Glycomics: an integrated systems approach to structure-function relationships of glycans

scientific article

Glycomics: an integrated systems approach to structure-function relationships of glycans is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1030401633
P356DOI10.1038/NMETH807
P698PubMed publication ID16278650
P5875ResearchGate publication ID7488910

P50authorRahul RamanQ104477463
Ram SasisekharanQ114401807
P2093author name stringJames C Paulson
Ganesh Venkataraman
S Raguram
P2860cites workA novel beta1,3-N-acetylglucosaminyltransferase (beta3Gn-T8), which synthesizes poly-N-acetyllactosamine, is dramatically upregulated in colon cancerQ24336874
Printed covalent glycan array for ligand profiling of diverse glycan binding proteinsQ24559665
Helicobacter pylori SabA adhesin in persistent infection and chronic inflammationQ24650188
The KEGG resource for deciphering the genomeQ27860687
Mammalian Brain Morphogenesis and Midline Axon Guidance Require Heparan SulfateQ28588474
Genetically altered mice with different sialyltransferase deficiencies show tissue-specific alterations in sialylation and sialic acid 9-O-acetylationQ28589584
Detection of oligosaccharides labeled with cyanine dyes using matrix-assisted laser desorption/ionization mass spectrometryQ30765401
N-Glycans of Caenorhabditis elegans are specific to developmental stagesQ30784293
Sequencing complex polysaccharidesQ30791276
The fine structure of Caenorhabditis elegans N-glycansQ30859339
Data mining the protein data bank: automatic detection and assignment of carbohydrate structuresQ30910965
Development of a mass fingerprinting tool for automated interpretation of oligosaccharide fragmentation dataQ30936226
A high-performance liquid chromatography based strategy for rapid, sensitive sequencing of N-linked oligosaccharide modifications to proteins in sodium dodecyl sulphate polyacrylamide electrophoresis gel bandsQ31027284
Characterization of a heparan sulfate octasaccharide that binds to herpes simplex virus type 1 glycoprotein D.Q31086120
LPS, TLR4 and infectious disease diversity.Q35988748
Structural insights into biological roles of protein-glycosaminoglycan interactionsQ36083300
Glycans in cancer and inflammation--potential for therapeutics and diagnosticsQ36148438
Siglecs in innate immunityQ36162931
Fuc-TVII is required for T helper 1 and T cytotoxic 1 lymphocyte selectin ligand expression and recruitment in inflammation, and together with Fuc-TIV regulates naive T cell trafficking to lymph nodesQ36376294
Microheterogeneity of the oligosaccharides carried by the recombinant bovine lactoferrin expressed in Mamestra brassicae cells.Q36875941
The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex.Q38328829
Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR.Q38340145
GlycoChip: multiarray for the study of carbohydrate-binding proteinsQ38343912
The carbohydrate sequence markup language (CabosML): an XML description of carbohydrate structuresQ38448493
GlycoFragment and GlycoSearchMS: web tools to support the interpretation of mass spectra of complex carbohydratesQ41010727
Exploring the glycan repertoire of genetically modified mice by isolation and profiling of the major glycan classes and nano-NMR analysis of glycan mixturesQ41750138
LINUCS: linear notation for unique description of carbohydrate sequencesQ42662231
Electron capture dissociation and infrared multiphoton dissociation MS/MS of an N-glycosylated tryptic peptic to yield complementary sequence informationQ43749887
An analytical and structural database provides a strategy for sequencing O-glycans from microgram quantities of glycoproteinsQ43968451
Caenorhabditis elegans early embryogenesis and vulval morphogenesis require chondroitin biosynthesisQ44450082
Recognition of bacterial glycosphingolipids by natural killer T cellsQ44582192
Alpha(1,3)fucosyltransferases FucT-IV and FucT-VII control susceptibility to atherosclerosis in apolipoprotein E-/- miceQ45016522
Electrospray ionization ion trap mass spectrometry for structural characterization of oligosaccharides derivatized with 2-aminobenzamideQ46415900
Chemoenzymatic synthesis of 2-azidoethyl-ganglio-oligosaccharides GD3, GT3, GM2, GD2, GT2, GM1, and GD1a.Q46591599
Application of a new probabilistic model for recognizing complex patterns in glycansQ48534156
A novel computational approach to integrate NMR spectroscopy and capillary electrophoresis for structure assignment of heparin and heparan sulfate oligosaccharidesQ48727498
Coupling of fully automated chip electrospray to Fourier transform ion cyclotron resonance mass spectrometry for high-performance glycoscreening and sequencing.Q51576759
Bioinformatics for glycomics: status, methods, requirements and perspectives.Q51993816
Combined Quantitative 1H and 13C Nuclear Magnetic Resonance Spectroscopy for Characterization of Heparin PreparationsQ57563823
Automated structural assignment of derivatized complex N-linked oligosaccharides from tandem mass spectraQ31107125
Structural characterization of the GM1 ganglioside by infrared multiphoton dissociation, electron capture dissociation, and electron detachment dissociation electrospray ionization FT-ICR MS/MS.Q31166047
Glycoprotein structure determination by mass spectrometryQ31884620
Automated solid-phase synthesis of oligosaccharidesQ32062090
Determination of N-glycosylation sites and site heterogeneity in glycoproteinsQ33196610
Fully automated chip-based mass spectrometry for complex carbohydrate system analysisQ33200590
Fragmentation characteristics of permethylated oligosaccharides using a matrix-assisted laser desorption/ionization two-stage time-of-flight (TOF/TOF) tandem mass spectrometerQ33207873
Automatic annotation of matrix-assisted laser desorption/ionization N-glycan spectraQ33211520
A synthetic antithrombin III binding pentasaccharide is now a drug! What comes next?Q33361287
Tumor cell surface heparan sulfate as cryptic promoters or inhibitors of tumor growth and metastasisQ33894102
Heparin and heparan sulfate: biosynthesis, structure and functionQ33927046
Core 3 synthase is down-regulated in colon carcinoma and profoundly suppresses the metastatic potential of carcinoma cells.Q33934190
The Molecule Pages databaseQ34164196
Custom microarray for glycobiologists: considerations for glycosyltransferase gene expression profiling.Q34185913
Glycosylation and the immune systemQ34195578
Recent advances in the structural biology of chondroitin sulfate and dermatan sulfateQ34271235
GlycoSuiteDB: a new curated relational database of glycoprotein glycan structures and their biological sourcesQ34315781
Emerging views of heparan sulfate glycosaminoglycan structure/activity relationships modulating dynamic biological functionsQ34536524
Roles of heparan-sulphate glycosaminoglycans in cancerQ34718195
Automated interpretation of MS/MS spectra of oligosaccharides.Q34803622
Structure of vaccinia complement protein in complex with heparin and potential implications for complement regulationQ34829635
Siglecs: sialic-acid-binding immunoglobulin-like lectins in cell-cell interactions and signalling.Q35015987
A genetic approach to Mammalian glycan functionQ35099563
Carbohydrate microarrays - a new set of technologies at the frontiers of glycomicsQ35564044
Structural and conformational aspects of the anticoagulant and anti-thrombotic activity of heparin and dermatan sulfateQ35743476
Role of glycosylation in developmentQ35799981
Application of Fourier transform ion cyclotron resonance mass spectrometry to oligosaccharidesQ35897299
Sugar-mediated ligand-receptor interactions in the immune systemQ35902884
Glycomics: a pathway to a class of new and improved therapeuticsQ35906116
Lectin-based structural glycomics: glycoproteomics and glycan profilingQ35910289
Chemoenzymatic synthesis of oligosaccharides and glycoproteinsQ35950697
Cell surface biology mediated by low affinity multivalent protein-glycan interactionsQ35958529
Functions of heparan sulfate proteoglycans in cell signaling during developmentQ35962679
P433issue11
P304page(s)817-824
P577publication date2005-11-01
P1433published inNature MethodsQ680640
P1476titleGlycomics: an integrated systems approach to structure-function relationships of glycans
P478volume2

Reverse relations

cites work (P2860)
Q47131624'Borono-lectin' based engineering as a versatile platform for biomedical applications
Q41175994A catalytic role of heparin within the extracellular matrix.
Q28473002A computational approach for deciphering the organization of glycosaminoglycans
Q55433078A novel probe based on phenylboronic acid functionalized carbon nanotubes for ultrasensitive carbohydrate determination in biofluids and semi-solid biotissues.
Q34776041A recombinant horseshoe crab plasma lectin recognizes specific pathogen-associated molecular patterns of bacteria through rhamnose
Q36874432A synthetic trivalent hapten that aggregates anti-2,4-DNP IgG into bicyclic trimers
Q43435251A triazatruxene-based glycocluster as a fluorescent sensor for concanavalin A.
Q49047025Alteration in N-glycomics during mouse aging: a role for FUT8.
Q34930770Analysis and validation of carbohydrate three-dimensional structures
Q53625004Analysis of glycosaminoglycan-derived, precolumn, 2-aminoacridone-labeled disaccharides with LC-fluorescence and LC-MS detection.
Q36401922Analysis of glycosaminoglycans in stem cell glycomics
Q43120650Analysis of lectin binding to glycolipid complexes using combinatorial glycoarrays
Q64102367Analysis of α-Dystroglycan/LG Domain Binding Modes: Investigating Protein Motifs That Regulate the Affinity of Isolated LG Domains
Q34155026Annotation of a serum N-glycan library for rapid identification of structures
Q27690218Application of microarrays for deciphering the structure and function of the human glycome
Q39418711Automatic annotation and visualization tool for mass spectrometry-based glycomics
Q34030882Bioinformatics and molecular modeling in glycobiology.
Q38201351Bioinformatics protocols in glycomics and glycoproteomics.
Q35123584Bioorthogonal chemical reporter methodology for visualization, isolation and analysis of glycoconjugates
Q47725990Biophysical insight into the heparin-peptide interaction and its modulation by a small molecule.
Q37426039Carbohydrate vaccines: developing sweet solutions to sticky situations?
Q37866236Carbohydrate-protein interactions: a 3D view by NMR.
Q33508585Centralized modularity of N-linked glycosylation pathways in mammalian cells
Q39037656Chemical Glycoproteomics
Q36588596Chemical technologies for probing glycans
Q36471241Chemoenzymatic method for glycomics: Isolation, identification, and quantitation
Q37468164Chemoenzymatic synthesis and lectin array characterization of a class of N-glycan clusters.
Q39076583Chemoselective Reactions for the Synthesis of Glycoconjugates from Unprotected Carbohydrates
Q33613575Chiral-auxiliary-mediated 1,2-cis-glycosylations for the solid-supported synthesis of a biologically important branched alpha-glucan
Q44788875Clinical and prognostic implications of β1, 6-N-acetylglucosaminyltransferase V in patients with gastric cancer
Q37711697Clinical significance of polypeptide N-acetylgalactosaminyl transferase-5 (GalNAc-T5) expression in patients with gastric cancer
Q51170076Counting glycans revisited.
Q60497061Cryogenic IR spectroscopy combined with ion mobility spectrometry for the analysis of human milk oligosaccharides
Q35144698Disaccharide binding to galectin-1: free energy calculations and molecular recognition mechanism
Q42787021Disaccharide compositional analysis of heparan sulfate and heparin polysaccharides using UV or high-sensitivity fluorescence (BODIPY) detection.
Q38029137Discovery and design of carbohydrate-based therapeutics
Q34285002Docking server for the identification of heparin binding sites on proteins
Q24648391E-selectin receptors on human leukocytes
Q36453197ELECTRON DETACHMENT DISSOCIATION OF SYNTHETIC HEPARAN SULFATE GLYCOSAMINOGLYCAN TETRASACCHARIDES VARYING IN DEGREE OF SULFATION AND HEXURONIC ACID STEREOCHEMISTRY.
Q34473542Effect of the substituents of the neighboring ring in the conformational equilibrium of iduronate in heparin-like trisaccharides
Q46371345Effects of different oligosaccharides at various dosages on the composition of gut microbiota and short-chain fatty acids in mice with constipation
Q38847934Electrochemical lectin based biosensors as a label-free tool in glycomics.
Q26822552Electrochemistry of nonconjugated proteins and glycoproteins. Toward sensors for biomedicine and glycomics
Q35782646Electron detachment dissociation of fluorescently labeled sialylated oligosaccharides
Q57572212Emerging glycomics technologies
Q34367638Employment of tandem mass spectrometry for the accurate and specific identification of oligosaccharide structures
Q33698046Enhancing glycan isomer separations with metal ions and positive and negative polarity ion mobility spectrometry-mass spectrometry analyses
Q38076635Enzymatic glycosylation of multivalent scaffolds
Q37630490Evaluation of ion mobility-mass spectrometry for determining the isomeric heterogeneity of oligosaccharide-alditols derived from bovine submaxillary mucin
Q33776810Fluorescence-monitored zero dead-volume nanoLC-microESI-QIT-TOF MS for analysis of fluorescently tagged glycosphingolipids
Q34303919Fourier transform mass spectrometry to monitor hyaluronan-protein interactions: use of hydrogen/deuterium amide exchange
Q26830100Fucanomics and galactanomics: marine distribution, medicinal impact, conceptions, and challenges
Q37821306Fucosylation and gastrointestinal cancer
Q34534962Genetic defects in the human glycome
Q38293737Getting to know the extracellular vesicle glycome.
Q37012115Global Identification and Differential Distribution Analysis of Glycans in Subcellular Fractions of Bladder Cells
Q39991378Glucuronic acid can extend O-linked core 1 glycans, but it contributes only weakly to the negative surface charge of Drosophila melanogaster Schneider-2 cells
Q41884743GlyNest and CASPER: two independent approaches to estimate 1H and 13C NMR shifts of glycans available through a common web-interface
Q33686302Glycan Array on Aluminum Oxide-Coated Glass Slides through Phosphonate Chemistry
Q36124193Glycans as receptors for influenza pathogenesis
Q39403495GlycoPep MassList: software to generate massive inclusion lists for glycopeptide analyses
Q30578276Glycobioinformatics: current strategies and tools for data mining in MS-based glycoproteomics
Q49057061Glycome mapping on DNA sequencing equipment
Q35013214Glycomic analysis by glycoprotein immobilization for glycan extraction and liquid chromatography on microfluidic chip
Q34229348Glycomic analysis of glycans released from glycoproteins using chemical immobilization and mass spectrometry
Q37591505Glycomic analysis: an array of technologies.
Q33875839Glycomic and glycoproteomic analysis of glycoproteins-a tutorial.
Q81886862Glycomic profiling of invasive and non-invasive breast cancer cells
Q30437948Glycomics approaches for the bioassay and structural analysis of heparin/heparan sulphates
Q38297633Glycomics of proteoglycan biosynthesis in murine embryonic stem cell differentiation
Q30937269Glycomics profiling of Chinese hamster ovary cell glycosylation mutants reveals N-glycans of a novel size and complexity
Q53401897Glycopolymer brushes for specific lectin binding by controlled multivalent presentation of N-acetyllactosamine glycan oligomers.
Q35033695Glycoproteomic probes for fluorescent imaging of fucosylated glycans in vivo
Q30621928Greedy feature selection for glycan chromatography data with the generalized Dirichlet distribution
Q37095486Harnessing glycomics technologies: integrating structure with function for glycan characterization
Q42201266Heterocyclic boronic acids display sialic acid selective binding in a hypoxic tumor relevant acidic environment
Q35984139High-performance liquid chromatography-mass spectrometry for mapping and sequencing glycosaminoglycan-derived oligosaccharides
Q36766852How to comprehensively analyse proteins and how this influences nutritional research
Q35262822Identification of 34 N-glycan isomers in human serum by capillary electrophoresis coupled with laser-induced fluorescence allows improving glycan biomarker discovery
Q37425396Immunization with Outer Membrane Vesicles Displaying Designer Glycotopes Yields Class-Switched, Glycan-Specific Antibodies
Q36118117Integrated glycoprotein immobilization method for glycopeptide and glycan analysis of cardiac hypertrophy
Q35051146Ion mobility mass spectrometry analysis of isomeric disaccharide precursor, product and cluster ions
Q38288036Localized Chemical Remodeling for Live Cell Imaging of Protein-Specific Glycoform
Q37290930Mammalian glycosylation in immunity
Q37730587Marine glycobiology: current status and future perspectives
Q89621823Metabolomics, a New Promising Technology for Toxicological Research
Q35067297Mice overexpressing β-1,4-Galactosyltransferase I are resistant to TNF-induced inflammation and DSS-induced colitis
Q43484247Multivalent glycoclusters constructed by chiral self-assembly of mannose functionalized perylene bisimide
Q40232772Myelin-associated glycoprotein (MAG) protects neurons from acute toxicity using a ganglioside-dependent mechanism.
Q36917567N-Glycan structure annotation of glycopeptides using a linearized glycan structure database (GlyDB)
Q79369805NMR analysis of carbohydrate-protein interactions
Q38032457Nanoengineered glycan sensors enabling native glycoprofiling for medicinal applications: towards profiling glycoproteins without labeling or liberation steps
Q42366594Native glycan fragments detected by MALDI-FT-ICR mass spectrometry imaging impact gastric cancer biology and patient outcome
Q30489461Noncovalent cell surface engineering: incorporation of bioactive synthetic glycopolymers into cellular membranes
Q35209055Origins of stochasticity and burstiness in high-dimensional biochemical networks
Q58381605Oxime-Based Synthesis of New Chromogenic and Fluorogenic Oligosaccharides
Q58385253Particulate transepithelial drug carriers: barriers and functional polymers
Q38850914Prospects for the therapeutic application of sulfated polysaccharides of brown algae in diseases of the cardiovascular system: review
Q35413473Protein glycosylation in cancer
Q37745062Proteoglycomics: recent progress and future challenges
Q36329430QUANTITY: An Isobaric Tag for Quantitative Glycomics
Q33296230Quantifiable fluorescent glycan microarrays
Q37370214Quantitative glycomics from fluidic glycan microarrays
Q36080170Rapid Screening of Bovine Milk Oligosaccharides in a Whey Permeate Product and Domestic Animal Milks by Accurate Mass Database and Tandem Mass Spectral Library
Q36055373Rapid and sensitive MALDI MS analysis of oligosaccharides by using 2-hydrazinopyrimidine as a derivative reagent and co-matrix
Q37822367Recent advances in the MS analysis of glycoproteins: Capillary and microfluidic workflows
Q37149694Resolving Isomeric Glycopeptide Glycoforms with Hydrophilic Interaction Chromatography (HILIC).
Q33453395Resolving structural isomers of monosaccharide methyl glycosides using drift tube and traveling wave ion mobility mass spectrometry
Q36445568Role and challenges of proteomics in pharma and biotech: technical, scientific and commercial perspective
Q34597839Selective isolation and analysis of glycoprotein fractions and their glycomes from hepatocellular carcinoma sera
Q35064779Serum glycan signatures of gastric cancer.
Q34597523Sharing of worldwide distributed carbohydrate-related digital resources: online connection of the Bacterial Carbohydrate Structure DataBase and GLYCOSCIENCES.de.
Q55689952Single-pot glycoprotein biosynthesis using a cell-free transcription-translation system enriched with glycosylation machinery.
Q26827541Software for automated interpretation of mass spectrometry data from glycans and glycopeptides
Q34615890Storage correction in cells of patients suffering from mucopolysaccharidoses types IIIA and VII after treatment with genistein and other isoflavones
Q37511909Strategies for analysis of the glycosylation of proteins: current status and future perspectives
Q80387200Strategy for the fine characterization of glycosyltransferase specificity using isotopomer assembly
Q35786742Structural Characterization of Carbohydrates by Fourier Transform Tandem Mass Spectrometry
Q46030765Systematic and site-specific analysis of N-sialoglycosylated proteins on the cell surface by integrating click chemistry and MS-based proteomics.
Q35559681Systems glycobiology: biochemical reaction networks regulating glycan structure and function.
Q37332012Targeted glycomics by selected reaction monitoring for highly sensitive glycan compositional analysis
Q30559282The GlycomeAtlas tool for visualizing and querying glycome data
Q90334099The Need for Multi-Omics Biomarker Signatures in Precision Medicine
Q80238171The sweet side of biomarker discovery
Q38232456Therapeutic spectrum of nondigestible oligosaccharides: overview of current state and prospect
Q42571075Ultrasensitive impedimetric lectin biosensors with efficient antifouling properties applied in glycoprofiling of human serum samples
Q30050744UniCarbKB: building a knowledge platform for glycoproteomics
Q41620520pGlyco 2.0 enables precision N-glycoproteomics with comprehensive quality control and one-step mass spectrometry for intact glycopeptide identification

Search more.