Expression of hepatocytic- and biliary-specific transcription factors in regenerating bile ducts during hepatocyte-to-biliary epithelial cell transdifferentiation

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Expression of hepatocytic- and biliary-specific transcription factors in regenerating bile ducts during hepatocyte-to-biliary epithelial cell transdifferentiation is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1050486143
P356DOI10.1186/1476-5926-9-9
P932PMC publication ID3014870
P698PubMed publication ID21126359
P5875ResearchGate publication ID49653287

P2093author name stringAnne Orr
George K Michalopoulos
William C Bowen
Pallavi B Limaye
Udayan M Apte
P2860cites workOC-2, a novel mammalian member of the ONECUT class of homeodomain transcription factors whose function in liver partially overlaps with that of hepatocyte nuclear factor-6Q22008694
Histological organization in hepatocyte organoid culturesQ28363410
Bile ductular damage induced by methylene dianiline inhibits oval cell activationQ28379156
Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndromeQ28512217
Isolation and characterization of a putative liver progenitor population after treatment of fetal rat hepatocytes with TGF-betaQ28582698
Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factorsQ28585487
Liver regenerationQ29614743
Molecular mechanisms of liver development and differentiationQ33796349
Ductular proliferation in liver tissues with severe chronic hepatitis B: an immunohistochemical studyQ34012736
Transcriptional regulation of liver developmentQ34043393
The forkhead transcription factor FoxO1 regulates proliferation and transdifferentiation of hepatic stellate cellsQ34615778
Hepatocytes undergo phenotypic transformation to biliary epithelium in organoid culturesQ35585322
Transdifferentiation of rat hepatocytes into biliary cells after bile duct ligation and toxic biliary injuryQ35677684
Long-term, near-total liver replacement by transplantation of isolated hepatocytes in rats treated with retrorsineQ35753154
Mechanisms of hepatocyte growth factor-mediated and epidermal growth factor-mediated signaling in transdifferentiation of rat hepatocytes to biliary epitheliumQ37041709
Morphogenetic competence of HNF4 alpha-deficient mouse hepatic cellsQ37059130
Generation and regeneration of cells of the liver and pancreasQ37341344
Transdifferentiation of mature rat hepatocytes into bile duct-like cells in vitroQ38585812
Ductular reaction in the liverQ40370388
Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha.Q40442109
The onecut transcription factor HNF6 is required for normal development of the biliary tractQ40740061
Liver-enriched transcription factors and hepatocyte differentiation.Q40993765
Expression of specific hepatocyte and cholangiocyte transcription factors in human liver disease and embryonic developmentQ41888107
A minimally toxic dose of methylene dianiline injures biliary epithelial cells in ratsQ42541275
Bile system morphogenesis defects and liver dysfunction upon targeted deletion of HNF1beta.Q43948844
2-acetylaminofluorene dose-dependent differentiation of rat oval cells into hepatocytes: confocal and electron microscopic studiesQ44880267
Control of hepatic differentiation by activin/TGFbeta signaling.Q53644028
Infusion of bile from methylene dianiline-treated rats into the common bile duct injures biliary epithelial cells of recipient ratsQ56948878
Liver regenerationQ63664803
Proliferation, apoptosis, and induction of hepatic transcription factors are characteristics of the early response of biliary epithelial (oval) cells to chemical carcinogensQ70869719
Identification of hepatocytic and bile ductular cell lineages and candidate stem cells in bipolar ductular reactions in cirrhotic human liverQ79839838
Bile duct destruction by 4,4'-diaminodiphenylmethane does not block the small hepatocyte-like progenitor cell response in retrorsine-exposed ratsQ80809793
Transdifferentiation into biliary ductular cells of hepatocytes transplanted into the spleenQ81129356
P304page(s)9
P577publication date2010-12-02
P1433published inComparative HepatologyQ15760004
P1476titleExpression of hepatocytic- and biliary-specific transcription factors in regenerating bile ducts during hepatocyte-to-biliary epithelial cell transdifferentiation
P478volume9

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cites work (P2860)
Q41816633Biliary fibrosis drives liver repopulation and phenotype transition of transplanted hepatocytes
Q46888741Cultured hepatocytes adopt progenitor characteristics and display bipotent capacity to repopulate the liver
Q37379473Ductular reaction-on-a-chip: Microfluidic co-cultures to study stem cell fate selection during liver injury
Q35578634Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration
Q38748470Immunohistochemical Analysis of the Stem Cell Marker LGR5 in Pediatric Liver Disease
Q34004322Immunohistochemical characterization of the hepatic progenitor cell compartment in medaka (Oryzias latipes) following hepatic injury
Q85895754Liver cancer: Intrahepatic cholangiocarcinoma--appearances can be deceiving
Q98238191Liver regeneration: biological and pathological mechanisms and implications
Q38180839Re-evaluation of liver stem/progenitor cells.
Q35631841Stem cells in liver diseases and cancer: recent advances on the path to new therapies