Evaluation of peripheral blood mononuclear cell processing and analysis for Survival Motor Neuron protein

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Evaluation of peripheral blood mononuclear cell processing and analysis for Survival Motor Neuron protein is …
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scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...750763K
P356DOI10.1371/JOURNAL.PONE.0050763
P932PMC publication ID3511312
P698PubMed publication ID23226377
P5875ResearchGate publication ID233888987

P2093author name stringDione T Kobayashi
Karen S Chen
Nabil Ghazal
Phillip Zaworski
Laurel Sly
Brett Chung
Douglas Decker
James Vanderlugt
Julie McGonigal
Karen Klott
P2860cites workDNAse treatment following thawing of cryopreserved PBMC is a procedure suitable for lymphocyte functional studies.Q53799252
Quantification of SMN protein in leucocytes from spinal muscular atrophy patients: effects of treatment with valproic acidQ60361416
Enhanced rates and magnitude of immune responses detected against an HIV vaccine: effect of using an optimized process for isolating PBMCQ64377277
Comparison of cytokine production in blood cell cultures of healthy children and adultsQ71375846
In vivo activation of SMN in spinal muscular atrophy carriers and patients treated with valproateQ83139606
Survival probabilities of patients with childhood spinal muscle atrophyQ83422469
Isolation and preservation of peripheral blood mononuclear cells for analysis of islet antigen-reactive T cell responses: position statement of the T-Cell Workshop Committee of the Immunology of Diabetes SocietyQ37799656
Biomarkers in rare disorders: the experience with spinal muscular atrophyQ37845667
Spinal muscular atrophy: a clinical and research updateQ37971125
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A two-site ELISA can quantify upregulation of SMN protein by drugs for spinal muscular atrophy.Q39960453
SMN mRNA and protein levels in peripheral blood: biomarkers for SMA clinical trialsQ40315627
Lentivector-mediated SMN replacement in a mouse model of spinal muscular atrophy.Q40480552
Valproic acid increases SMN levels in spinal muscular atrophy patient cells.Q40620622
Preclinical validation of a multiplex real-time assay to quantify SMN mRNA in patients with SMAQ40882876
Correlation between severity and SMN protein level in spinal muscular atrophyQ41102726
RETRACTED ARTICLE: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMNQ41275236
Time-dependent changes in the expression of lymphocyte and monocyte cell adhesion molecules after meals of different compositionQ42475429
The activity of the spinal muscular atrophy protein is regulated during development and cellular differentiation.Q42485526
Spinal muscular atrophy: survival pattern and functional statusQ43315814
Intravenous scAAV9 delivery of a codon-optimized SMN1 sequence rescues SMA miceQ45865368
Expression levels for many genes in human peripheral blood cells are highly sensitive to ex vivo incubationQ47399907
SMN transcript levels in leukocytes of SMA patients determined by absolute real-time PCRQ24599124
Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanismQ24613087
Delivery of recombinant follistatin lessens disease severity in a mouse model of spinal muscular atrophyQ24647245
Salbutamol increases SMN mRNA and protein levels in spinal muscular atrophy cellsQ28252944
The changing natural history of spinal muscular atrophy type 1Q28257091
Phenylbutyrate increases SMN gene expression in spinal muscular atrophy patientsQ28291453
Salbutamol increases survival motor neuron (SMN) transcript levels in leucocytes of spinal muscular atrophy (SMA) patients: relevance for clinical trial designQ28293151
Standardized peripheral blood mononuclear cell culture assay for determination of drug susceptibilities of clinical human immunodeficiency virus type 1 isolates.Q28378727
Evaluation of SMN protein, transcript, and copy number in the biomarkers for spinal muscular atrophy (BforSMA) clinical studyQ28730280
Candidate proteins, metabolites and transcripts in the Biomarkers for Spinal Muscular Atrophy (BforSMA) clinical studyQ28730283
Utility of survival motor neuron ELISA for spinal muscular atrophy clinical and preclinical analysesQ28740896
Consensus Statement for Standard of Care in Spinal Muscular AtrophyQ29028573
Effects of 2,4-diaminoquinazoline derivatives on SMN expression and phenotype in a mouse model for spinal muscular atrophyQ30492560
CNS-targeted gene therapy improves survival and motor function in a mouse model of spinal muscular atrophyQ30493891
A novel cell immunoassay to measure survival of motor neurons protein in blood cellsQ33232855
VACUTAINER CPT and Ficoll density gradient separation perform equivalently in maintaining the quality and function of PBMC from HIV seropositive blood samplesQ33244711
Treatment of spinal muscular atrophy by sodium butyrateQ33933841
Viability and recovery of peripheral blood mononuclear cells cryopreserved for up to 12 years in a multicenter study.Q33997498
Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse modelQ34030144
Collection and processing of whole blood for transformation of peripheral blood mononuclear cells and extraction of DNA: the Type 1 Diabetes Genetics ConsortiumQ34051595
Gene Expression Profiles from Peripheral Blood Mononuclear Cells Are Sensitive to Short Processing DelaysQ34199302
Progress and promise: the current status of spinal muscular atrophy therapeutics.Q34227846
A single administration of morpholino antisense oligomer rescues spinal muscular atrophy in mouseQ34241874
Quantitative analyses of SMN1 and SMN2 based on real-time lightCycler PCR: fast and highly reliable carrier testing and prediction of severity of spinal muscular atrophyQ34353103
Tetracyclines that promote SMN2 exon 7 splicing as therapeutics for spinal muscular atrophyQ34616822
Natural history of denervation in SMA: relation to age, SMN2 copy number, and functionQ35101830
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)e50763
P577publication date2012-11-30
P1433published inPLOS OneQ564954
P1476titleEvaluation of peripheral blood mononuclear cell processing and analysis for Survival Motor Neuron protein
P478volume7

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cites work (P2860)
Q36205773A Comparative Study of SMN Protein and mRNA in Blood and Fibroblasts in Patients with Spinal Muscular Atrophy and Healthy Controls
Q34082155Assays for the identification and prioritization of drug candidates for spinal muscular atrophy
Q36565221Baseline results of the NeuroNEXT spinal muscular atrophy infant biomarker study.
Q35808086Biomarker for Spinal Muscular Atrophy: Expression of SMN in Peripheral Blood of SMA Patients and Healthy Controls
Q34658131SMA-MAP: a plasma protein panel for spinal muscular atrophy
Q35949008SMN Protein Can Be Reliably Measured in Whole Blood with an Electrochemiluminescence (ECL) Immunoassay: Implications for Clinical Trials
Q42638317Survival Motor Neuron Protein is Released from Cells in Exosomes: A Potential Biomarker for Spinal Muscular Atrophy.

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