A retrospective study investigating the rate of HER2 discordance between primary breast carcinoma and locoregional or metastatic disease

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A retrospective study investigating the rate of HER2 discordance between primary breast carcinoma and locoregional or metastatic disease is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1003852953
P356DOI10.1186/1471-2407-12-555
P932PMC publication ID3517741
P698PubMed publication ID23176370
P5875ResearchGate publication ID233766538

P2093author name stringArlene Chan
Belinda Brown
David Ingram
Adrienne Morey
Diana Hastrich
Peter Willsher
P2860cites workClinically used breast cancer markers such as estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 are unstable throughout tumor progression.Q46167485
Serum HER-2/neu conversion to positive at the time of disease progression in patients with breast carcinoma on hormone therapyQ46542698
HER2 protein and gene variation between primary and metastatic breast cancer: significance and impact on patient care.Q54614183
Comparison of HER-2 status between primary breast cancer and corresponding distant metastatic sitesQ59567861
HER2 status in patients with breast carcinoma is not modified selectively by preoperative chemotherapy and is stable during the metastatic processQ74054441
Patterns of her-2/neu amplification and overexpression in primary and metastatic breast cancerQ74299719
Comparison of HER-2 status determined by fluorescence in situ hybridization in primary and metastatic breast carcinomaQ81565196
Comparison of HER2 status between primary tumor and disseminated tumor cells in primary breast cancer patientsQ82907142
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.Q27824766
Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study groupQ27824835
Evaluation of automated silver-enhanced in situ hybridization (SISH) for detection of HER2 gene amplification in breast carcinoma excision and core biopsy specimensQ33407727
Loss of human epidermal growth factor receptor 2 (HER2) expression in metastatic sites of HER2-overexpressing primary breast tumorsQ35808400
HER2 gene status in primary breast cancers and matched distant metastasesQ35906294
Determination of HER2 status using both serum HER2 levels and circulating tumor cells in patients with recurrent breast cancer whose primary tumor was HER2 negative or of unknown HER2 statusQ36458793
Prospective study evaluating the impact of tissue confirmation of metastatic disease in patients with breast cancerQ37240839
Loss of HER2 amplification following trastuzumab-based neoadjuvant systemic therapy and survival outcomesQ37457262
Prognostic impact of discordance between triple-receptor measurements in primary and recurrent breast cancerQ37468681
Quantitative analysis of changes in ER, PR and HER2 expression in primary breast cancer and paired nodal metastases.Q43254569
P407language of work or nameEnglishQ1860
P921main subjectbreast carcinomaQ18555947
P304page(s)555
P577publication date2012-11-24
P1433published inBMC CancerQ326300
P1476titleA retrospective study investigating the rate of HER2 discordance between primary breast carcinoma and locoregional or metastatic disease
P478volume12

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cites work (P2860)
Q49796316Breast cancer subtype discordance: impact on post-recurrence survival and potential treatment options.
Q41932946Discordance rate of HER2 status in primary breast carcinomas versus synchronous axillary lymph node metastases: a multicenter retrospective investigation
Q34834419Discordance rate of HER2 status in primary gastric carcinomas and synchronous lymph node metastases: a multicenter retrospective analysis
Q41812451Expression of human epidermal growth factor receptor 2 in primary and paired parenchymal recurrent and/or metastatic sites of gastric cancer
Q26780318HER2 Status in Premalignant, Early, and Advanced Neoplastic Lesions of the Stomach
Q38810954Molecular Concordance Between Primary Breast Cancer and Matched Metastases.
Q89661763Plasma HER2ECD a promising test for patient prognosis and prediction of response in HER2 positive breast cancer: results of a randomized study - SAKK 22/99
Q50120368Receptor Conversion in Distant Breast Cancer Metastases: A Systematic Review and Meta-analysis
Q40409180St Gallen molecular subtypes in feline mammary carcinoma and paired metastases-disease progression and clinical implications from a 3-year follow-up study.

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