Cell cyclins: triggering elements of cancer or not?

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Cell cyclins: triggering elements of cancer or not? is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1009218157
P356DOI10.1186/1477-7819-8-111
P932PMC publication ID3016250
P698PubMed publication ID21176227
P5875ResearchGate publication ID49700487

P2093author name stringMichael Stamatakos
Konstantinos Kontzoglou
Konstantinos Xiromeritis
Ioannis Pateras
Ioannis Alexiou
Ioannis Karaiskos
Victoria Palla
P2860cites workCell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcriptionQ24290273
Cyclin ET, a new splice variant of human cyclin E with a unique expression pattern during cell cycle progression and differentiationQ24544755
Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4Q24644847
Activation of human B-MYB by cyclinsQ24674836
Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)Q24685138
The cyclin D1 proto-oncogene is sequestered in the cytoplasm of mammalian cancer cell linesQ25254998
Cyclin E and survival in patients with breast cancerQ27824788
Cycling to cancer with cyclin D1Q28214862
Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitmentQ28235209
Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathwayQ28237113
Minireview: Cyclin D1: normal and abnormal functionsQ28279069
Chromosomal mapping of the genes for the human cell cycle proteins cyclin C (CCNC), cyclin E (CCNE), p21 (CDKN1) and KAP (CDKN3)Q28298777
Characterization of D-cyclin proteins in hematolymphoid neoplasms: lack of specificity of cyclin-D2 and D3 expression in lymphoma subtypesQ33699243
Anticancer drug targets: cell cycle and checkpoint control.Q33801116
Novel splice variants of cyclin E with altered substrate specificityQ33855990
Tumor-specific proteolytic processing of cyclin E generates hyperactive lower-molecular-weight formsQ33969505
Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family.Q34760368
Cyclin D1 determines mitochondrial function in vivoQ35070938
Cyclin D1, EMS1 and 11q13 amplification in breast cancerQ35130688
Expression of cyclin E and cyclin-dependent kinase 2 correlates with metastasis and prognosis in colorectal carcinoma.Q53395603
Cyclin Dl expression in B-cell non Hodgkin lymphoma.Q53543241
Correlation of cyclin D1 transcript levels, transcript type and protein expression with proliferation and histology among mantle cell lymphomaQ63633957
Conserved structural motifs in cyclins identified by sequence analysisQ67904096
Expression of cyclin E in colorectal adenomas and adenocarcinomas: correlation with expression of Ki-67 antigen and p53 proteinQ71672628
Cyclin E, a potential prognostic marker for breast cancerQ72662855
Expression and amplification of cyclin genes in human breast cancerQ72845253
Expression of cyclin E in human gastric adenomas and adenocarcinomas: correlation with proliferative activity and p53 statusQ73982407
Analysis of cyclin E and CDK2 in ovarian cancer: gene amplification and RNA overexpressionQ74029730
Expression of cell cycle regulators in human cutaneous malignant melanomaQ77919021
Cycling without cyclins.Q35601085
Deletion of 11q23 and cyclin D1 overexpression are frequent aberrations in parathyroid adenomasQ35842080
Initiation of DNA synthesis by human papillomavirus E7 oncoproteins is resistant to p21-mediated inhibition of cyclin E-cdk2 activityQ35888709
Redundant cyclin overexpression and gene amplification in breast cancer cellsQ36090819
Prognostic implications of cell cycle, apoptosis, and angiogenesis biomarkers in non-small cell lung cancer: a reviewQ36147654
Do truncated cyclins contribute to aberrant cyclin expression in cancer?Q36427775
Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expressionQ36759552
Transvection mediated by the translocated cyclin D1 locus in mantle cell lymphomaQ36851904
Low molecular weight cyclin E is specific in breast cancer and is associated with mechanisms of tumor progressionQ37215894
Cancer therapy: targeting cell cycle regulatorsQ37294018
Nuclear cyclin D1: an oncogenic driver in human cancerQ37470373
Cyclin D1/cyclin-dependent kinase 4 interacts with filamin A and affects the migration and invasion potential of breast cancer cellsQ39736048
Cyclin D1 as a universally expressed mantle cell lymphoma-associated tumor antigen for immunotherapyQ39882401
Primary hyperparathyroidism caused by parathyroid-targeted overexpression of cyclin D1 in transgenic mice.Q39946549
Antisense to cyclin D1 inhibits vascular endothelial growth factor-stimulated growth of vascular endothelial cells: implication of tumor vascularizationQ40245226
The low molecular weight cyclin E isoforms augment angiogenesis and metastasis of human melanoma cells in vivo.Q40459704
Cyclin E deregulation alters the biologic properties of ovarian cancer cells.Q40580984
Genetic alterations in human gastrointestinal cancers. The application to molecular diagnosisQ40612363
HIV-1 Tat elongates the G1 phase and indirectly promotes HIV-1 gene expression in cells of glial originQ41045815
Human cytomegalovirus inhibits cellular DNA synthesis and arrests productively infected cells in late G1.Q41163429
Ectopic expression of cyclin D1 prevents activation of gene transcription by myogenic basic helix-loop-helix regulatorsQ41450893
The role of cyclin E in cell proliferation, development and cancerQ41744187
Concurrent amplification of cyclin E and CDK2 genes in colorectal carcinomasQ42804103
The oncogenic activity of cyclin E is not confined to Cdk2 activation alone but relies on several other, distinct functions of the proteinQ42811919
Cyclin D1 expression in typical chronic lymphocytic leukaemiaQ47731697
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P921main subjectcell cycleQ188941
neoplasmQ1216998
Cyclin EQ24724860
Cyclin DQ24781041
cell cycle proteinsQ76598519
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)111
P577publication date2010-12-22
P1433published inWorld Journal of Surgical OncologyQ14520241
P1476titleCell cyclins: triggering elements of cancer or not?
P478volume8

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cites work (P2860)
Q53079443A distinctive ovarian cancer molecular subgroup characterized by poor prognosis and somatic focal copy number amplifications at chromosome 19.
Q38064457Cell cycle-related kinase in carcinogenesis
Q57817291Clinical significance and biological roles of cyclins in gastric cancer
Q34083001Cyclin D3 promotes pancreatic β-cell fitness and viability in a cell cycle-independent manner and is targeted in autoimmune diabetes.
Q35151182Cyclin E involved in early stage carcinogenesis of esophageal adenocarcinoma by SNP DNA microarray and immunohistochemical studies.
Q35843010Deciphering mechanisms of drug sensitivity and resistance to Selective Inhibitor of Nuclear Export (SINE) compounds
Q39206919Effects of cyclin E gene silencing on the proliferation of esophageal cancer cell lines, EC9706, Eca109 and KYSE30.
Q41840776Expression of cyclin D1 and cyclin E in urothelial bladder carcinoma detected in tissue chips using a quantum dot immunofluorescence technique
Q36475933Expression of cyclin E in stage III colorectal carcinoma
Q36823677Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormone
Q35686653High expression of carbonic anhydrase IX is significantly associated with glandular lesions in gastroesophageal junction and with tumorigenesis markers BMI1, MCM4 and MCM7
Q50722957High expression of cyclin A is associated with poor prognosis in endometrial endometrioid adenocarcinoma.
Q37982050Human gene control by vital oncogenes: revisiting a theoretical model and its implications for targeted cancer therapy
Q60912152Immunohistochemical analysis of cyclin A expression in Wilms tumor
Q38994765Implant of polymer containing pentacyclic triterpenes from Eugenia punicifolia inhibits inflammation and activates skeletal muscle remodeling.
Q37584898Killing the second messenger: targeting loss of cell cycle control in endocrine-resistant breast cancer.
Q38287178MK-2206 causes growth suppression and reduces neuroendocrine tumor marker production in medullary thyroid cancer through Akt inhibition.
Q36838387Mitogenic signaling pathways in the liver of growth hormone (GH)-overexpressing mice during the growth period
Q61445018Nonylphenol promotes the proliferation of colorectal cancer COLO205 cells by upregulating the expression of protein kinase C ζ
Q37336665Over-expression of the long non-coding RNA HOTTIP inhibits glioma cell growth by BRE.
Q33782164PAI-1 leads to G1-phase cell-cycle progression through cyclin D3/cdk4/6 upregulation
Q38949849Sterigmatocystin induces G1 arrest in primary human esophageal epithelial cells but induces G2 arrest in immortalized cells: key mechanistic differences in these two models
Q27025081The function and molecular mechnism of cyclin Y protein
Q50752830The prognostic value of cyclin D1 in renal cell carcinoma.
Q38205270The role of the TP73 gene and its transcripts in neuro-oncology
Q36025441Tumor suppressor functions of FBW7 in cancer development and progression

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