miR-105/Runx2 axis mediates FGF2-induced ADAMTS expression in osteoarthritis cartilage

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miR-105/Runx2 axis mediates FGF2-induced ADAMTS expression in osteoarthritis cartilage is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1009589627
P356DOI10.1007/S00109-016-1380-9
P698PubMed publication ID26816250

P50authorQuanbo JiQ91833458
P2093author name stringYan Wang
Ling Li
Qiang Zhang
Jing Guo
Xiaojie Xu
Lei Kang
Qinong Ye
Tian Hong
Yameng Xu
Yingchun Liang
Zhongli Li
Zhongyi Fan
P2860cites workInhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulinQ24313406
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Leptin plays a catabolic role on articular cartilageQ28576942
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Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasisQ33591140
MicroRNA-140 plays dual roles in both cartilage development and homeostasisQ33885698
Interleukin-1β induces differentiation of human mesenchymal stem cells into osteoblasts via the Wnt-5a/receptor tyrosine kinase-like orphan receptor 2 pathway.Q50509527
Celecoxib exerts protective effects on extracellular matrix metabolism of mandibular condylar chondrocytes under excessive mechanical stress.Q53058607
Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cellsQ54400886
Histone deacetylase inhibitors increase microRNA-146a expression and enhance negative regulation of interleukin-1β signaling in osteoarthritis fibroblast-like synoviocytes.Q54404385
MiR-30a inhibits osteolysis by targeting RunX2 in giant cell tumor of boneQ85648241
Basic fibroblast growth factor stimulates matrix metalloproteinase-13 via the molecular cross-talk between the mitogen-activated protein kinases and protein kinase Cdelta pathways in human adult articular chondrocytesQ33953872
Cyclin-dependent kinase 9 inhibition protects cartilage from the catabolic effects of proinflammatory cytokinesQ34022536
MiR-152 suppresses the proliferation and invasion of NSCLC cells by inhibiting FGF2Q34116259
The expression and function of microRNAs in chondrogenesis and osteoarthritis.Q34238501
The NF-κB member p65 controls glutamine metabolism through miR-23a.Q34277479
An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertensionQ34319305
Impact of exercise type and dose on pain and disability in knee osteoarthritis: a systematic review and meta-regression analysis of randomized controlled trialsQ34407133
Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberranciesQ34475490
miR-105 inhibits prostate tumour growth by suppressing CDK6 levelsQ34947109
MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes.Q35114604
MicroRNA-199a* regulates the expression of cyclooxygenase-2 in human chondrocytesQ35875196
MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytesQ35962544
Hepatitis B virus X protein represses miRNA-148a to enhance tumorigenesisQ36580378
MicroRNA-125b regulates the expression of aggrecanase-1 (ADAMTS-4) in human osteoarthritic chondrocytesQ36903284
MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcomaQ37175182
The role of ADAMTS-7 and ADAMTS-12 in the pathogenesis of arthritis.Q37355734
Deletion of the transforming growth factor β receptor type II gene in articular chondrocytes leads to a progressive osteoarthritis-like phenotype in miceQ37591885
Opposing TNF-α/IL-1β- and BMP-2-activated MAPK signaling pathways converge on Runx2 to regulate BMP-2-induced osteoblastic differentiationQ37726092
Macro view of microRNA function in osteoarthritisQ38034389
Fibroblast growth factor control of cartilage homeostasisQ38051582
The long and short of microRNA.Q38102186
Review: the role of microRNAs in osteoarthritis and chondrogenesisQ38105988
The NF-κB signalling pathway in osteoarthritisQ38134203
Osteoarthritis research priorities: a report from a EULAR ad hoc expert committeeQ38195690
Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilageQ38475385
Role of microRNA‑503 in the suppression of osteosarcoma cell proliferation and migration via modulation of fibroblast growth factor 2.Q38828344
MicroRNA-23b is an independent prognostic marker and suppresses ovarian cancer progression by targeting runt-related transcription factor-2.Q39016879
Transcriptional cooperation between p53 and NF-κB p65 regulates microRNA-224 transcription in mouse ovarian granulosa cells.Q39183106
Elevated expression of CUEDC2 protein confers endocrine resistance in breast cancer.Q39542346
MiR-203 controls proliferation, migration and invasive potential of prostate cancer cell lines.Q39582762
Differential expression of microRNA in endothelial cells incubated with serum of hypertension patients with blood-stasis syndromeQ40271435
Chondrocyte-intrinsic Smad3 represses Runx2-inducible matrix metalloproteinase 13 expression to maintain articular cartilage and prevent osteoarthritis.Q41964841
Inhibition of bone resorption blunts osteoarthritis in mice with high bone remodelling.Q43043830
Upregulation of ANK protein expression in joint tissue in calcium pyrophosphate dihydrate crystal deposition diseaseQ44713636
Overexpression of hsa-miR-148a promotes cartilage production and inhibits cartilage degradation by osteoarthritic chondrocytesQ45826317
Monosodium urate monohydrate crystals inhibit osteoblast viability and function: implications for development of bone erosion in gout.Q45946436
IL-6-accelerated calcification by induction of ROR2 in human adipose tissue-derived mesenchymal stem cells is STAT3 dependentQ46285488
P433issue6
P921main subjectosteoarthritisQ62736
cartilageQ502730
P304page(s)681-694
P577publication date2016-01-27
P1433published inJournal of Molecular MedicineQ6295593
P1476titlemiR-105/Runx2 axis mediates FGF2-induced ADAMTS expression in osteoarthritis cartilage
P478volume94

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cites work (P2860)
Q92392859Association of circulating microRNAs with prevalent and incident knee osteoarthritis in women: the OFELY study
Q52586734Combined bioinformatics analysis reveals gene expression and DNA methylation patterns in osteoarthritis.
Q55177192Cryptotanshinone Protects Cartilage against Developing Osteoarthritis through the miR-106a-5p/GLIS3 Axis.
Q33725812Deletion of Runx2 in Articular Chondrocytes Decelerates the Progression of DMM-Induced Osteoarthritis in Adult Mice
Q55279885Downregulation of HS6ST2 by miR-23b-3p enhances matrix degradation through p38 MAPK pathway in osteoarthritis.
Q47784837Extracellular genomic biomarkers of osteoarthritis
Q60907377Hematopoietic PBX-interacting protein mediates cartilage degeneration during the pathogenesis of osteoarthritis
Q49478023MicroRNA-17-5p contributes to osteoarthritis progression by binding p62/SQSTM1.
Q58805128MicroRNAs and Osteoarthritis
Q58800992Onset and Progression of Human Osteoarthritis-Can Growth Factors, Inflammatory Cytokines, or Differential miRNA Expression Concomitantly Induce Proliferation, ECM Degradation, and Inflammation in Articular Cartilage?
Q38928077Runx2 and microRNA regulation in bone and cartilage diseases
Q39020213Small non-coding RNAs-based bone regulation and targeting therapeutic strategies.
Q47228254TET2 Loss Dysregulates the Behavior of Bone Marrow Mesenchymal Stromal Cells and Accelerates Tet2-/--Driven Myeloid Malignancy Progression
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Q88301412miR-223-3p Inhibits Human Osteosarcoma Metastasis and Progression by Directly Targeting CDH6
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Q57128464miR-409 Inhibits Human Non-Small-Cell Lung Cancer Progression by Directly Targeting SPIN1
Q58796481miR‑204‑5p inhibits the occurrence and development of osteoarthritis by targeting Runx2

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