| scholarly article | Q13442814 |
| P50 | author | Irwin McLean | Q17488812 |
| Richard B. Presland | Q38804618 | ||
| Alan D. Irvine | Q39066910 | ||
| John Digiovanna | Q88063055 | ||
| Sue Lewis-Jones | Q114415625 | ||
| Aileen Sandilands | Q117242009 | ||
| Gráinne M O'Regan | Q117242012 | ||
| Haihui Liao | Q117242014 | ||
| David R Goudie | Q117242018 | ||
| Ana Terron-Kwiatkowski | Q117242024 | ||
| Sherri J Bale | Q117242026 | ||
| Philip Fleckman | Q117242029 | ||
| Gehan Arseculeratne | Q117242030 | ||
| Ann Sergeant | Q117242032 | ||
| P2093 | author name string | Frances J D Smith | |
| Alan T Evans | |||
| Yiwei Zhao | |||
| Linda E Campbell | |||
| John G Compton | |||
| Colin S Munro | |||
| P2860 | cites work | Profilaggrin is a major epidermal calcium-binding protein | Q28118351 |
| Netherton syndrome: disease expression and spectrum of SPINK5 mutations in 21 families | Q28200896 | ||
| Functional analysis of the profilaggrin N-terminal peptide: identification of domains that regulate nuclear and cytoplasmic distribution | Q28572970 | ||
| Characterization of a class of cationic proteins that specifically interact with intermediate filaments | Q28592555 | ||
| Mutations in the rod 1A domain of keratins 1 and 10 in bullous congenital ichthyosiform erythroderma (BCIE). | Q34290979 | ||
| Genomic organization and fine mapping of the keratin 2e gene (KRT2E): K2e V1 domain polymorphism and novel mutations in ichthyosis bullosa of Siemens | Q34478659 | ||
| The cornified envelope: a model of cell death in the skin | Q36085605 | ||
| Filaggrin: a keratin filament associated protein | Q38156833 | ||
| Keratinocytes cultured from subjects with ichthyosis vulgaris are phenotypically abnormal | Q41906834 | ||
| Characterization of the mouse loricrin gene: linkage with profilaggrin and the flaky tail and soft coat mutant loci on chromosome 3. | Q42688900 | ||
| Reduced stability and bi-allelic, coequal expression of profilaggrin mRNA in keratinocytes cultured from subjects with ichthyosis vulgaris | Q47993940 | ||
| Organization, structure, and polymorphisms of the human profilaggrin gene | Q68616823 | ||
| Ichthyosis vulgaris: identification of a defect in synthesis of filaggrin correlated with an absence of keratohyaline granules | Q69381252 | ||
| Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex ("epidermal differentiation complex") on human chromosome 1q21 | Q71049670 | ||
| Genetic heterogeneity in lamellar ichthyosis | Q71384383 | ||
| Evidence for specific proteolytic cleavage of the N-terminal domain of human profilaggrin during epidermal differentiation | Q73012075 | ||
| Loss of normal profilaggrin and filaggrin in flaky tail (ft/ft) mice: an animal model for the filaggrin-deficient skin disease ichthyosis vulgaris | Q73307513 | ||
| Linkage analysis suggests a locus of ichthyosis vulgaris on 1q22 | Q73601400 | ||
| Differential patterns of filaggrin expression in lamellar ichthyosis | Q78173463 | ||
| Mapping of the associated phenotype of an absent granular layer in ichthyosis vulgaris to the epidermal differentiation complex on chromosome 1 | Q78631426 | ||
| Keratin bundling proteins | Q81261883 | ||
| Clinical Features of Autosomal Dominant and Sex-linked Ichthyosis in an English Population | Q84950325 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 337-342 | |
| P577 | publication date | 2006-01-29 | |
| P1433 | published in | Nature Genetics | Q976454 |
| P1476 | title | Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris | |
| P478 | volume | 38 |
| Q37137538 | "Outside-to-inside" (and now back to "outside") pathogenic mechanisms in atopic dermatitis. |
| Q28585387 | 12R-lipoxygenase deficiency disrupts epidermal barrier function |
| Q35385758 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin increases the expression of genes in the human epidermal differentiation complex and accelerates epidermal barrier formation |
| Q33730154 | 3D In vitro model of a functional epidermal permeability barrier from human embryonic stem cells and induced pluripotent stem cells |
| Q49152959 | 8th Georg Rajka International Symposium on Atopic Dermatitis: meeting report. |
| Q56996876 | A Prospective Study of Filaggrin Null Mutations in Keratoconus Patients with or without Atopic Disorders |
| Q50852813 | A case of junctional epidermolysis bullosa with prurigo-like lesions and reduction of collagen XVII and filaggrin. |
| Q47162944 | A curated gene list for reporting results of newborn genomic sequencing. |
| Q36294118 | A de novo variant in the ASPRV1 gene in a dog with ichthyosis. |
| Q35230158 | A generalizable hypothesis for the genetic architecture of disease: pleomorphic risk loci |
| Q37286978 | A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis |
| Q33858072 | A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming. |
| Q36359407 | A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. |
| Q59755350 | A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic d |
| Q33755831 | A milieu of regulatory elements in the epidermal differentiation complex syntenic block: implications for atopic dermatitis and psoriasis |
| Q35764953 | A novel filaggrin gene mutation 7487delC in an Indonesian (Javanese) patient with atopic dermatitis. |
| Q35319834 | A possible association between a dysfunctional skin barrier (filaggrin null-mutation status) and diabetes: a cross-sectional study |
| Q24602843 | A single-nucleotide deletion in the POMP 5' UTR causes a transcriptional switch and altered epidermal proteasome distribution in KLICK genodermatosis |
| Q58782221 | Adhesion of Staphylococcus aureus to Corneocytes from Atopic Dermatitis Patients Is Controlled by Natural Moisturizing Factor Levels |
| Q94561512 | Advances in the Immunology and Genetics of Leprosy |
| Q42567150 | Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development. |
| Q34204432 | Allergic asthma: influence of genetic and environmental factors |
| Q46421916 | Alterations in Epidermal Eicosanoid Metabolism Contribute to Inflammation and Impaired Late Differentiation in FLG-Mutated Atopic Dermatitis |
| Q37010110 | Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero |
| Q36989842 | An Analysis of the Filaggrin Gene Polymorphism in Korean Atopic Dermatitis Patients. |
| Q42625730 | An association study of 22 candidate genes in psoriasis families reveals shared genetic factors with other autoimmune and skin disorders |
| Q39685927 | An intronic enhancer driven by NF-κB contributes to transcriptional regulation of peptidylarginine deiminase type I gene in human keratinocytes. |
| Q28468651 | An update of the defensive barrier function of skin |
| Q33868032 | An update on the genetics of atopic dermatitis: scratching the surface in 2009. |
| Q45376101 | Analyses of FLG mutation frequency and filaggrin expression in isolated ichthyosis vulgaris (IV) and atopic dermatitis-associated IV. |
| Q50065611 | Array-based sequencing of filaggrin gene for comprehensive detection of disease-associated variants. |
| Q64234829 | Assessing the Pathogenicity, Penetrance, and Expressivity of Putative Disease-Causing Variants in a Population Setting |
| Q86499120 | Assessing the in vivo epidermal barrier in mice: dye penetration assays |
| Q47251720 | Association of FLG single nucleotide variations with clinical phenotypes of atopic dermatitis. |
| Q35588826 | Association of common filaggrin null mutations with atopy but not chronic rhinosinusitis. |
| Q40572072 | Association of single nucleotide polymorphism rs2065955 of the filaggrin gene with susceptibility to Epstein-Barr virus-associated gastric carcinoma and EBV-negative gastric carcinoma |
| Q43861409 | Association of skin barrier genes within the PSORS4 locus is enriched in Singaporean Chinese with early-onset psoriasis |
| Q37698783 | Associations of filaggrin gene loss-of-function variants with urinary phthalate metabolites and testicular function in young Danish Men. |
| Q39599395 | Atopic Dermatitis Susceptibility Variants in Filaggrin Hitchhike Hornerin Selective Sweep. |
| Q50448143 | Atopic Eczema: Genetic Associations and Potential Links to Developmental Exposures. |
| Q98186349 | Atopic dermatitis |
| Q37549998 | Atopic dermatitis and disease severity are the main risk factors for food sensitization in exclusively breastfed infants |
| Q37937455 | Atopic dermatitis and the atopic march: what is new? |
| Q34625597 | Atopic dermatitis in children: clinical features, pathophysiology, and treatment |
| Q87204871 | Atopic eczema |
| Q41904665 | Barrier function and microbiotic dysbiosis in atopic dermatitis |
| Q37037943 | Barrier repair trumps immunology in the pathogenesis and therapy of atopic dermatitis |
| Q37105441 | Basis for the barrier abnormality in atopic dermatitis: outside-inside-outside pathogenic mechanisms |
| Q50229784 | Best practices, new perspectives and the perfect emollient: optimizing the management of contact dermatitis. |
| Q33459162 | Carrier status for the common R501X and 2282del4 filaggrin mutations is not associated with hearing phenotypes in 5,377 children from the ALSPAC cohort. |
| Q50736596 | Carriers of filaggrin gene (FLG) mutations avoid professional exposure to irritants in adulthood. |
| Q49057616 | Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin. |
| Q34579689 | Caspase-14 protects against epidermal UVB photodamage and water loss |
| Q34746129 | Caspase-14 reveals its secrets |
| Q37499326 | Cellular and molecular mechanisms in atopic dermatitis |
| Q47223383 | Characterization of Water Self-Diffusion in Human Stratum Corneum |
| Q37164077 | Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges |
| Q55056966 | Characterization of canine filaggrin: gene structure and protein expression in dog skin. |
| Q34571051 | Chromosome 11q13.5 variant associated with childhood eczema: an effect supplementary to filaggrin mutations |
| Q57299708 | Clinical Features and Diagnostic Criteria of Atopic Dermatitis |
| Q58859768 | Clinical Severity Correlates with Impaired Barrier in Filaggrin-Related Eczema |
| Q34481975 | Clinical presentation of atopic dermatitis by filaggrin gene mutation status during the first 7 years of life in a prospective cohort study |
| Q34324282 | Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis |
| Q33837769 | Coherent somatic mutation in autoimmune disease |
| Q34477814 | Common FLG mutation K4671X not associated with atopic dermatitis in Han Chinese in a family association study |
| Q41669695 | Common filaggrin gene mutations and risk of cervical cancer. |
| Q28303063 | Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis |
| Q35622634 | Comparative genomics reveals conservation of filaggrin and loss of caspase-14 in dolphins |
| Q43564093 | Complete filaggrin deficiency in ichthyosis vulgaris is associated with only moderate changes in epidermal permeability barrier function profile |
| Q57061506 | Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema |
| Q48089989 | Concurrent Chondrodysplasia Punctata Type 2 (Conradi-Hunermann-Happle Syndrome) and Ichthyosis Vulgaris in Teenaged Twin Girls. |
| Q55082683 | Congenital ichthyosis patient with squamous cell carcinoma of the skin who received concurrent chemoradiation: A case report. |
| Q36907593 | Control of somatic tissue differentiation by the long non-coding RNA TINCR. |
| Q38788790 | Control of the Physical and Antimicrobial Skin Barrier by an IL-31-IL-1 Signaling Network. |
| Q42935186 | Coordinate interaction between IL-13 and epithelial differentiation cluster genes in eosinophilic esophagitis. |
| Q43737889 | Copy-number variation of the filaggrin gene in Korean patients with atopic dermatitis: what really matters, 'number' or 'variation'? |
| Q89747842 | Correlation of age-of-onset of Atopic Dermatitis with Filaggrin loss-of-function variant status |
| Q35738525 | Crystal Structure of Human Profilaggrin S100 Domain and Identification of Target Proteins Annexin II, Stratifin, and HSP27. |
| Q41823296 | Current Understanding in Pathogenesis of Atopic Dermatitis |
| Q37038468 | Current aspects of innate and adaptive immunity in atopic dermatitis |
| Q38076304 | Cysteine proteases: mode of action and role in epidermal differentiation |
| Q35633397 | Cytokine profiles in interstitial fluid from chronic atopic dermatitis skin. |
| Q35759101 | Deconstructing the skin: cytoarchitectural determinants of epidermal morphogenesis |
| Q24317035 | Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin |
| Q43181179 | Deimination is regulated at multiple levels including auto-deimination of peptidylarginine deiminases. |
| Q28118423 | Deimination of human filaggrin-2 promotes its proteolysis by calpain 1 |
| Q44662108 | Deletion of Late Cornified Envelope 3B and 3C genes is not associated with atopic dermatitis. |
| Q46175556 | Development of an ichthyosiform phenotype in Alox12b-deficient mouse skin transplants |
| Q37095239 | Discovering susceptibility genes for asthma and allergy |
| Q38237121 | Discovery in genetic skin disease: the impact of high throughput genetic technologies |
| Q58859701 | Disorders of Keratinization |
| Q36809911 | Disorders of keratinisation: from rare to common genetic diseases of skin and other epithelial tissues. |
| Q28590539 | Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice |
| Q37526675 | Does eczema lead to asthma? |
| Q92489299 | EMSY expression affects multiple components of the skin barrier with relevance to atopic dermatitis |
| Q37390367 | Eczema genetics: current state of knowledge and future goals |
| Q37782462 | Eczema in early life: genetics, the skin barrier, and lessons learned from birth cohort studies |
| Q36770778 | Effect of filaggrin breakdown products on growth of and protein expression by Staphylococcus aureus |
| Q93088740 | Effect of filaggrin loss-of-function mutations on atopic dermatitis in young age: a longitudinal birth cohort study |
| Q24300787 | Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing |
| Q41524591 | Embryonic AP1 Transcription Factor Deficiency Causes a Collodion Baby-Like Phenotype |
| Q36023872 | Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge |
| Q42409257 | Epidermal Differentiation in Barrier Maintenance and Wound Healing |
| Q38265975 | Epidermal barrier disorders and corneodesmosome defects |
| Q37980290 | Epidermal barrier dysfunction and cutaneous sensitization in atopic diseases |
| Q37507508 | Epidermal barrier dysfunction in atopic dermatitis. |
| Q34576611 | Epidermal barrier formation and recovery in skin disorders |
| Q38201396 | Epidermal barriers |
| Q37776585 | Evolution of Conventional Therapy in Atopic Dermatitis |
| Q38268891 | Evolving concepts of neonatal skin |
| Q90318837 | Exacerbation of ichthyosis vulgaris phenotype by co-inheritance of STS and FLG mutations in a Chinese family with ichthyosis: a case report |
| Q53290464 | Explant cultures of atopic dermatitis biopsies maintain their epidermal characteristics in vitro. |
| Q36239426 | Exploring the origins of asthma: Lessons from twin studies |
| Q41911944 | Expression of filaggrin in normal and keratinized conjunctiva |
| Q39637500 | Expression of wild-type, but not mutant, loricrin causes programmed cell death in HaCaT keratinocytes |
| Q38091743 | Filaggrin - revisited |
| Q61159491 | Filaggrin Is a Predominant Member of the Denaturation-Resistant Nickel-Binding Proteome of Human Epidermis |
| Q37622167 | Filaggrin Mutation in Korean Patients with Atopic Dermatitis. |
| Q92928120 | Filaggrin and atopic march |
| Q37138571 | Filaggrin and the great epidermal barrier grief |
| Q47775075 | Filaggrin compound heterozygous patients carry mutations in trans position. |
| Q30494794 | Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens |
| Q28079701 | Filaggrin failure - from ichthyosis vulgaris to atopic eczema and beyond |
| Q37272219 | Filaggrin gene defects and risk of developing allergic sensitisation and allergic disorders: systematic review and meta-analysis |
| Q33834147 | Filaggrin gene defects are independent risk factors for atopic asthma in a Polish population: a study in ECAP cohort |
| Q33655186 | Filaggrin gene mutation c.3321delA is associated with various clinical features of atopic dermatitis in the Chinese Han population |
| Q42404524 | Filaggrin gene mutations and new SNPs in asthmatic patients: a cross-sectional study in a Spanish population. |
| Q40222215 | Filaggrin gene polymorphism associated with Epstein-Barr virus-associated tumors in China. |
| Q40289819 | Filaggrin genotype and skin diseases independent of atopic dermatitis in childhood. |
| Q34099095 | Filaggrin genotype determines functional and molecular alterations in skin of patients with atopic dermatitis and ichthyosis vulgaris |
| Q42919021 | Filaggrin genotype does not determine the skin's threshold to UV-induced erythema |
| Q34838614 | Filaggrin genotype in ichthyosis vulgaris predicts abnormalities in epidermal structure and function |
| Q33903373 | Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 school children. |
| Q48248501 | Filaggrin has evolved from an "S100 fused-type protein" (SFTP) gene present in a common ancestor of amphibians and mammals |
| Q28242202 | Filaggrin in the frontline: role in skin barrier function and disease |
| Q36916564 | Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase |
| Q57401969 | Filaggrin loss-of-function mutation R501X and 2282del4 carrier status is associated with fissured skin on the hands: results from a cross-sectional population study |
| Q37126645 | Filaggrin loss-of-function mutations and association with allergic diseases |
| Q34294641 | Filaggrin loss-of-function mutations are associated with food allergy in childhood and adolescence |
| Q47901863 | Filaggrin loss-of-function variants are associated with atopic comorbidity in pediatric inflammatory bowel disease |
| Q37979847 | Filaggrin mutations and atopy: consequences for future therapeutics |
| Q57636998 | Filaggrin mutations p.R501X and c.2282del4 in ichthyosis vulgaris |
| Q57638194 | Filaggrin null alleles are not associated with hand eczema or contact allergy |
| Q57316218 | Filaggrin null mutations and childhood atopic eczema: A population-based case-control study |
| Q81390404 | Filaggrin null mutations are associated with atopic dermatitis and elevated levels of IgE in the Japanese population: a family and case-control study |
| Q34981540 | Filaggrin null mutations are not a protective factor for acne vulgaris. |
| Q37619379 | Filaggrin-2 variation is associated with more persistent atopic dermatitis in African American subjects |
| Q33915290 | Filaggrin-deficient mice exhibit TH17-dominated skin inflammation and permissiveness to epicutaneous sensitization with protein antigen |
| Q33650573 | Filaggrin-null mutations are associated with increased maturation markers on Langerhans cells. |
| Q81533595 | Filaggrin: an emerging star in atopic march |
| Q35855529 | Focal adhesion kinase controls pH-dependent epidermal barrier homeostasis by regulating actin-directed Na+/H+ exchanger 1 plasma membrane localization |
| Q58923901 | Full Sequencing of the FLG Gene in Italian Patients with Atopic Eczema: Evidence of New Mutations, but Lack of an Association |
| Q42648107 | Gene (mRNA) expression in canine atopic dermatitis: microarray analysis |
| Q21090137 | Gene-environment interaction in the onset of eczema in infancy: filaggrin loss-of-function mutations enhanced by neonatal cat exposure |
| Q37016579 | Genetic Association Analysis Reveals Differences in the Contribution of NOD2 Variants to the Clinical Phenotypes of Orofacial Granulomatosis. |
| Q42089233 | Genetic Polymorphism of FLG in Korean Ichthyosis Vulgaris Patients |
| Q35085864 | Genetic dissection of eosinophilic esophagitis provides insight into disease pathogenesis and treatment strategies |
| Q34342451 | Genetic polymorphisms and associated susceptibility to asthma |
| Q26777925 | Genetics of asthma: an introduction for the clinician |
| Q44066217 | Genetics of common chronic inflammatory skin diseases : An update on atopic dermatitis and psoriasis |
| Q34720303 | Genome-wide analysis in German shepherd dogs reveals association of a locus on CFA 27 with atopic dermatitis |
| Q84743938 | Genome-wide association analysis of canine atopic dermatitis and identification of disease related SNPs |
| Q38060839 | HTLV-1-associated infective dermatitis: updates on the pathogenesis |
| Q37835969 | Harnessing dendritic cells in inflammatory skin diseases. |
| Q46845493 | Hepoxilin A3 (HXA3) synthase deficiency is causative of a novel ichthyosis form |
| Q38348536 | Hereditary barrier-related diseases involving the tight junction: lessons from skin and intestine |
| Q34312026 | Heritable filaggrin disorders: the paradigm of atopic dermatitis |
| Q57638950 | Heterozygous Null Alleles in Filaggrin Contribute to Clinical Dry Skin in Young Adults and the Elderly |
| Q55012365 | High frequency of primary hereditary ichthyoses in the North-East region of Cairo, Egypt. |
| Q82668161 | Highly complex peptide aggregates of the S100 fused-type protein hornerin are present in human skin |
| Q61632990 | Human hyper-IgE syndrome: singular or plural? |
| Q43458778 | Human β-defensin-2 as a marker for disease severity and skin barrier properties in atopic dermatitis. |
| Q43094946 | Hypoxia-inducible factors regulate filaggrin expression and epidermal barrier function |
| Q88872584 | Ichthyosis molecular fingerprinting shows profound TH17 skewing and a unique barrier genomic signature |
| Q37045238 | Ichthyosis update: towards a function-driven model of pathogenesis of the disorders of cornification and the role of corneocyte proteins in these disorders |
| Q38072741 | Ichthyosis vulgaris: the filaggrin mutation disease. |
| Q24321438 | Ichthyosis, follicular atrophoderma, and hypotrichosis caused by mutations in ST14 is associated with impaired profilaggrin processing |
| Q37721725 | Identification and comparative analysis of the epidermal differentiation complex in snakes |
| Q48057938 | Identification of trichohyalin-like 1, an s100 fused-type protein selectively expressed in hair follicles. |
| Q57244453 | Impact of filaggrin mutations on Raman spectra and biophysical properties of the stratum corneum in mild to moderate atopic dermatitis |
| Q41865099 | In vivo gene silencing following non-invasive siRNA delivery into the skin using a novel topical formulation |
| Q48055869 | Inherited Nonsyndromic Ichthyoses: An Update on Pathophysiology, Diagnosis and Treatment |
| Q36543023 | Inherited ichthyoses/generalized Mendelian disorders of cornification |
| Q38761867 | Inherited ichthyosis: Non-syndromic forms |
| Q79460774 | Inhibition of histone deacetylation promotes abnormal epidermal differentiation and specifically suppresses the expression of the late differentiation marker profilaggrin |
| Q37823415 | Innate immunity in atopic dermatitis |
| Q30104783 | Interaction of bovine erythrocyte superoxide dismutase with hydrogen peroxide. Inactivation of the enzyme |
| Q24194413 | Interventions for congenital ichthyosis |
| Q35609038 | Intragenic copy number variation within filaggrin contributes to the risk of atopic dermatitis with a dose-dependent effect |
| Q37915762 | Is the skin barrier abnormal in dogs with atopic dermatitis? |
| Q37273142 | Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome |
| Q43072814 | Knockdown of filaggrin impairs diffusion barrier function and increases UV sensitivity in a human skin model |
| Q45253506 | Lack of association between filaggrin gene mutations and onset of psoriasis in childhood. |
| Q39094595 | Lessons from Animal Models of Cytoplasmic Intermediate Filament Proteins |
| Q37139810 | Lipids and skin barrier function--a clinical perspective |
| Q79434766 | Looking ahead by looking back |
| Q82622841 | Looking ahead in dermatology: skin and allergy |
| Q90694778 | Loricrin: Past, Present, and Future |
| Q24294533 | Loss of corneodesmosin leads to severe skin barrier defect, pruritus, and atopy: unraveling the peeling skin disease |
| Q41084067 | Loss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype |
| Q58859832 | Loss-of-Function Mutations in the Filaggrin Gene Lead to Reduced Level of Natural Moisturizing Factor in the Stratum Corneum |
| Q61410976 | Loss-of-Function Mutations in the Gene Encoding Filaggrin Are Not Strongly Associated with Chronic Actinic Dermatitis |
| Q59498898 | Loss-of-Function Variants of the Filaggrin Gene Are Not Major Susceptibility Factors for Psoriasis Vulgaris or Psoriatic Arthritis in German Patients |
| Q48051410 | Loss-of-function mutations in filaggrin gene associate with psoriasis vulgaris in Chinese population |
| Q45245735 | Lower prevalence of common filaggrin mutations in a community sample of atopic eczema: is disease severity important? |
| Q37868636 | Malignant skin tumours in patients with inherited ichthyosis |
| Q38079280 | Management of ichthyosis and related conditions gene-based diagnosis and emerging gene-based therapy |
| Q35165436 | Maternal filaggrin mutations increase the risk of atopic dermatitis in children: an effect independent of mutation inheritance |
| Q35097182 | Matriptase deletion initiates a Sjögren's syndrome-like disease in mice |
| Q24609336 | Matriptase initiates activation of epidermal pro-kallikrein and disease onset in a mouse model of Netherton syndrome |
| Q34809525 | Matriptase: potent proteolysis on the cell surface |
| Q36639122 | Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrier |
| Q55411644 | Microbiome in the Gut-Skin Axis in Atopic Dermatitis. |
| Q52585412 | Mite and cockroach allergens activate protease-activated receptor 2 and delay epidermal permeability barrier recovery. |
| Q54453221 | Moisturizing treatment of patients with atopic dermatitis and ichthyosis vulgaris improves dry skin, but has a modest effect on gene expression regardless of FLG genotype. |
| Q38203185 | Molecular biology of atopic dermatitis |
| Q82617890 | Molecular genetics of the skin: the implications of understanding |
| Q24318288 | Molecular identification and expression analysis of filaggrin-2, a member of the S100 fused-type protein family |
| Q38962158 | Molecular mechanisms in atopic eczema: insights gained from genetic studies |
| Q89529714 | Multifaceted Analyses of Epidermal Serine Protease Activity in Patients with Atopic Dermatitis |
| Q47037332 | Multiplex epithelium dysfunction due to CLDN10 mutation: the HELIX syndrome. |
| Q30827918 | Natural Selection in the Great Apes |
| Q37893540 | Nickel allergies: paying the Toll for innate immunity |
| Q39670897 | Noninvasive detection of filaggrin gene mutations using Raman spectroscopy |
| Q44971096 | Novel filaggrin mutation but no other loss-of-function variants found in Ethiopian patients with atopic dermatitis. |
| Q47928659 | Of flaky tails and itchy skin |
| Q36580486 | Old King coal - molecular mechanisms underlying an ancient treatment for atopic eczema |
| Q38767340 | On the phenotypic spectrum of serine biosynthesis defects |
| Q36851187 | On the role of the epidermal differentiation complex in ichthyosis vulgaris, atopic dermatitis and psoriasis |
| Q36043328 | One remarkable molecule: filaggrin. |
| Q39621704 | Optimization of filaggrin expression and processing in cultured rat keratinocytes. |
| Q42041706 | Overcoming the Barrier Treatment of Ichthyosis: A Combination-therapy Approach |
| Q41661456 | Overexpression of constitutively active BMP-receptor-IB in mouse skin causes an ichthyosis-vulgaris-like disease. |
| Q64097094 | PEBBLES study protocol: a randomised controlled trial to prevent atopic dermatitis, food allergy and sensitisation in infants with a family history of allergic disease using a skin barrier improvement strategy |
| Q83350797 | PSORS1: linking genetics and immunology |
| Q51902117 | Par2 inactivation inhibits early production of TSLP, but not cutaneous inflammation, in Netherton syndrome adult mouse model. |
| Q27348706 | Periodic Exposure of Keratinocytes to Cold Physical Plasma: An In Vitro Model for Redox-Related Diseases of the Skin. |
| Q35846994 | Pooled Sequencing of Candidate Genes Implicates Rare Variants in the Development of Asthma Following Severe RSV Bronchiolitis in Infancy |
| Q56112407 | Possibilities for human skin characterization based on strongly reduced Raman spectroscopic information |
| Q57638948 | Prevalent and Rare Mutations in the Gene Encoding Filaggrin in Japanese Patients with Ichthyosis Vulgaris and Atopic Dermatitis |
| Q52651330 | Primary atopic disorders. |
| Q47338748 | Profilaggrin, dry skin, and atopic dermatitis risk: size matters. |
| Q84569535 | Protein kinase C/mitogen-activated protein kinase signaling in keratinocyte differentiation control |
| Q24201204 | Psychological and educational interventions for atopic eczema in children |
| Q36770783 | Raman profiles of the stratum corneum define 3 filaggrin genotype-determined atopic dermatitis endophenotypes |
| Q36462660 | Recent advances in asthma genetics |
| Q26740640 | Recent advances in understanding ichthyosis pathogenesis |
| Q61460045 | Recent evolution of the human skin barrier |
| Q45169364 | Recombinant filaggrin is internalized and processed to correct filaggrin deficiency |
| Q64259313 | Reconstructed Skin Models Revealed Unexpected Differences in Epidermal African and Caucasian Skin |
| Q34089304 | Redox imbalance in T cell-mediated skin diseases |
| Q52645660 | Reevaluation of the non-lesional dry skin in atopic dermatitis by acute barrier disruption: an abnormal permeability barrier homeostasis with defective processing to generate ceramide. |
| Q33955235 | Regulation of the dynamic chromatin architecture of the epidermal differentiation complex is mediated by a c-Jun/AP-1-modulated enhancer |
| Q84203584 | Regulatory role for the profilaggrin N-terminal domain in epidermal homeostasis |
| Q37009417 | Reliability and validity of genotyping filaggrin null mutations. |
| Q36038743 | SASPase regulates stratum corneum hydration through profilaggrin-to-filaggrin processing |
| Q84554389 | SNPing at the Epidermal Barrier |
| Q46222098 | Second report of FLG R501X mutation in Japanese patients with atopic dermatitis |
| Q44448070 | Semidominant inheritance in epidermolytic ichthyosis |
| Q50907995 | Sensitization via healthy skin programs Th2 responses in individuals with atopic dermatitis. |
| Q36201956 | Sequence heuristics to encode phase behaviour in intrinsically disordered protein polymers |
| Q36292214 | Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin |
| Q43995981 | Severe skin inflammation and filaggrin mutation similarly alter the skin barrier in patients with atopic dermatitis |
| Q52373773 | Single blinded, randomized, placebo-controlled study on the effects of ciclosporin on cutaneous barrier function and immunological response in atopic beagles. |
| Q33300613 | Single nucleotide polymorphism-based genome-wide linkage analysis in Japanese atopic dermatitis families |
| Q30405464 | Skin barrier defects in atopic dermatitis |
| Q35757285 | Skin barrier disruption: a requirement for allergen sensitization? |
| Q82996787 | Skin barrier function and allergic risk |
| Q37986899 | Skin biology |
| Q35541738 | Skin reaction and regeneration after single sodium lauryl sulfate exposure stratified by filaggrin genotype and atopic dermatitis phenotype. |
| Q42859520 | Spontaneous atopic dermatitis-like symptoms in a/a ma ft/ma ft/J flaky tail mice appear early after birth |
| Q37405807 | Staphylococcus aureus Exploits Epidermal Barrier Defects in Atopic Dermatitis to Trigger Cytokine Expression |
| Q35972819 | Storage Temperature Alters the Expression of Differentiation-Related Genes in Cultured Oral Keratinocytes |
| Q24615302 | Stratum corneum dysfunction in dandruff |
| Q44859320 | Stratum corneum removal facilitates experimental sensitization to mite allergens in atopic dogs |
| Q36246584 | Structure and evolution of the filaggrin gene repeated region in primates |
| Q36297443 | Study protocol to investigate the environmental and genetic aetiology of atopic dermatitis: the Indonesian Prospective Study of Atopic Dermatitis in Infants (ISADI). |
| Q51002480 | Substrate elasticity as biomechanical modulator of tissue homeostatic parameters in corneal keratinocytes. |
| Q35823094 | Suppression of Tumorigenicity-14, encoding matriptase, is a critical suppressor of colitis and colitis-associated colon carcinogenesis |
| Q36823123 | Susceptibility to asthma and eczema from mucosal and epidermal expression of distinctive genes |
| Q59403414 | TCF/Lef1-Mediated Control of Lipid Metabolism Regulates Skin Barrier Function |
| Q48278334 | Targeted next-generation sequencing identifies nine novel filaggrin gene variants in Chinese Han patients with ichthyosis vulgaris. |
| Q34556081 | The Atopic March: Progression from Atopic Dermatitis to Allergic Rhinitis and Asthma |
| Q33773413 | The Jekyll and Hyde functions of caspases |
| Q38730103 | The Molecular Revolution in Cutaneous Biology: EDC and Locus Control. |
| Q34589244 | The allergy gene: how a mutation in a skin protein revealed a link between eczema and asthma |
| Q38704374 | The atopic march: current insights into skin barrier dysfunction and epithelial cell-derived cytokines. |
| Q51582462 | The atopic march: progression from atopic dermatitis to allergic rhinitis and asthma. |
| Q37406971 | The biology of cystatin M/E and its cognate target proteases. |
| Q51939172 | The development of core learning outcomes relevant to clinical practice: identifying priority areas for genetics education for non-genetics specialist registrars. |
| Q34355367 | The genetics of human skin disease |
| Q40181403 | The global state of psoriasis disease epidemiology: a workshop report |
| Q34645453 | The hepoxilin connection in the epidermis |
| Q28264599 | The human epidermal differentiation complex: cornified envelope precursors, S100 proteins and the 'fused genes' family |
| Q34556543 | The ichthyoses. Pathophysiological models of epidermal differentiation |
| Q34032522 | The infectious aspects of atopic dermatitis |
| Q37986624 | The matriptase-prostasin proteolytic cascade in epithelial development and pathology |
| Q36291414 | The persistence of atopic dermatitis and filaggrin (FLG) mutations in a US longitudinal cohort |
| Q36946174 | The prevalence of mutations in the gene encoding filaggrin in the population of Polish patients with atopic dermatitis |
| Q90503142 | The role of the skin microbiome in atopic dermatitis |
| Q38075148 | The stratum corneum: the rampart of the mammalian body |
| Q92708306 | Three rare disease diagnoses in one patient through exome sequencing |
| Q35553105 | Thymic stromal lymphopoietin variation, filaggrin loss of function, and the persistence of atopic dermatitis |
| Q79961887 | Tightening the epidermal barrier with atypical PKCs |
| Q61460041 | Tiled array-based sequencing identifies enrichment of loss-of-function variants in the highly homologous filaggrin gene in African-American children with severe atopic dermatitis |
| Q46162487 | Titanium dioxide nanoparticles aggravate atopic dermatitis-like skin lesions in NC/Nga mice |
| Q28511427 | Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects |
| Q35859768 | Transcriptome and ultrastructural changes in dystrophic Epidermolysis bullosa resemble skin aging. |
| Q58859837 | Unique and Recurrent Mutations in the Filaggrin Gene in Singaporean Chinese Patients with Ichthyosis Vulgaris |
| Q91676529 | Unique variants in the FLG gene and FERMT1 gene in a Chinese patient with ichthyosis and Kindler syndrome |
| Q38360676 | Unravelling the complex genetic background of atopic dermatitis: from genetic association results towards novel therapeutic strategies |
| Q64115137 | Untouchable genes in the human genome: Identifying ideal targets for cancer treatment |
| Q37167606 | Update on peptidylarginine deiminases and deimination in skin physiology and severe human diseases. |
| Q37934841 | Updated molecular genetics and pathogenesis of ichthiyoses |
| Q51115827 | Updates from the British Association of Dermatologists 87 th annual meeting, 10-13 July 2007, Birmingham, U.K. |
| Q37407574 | Warm, humid, and high sun exposure climates are associated with poorly controlled eczema: PEER (Pediatric Eczema Elective Registry) cohort, 2004-2012. |
| Q28706284 | Whole-genome sequencing in an autism multiplex family |
| Q43433806 | Wide spectrum of filaggrin-null mutations in atopic dermatitis highlights differences between Singaporean Chinese and European populations. |
| Q54315732 | X-linked recessive ichthyosis: an impaired barrier function evokes limited gene responses before and after moisturizing treatments. |
| Q24306117 | ZNF750 is a p63 target gene that induces KLF4 to drive terminal epidermal differentiation |
| Q60907515 | Zinc in Keratinocytes and Langerhans Cells: Relevance to the Epidermal Homeostasis |
| Q79703339 | [Associated diseases and differential diagnostic considerations in childhood atopic eczema] |
| Q48658169 | [Clinical presentation and etiology of ichthyoses. Overview of the new nomenclature and classification]. |
| Q80275552 | [Filaggrin and genodermatosis: role in icthyosis vulgaris and in atopic dermatitis] |
| Q87140366 | [Genome-associated studies in chronic inflammatory dermatoses] |
| Q82906381 | [New insights into the pathogenesis of sensitive skin] |
| Q79424195 | [Outside-inside or inside-outside? Impaired skin barrier as a primary defect in atopic eczema] |
| Q34123701 | siRNA silencing of proteasome maturation protein (POMP) activates the unfolded protein response and constitutes a model for KLICK genodermatosis |
Search more.