology: advances, commercialization and future considerations
Q37157352Echinacea increases arginase activity and has anti-inflammatory properties in RAW 264.7 macrophage cells, indicative of alternative macrophage activation.
Q34074274Echinacea purpurea (L.) Moench modulates human T-cell cytokine response.
Q40379886Echinacea purpurea Extract Polarizes M1 Macrophages in Murine Bone Marrow-Derived Macrophages Through the Activation of JNK.
Q34467036Echinacea purpurea aerial extract alters course of influenza infection in mice.
Q42812590Echinacea purpurea root extract enhances the adipocyte differentiation of 3T3-L1 cells
Q36126286Echinacea purpurea significantly induces cytochrome P450 3A activity but does not alter lopinavir-ritonavir exposure in healthy subjects
Q35635920Echinacea purpurea: Pharmacology, phytochemistry and analysis methods.
Q37134477Echinacea sanguinea and Echinacea pallida extracts stimulate glucuronidation and basolateral transfer of Bauer alkamides 8 and 10 and ketone 24 and inhibit P-glycoprotein transporter in Caco-2 cells
Q36627223Echinacea species and alkamides inhibit prostaglandin E(2) production in RAW264.7 mouse macrophage cells
Q37198076Echinacea tennesseensis ethanol tinctures harbor cytokine- and proliferation-enhancing capacities
Q33752069Echinacea-induced cytosolic Ca2+ elevation in HEK293.
Q55617078Echinacea—A Source of Potent Antivirals for Respiratory Virus Infections.
Q39326895Effect of SAMITAL® in the treatment of chemotherapy-induced mucositis in adult oncohematological patients
Q37088260Effects of chemically characterized fractions from aerial parts of Echinacea purpurea and E. angustifolia on myelopoiesis in rats
Q43983228Effects of cichoric acid extract from Echinacea purpurea on collagen-induced arthritis in rats
Q37421665Endogenous levels of Echinacea alkylamides and ketones are important contributors to the inhibition of prostaglandin E2 and nitric oxide production in cultured macrophages.
Q34306204Evaluation of documented drug interactions and contraindications associated with herbs and dietary supplements: a systematic literature review
Q40406513Evaluation of immunomodulatory and anti-inflammatory effects and phytochemical screening of Alternanthera tenella Colla (Amaranthaceae) aqueous extracts.
Q46521143Free amino acids in botanicals and botanical preparations.
Q24656624Gauging the clinical significance of P-glycoprotein-mediated herb-drug interactions: comparative effects of St. John's wort, Echinacea, clarithromycin, and rifampin on digoxin pharmacokinetics
Q34483552Herb-drug interaction between Echinacea purpurea and darunavir-ritonavir in HIV-infected patients
Q36276879Herb-drug interaction between Echinacea purpurea and etravirine in HIV-infected patients
Q38543351Herbal hepatotoxicity: current status, examples, and challenges.
Q41726314Hyperspectral imaging and chemometric modeling of echinacea - a novel approach in the quality control of herbal medicines.
Q64978528In vitro and in vivo studies of the immunomodulatory effect of Echinacea purpurea on dendritic cells.
Q39545238In vitro inhibition of Eimeria tenella invasion of epithelial cells by phytochemicals.
Q51032481In vivo screening of five phytochemicals/extracts and a fungal immunomodulatory protein against colibacillosis in broilers.
Q44689414In vivo screening of four phytochemicals/extracts and a fungal immunomodulatory protein against an Eimeria acervulina infection in broilers.
Q42005590Induction of tetraploids from petiole explants through colchicine treatments in Echinacea purpurea L.
Q92097925Laboratory-derived formulations of Echinacea angustifolia roots lack preventive and treatment efficacy against experimental rhinovirus infections of healthy volunteers
Q39403596Liver immunology and herbal treatment.
Q28066772Medicinal plants--prophylactic and therapeutic options for gastrointestinal and respiratory diseases in calves and piglets? A systematic review
Q37052516Metabolic profiling of echinacea genotypes and a test of alternative taxonomic treatments
Q49484250MicroRNA-655-3p regulates Echinacea purpurea mediated activation of ABCG2.
Q91671179Modulation of Diabetes Mellitus-Induced Male Rat Reproductive Dysfunction with Micro-Nanoencapsulated Echinacea purpurea Ethanol Extract
Q36050847Mucosal and blood-brain barrier transport kinetics of the plant N-alkylamide spilanthol using in vitro and in vivo models.
Q38913421Novel TRAIL sensitizer Taraxacum officinale F.H. Wigg enhances TRAIL-induced apoptosis in Huh7 cells
Q37283479Overview of Botanical Status in EU, USA, and Thailand
Q36478368PHENETIC COMPARISON OF SEVEN Echinacea SPECIES BASED ON IMMUNOMODULATORY CHARACTERISTICS
Q38574619Pharmacokinetic Herb-Drug Interactions: Insight into Mechanisms and Consequences
Q33795072Pharmacokinetic and pharmacodynamic interactions of echinacea and policosanol with warfarin in healthy subjects
Q47160659Plant-endophytes interaction influences the secondary metabolism in Echinacea purpurea (L.) Moench: an in vitro model.
Q47198730Possible Mechanisms of the Prevention of Doxorubicin Toxicity by Cichoric Acid-Antioxidant Nutrient
Q34485025Quantification of phenylpropanoids in commercial Echinacea products using TLC with video densitometry as detection technique and ANN for data modelling.
Q42487432Rabbit dietary supplementation with pale purple coneflower. 1. Effects on the reproductive performance and immune parameters of does
Q40979411Rabbit dietary supplementation with pale purple coneflower. 2. Effects on the performances, bacterial community, blood parameters and immunity of growing rabbits.
Q35645820Randomised, double blind, placebo-controlled trial of echinacea supplementation in air travellers
Q41839742Safety of Herbal Medicinal Products: Echinacea and Selected Alkylamides Do Not Induce CYP3A4 mRNA Expression
Q33631686Secondary Metabolites from Fungal Endophytes of Echinacea purpurea Suppress Cytokine Secretion by Macrophage-Type Cells
Q47896744Simultaneous Determination of Seven Phenolic Acids in Rat Plasma Using UHPLC-ESI-MS/MS after Oral Administration of Echinacea purpurea Extract.
Q92753246Supplementation of Plants with Immunomodulatory Properties during Pregnancy and Lactation-Maternal and Offspring Health Effects
Q36120667Synthesis and natural distribution of anti-inflammatory alkamides from Echinacea.
Q42641602The anxiolytic potential and psychotropic side effects of an echinacea preparation in laboratory animals and healthy volunteers.
Q49108941The effects of an Echinacea preparation on synaptic transmission and the firing properties of CA1 pyramidal cells in the hippocampus
Q92215521The influence of Echinacea purpurea leaf microbiota on chicoric acid level
Q39657299The potential use of Echinacea in acne: control of Propionibacterium acnes growth and inflammation
Q36002697The synthesis and natural distribution of the major ketone constituents in Echinacea pallida
Q93111390Tissue specificity and differential effects on in vitro plant growth of single bacterial endophytes isolated from the roots, leaves and rhizospheric soil of Echinacea purpurea
Q35990811Year-and-a-half old, dried Echinacea roots retain cytokine-modulating capabilities in an in vitro human older adult model of influenza vaccination.

Search more.