| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2012PLoSO...749845G |
| P356 | DOI | 10.1371/JOURNAL.PONE.0049845 |
| P932 | PMC publication ID | 3504082 |
| P698 | PubMed publication ID | 23185458 |
| P5875 | ResearchGate publication ID | 233775633 |
| P50 | author | Pedro Póvoa | Q38330407 |
| João Gouveia | Q43076766 | ||
| P2093 | author name string | João Gonçalves-Pereira | |
| Carolina Paulino | |||
| Sérgio Janeiro | |||
| Catarina Monteiro | |||
| Alfredo Vieira | |||
| Andrea Salgueiro | |||
| Bruno Serra Oliveira | |||
| Joana Estilita | |||
| Luis Bento | |||
| P2860 | cites work | Is continuous infusion ceftriaxone better than once-a-day dosing in intensive care? A randomized controlled pilot study | Q61699992 |
| Influence of renal function on trough serum concentrations of piperacillin in intensive care unit patients | Q79295065 | ||
| Piperacillin-tazobactam for Pseudomonas aeruginosa infection: clinical implications of an extended-infusion dosing strategy | Q79497432 | ||
| Clinical efficacy of continuous infusion of piperacillin compared with intermittent dosing in septic critically ill patients | Q79827321 | ||
| A systematic review on clinical benefits of continuous administration of beta-lactam antibiotics | Q37454305 | ||
| Antibiotic dosing in multiple organ dysfunction syndrome | Q37871704 | ||
| A randomized study of carbenicillin plus cefamandole or tobramycin in the treatment of febrile episodes in cancer patients | Q40866399 | ||
| Low cefpirome levels during twice daily dosing in critically ill septic patients: pharmacokinetic modelling calls for more frequent dosing. | Q42651670 | ||
| Therapeutic drug monitoring of beta-lactams in critically ill patients: proof of concept | Q42946682 | ||
| First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis | Q43216988 | ||
| Effects of treatment and the metabolic response to injury on drug clearance: a prospective study with piperacillin. | Q43779899 | ||
| Cefepime in intensive care unit patients: validation of a population pharmacokinetic approach and influence of covariables. | Q44228720 | ||
| Cefepime versus cefpirome: the importance of creatinine clearance | Q44590534 | ||
| Alveolar concentrations of piperacillin/tazobactam administered in continuous infusion to patients with ventilator-associated pneumonia | Q44732727 | ||
| Clinical cure of ventilator-associated pneumonia treated with piperacillin/tazobactam administered by continuous or intermittent infusion | Q46159338 | ||
| Glomerular hyperfiltration and albuminuria in critically ill patients | Q46317957 | ||
| Continuous versus intermittent infusion of temocillin, a directed spectrum penicillin for intensive care patients with nosocomial pneumonia: stability, compatibility, population pharmacokinetic studies and breakpoint selection | Q46857071 | ||
| Treating critical illness: the importance of first doing no harm | Q24813804 | ||
| APACHE II: a severity of disease classification system | Q29547729 | ||
| A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study | Q29615430 | ||
| Invited commentary: propensity scores | Q33715877 | ||
| Antibiotic dosing in the 'at risk' critically ill patient: Linking pathophysiology with pharmacokinetics/pharmacodynamics in sepsis and trauma patients | Q33824276 | ||
| Prospective monitoring of cefepime in intensive care unit adult patients | Q33919165 | ||
| Does prolonged β-lactam infusions improve clinical outcomes compared to intermittent infusions? A meta-analysis and systematic review of randomized, controlled trials | Q33940174 | ||
| Low plasma cefepime levels in critically ill septic patients: pharmacokinetic modeling indicates improved troughs with revised dosing | Q33977939 | ||
| Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock | Q34153182 | ||
| Antimicrobial pharmacodynamics: critical interactions of 'bug and drug'. | Q34307105 | ||
| DALI: Defining Antibiotic Levels in Intensive care unit patients: a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic | Q34329290 | ||
| Clinical pharmacokinetics of piperacillin-tazobactam combination in patients with major burns and signs of infection | Q35121815 | ||
| A comparison of estimates of glomerular filtration in critically ill patients with augmented renal clearance | Q35558309 | ||
| Antibiotics in critically ill patients: a systematic review of the pharmacokinetics of β-lactams | Q35908084 | ||
| Continuous versus intermittent intravenous administration of antibiotics: a meta-analysis of randomised controlled trials | Q36240858 | ||
| Does Beta-lactam Pharmacokinetic Variability in Critically Ill Patients Justify Therapeutic Drug Monitoring? A Systematic Review | Q36287127 | ||
| Clinical and microbiological efficacy of continuous versus intermittent application of meropenem in critically ill patients: a randomized open-label controlled trial. | Q36633761 | ||
| Pharmacodynamic optimization of beta-lactams in the patient care setting | Q37169843 | ||
| Better outcomes through continuous infusion of time-dependent antibiotics to critically ill patients? | Q37211603 | ||
| Pharmacokinetic issues for antibiotics in the critically ill patient | Q37399820 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | multicenter clinical trial | Q6934595 |
| piperacillin/tazobactam | Q7197337 | ||
| sepsis | Q183134 | ||
| P304 | page(s) | e49845 | |
| P577 | publication date | 2012-11-21 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Continuous infusion of piperacillin/tazobactam in septic critically ill patients--a multicenter propensity matched analysis | |
| P478 | volume | 7 |
| Q85358743 | Antibiotic dosing in the critically ill: asking the same questions but expecting different answers |
| Q33552161 | Assessment of pharmacokinetic changes of meropenem during therapy in septic critically ill patients |
| Q34892334 | Clinical outcomes with alternative dosing strategies for piperacillin/tazobactam: a systematic review and meta-analysis |
| Q47745708 | Continuous Infusion Versus Intermittent Bolus of Beta-Lactams in Critically Ill Patients with Respiratory Infections: A Systematic Review and Meta-analysis |
| Q64116322 | Continuous versus intermittent infusions of antibiotics for the treatment of infectious diseases: Meta-analysis and systematic review |
| Q58701649 | Pharmacokinetics-pharmacodynamics issues relevant for the clinical use of beta-lactam antibiotics in critically ill patients |
Search more.