The many roles of an RNA editor.

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The many roles of an RNA editor. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1025777197
P356DOI10.1038/35098584
P698PubMed publication ID11715042

P50authorMary A O'ConnellQ55143472
Angela GalloQ55299960
P2093author name stringKeegan LP
P2860cites workBiased hypermutation of viral RNA genomes could be due to unwinding/modification of double-stranded RNA.Q52868697
Regulation of the expression of the H+-ATPase genes PMA1 and PMA2 during growth and effects of octanoic acid in Saccharomyces cerevisiaeQ59592190
The delta agentQ70448399
Early-onset epilepsy and postnatal lethality associated with an editing-deficient GluR-B allele in miceQ71593532
RNA hyperediting and alternative splicing of hematopoietic cell phosphatase (PTPN6) gene in acute myeloid leukemiaQ72992416
HIV-1 RNA editing, hypermutation, and error-prone reverse transcriptionQ73728115
Sequence elements required for apolipoprotein B mRNA editing enhancement activity from chicken enterocytesQ77911808
APOBEC-2, a cardiac- and skeletal muscle-specific member of the cytidine deaminase supergene familyQ22010252
Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA.Q22253163
Purification and molecular cloning of a novel essential component of the apolipoprotein B mRNA editing enzyme-complexQ22253986
A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domainsQ22254191
Isolation, tissue distribution, and chromosomal localization of the human activation-induced cytidine deaminase (AID) geneQ24290122
Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)Q24290325
Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminaseQ24311306
Purification of human double-stranded RNA-specific editase 1 (hRED1) involved in editing of brain glutamate receptor B pre-mRNAQ24312651
Editing of glutamate receptor B subunit ion channel RNAs by four alternatively spliced DRADA2 double-stranded RNA adenosine deaminasesQ24314530
Evolutionary origins of apoB mRNA editing: catalysis by a cytidine deaminase that has acquired a novel RNA-binding motif at its active siteQ24316081
Functionally distinct double-stranded RNA-binding domains associated with alternative splice site variants of the interferon-inducible double-stranded RNA-specific adenosine deaminaseQ24318275
Dimeric structure of a human apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its geneQ24319079
Small nucleolar RNA-guided post-transcriptional modification of cellular RNAsQ24535572
Substrate recognition by ADAR1 and ADAR2Q24540028
The neurofibromatosis type I messenger RNA undergoes base-modification RNA editingQ24545914
Nucleolar factors direct the 2'-O-ribose methylation and pseudouridylation of U6 spliceosomal RNAQ24554419
The human but not the Xenopus RNA-editing enzyme ADAR1 has an atypical nuclear localization signal and displays the characteristics of a shuttling proteinQ24555715
Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editingQ24561760
A conserved double-stranded RNA-binding domainQ24563195
Molecular cloning of a human small intestinal apolipoprotein B mRNA editing proteinQ24609696
Apolipoprotein B RNA editing enzyme-deficient mice are viable despite alterations in lipoprotein metabolismQ24616407
Induction of RNA editing at heterologous sites by sequences in apolipoprotein B mRNAQ24629461
Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminaseQ24652788
A Z-DNA binding domain present in the human editing enzyme, double-stranded RNA adenosine deaminaseQ24654692
Human RNA-specific adenosine deaminase ADAR1 transcripts possess alternative exon 1 structures that initiate from different promoters, one constitutively active and the other interferon inducibleQ24670551
Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organizationQ24673252
Crystal structure of the Zalpha domain of the human editing enzyme ADAR1 bound to left-handed Z-DNAQ27618555
RNA recognition by a Staufen double-stranded RNA-binding domainQ27621605
The crystal structure of Haelll methyltransferase covalently complexed to DNA: An extrahelical cytosine and rearranged base pairingQ27729758
The genome sequence of Drosophila melanogasterQ27860796
An adenosine deaminase that generates inosine at the wobble position of tRNAsQ27936395
Tad1p, a yeast tRNA-specific adenosine deaminase, is related to the mammalian pre-mRNA editing enzymes ADAR1 and ADAR2.Q27939647
The DNA sequence of human chromosome 22Q28139873
Identification of GRY-RBP as an apolipoprotein B RNA-binding protein that interacts with both apobec-1 and apobec-1 complementation factor to modulate C to U editingQ28141214
Psoriasis upregulated phorbolin-1 shares structural but not functional similarity to the mRNA-editing protein apobec-1Q28143382
RNA editing: cytidine to uridine conversion in apolipoprotein B mRNAQ28143524
RNA editing of the human serotonin 5-HT2C receptor. alterations in suicide and implications for serotonergic pharmacotherapyQ28209686
The fate of dsRNA in the nucleus: a p54(nrb)-containing complex mediates the nuclear retention of promiscuously A-to-I edited RNAsQ28214585
Regulation of serotonin-2C receptor G-protein coupling by RNA editingQ28238375
Control of kinetic properties of AMPA receptor channels by nuclear RNA editingQ28242756
RNA editing of AMPA receptor subunit GluR-B: a base-paired intron-exon structure determines position and efficiencyQ28257748
A mammalian RNA editing enzymeQ28273153
RNA editing of the 5-HT(2C) receptor is reduced in schizophreniaQ43666810
Biased hypermutation and other genetic changes in defective measles viruses in human brain infectionsQ45060135
The mechanism of adenosine to inosine conversion by the double-stranded RNA unwinding/modifying activity: a high-performance liquid chromatography-mass spectrometry analysisQ45160107
A developmentally regulated activity that unwinds RNA duplexesQ45204994
Editing for an AMPA receptor subunit RNA in prefrontal cortex and striatum in Alzheimer's disease, Huntington's disease and schizophreniaQ45291783
RED2, a brain-specific member of the RNA-specific adenosine deaminase familyQ45345704
Measles virus editing provides an additional cysteine-rich proteinQ45839492
Two efficiency elements flanking the editing site of cytidine 6666 in the apolipoprotein B mRNA support mooring-dependent editingQ46625530
A-to-I pre-mRNA editing in Drosophila is primarily involved in adult nervous system function and integrityQ47070866
Distinct promoters induce APOBEC-1 expression in rat liver and intestineQ47810171
Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codonQ48336804
Detection of inosine in messenger RNA by inosine-specific cleavageQ48657666
Analysis of the RNA-editing reaction of ADAR2 with structural and fluorescent analogues of the GluR-B R/G editing site.Q50509104
Antisense RNA injections in fertilized frog eggs reveal an RNA duplex unwinding activity.Q52257659
RNA editing in brain controls a determinant of ion flow in glutamate-gated channelsQ28279138
Complete phenotypic characterization of apobec-1 knockout mice with a wild-type genetic background and a human apolipoprotein B transgenic background, and restoration of apolipoprotein B mRNA editing by somatic gene transfer of Apobec-1Q28291031
A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestineQ28301876
Specific cleavage of hyper-edited dsRNAsQ28345098
Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cellsQ28509339
Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesisQ28510594
Molecular cloning of an apolipoprotein B messenger RNA editing proteinQ28580321
Regulation of alternative splicing by RNA editingQ28584284
A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzymeQ28589367
Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48Q28594252
Nuclear antisense RNA induces extensive adenosine modifications and nuclear retention of target transcriptsQ29035948
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzymeQ29547201
Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2Q29619718
Towards an understanding of somatic hypermutationQ32067279
Inosine exists in mRNA at tissue-specific levels and is most abundant in brain mRNAQ33888345
Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animalsQ33985264
Major transcript of the frameshifted coxII gene from trypanosome mitochondria contains four nucleotides that are not encoded in the DNA.Q34048640
Chicken double-stranded RNA adenosine deaminase has apparent specificity for Z-DNAQ34064821
Imprinted expression of small nucleolar RNAs in brain: time for RNomicsQ34106189
Quality control of mRNA functionQ34156109
RNA editing by base deamination: more enzymes, more targets, new mysteriesQ34282470
Linking class-switch recombination with somatic hypermutationQ34297090
dADAR, a Drosophila double-stranded RNA-specific adenosine deaminase is highly developmentally regulated and is itself a target for RNA editingQ34362817
Synthetic polynucleotides and the amino acid code. VQ36394547
Double-stranded RNA unwinding and modifying activity is detected ubiquitously in primary tissues and cell linesQ36730234
Long RNA hairpins that contain inosine are present in Caenorhabditis elegans poly(A)+ RNAQ37195281
Synthetic substrate analogs for the RNA-editing adenosine deaminase ADAR-2.Q38323240
RNA editing generates a diverse array of transcripts encoding squid Kv2 K+ channels with altered functional propertiesQ38555786
Cytosine nucleoside/nucleotide deaminases and apolipoprotein B mRNA editing.Q40762415
The role of RNA editing in controlling glutamate receptor channel properties.Q40923774
Characterization of the 5'-flanking region of the human RNA-specific adenosine deaminase ADAR1 gene and identification of an interferon-inducible ADAR1 promoterQ40964352
RNA editing, introns and evolutionQ41064640
RNA editing of hepatitis delta virus antigenome by dsRNA-adenosine deaminaseQ41206734
Alternative mRNA splicing and differential promoter utilization determine tissue-specific expression of the apolipoprotein B mRNA-editing protein (Apobec1) gene in mice. Structure and evolution of Apobec1 and related nucleoside/nucleotide deaminasesQ41336434
Phylogenetic analysis of the apolipoprotein B mRNA-editing region. Evidence for a secondary structure between the mooring sequence and the 3' efficiency elementQ41704284
Molecular basis of double-stranded RNA-protein interactions: structure of a dsRNA-binding domain complexed with dsRNA.Q41877792
Mutagenic analysis of double-stranded RNA adenosine deaminase, a candidate enzyme for RNA editing of glutamate-gated ion channel transcriptsQ42065980
A Drosophila calcium channel alpha1 subunit gene maps to a genetic locus associated with behavioral and visual defectsQ42647731
Modifications of U2 snRNA are required for snRNP assembly and pre-mRNA splicingQ42656253
Diversification of Drosophila chloride channel gene by multiple posttranscriptional mRNA modificationsQ42689716
Generation of G-to-A and C-to-U changes in HIV-1 transcripts by RNA editingQ43497010
P433issue11
P304page(s)869-878
P577publication date2001-11-01
P1433published inNature Reviews GeneticsQ1071824
P1476titleThe many roles of an RNA editor
P478volume2

Reverse relations

cites work (P2860)
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