Mitochondrial ion channels: gatekeepers of life and death

scientific article

Mitochondrial ion channels: gatekeepers of life and death is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1152/PHYSIOL.00020.2005
P932PMC publication ID2739045
P698PubMed publication ID16174870
P5875ResearchGate publication ID7588788

P2093author name stringMiguel A Aon
Sonia Cortassa
Brian O'Rourke
P2860cites workBasic Mechanisms of Cardiac Impulse Propagation and Associated ArrhythmiasQ22337019
Oligomeric Bax is a component of the putative cytochrome c release channel MAC, mitochondrial apoptosis-induced channelQ24523479
Free radicals in the physiological control of cell functionQ27860480
Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1Q28141355
Mitochondrial ATP-sensitive potassium channels inhibit apoptosis induced by oxidative stress in cardiac cellsQ28203141
The ADP/ATP translocator is not essential for the mitochondrial permeability transition poreQ28241418
ATP-sensitive K+ channel in the mitochondrial inner membraneQ28284871
A novel potassium channel in lymphocyte mitochondriaQ28301096
Mitochondria and apoptosisQ29547905
Mitochondrial formation of reactive oxygen speciesQ29547906
The mitochondrial permeability transition pore and its role in cell deathQ29614183
Conformational changes in the mitochondrial channel protein, VDAC, and their functional implicationsQ30176170
The mitochondrial origin of postischemic arrhythmiasQ30476348
A simulation study of the effects of cardiac anatomy in ventricular fibrillationQ30528886
Fluctuations in mitochondrial membrane potential caused by repetitive gating of the permeability transition poreQ30785418
Protective effects of low and high doses of cyclosporin A against reoxygenation injury in isolated rat cardiomyocytes are associated with differential effects on mitochondrial calcium levelsQ30855882
A mitochondrial oscillator dependent on reactive oxygen speciesQ31109059
Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytesQ31154504
Bioenergetic consequences of opening the ATP-sensitive K(+) channel of heart mitochondriaQ31833702
Preconditioning protects by inhibiting the mitochondrial permeability transitionQ33201290
Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell deathQ33538979
Redox regulation of signal transduction in cardiac and smooth muscleQ33545136
ATP-Sensitive potassium channels: a review of their cardioprotective pharmacologyQ33886193
VDAC channels mediate and gate the flow of ATP: implications for the regulation of mitochondrial functionQ33915365
Identification of a ryanodine receptor in rat heart mitochondriaQ33942032
An integrated model of cardiac mitochondrial energy metabolism and calcium dynamicsQ33947602
Protection of cardiac mitochondria by diazoxide and protein kinase C: implications for ischemic preconditioningQ34017639
Multiple conductance channel activity of wild-type and voltage-dependent anion-selective channel (VDAC)-less yeast mitochondriaQ34129593
The 'harmless' release of cytochrome c.Q34139341
Imaging the permeability pore transition in single mitochondriaQ34167671
Comparison of the TIM and TOM Channel Activities of the Mitochondrial Protein Import ComplexesQ34181068
Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition poreQ34327908
Mitochondrial Ca2+-activated K+ channels in cardiac myocytes: a mechanism of the cardioprotective effect and modulation by protein kinase A.Q34380288
The mitochondrial death/life regulator in apoptosis and necrosisQ34465435
Cell metabolism in the regulation of programmed cell deathQ34537642
Properties of the inner membrane anion channel in intact mitochondriaQ35332817
Primary and secondary signaling pathways in early preconditioning that converge on the mitochondria to produce cardioprotectionQ35625497
Evidence for mitochondrial K+ channels and their role in cardioprotectionQ35682888
Outer mitochondrial membrane permeability can regulate coupled respiration and cell survivalQ35690379
Laser-stimulated fluorescence of submicrometer regions within single mitochondria of rhodamine-treated myocardial cells in cultureQ36277698
Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytesQ36368961
Experimental models of ventricular tachycardia and fibrillation caused by ischemia and infarctionQ36730113
HMR 1883, a novel cardioselective inhibitor of the ATP-sensitive potassium channel. Part II: effects on susceptibility to ventricular fibrillation induced by myocardial ischemia in conscious dogs.Q36898405
Percolation and criticality in a mitochondrial network.Q37357761
Ca2+ as a second messenger within mitochondria of the heart and other tissuesQ37918891
Activity of the mitochondrial multiple conductance channel is independent of the adenine nucleotide translocatorQ38563948
The regulation of the matrix volume of mammalian mitochondria in vivo and in vitro and its role in the control of mitochondrial metabolismQ38608271
Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor.Q39821682
Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescenceQ40137371
Electrophysiology of the inner mitochondrial membraneQ40398891
Opening of potassium channels modulates mitochondrial function in rat skeletal muscleQ40686178
Actinomycin D-induced apoptosis involves the potassium channel Kv1.3.Q40714099
Ca2+-activated K channel of the BK-type in the inner mitochondrial membrane of a human glioma cell lineQ40961573
Two high conductance channels of the mitochondrial inner membrane are independent of the human mitochondrial genomeQ41048553
Na-H exchange in myocardium: effects of hypoxia and acidification on Na and Ca.Q41202421
Patch-clamping of the inner mitochondrial membrane reveals a voltage-dependent ion channelQ41251219
Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injuryQ41601375
A redox-based mechanism for cardioprotection induced by ischemic preconditioning in perfused rat heartQ41676332
Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondriaQ41829151
Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusionQ41977320
Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state.Q42123867
Mitochondrial ATP-sensitive potassium channels attenuate matrix Ca(2+) overload during simulated ischemia and reperfusion: possible mechanism of cardioprotectionQ43794479
A large Ca2+-dependent channel formed by recombinant ADP/ATP carrier from Neurospora crassa resembles the mitochondrial permeability transition poreQ44148106
The mitochondrial megachannel is the permeability transition poreQ44175602
Cytoprotective role of Ca2+- activated K+ channels in the cardiac inner mitochondrial membraneQ44201844
Role of calcium in metabolic signaling between cardiac sarcoplasmic reticulum and mitochondria in vitroQ44279066
Regulation of brain mitochondrial H2O2 production by membrane potential and NAD(P)H redox state.Q44545123
Mitochondrial membrane potentials in ischemic heartsQ44678913
The mitochondrial calcium uniporter is a highly selective ion channel.Q44737530
Opening of Ca2+-activated K+ channels triggers early and delayed preconditioning against I/R injury independent of NOS in mice.Q44903215
Glucose flux rate regulates onset of ischemic contracture in globally underperfused rat heartsQ45731326
Noninvasive fluorometric measurement of mitochondrial membrane potential in isolated working rat hearts during ischemia and reperfusionQ46094206
Ionic permeability of the mitochondrial outer membraneQ48590234
108-pS channel in brown fat mitochondria might Be identical to the inner membrane anion channel.Q50527462
Sulfhydryl redox state affects susceptibility to ischemia and sarcoplasmic reticulum Ca2+ release in rat heart. Implications for ischemic preconditioning.Q50755530
On the regulation of K+ uniport in intact mitochondria by adenine nucleotides and nucleotide analogs.Q50785794
On the inhibition of the mitochondrial inner membrane anion uniporter by cationic amphiphiles and other drugs.Q52541163
Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes.Q52563106
Imaging the mitochondrial permeability transition pore in intact cells.Q53938805
Mitochondria Are Excitable Organelles Capable of Generating and Conveying Electrical and Calcium SignalsQ53967833
Reconstitution and partial purification of the glibenclamide-sensitive, ATP-dependent K+ channel from rat liver and beef heart mitochondriaQ67965066
Na+ accumulation increases Ca2+ overload and impairs function in anoxic rat heartQ68455538
Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondriaQ70080329
Mitochondrial ADP/ATP carrier can be reversibly converted into a large channel by Ca2+Q71186017
Cation transport in mitochondria--the potassium cycleQ71211440
The Effects of the ATP-Dependent Potassium Channel Antagonist, Glyburide, on Coronary Blood Flow and Susceptibility to Ventricular Fibrillation in Unanesthetized DogsQ72069405
Oscillations of membrane current and excitability driven by metabolic oscillations in heart cellsQ72112188
Oxygen radicals released during ischemic preconditioning contribute to cardioprotection in the rabbit myocardiumQ73088324
Mitochondrial permeability transition in hepatocytes induced by t-BuOOH: NAD(P)H and reactive oxygen speciesQ73322667
Effects of carbonyl cyanide phenylhydrazones on two mitochondrial ion channel activitiesQ73701510
Intracellular free calcium and mitochondrial membrane potential in ischemia/reperfusion and preconditioningQ73910285
State-dependent inhibition of the mitochondrial KATP channel by glyburide and 5-hydroxydecanoateQ74567396
Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytesQ74771773
P304page(s)303-315
P577publication date2005-10-01
P1433published inPhysiologyQ1091804
P1476titleMitochondrial ion channels: gatekeepers of life and death
P478volume20

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