scholarly article | Q13442814 |
P2093 | author name string | Masayuki Yamamoto | |
Thomas W Kensler | |||
Sekhar P Reddy | |||
Hannah Lee | |||
Rajesh K Thimmulappa | |||
Shyam Biswal | |||
Tirumalai Rangasamy | |||
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P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | sepsis | Q183134 |
P304 | page(s) | 984-995 | |
P577 | publication date | 2006-04-01 | |
P1433 | published in | Journal of Clinical Investigation | Q3186904 |
P1476 | title | Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis | |
P478 | volume | 116 |
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Q35183080 | Comparative airway inflammatory response of normal volunteers to ozone and lipopolysaccharide challenge |
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Q36739307 | Dangkwisoo-san, an herbal medicinal formula, ameliorates acute lung inflammation via activation of Nrf2 and suppression of NF-κB. |
Q36889964 | Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1 |
Q41929226 | Deficiency in Nrf2-GSH signaling impairs type II cell growth and enhances sensitivity to oxidants |
Q47256841 | Deletion of both p62 and Nrf2 spontaneously results in the development of nonalcoholic steatohepatitis |
Q84744805 | Depletion of Nrf2 enhances inflammation induced by oxyhemoglobin in cultured mice astrocytes |
Q37629316 | Desoxyrhapontigenin up-regulates Nrf2-mediated heme oxygenase-1 expression in macrophages and inflammatory lung injury |
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Q36694999 | Macrophages and Iron Metabolism |
Q91896420 | Maggot Extracts Alleviate Inflammation and Oxidative Stress in Acute Experimental Colitis via the Activation of Nrf2 |
Q90929353 | Magnesium lithospermate B protects the endothelium from inflammation-induced dysfunction through activation of Nrf2 pathway |
Q91796591 | Marine-Steroid Derivative 5α-Androst-3β, 5α, 6β-triol Protects Retinal Ganglion Cells from Ischemia⁻Reperfusion Injury by Activating Nrf2 Pathway |
Q36587125 | Mechanisms for countering oxidative stress and damage in retinal pigment epithelium |
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Q36578703 | Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway |
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Q42219700 | Mifepristone-inducible recombinant adenovirus attenuates paraquat-induced lung injury in rats |
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Q41669241 | Modulation of Caenorhabditis elegans immune response and modification of Shigella endotoxin upon interaction. |
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Q36911318 | Mycoplasma fermentans MALP-2 induces heme oxygenase-1 expression via mitogen-activated protein kinases and Nrf2 pathways to modulate cyclooxygenase 2 expression in human monocytes |
Q98463524 | Mycoplasma hyopneumoniae J elicits an antioxidant response and decreases the expression of ciliary genes in infected swine epithelial cells |
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Q37459975 | Nrf2 protects against TWEAK-mediated skeletal muscle wasting |
Q35817809 | Nrf2 reduces allergic asthma in mice through enhanced airway epithelial cytoprotective function |
Q35622509 | Nrf2 regulates PU.1 expression and activity in the alveolar macrophage |
Q42501152 | Nrf2 regulates an adaptive response protecting against oxidative damage following diquat-mediated formation of superoxide anion |
Q28392051 | Nrf2 regulates chronic lung inflammation and B-cell responses to nontypeable Haemophilus influenzae |
Q30834452 | Nrf2 regulates gene-environment interactions in an animal model of intrauterine inflammation: Implications for preterm birth and prematurity |
Q39775786 | Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease. |
Q37735522 | Nrf2 signaling modulates cigarette smoke-induced complement activation in retinal pigmented epithelial cells |
Q37046924 | Nrf2 signaling: an adaptive response pathway for protection against environmental toxic insults |
Q28395088 | Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription |
Q34031187 | Nrf2, a PPARγ alternative pathway to promote CD36 expression on inflammatory macrophages: implication for malaria |
Q45423906 | Nrf2, a guardian of healthspan and gatekeeper of species longevity |
Q47250925 | Nrf2, the Master Regulator of Anti-Oxidative Responses |
Q37785105 | Nrf2-ARE stress response mechanism: A control point in oxidative stress-mediated dysfunctions and chronic inflammatory diseases |
Q46406217 | Nrf2-Dependent and -Independent Effects of tert-Butylhydroquinone, CDDO-Im, and H2O2 in Human Jurkat T Cells as Determined by CRISPR/Cas9 Gene Editing |
Q37446099 | Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: identification of heat shock response as the major pathway activated by nitro-oleic acid |
Q42155559 | Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide |
Q57125103 | Nrf2-mediated anti-oxidant effects contribute to suppression of non-alcoholic steatohepatitis-associated hepatocellular carcinoma in murine model |
Q34533982 | Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradation |
Q34032853 | Nrf2-regulated PPAR{gamma} expression is critical to protection against acute lung injury in mice |
Q37081392 | Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress |
Q46299719 | Nrf2/ARE pathway inhibits ROS-induced NLRP3 inflammasome activation in BV2 cells after cerebral ischemia reperfusion |
Q36919246 | Nrf2/Keap1 system regulates vascular smooth muscle cell apoptosis for vascular homeostasis: role in neointimal formation after vascular injury |
Q30275291 | Nuclear Factor (Erythroid-Derived 2)-Like 2 and Thioredoxin-1 in Atherosclerosis and Ischemia/Reperfusion Injury in the Heart |
Q37542609 | Nuclear Factor E2-Related Factor-2 Negatively Regulates NLRP3 Inflammasome Activity by Inhibiting Reactive Oxygen Species-Induced NLRP3 Priming |
Q28383171 | Nuclear Factor-Erythroid-2-Related Factor 2 in Aging and Lung Fibrosis |
Q34104811 | Nuclear erythroid 2 p45-related factor 2 inhibits the maturation of murine dendritic cells by ragweed extract |
Q38087926 | Nuclear factor (erythroid-derived 2)-like-2 factor (Nrf2), a key regulator of the antioxidant response to protect against atherosclerosis and nonalcoholic steatohepatitis |
Q28387955 | Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation |
Q41852354 | Nuclear factor-erythroid 2 (NF-E2) p45-related factor-2 (Nrf2) modulates dendritic cell immune function through regulation of p38 MAPK-cAMP-responsive element binding protein/activating transcription factor 1 signaling. |
Q34389786 | Oleanolic acid regulates NF-κB signaling by suppressing MafK expression in RAW 264.7 cells |
Q58699616 | Overexpression of homeodomain-interacting protein kinase 2 (HIPK2) attenuates sepsis-mediated liver injury by restoring autophagy |
Q35943342 | Oxidant-induced cell death and Nrf2-dependent antioxidative response are controlled by Fra-1/AP-1 |
Q43256970 | Oxidative stress in sepsis: a redox redux |
Q90345158 | PL201, a Reported Rhamnoside Against Alzheimer's Disease Pathology, Alleviates Neuroinflammation and Stimulates Nrf2 Signaling |
Q42560760 | PPARγ and Oxidative Stress: Con(β) Catenating NRF2 and FOXO |
Q35577209 | Phospholipid oxidation generates potent anti-inflammatory lipid mediators that mimic structurally related pro-resolving eicosanoids by activating Nrf2. |
Q40346229 | Phytoestrogens modulate hepcidin expression by Nrf2: Implications for dietary control of iron absorption |
Q38620104 | Preclinical evaluation of targeting the Nrf2 pathway by triterpenoids (CDDO-Im and CDDO-Me) for protection from LPS-induced inflammatory response and reactive oxygen species in human peripheral blood mononuclear cells and neutrophils |
Q38442075 | Preconditioning by Low Dose LPS Prevents Subsequent LPS-Induced Severe Liver Injury via Nrf2 Activation in Mice |
Q101226483 | Preconditioning the immature lung with enhanced Nrf2 activity protects against oxidant-induced hypoalveolarization in mice |
Q35852621 | Protective Effect of the Fruit Hull of Gleditsia sinensis on LPS-Induced Acute Lung Injury Is Associated with Nrf2 Activation |
Q54217591 | Protective Role of Nuclear Factor Erythroid 2-Related Factor 2 Against Respiratory Syncytial Virus and Human Metapneumovirus Infections. |
Q28391645 | Protective effect of nuclear factor E2-related factor 2 on inflammatory cytokine response to brominated diphenyl ether-47 in the HTR-8/SVneo human first trimester extravillous trophoblast cell line |
Q46615389 | Protective effects of sulforaphane on di-n-butylphthalate-induced testicular oxidative stress injury in male mice offsprings via activating Nrf2/ARE pathway |
Q36684314 | Protective role of nuclear factor erythroid 2-related factor 2 in the hemorrhagic shock-induced inflammatory response |
Q41500103 | Proteomic analysis of brain protein expression levels in NF-kappabeta p50 -/- homozygous knockout mice |
Q89701868 | Pyrocatechol, a component of coffee, suppresses LPS-induced inflammatory responses by inhibiting NF-κB and activating Nrf2 |
Q37620581 | RETRACTED ARTICLE: Wogonin reversed resistant human myelogenous leukemia cells via inhibiting Nrf2 signaling by Stat3/NF-κB inactivation |
Q29615229 | ROS function in redox signaling and oxidative stress |
Q33724561 | ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function |
Q35512908 | RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity |
Q39324573 | Recombinant adenovirus Ad-RUNrf2 reduces paraquat-induced A549 injury. |
Q58221929 | Red wine polyphenol extract efficiently protects intestinal epithelial cells from inflammation opposite modulation of JAK/STAT and Nrf2 pathways |
Q27000279 | Redox control of microglial function: molecular mechanisms and functional significance |
Q34138063 | Regenerative stromal cell therapy in allogeneic hematopoietic stem cell transplantation: current impact and future directions |
Q58749129 | Regional Differences in Airway Epithelial Cells Reveal Tradeoff between Defense against Oxidative Stress and Defense against Rhinovirus |
Q28354293 | Regressive Effect of Myricetin on Hepatic Steatosis in Mice Fed a High-Fat Diet |
Q24655260 | Regulation of glutathione synthesis |
Q37765106 | Regulation of innate immune responses by autophagy-related proteins |
Q34731017 | Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells |
Q39426145 | Resveratrol protects against lipopolysaccharide-induced cardiac dysfunction by enhancing SERCA2a activity through promoting the phospholamban oligomerization |
Q37122677 | Retinal microenvironment imbalance in dry age-related macular degeneration: a mini-review |
Q41816145 | Role of Nrf2 in host defense against influenza virus in cigarette smoke-exposed mice |
Q37853027 | Role of glutathione in immunity and inflammation in the lung |
Q36634711 | Role of lung maintenance program in the heterogeneity of lung destruction in emphysema |
Q38750932 | Role of microRNAs in sepsis |
Q38237494 | Role of the Nrf2 signaling system in health and disease |
Q27026726 | Roles nrf2 plays in myeloid cells and related disorders |
Q28594591 | Roles of peroxiredoxin II in the regulation of proinflammatory responses to LPS and protection against endotoxin-induced lethal shock |
Q100427974 | SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate |
Q35857245 | Selective and nonselective packaging of cellular RNAs in retrovirus particles |
Q43203144 | Sepsis: redox mechanisms and therapeutic opportunities |
Q37696365 | Sesamin inhibits IL-1β-stimulated inflammatory response in human osteoarthritis chondrocytes by activating Nrf2 signaling pathway |
Q91638165 | Sikyungbanha-Tang Suppressing Acute Lung Injury in Mice Is Related to the Activation of Nrf2 and TNFAIP3 |
Q40386699 | Skin Damage Mechanisms Related to Airborne Particulate Matter Exposure |
Q89964433 | Stress Memory of Recurrent Environmental Challenges in Marine Invasive Species: Ciona robusta as a Case Study |
Q60048684 | Structural instability of IκB kinase β promotes autophagic degradation through enhancement of Keap1 binding |
Q37402358 | Sulforaphane Protects Pancreatic Acinar Cell Injury by Modulating Nrf2-Mediated Oxidative Stress and NLRP3 Inflammatory Pathway |
Q39576582 | Sulforaphane inhibits de novo synthesis of IL-8 and MCP-1 in human epithelial cells generated by cigarette smoke extract |
Q51595565 | Sulforaphane is anticonvulsant and improves mitochondrial function. |
Q40240331 | Sulforaphane reduces lipopolysaccharide-induced proinflammatory markers in hippocampus and liver but does not improve sickness behavior |
Q46302495 | Suppressed ubiquitination of Nrf2 by p47phox contributes to Nrf2 activation |
Q34374994 | Suppression of lung inflammation in an LPS-induced acute lung injury model by the fruit hull of Gleditsia sinensis |
Q35040534 | Sustained activation of nuclear erythroid 2-related factor 2/antioxidant response element signaling promotes reductive stress in the human mutant protein aggregation cardiomyopathy in mice |
Q39931462 | Synergistic effect of combination of phenethyl isothiocyanate and sulforaphane or curcumin and sulforaphane in the inhibition of inflammation |
Q36293645 | Synthetic oleanane triterpenoids: multifunctional drugs with a broad range of applications for prevention and treatment of chronic disease. |
Q90122888 | Tanshinone IIA pretreatment promotes cell survival in human lung epithelial cells under hypoxia via AP-1-Nrf2 transcription factor |
Q36178212 | Targeted deletion of nrf2 impairs lung development and oxidant injury in neonatal mice |
Q37054081 | Targeting Nrf2 signaling improves bacterial clearance by alveolar macrophages in patients with COPD and in a mouse model |
Q38786854 | Targeting the KEAP1-NRF2 System to Prevent Kidney Disease Progression |
Q28396391 | Th2 skewing by activation of Nrf2 in CD4(+) T cells |
Q38837451 | The Keap1-Nrf2-ARE Pathway As a Potential Preventive and Therapeutic Target: An Update |
Q28385998 | The Nrf2 activator tBHQ inhibits T cell activation of primary human CD4 T cells |
Q28391095 | The Nrf2 activator, tBHQ, differentially affects early events following stimulation of Jurkat cells |
Q38114031 | The Nrf2 pathway in the progression of renal disease |
Q34984506 | The Nrf2-ARE cytoprotective pathway in astrocytes |
Q26741190 | The Role of Cyclo(His-Pro) in Neurodegeneration |
Q55384251 | The Role of Mitophagy in Innate Immunity. |
Q89621868 | The Role of Nrf2 in Cellular Innate Immune Response to Inflammatory Injury |
Q92702814 | The Role of Nrf2 in the Antioxidant Cellular Response to Medical Ozone Exposure |
Q57051340 | The Synergy of Aging and LPS Exposure in a Mouse Model of Parkinson's Disease |
Q35865287 | The absence of Nrf2 enhances NF-κB-dependent inflammation following scratch injury in mouse primary cultured astrocytes |
Q30495467 | The absence of the pro-antioxidant transcription factor Nrf2 exacerbates experimental autoimmune encephalomyelitis |
Q39295165 | The anti-inflammatory effect of melatonin on methamphetamine-induced proinflammatory mediators in human neuroblastoma dopamine SH-SY5Y cell lines |
Q28389296 | The complexity of the Nrf2 pathway: beyond the antioxidant response |
Q35067749 | The effect of ex vivo CDDO-Me activation on nuclear factor erythroid 2-related factor 2 pathway in white blood cells from patients with septic shock |
Q38026675 | The endoplasmic reticulum: a sensor of cellular stress that modulates immune responses |
Q37596452 | The glutathione peroxidase 1-protein tyrosine phosphatase 1B-protein phosphatase 2A axis. A key determinant of airway inflammation and alveolar destruction |
Q89599590 | The methanol extract of Guettarda speciosa Linn. Ameliorates acute lung injury in mice |
Q38166575 | The nrf1 and nrf2 balance in oxidative stress regulation and androgen signaling in prostate cancer cells |
Q34687796 | The plant-based immunomodulator curcumin as a potential candidate for the development of an adjunctive therapy for cerebral malaria |
Q35623650 | The redox-sensitive transcription factor Nrf2 regulates murine hematopoietic stem cell survival independently of ROS levels. |
Q38867621 | The regulation of inflammation by oxidized phospholipids |
Q46978063 | The role of declining adaptive homeostasis in ageing |
Q39013645 | The role of nuclear factor-erythroid 2 related factor 2 (Nrf-2) in the protection against lung injury |
Q37891127 | The role of oxidative stress and innate immunity in O(3) and endotoxin-induced human allergic airway disease |
Q88617041 | The role of oxidative stress in anxiety disorder: cause or consequence? |
Q34175650 | The synthetic triterpenoid, CDDO-Me, modulates the proinflammatory response to in vivo lipopolysaccharide challenge |
Q35684749 | The tobacco smoke component, acrolein, suppresses innate macrophage responses by direct alkylation of c-Jun N-terminal kinase |
Q49476384 | The triterpenoid CDDO-imidazolide reduces immune cell infiltration and cytokine secretion in the KrasG12D;Pdx1-Cre (KC) mouse model of pancreatic cancer |
Q98725936 | The α2 Na+/K+-ATPase isoform mediates LPS-induced neuroinflammation |
Q37162845 | Therapeutic Effect of Chung-Pae, an Experimental Herbal Formula, on Acute Lung Inflammation Is Associated with Suppression of NF- κ B and Activation of Nrf2. |
Q37101039 | Therapeutic Effect of the Tuber of Alisma orientale on Lipopolysaccharide-Induced Acute Lung Injury |
Q90893987 | Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases |
Q34122340 | Toxic effects of maternal zearalenone exposure on intestinal oxidative stress, barrier function, immunological and morphological changes in rats |
Q42165757 | Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice |
Q42514932 | Transcriptional Regulation by Nrf2. |
Q36796876 | Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer. |
Q38805723 | TrxR1 inhibition overcomes both hypoxia-induced and acquired bortezomib resistance in multiple myeloma through NF-кβ inhibition. |
Q39123548 | Unravelling the networks dictating host resistance versus tolerance during pulmonary infections. |
Q95856528 | Unveiling the Role of Inflammation and Oxidative Stress on Age-Related Cardiovascular Diseases |
Q36769694 | Update in critical care 2006. |
Q50180900 | Violet/blue light activates Nrf2 signaling and modulates the inflammatory response of THP-1 monocytes |
Q43781810 | Water-soluble phenol TS-13 combats acute but not chronic inflammation |
Q28384223 | When NRF2 talks, who's listening? |
Q36070027 | Whole-Body In Vivo Monitoring of Inflammatory Diseases Exploiting Human Interleukin 6-Luciferase Transgenic Mice |
Q80133280 | [Clinical use of diagnostic laboratory tests in childhood sepsis] |
Q91785228 | miR‑148 family members are putative biomarkers for sepsis |
Q92366410 | miR‑195 promotes LPS‑mediated intestinal epithelial cell apoptosis via targeting SIRT1/eIF2a |
Q90448213 | p-Coumaric acid protects cardiac function against lipopolysaccharide-induced acute lung injury by attenuation of oxidative stress |
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