Inhibition of hepatitis B virus and induction of hepatoma cell apoptosis by ASGPR-directed delivery of shRNAs

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Inhibition of hepatitis B virus and induction of hepatoma cell apoptosis by ASGPR-directed delivery of shRNAs is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...746096M
P356DOI10.1371/JOURNAL.PONE.0046096
P932PMC publication ID3477153
P698PubMed publication ID23094023
P5875ResearchGate publication ID232649706

P50authorHongbo LiuQ59161550
P2093author name stringChunmei Huang
Qin Ning
Guanxin Shen
Huifen Zhu
Chuan Shi
Ping Lei
Lifang Sun
Chun Zhou
Lu Yuan
Jingwei Ma
Xiongwen Wu
Xinxin Yao
P2860cites workExpression of survivin messenger RNA correlates with poor prognosis in patients with hepatocellular carcinomaQ53392249
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Galactosylated proteins are recognized by the liver according to the surface density of galactose moietiesQ72268146
Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptorsQ81772313
Mechanism of plasmid delivery by hydrodynamic tail vein injection. II. Morphological studiesQ83828293
HBXIP functions as a cofactor of survivin in apoptosis suppressionQ24303423
A novel anti-apoptosis gene, survivin, expressed in cancer and lymphomaQ24322614
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Killing the messenger: short RNAs that silence gene expressionQ28207880
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Hepatitis B virus protein X-induced expression of the CXC chemokine IP-10 is mediated through activation of NF-kappaB and increases migration of leukocytesQ33782559
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Expansion and contraction of the hepatitis B virus transcriptional template in infected chimpanzeesQ36605001
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Interleukin-32 expression induced by hepatitis B virus protein X is mediated through activation of NF-κBQ39560701
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Survivin knockdown by short hairpin RNA abrogates the growth of human hepatocellular carcinoma xenografts in nude miceQ39781729
Evaluation of specific delivery of chimeric phi29 pRNA/siRNA nanoparticles to multiple tumor cellsQ39788190
HBx protein induces expression of MIG and increases migration of leukocytes through activation of NF-kappaB.Q39892900
Systemic and specific delivery of small interfering RNAs to the liver mediated by apolipoprotein A-I.Q40144403
Hepatitis B virus X protein upregulates survivin expression in hepatoma tissues.Q40371259
The inhibition of apoptosis of hepatoma cells induced by HBx is mediated by up-regulation of survivin expressionQ40579658
High-throughput selection of effective RNAi probes for gene silencing.Q40629211
Inhibition of hepatitis B virus in mice by RNA interferenceQ40648698
Interferon-alpha response in chronic hepatitis B-transfected HepG2.2.15 cells is partially restored by lamivudine treatmentQ40969500
HBV cccDNA in patients' sera as an indicator for HBV reactivation and an early signal of liver damageQ41985642
Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy.Q44929883
Chromosome Remodeling Related to Hepatitis B Virus Replication in HepG2 CellsQ45368831
Hepatitis B virus X protein prevents apoptosis of hepatocellular carcinoma cells by upregulating SATB1 and HURP expressionQ45375369
Epidemiology of chronic hepatitis B virus infection, hepatocellular carcinoma, and hepatitis B virus-induced hepatocellular carcinomaQ45376920
HBx gene of hepatitis B virus induces liver cancer in transgenic miceQ45852802
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectHepatitis B virusQ6844
hepatocellular carcinomaQ1148337
P304page(s)e46096
P577publication date2012-10-19
P1433published inPLOS OneQ564954
P1476titleInhibition of hepatitis B virus and induction of hepatoma cell apoptosis by ASGPR-directed delivery of shRNAs
P478volume7

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cites work (P2860)
Q38271422Active radar guides missile to its target: receptor-based targeted treatment of hepatocellular carcinoma by nanoparticulate systems
Q42910343Diagnosis of abnormal biliary copper excretion by positron emission tomography with targeting of (64)Copper-asialofetuin complex in LEC rat model of Wilson's disease.
Q45233843Expression of cytokines in mouse hepatitis B virus X gene-transfected model
Q28085748Liver-targeted gene therapy: Approaches and challenges
Q40482454Variable asialoglycoprotein receptor 1 expression in liver disease: Implications for therapeutic intervention.

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