Exogenous addition of arachidonic acid to the culture media enhances the functionality of dendritic cells for their possible use in cancer immunotherapy

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Exogenous addition of arachidonic acid to the culture media enhances the functionality of dendritic cells for their possible use in cancer immunotherapy is …
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scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...9k1759K
P356DOI10.1371/JOURNAL.PONE.0111759
P932PMC publication ID4219773
P698PubMed publication ID25369453
P5875ResearchGate publication ID267870934

P2093author name stringLalita Limaye
Vaijayanti Kale
Jeetendra Kumar
Rupali Gurav
P2860cites workThe chemokine receptor CCR7 activates in dendritic cells two signaling modules that independently regulate chemotaxis and migratory speedQ24298508
Reciprocal crosstalk between dendritic cells and natural killer cells under the effects of PGE2 in immunity and immunopathologyQ26825075
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Cancer immunotherapy via dendritic cellsQ29615444
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Generation of large numbers of fully mature and stable dendritic cells from leukapheresis products for clinical applicationQ33536357
Dendritic cells in cancer immunotherapyQ33932695
Gene regulation and chromatin remodeling by IL-12 and type I IFN in programming for CD8 T cell effector function and memoryQ33946269
Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cellsQ34141893
Mature autologous dendritic cell vaccines in advanced non-small cell lung cancer: a phase I pilot study.Q35102873
Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models.Q35140717
Dendritic cells: limited potential in immunotherapyQ35913609
Trial watch: Dendritic cell-based interventions for cancer therapyQ36388529
Generation, migration and function of circulating dendritic cellsQ36507785
Cancer immunotherapy by dendritic cellsQ37272237
Costimulation of dectin-1 and DC-SIGN triggers the arachidonic acid cascade in human monocyte-derived dendritic cellsQ39994877
RNA loading of leukemic antigens into cord blood-derived dendritic cells for immunotherapy.Q40252007
Long-term culture of human CD34(+) progenitors with FLT3-ligand, thrombopoietin, and stem cell factor induces extensive amplification of a CD34(-)CD14(-) and a CD34(-)CD14(+) dendritic cell precursor.Q40820456
Origin, maturation and antigen presenting function of dendritic cells.Q40906220
Dendritic cells in cancer immunotherapy: vaccines or autologous transplants?Q41520681
The disabled dendritic cellQ43568386
The first 1000 dendritic cell vaccinees.Q50736412
A simple two-step culture system for the large-scale generation of mature and functional dendritic cells from umbilical cord blood CD34+ cells.Q50743099
Stem cell factor augments tumor necrosis factor-granulocyte-macrophage colony-stimulating factor-mediated dendritic cell hematopoiesis.Q51126171
Expansion of dendritic cell precursors from human CD34(+) progenitor cells isolated from healthy donor blood; growth factor combination determines proliferation rate and functional outcome.Q52011374
Selective generation of different dendritic cell precursors from CD34+ cells by interleukin-6 and interleukin-3.Q52087796
Prostaglandin E2 induces the final maturation of IL-12-deficient CD1a+CD83+ dendritic cells: the levels of IL-12 are determined during the final dendritic cell maturation and are resistant to further modulation.Q52905310
Limited Amounts of Dendritic Cells Migrate into the T-Cell Area of Lymph Nodes but Have High Immune Activating Potential in Melanoma PatientsQ58619964
A Critical Role for Prostaglandin E2 in Podosome Dissolution and Induction of High-Speed Migration during Dendritic Cell MaturationQ58620009
The JAM test. A simple assay for DNA fragmentation and cell deathQ67814814
Stem cell factor and the regulation of dendritic cell production from CD34+ progenitors in bone marrow and cord bloodQ71098982
Migration of human dendritic cells after injection in patients with metastatic malignanciesQ77804763
Cyclooxygenase-2 inhibition attenuates antibody responses against human papillomavirus-like particlesQ79370189
The JAM Test and its daughter P-JAM: simple tests of DNA fragmentation to measure cell death and stasisQ80092940
In vitro generation of functional dendritic cells from human umbilical cord blood CD34+ cells by a 2-step culture methodQ80995433
A large number of mature and functional dendritic cells can be efficiently generated from umbilical cord blood-derived mononuclear cells by a simple two-step culture methodQ84289985
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectdendritic cellQ506253
immunotherapyQ1427096
P304page(s)e111759
P577publication date2014-11-04
P1433published inPLOS OneQ564954
P1476titleExogenous addition of arachidonic acid to the culture media enhances the functionality of dendritic cells for their possible use in cancer immunotherapy
P478volume9

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Q36093456Umbilical cord blood-derived CD11c(+) dendritic cells could serve as an alternative allogeneic source of dendritic cells for cancer immunotherapycites workP2860

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