Targeted knockout of the Rickettsia rickettsii OmpA surface antigen does not diminish virulence in a mammalian model system

scientific article

Targeted knockout of the Rickettsia rickettsii OmpA surface antigen does not diminish virulence in a mammalian model system is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MBIO.00323-15
P932PMC publication ID4453529
P698PubMed publication ID25827414
P5875ResearchGate publication ID274399646

P50authorTed HackstadtQ38329428
P2093author name stringNicholas F Noriea
Tina R Clark
P2860cites workAnalysis of the Rickettsia africae genome reveals that virulence acquisition in Rickettsia species may be explained by genome reductionQ21093392
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A protective protein antigen of Rickettsia rickettsii has tandemly repeated, near-identical sequencesQ35103198
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rOmpA is a critical protein for the adhesion of Rickettsia rickettsii to host cellsQ74587913
Identification and characterization of epitopes on the 120-kilodalton surface protein antigen of Rickettsia prowazekii with synthetic peptidesQ35484000
Separation of viable Rickettsia typhi from yolk sac and L cell host components by renografin density gradient centrifugationQ35800887
Mariner-based transposon mutagenesis of Rickettsia prowazekiiQ36137161
Genomic comparison of virulent Rickettsia rickettsii Sheila Smith and avirulent Rickettsia rickettsii IowaQ36421473
OmpA-mediated rickettsial adherence to and invasion of human endothelial cells is dependent upon interaction with α2β1 integrinQ36724533
Protective monoclonal antibodies recognize heat-labile epitopes on surface proteins of spotted fever group rickettsiae.Q36999712
Neutralizing activity of monoclonal antibodies to heat-sensitive and heat-resistant epitopes of Rickettsia rickettsii surface proteins.Q37017519
Biochemical and immunochemical analysis of Rickettsia rickettsii strains of various degrees of virulenceQ37084574
A family of clostridial and streptococcal ligand-binding proteins with conserved C-terminal repeat sequencesQ37096019
Reactivity of monoclonal antibodies to Rickettsia rickettsii with spotted fever and typhus group rickettsiaeQ37135146
Plaque assay of rickettsiae in a mammalian cell lineQ37242200
What's new in Rocky Mountain spotted fever?Q37255506
Directed mutagenesis of the Rickettsia prowazekii pld gene encoding phospholipase D.Q37274799
Isolation of species-specific protein antigens of Rickettsia typhi and Rickettsia prowazekii for immunodiagnosis and immunoprophylaxisQ37285832
Antibiotic treatment of rickettsiosis, recent advances and current conceptsQ37291542
Quantifying the forces driving cell-cell adhesion in a fungal pathogen.Q37382369
Rickettsial outer-membrane protein B (rOmpB) mediates bacterial invasion through Ku70 in an actin, c-Cbl, clathrin and caveolin 2-dependent mannerQ37412259
Sequence and expression analysis of the ompA gene of Rickettsia peacockii, an endosymbiont of the Rocky Mountain wood tick, Dermacentor andersoniQ37597477
The realities of biodefense vaccines against RickettsiaQ37616763
Expression and targeting of secreted proteins from Chlamydia trachomatis.Q37713167
Rickettsial evolution in the light of comparative genomicsQ37780582
Tropism and pathogenicity of rickettsiaeQ38022006
Characterization of rickettsial adhesin Adr2 belonging to a new group of adhesins in α-proteobacteriaQ39787138
Distribution of immunogenic epitopes on the two major immunodominant proteins (rOmpA and rOmpB) of Rickettsia conorii among the other rickettsiae of the spotted fever group.Q39811773
Ultrastucture of the surface of Rickettsia prowazeki and Rickettsia akariQ39861543
Evidence for proteolytic cleavage of the 120-kilodalton outer membrane protein of rickettsiae: identification of an avirulent mutant deficient in processingQ40148565
Increased resistance to chloramphenicol in Rickettsia prowazekii with a note on failure to demonstrate genetic interaction amongQ40251753
Identification of two putative rickettsial adhesins by proteomic analysisQ40337996
The major outer membrane protein rOmpB of spotted fever group rickettsiae functions in the rickettsial adherence to and invasion of Vero cellsQ40485479
A novel and naturally occurring transposon, ISRpe1 in the Rickettsia peacockii genome disrupting the rickA gene involved in actin-based motilityQ40498563
Early signaling events involved in the entry of Rickettsia conorii into mammalian cellsQ40525317
Adhesion of outer membrane proteins containing tandem repeats of Anaplasma and Ehrlichia species (Rickettsiales: Anaplasmataceae) to tick cellsQ40575354
Therapeutic delay and mortality in cases of Rocky Mountain spotted feverQ40685757
Determination of antibiotic susceptibility of Rickettsia by the plaque assay techniqueQ40718945
Some Aspects of Rocky Mountain Spotted Fever as Shown by Recent InvestigationsQ40743247
DNA polymorphism in the conserved 190 kDa antigen gene repeat region among spotted fever group RickettsiaeQ40745836
Cloned gene of Rickettsia rickettsii surface antigen: candidate vaccine for Rocky Mountain spotted feverQ40800204
CULTIVATION OF RICKETTSIAE OF THE ROCKY MOUNTAIN SPOTTED FEVER, TYPHUS AND Q FEVER GROUPS IN THE EMBRYONIC TISSUES OF DEVELOPING CHICKS.Q41095129
The citrate synthase-encoding gene of Rickettsia prowazekii is controlled by two promotersQ41294319
The 120 kilodalton outer membrane protein (rOmp B) of Rickettsia rickettsii is encoded by an unusually long open reading frame: evidence for protein processing from a large precursorQ42617349
Differential activity of Rickettsia rickettsii opmA and ompB promoter regions in a heterologous reporter gene system.Q54625114
Molecular Evolution of Rickettsia Surface Antigens: Evidence of Positive SelectionQ57986015
P433issue2
P921main subjectRickettsia rickettsiiQ2698925
P577publication date2015-03-31
P1433published inmBioQ15817061
P1476titleTargeted knockout of the Rickettsia rickettsii OmpA surface antigen does not diminish virulence in a mammalian model system
P478volume6

Reverse relations

cites work (P2860)
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