| scholarly article | Q13442814 |
| P50 | author | Richard Flavell | Q2149481 |
| P2093 | author name string | Sean T Kim | |
| Patrick E Fields | |||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | histone acetylation | Q14908264 |
| P304 | page(s) | 647-650 | |
| P577 | publication date | 2002-07-01 | |
| P1433 | published in | Journal of Immunology | Q3521441 |
| P1476 | title | Cutting edge: changes in histone acetylation at the IL-4 and IFN-gamma loci accompany Th1/Th2 differentiation | |
| P478 | volume | 169 |
| Q38106128 | 'All things considered': transcriptional regulation of T helper type 2 cell differentiation from precursor to effector activation |
| Q27863347 | 1-Methyl-tryptophan can interfere with TLR signaling in dendritic cells independently of IDO activity |
| Q81439951 | A DNA adjuvant encoding a fusion protein between anti-CD3 single-chain Fv and AIMP1 enhances T helper type 1 cell-mediated immune responses in antigen-sensitized mice |
| Q38325300 | A critical control element for interleukin-4 memory expression in T helper lymphocytes |
| Q40532205 | A distal region in the interferon-gamma gene is a site of epigenetic remodeling and transcriptional regulation by interleukin-2. |
| Q95329570 | A highly polarized TH2 bladder response to infection promotes epithelial repair at the expense of preventing new infections |
| Q37388179 | A tale of two STAT6 knock out mice in the induction of experimental autoimmune encephalomyelitis |
| Q52098330 | Active recruitment of DNA methyltransferases regulates interleukin 4 in thymocytes and T cells |
| Q36958316 | Aging-dependent upregulation of IL-23p19 gene expression in dendritic cells is associated with differential transcription factor binding and histone modifications |
| Q55506187 | Air pollutants and early origins of respiratory diseases. |
| Q37768553 | Allergic disease: understanding how in utero events set the scene |
| Q36734975 | Allergic disorders in African countries: linking immunology to accurate phenotype |
| Q27860939 | Alternative activation of macrophages |
| Q35164202 | An epigenetic view of helper T cell differentiation |
| Q45288383 | An intron GATA-binding site regulates chromatin accessibility and is essential for IL-4 gene expression in mast cells |
| Q36994959 | BRG1-mediated chromatin remodeling regulates differentiation and gene expression of T helper cells |
| Q37058781 | Biomarkers in systemic lupus erythematosus: challenges and prospects for the future |
| Q91936795 | Bromodomain inhibitor JQ1 reversibly blocks IFN-γ production |
| Q47897416 | CD28 costimulation controls histone hyperacetylation of the interleukin 5 gene locus in developing th2 cells |
| Q59762566 | CD8 T Cell-Specific Downregulation of Histone Hyperacetylation and Gene Activation of the IL-4 Gene Locus by ROG, Repressor of GATA |
| Q35574709 | CXCL8 histone H3 acetylation is dysfunctional in airway smooth muscle in asthma: regulation by BET |
| Q35583494 | Cell‐cycle regulation of T‐cell responses – novel approaches to the control of alloimmunity |
| Q39742078 | Changes in chromatin structure and methylation of the human interleukin-1beta gene during monopoiesis. |
| Q37388788 | Chromatin landscape dynamics of the Il4-Il13 locus during T helper 1 and 2 development |
| Q42929533 | Chromatin remodeling by the SWI/SNF-like BAF complex and STAT4 activation synergistically induce IL-12Rbeta2 expression during human Th1 cell differentiation |
| Q28383437 | Clinical implications of interferon-γ genetic and epigenetic variants |
| Q36282244 | Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-gamma |
| Q38505117 | Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production |
| Q36371748 | Constitutive Cytokine mRNAs Mark Natural Killer (NK) and NK T Cells Poised for Rapid Effector Function |
| Q34013155 | Cutting edge: the Th1 response inhibits the generation of peripheral regulatory T cells |
| Q35150010 | Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights. |
| Q56902320 | Cytotoxic T-lymphocyte antigen-4 inhibits GATA-3 but not T-bet mRNA expression during T helper cell differentiation |
| Q60182798 | Deletion of a conserved Il4 silencer impairs T helper type 1–mediated immunity |
| Q47438852 | Delta1-Notch3 interactions bias the functional differentiation of activated CD4+ T cells |
| Q36089273 | Demethylation of a specific hypersensitive site in the Th2 locus control region |
| Q34971900 | Differential DNA methylation regions in cytokine and transcription factor genomic loci associate with childhood physical aggression |
| Q44997621 | Discrete roles for histone acetylation in human T helper 1 cell-specific gene expression |
| Q35102079 | Dynamic BRG1 recruitment during T helper differentiation and activation reveals distal regulatory elements |
| Q41437486 | Dynamic DNA methylation patterns across the mouse and human IL10 genes during CD4+ T cell activation; influence of IL-27. |
| Q50898645 | Dynamic changes in histone-methylation 'marks' across the locus encoding interferon-gamma during the differentiation of T helper type 2 cells. |
| Q39970299 | Dynamic protein associations define two phases of IL-1beta transcriptional activation. |
| Q33756571 | Effector CD4 cell tolerization is mediated through functional inactivation and involves preferential impairment of TNF-alpha and IFN-gamma expression potentials |
| Q31139260 | Environmental alkylphenols modulate cytokine expression in plasmacytoid dendritic cells |
| Q28388771 | Environmental epigenetics of asthma: An update |
| Q36203475 | Environmental epigenetics: prospects for studying epigenetic mediation of exposure-response relationships |
| Q64104439 | Epigenetic Modifications in Placenta are Associated with the Child's Sensitization to Allergens |
| Q37371624 | Epigenetic control of T-helper-cell differentiation |
| Q38107626 | Epigenetic control of cytokine gene expression: regulation of the TNF/LT locus and T helper cell differentiation |
| Q35042509 | Epigenetic control of gene expression in the lung |
| Q35649230 | Epigenetic inheritance of fetal genes in allergic asthma. |
| Q35618602 | Epigenetic manipulation restores functions of defective CD8⁺ T cells from chronic viral infection |
| Q36456175 | Epigenetic mechanisms and the development of asthma |
| Q24606049 | Epigenetic regulation in allergic diseases and related studies |
| Q37191342 | Epigenetic regulation of Th2 cytokine expression in atopic diseases. |
| Q34777193 | Epigenetic regulation of beta2-adrenergic receptor expression in TH1 and TH2 cells |
| Q37536992 | Epigenetic regulation of cytokine gene expression in T lymphocytes |
| Q40103534 | Epigenetic silencing of tumor necrosis factor alpha during endotoxin tolerance |
| Q37380019 | Epigenetics and T helper 1 differentiation |
| Q34590978 | Epigenetics and T-cell immunity |
| Q36428883 | Epigenetics and the adaptive immune response |
| Q28730790 | Epigenetics: connecting environment and genotype to phenotype and disease |
| Q28256853 | Essential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene loci |
| Q37494109 | Evolutionarily conserved sequence elements that positively regulate IFN-gamma expression in T cells |
| Q82951658 | Explaining discordant coordination |
| Q24299602 | FOXP3 ensembles in T-cell regulation |
| Q24300168 | FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression |
| Q37637601 | Functionality and opposite roles of two interleukin 4 haplotypes in immune cells. |
| Q43242886 | G9a and HP1 couple histone and DNA methylation to TNFalpha transcription silencing during endotoxin tolerance |
| Q37544473 | GADD45beta/GADD45gamma and MEKK4 comprise a genetic pathway mediating STAT4-independent IFNgamma production in T cells. |
| Q87955785 | Genetic and epigenetic influences on the loss of tolerance in autoimmunity |
| Q37498951 | Genetic and epigenetic networks controlling T helper 1 cell differentiation. |
| Q37259809 | Genome-wide analysis of histone methylation reveals chromatin state-based regulation of gene transcription and function of memory CD8+ T cells |
| Q33566569 | HDAC4 is expressed on multiple T cell lineages but dispensable for their development and function |
| Q35176407 | Helper T cell differentiation and the problem of cellular inheritance |
| Q37362239 | Heterogeneity in the CD4 T Cell Compartment and the Variability of Neonatal Immune Responsiveness |
| Q33791226 | Histone acetylation at the Ifng promoter in tolerized CD4 cells is associated with increased IFN-gamma expression during subsequent immunization to the same antigen |
| Q34784615 | Histone acetylation facilitates rapid and robust memory CD8 T cell response through differential expression of effector molecules (eomesodermin and its targets: perforin and granzyme B). |
| Q35848699 | Histone acetylation is associated with differential gene expression in the rapid and robust memory CD8(+) T-cell response |
| Q57143889 | Histone deacetylase function in CD4 T cells |
| Q34131663 | Histone hyperacetylated domains across the Ifng gene region in natural killer cells and T cells |
| Q81168086 | Hypersensitive site 7 of the TH2 locus control region is essential for expressing TH2 cytokine genes and for long-range intrachromosomal interactions |
| Q36736178 | IFN-γ suppresses permissive chromatin remodeling in the regulatory region of the Il4 gene. |
| Q33987889 | IgE regulates T helper cell differentiation through FcgammaRIII mediated dendritic cell cytokine modulation. |
| Q51593223 | Impaired IL-4 production by CD8+ T cells in NOD mice is related to a defect of c-Maf binding to the IL-4 promoter. |
| Q37179927 | Impaired secretion of interferons by dendritic cells from aged subjects to influenza : role of histone modifications |
| Q36890824 | In utero supplementation with methyl donors enhances allergic airway disease in mice |
| Q37194984 | In vitro and in vivo differentiated effector CD8 T cells display divergent histone acetylation patterns within the Ifng locus |
| Q51977261 | Induction of a Th1 response from Th2-polarized T cells by activated dendritic cells: dependence on TCR:peptide-MHC interaction, ICAM-1, IL-12, and IFN-gamma. |
| Q51999239 | Interleukin (IL)-4-independent maintenance of histone modification of the IL-4 gene loci in memory Th2 cells. |
| Q28291383 | Interleukin-12-induced interferon-gamma production by human peripheral blood T cells is regulated by mammalian target of rapamycin (mTOR) |
| Q34003618 | Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells |
| Q41643177 | Janus-kinase-3-dependent signals induce chromatin remodeling at the Ifng locus during T helper 1 cell differentiation |
| Q36853486 | Kinetic analysis of genomewide gene expression reveals molecule circuitries that control T cell activation and Th1/2 differentiation |
| Q36956614 | Lck mediates Th2 differentiation through effects on T-bet and GATA-3. |
| Q36602302 | Long-range histone acetylation of the Ifng gene is an essential feature of T cell differentiation |
| Q80587027 | Long-range intrachromosomal interactions in the T helper type 2 cytokine locus |
| Q24289144 | MHC class II transactivator represses human IL-4 gene transcription by interruption of promoter binding with CBP/p300, STAT6 and NFAT1 via histone hypoacetylation |
| Q41486650 | Marijuana-derived Δ-9-tetrahydrocannabinol suppresses Th1/Th17 cell-mediated delayed-type hypersensitivity through microRNA regulation |
| Q34663764 | Maternal allergy increases susceptibility to offspring allergy in association with TH2-biased epigenetic alterations in a mouse model of peanut allergy |
| Q37849185 | Maternal signals for progeny prevention against allergy and asthma |
| Q40687886 | Memory and flexibility of cytokine gene expression as separable properties of human T(H)1 and T(H)2 lymphocytes |
| Q38044664 | Metabolic checkpoints in activated T cells |
| Q35571270 | Methylation and demethylation in the regulation of genes, cells, and responses in the immune system |
| Q37619398 | Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: a target for STAT6 but not GATA3. |
| Q37802429 | Molecular mechanisms by which T‐bet regulates T‐helper cell commitment |
| Q37864696 | Molecular mechanisms of T-cell tolerance. |
| Q44411465 | Murine Neonatal Lymphocytes Show Rapid Early Cell Cycle Entry and Cell Division |
| Q41444445 | Murine neonatal CD4+ cells are poised for rapid Th2 effector-like function |
| Q37417983 | Natural indoles, indole-3-carbinol and 3,3'-diindolymethane, inhibit T cell activation by staphylococcal enterotoxin B through epigenetic regulation involving HDAC expression |
| Q50989710 | Nuclear repositioning marks the selective exclusion of lineage-inappropriate transcription factor loci during T helper cell differentiation. |
| Q35641142 | Opposing roles of NF-kappaB family members in the regulation of NK cell proliferation and production of IFN-gamma |
| Q42151373 | Permission to proceed: Jak3 and STAT5 signaling molecules give the green light for T helper 1 cell differentiation |
| Q92051388 | Polycomb repressive complex 2 is a critical mediator of allergic inflammation |
| Q44771099 | Probabilistic regulation of IL-4 production in Th2 cells: accessibility at the Il4 locus |
| Q34122195 | Quantitative proteomics analysis of the nuclear fraction of human CD4+ cells in the early phases of IL-4-induced Th2 differentiation |
| Q34628368 | Rapamycin-sensitive signals control TCR/CD28-driven Ifng, Il4 and Foxp3 transcription and promoter region methylation |
| Q41105296 | Recombinant Leishmania major lipophosphoglycan 3 activates human T-lymphocytes via TLR2-independent pathway |
| Q28256001 | Regulation of interferon-gamma during innate and adaptive immune responses |
| Q73691201 | Regulation of the Th2 cytokine locus by a locus control region |
| Q39368352 | Repression of interleukin-5 transcription by the glucocorticoid receptor targets GATA3 signaling and involves histone deacetylase recruitment |
| Q59645294 | Role of Environmental Epigenetics in Perinatal and Neonatal Development |
| Q37864686 | Role of immune responses in the pathogenesis of low-risk MDS and high-risk MDS: implications for immunotherapy |
| Q45944230 | SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes. |
| Q33756678 | Self-antigen prevents CD8 T cell effector differentiation by CD134 and CD137 dual costimulation |
| Q38771066 | Sensitivity and resistance to regulation by IL-4 during Th17 maturation |
| Q37400372 | Signal transducer and activator of transcription 4 is required for the transcription factor T-bet to promote T helper 1 cell-fate determination |
| Q57054689 | Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells |
| Q37367853 | Signal transduction and Th17 cell differentiation |
| Q36571580 | Signal transduction pathways and transcriptional regulation in the control of Th17 differentiation |
| Q35951819 | Signaling by IL-12 and IL-23 and the immunoregulatory roles of STAT4. |
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| Q33756668 | T-bet down-modulation in tolerized Th1 effector CD4 cells confers a TCR-distal signaling defect that selectively impairs IFN-gamma expression |
| Q36228437 | T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription |
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