Autophagy is essential for effector CD8(+) T cell survival and memory formation

scientific article

Autophagy is essential for effector CD8(+) T cell survival and memory formation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NI.3025
P932PMC publication ID4232981
P698PubMed publication ID25362489
P5875ResearchGate publication ID267738058

P50authorDouglas R. GreenQ19667788
Herbert W. VirginQ28407524
Rafi AhmedQ29017279
Lilin YeQ56441998
Jennifer MartinezQ61873164
P2093author name stringDean P Jones
Bogumila T Konieczny
Koichi Araki
Monique W Bruinsma
Shuzhao Li
Erika L Pearce
Jin-Hwan Han
Xiaojin Xu
Wendy G Tan
P2860cites workThe selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1Q24300456
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagyQ24312147
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profilesQ24536351
Autophagy in immunity and inflammationQ24595707
Viral immune evasion due to persistence of activated T cells without effector functionQ24646943
mTOR regulates memory CD8 T-cell differentiationQ24648624
Autophagy modulation as a potential therapeutic target for diverse diseasesQ27010076
Suppression of basal autophagy in neural cells causes neurodegenerative disease in miceQ28131756
Modelling T-cell memory by genetic marking of memory T cells in vivoQ28137842
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1Q28506431
Methods in mammalian autophagy researchQ29547276
Autophagy regulates lipid metabolismQ29547421
The role of autophagy during the early neonatal starvation periodQ29547489
Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3Q29614176
apLCMS--adaptive processing of high-resolution LC/MS dataQ33438817
Enhancing CD8 T-cell memory by modulating fatty acid metabolismQ33577204
Memory CD8(+) T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development.Q33997387
Autophagy is induced in CD4+ T cells and important for the growth factor-withdrawal cell deathQ33999904
The complex interplay between autophagy, apoptosis, and necrotic signals promotes T-cell homeostasisQ34252212
The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolismQ34411887
Effector and memory CTL differentiationQ34584974
Macroautophagy regulates energy metabolism during effector T cell activationQ34615092
Predicting network activity from high throughput metabolomicsQ34824962
Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairmentQ34857689
Quantitating the magnitude of the lymphocytic choriomeningitis virus-specific CD8 T-cell response: it is even bigger than we thoughtQ35635463
Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunityQ35709263
Selective autophagy of the adaptor protein Bcl10 modulates T cell receptor activation of NF-κB.Q36074808
Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factorQ36082833
Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infectionQ36202704
A critical role for the autophagy gene Atg5 in T cell survival and proliferationQ36228924
Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasisQ36427380
Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fatesQ36509866
Natural killer cells act as rheostats modulating antiviral T cellsQ36517134
Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasisQ37019194
Identification of Atg5-dependent transcriptional changes and increases in mitochondrial mass in Atg5-deficient T lymphocytes.Q37079467
Autophagy variation within a cell population determines cell fate through selective degradation of Fap-1.Q37420801
Autophagy in cellular growth controlQ37680207
Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory developmentQ40760682
Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytesQ41486560
Mantle skewness and ridge segmentationQ41996834
IL-7 enhances the survival and maintains the size of naive T cellsQ43819910
Utilizing flow cytometry to monitor autophagy in living mammalian cellsQ44821204
Autophagy is essential for mitochondrial clearance in mature T lymphocytesQ45162920
Mitochondrial Potential and Reactive Oxygen Intermediates in Antigen-Specific CD8+ T Cells During Viral InfectionQ47960185
Genetic reconstitution of bone marrow for the study of signal transduction ex vivo.Q50720918
Revving the engine: signal transduction fuels T cell activation.Q50926090
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.Q52004225
Molecular and functional profiling of memory CD8 T cell differentiation.Q52008481
Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.Q52040367
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectautophagyQ288322
memory formationQ107596539
P304page(s)1152-1161
P577publication date2014-11-02
P1433published inNature ImmunologyQ1071725
P1476titleAutophagy is essential for effector CD8(+) T cell survival and memory formation
P478volume15

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