Breast cancer: coordinated regulation of CCL2 secretion by intracellular glycosaminoglycans and chemokine motifs

scientific article

Breast cancer: coordinated regulation of CCL2 secretion by intracellular glycosaminoglycans and chemokine motifs is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.NEO.2014.08.004
P932PMC publication ID4234876
P698PubMed publication ID25246273
P5875ResearchGate publication ID265854306

P2093author name stringAdva Yeheskel
Adit Ben-Baruch
Tsipi Meshel
Elad Mamon
Gali Soria
Yaeli Lebel-Haziv
P2860cites workLocalization of osteoblast inflammatory cytokines MCP-1 and VEGF to the matrix of the trabecula of the femur, a target area for metastatic breast cancer cell colonizationQ46911164
Glycosylation enhances functional stability of the chemotactic cytokine CCL2.Q54519045
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Expression of CCR2 by endothelial cells : implications for MCP-1 mediated wound injury repair and In vivo inflammatory activation of endotheliumQ78233810
CCL2/CCR2 pathway mediates recruitment of myeloid suppressor cells to cancersQ79674004
Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instabilityQ22242922
Heparanase uptake is mediated by cell membrane heparan sulfate proteoglycansQ24300477
MolProbity: all-atom contacts and structure validation for proteins and nucleic acidsQ24684673
The structure of MCP-1 in two crystal forms provides a rare example of variable quaternary interactionsQ27734322
Immunity, Inflammation, and CancerQ27861048
Monocyte chemotactic protein (MCP)-1 promotes angiogenesis via a novel transcription factor, MCP-1-induced protein (MCPIP)Q28115465
The BBXB motif of RANTES is the principal site for heparin binding and controls receptor selectivityQ28140341
CCL2 (Monocyte Chemoattractant Protein-1) in cancer bone metastasesQ28278260
Animal cell mutants defective in glycosaminoglycan biosynthesisQ28305815
Ethanol promotes mammary tumor growth and angiogenesis: the involvement of chemoattractant factor MCP-1Q28383305
The role of myeloid cells in the promotion of tumour angiogenesisQ29614299
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasisQ29614347
Protein structure prediction using RosettaQ29616386
Accessories to the crime: functions of cells recruited to the tumor microenvironmentQ29620161
Loss of transforming growth factor-beta signaling in mammary fibroblasts enhances CCL2 secretion to promote mammary tumor progression through macrophage-dependent and -independent mechanismsQ30436152
Chemokines as mediators of neovascularizationQ30438032
Heparan sulfate biosynthesis: methods for investigation of the heparanosomeQ31085481
Evidence for a granule targeting sequence within platelet factor 4.Q33217394
Cathepsin G-mediated enhanced TGF-beta signaling promotes angiogenesis via upregulation of VEGF and MCP-1.Q33625023
MCP-1: chemoattractant with a role beyond immunity: a reviewQ33633544
Identification of residues in the monocyte chemotactic protein-1 that contact the MCP-1 receptor, CCR2.Q33877707
Luminal and basal-like breast cancer cells show increased migration induced by hypoxia, mediated by an autocrine mechanism.Q33887570
Transactivation of MCP-1/CCL2 by beta-catenin/TCF-4 in human breast cancer cellsQ34249533
Monocyte chemoattractant protein-1/CCL2 produced by stromal cells promotes lung metastasis of 4T1 murine breast cancer cellsQ34634293
Inflammatory mediators in breast cancer: coordinated expression of TNFα & IL-1β with CCL2 & CCL5 and effects on epithelial-to-mesenchymal transitionQ34984217
Chemokine (C-C motif) ligand 2 mediates the prometastatic effect of dysadherin in human breast cancer cellsQ35011812
Heparan sulfate proteoglycansQ35059448
Cell-surface heparan sulfate proteoglycans are essential components of the unconventional export machinery of FGF-2Q35108285
Intracellular proteoglycansQ35647324
Oestrogen receptor negative breast cancers exhibit high cytokine contentQ35749364
Mechanisms regulating the secretion of the promalignancy chemokine CCL5 by breast tumor cells: CCL5's 40s loop and intracellular glycosaminoglycansQ35763876
CCL2 (monocyte chemoattractant protein-1) and cancerQ35832328
Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistanceQ35903509
Interaction of chemokines and glycosaminoglycans: a new twist in the regulation of chemokine function with opportunities for therapeutic interventionQ36180251
The biological relevance of chemokine-proteoglycan interactionsQ36482111
Twist1 induces CCL2 and recruits macrophages to promote angiogenesisQ36594566
Human xylosyltransferases in health and diseaseQ36792984
miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasisQ36902134
The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophagesQ36959353
Heparan sulphate biosynthesis and diseaseQ37119533
The inflammatory chemokines CCL2 and CCL5 in breast cancerQ37148637
Obesity promotes breast cancer by CCL2-mediated macrophage recruitment and angiogenesisQ37298848
Molecular requirements for sorting of the chemokine interleukin-8/CXCL8 to endothelial Weibel-Palade bodiesQ37358141
Chemokine (C-C motif) ligand 2 engages CCR2+ stromal cells of monocytic origin to promote breast cancer metastasis to lung and boneQ37431256
Chemokine oligomerization and interactions with receptors and glycosaminoglycans: the role of structural dynamics in functionQ37827607
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Pathological and epidemiological factors associated with advanced stage at diagnosis of breast cancerQ38032111
Vascular permeability changes involved in tumor metastasisQ38090248
Inflammatory chemokines and metastasis--tracing the accessoryQ38121413
Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1: implications for structure and function in vivo.Q38343397
Concomitant expression of the chemokines RANTES and MCP-1 in human breast cancer: a basis for tumor-promoting interactions.Q39940205
Metastatic breast cancer induces an osteoblast inflammatory responseQ40058584
Chemokine stimulation of monocyte matrix metalloproteinase-9 requires endogenous TNF-alphaQ40754434
Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progressionQ40868885
Chemokines induce the cellular migration of MCF-7 human breast carcinoma cells: subpopulations of tumour cells display positive and negative chemotaxis and differential in vivo growth potentialsQ40903938
Lysine 58 and histidine 66 at the C-terminal alpha-helix of monocyte chemoattractant protein-1 are essential for glycosaminoglycan bindingQ40999171
Beta-chemokines are released from HIV-1-specific cytolytic T-cell granules complexed to proteoglycansQ41060711
Full active baculovirus-expressed human monocyte chemoattractant protein 1 with the intact N-terminusQ42067004
CCL2 at the crossroad of cancer metastasisQ42136303
Serglycin Is a Major Proteoglycan in Polarized Human Endothelial Cells and Is Implicated in the Secretion of the Chemokine GROα/CXCL1Q42576979
Structural and functional analysis of the RANTES-glycosaminoglycans interactionsQ43616295
Important role of heparan sulfate in postnatal islet growth and insulin secretionQ46066878
P4510describes a project that usesImageJQ1659584
P433issue9
P304page(s)723-740
P577publication date2014-09-01
P1433published inNeoplasiaQ2962042
P1476titleBreast cancer: coordinated regulation of CCL2 secretion by intracellular glycosaminoglycans and chemokine motifs
P478volume16

Reverse relations

cites work (P2860)
Q35528569Chemokine and chemokine receptor structure and interactions: implications for therapeutic strategies
Q89629028MicroRNA-155 governs SHIP-1 expression and localization in NK cells and regulates subsequent infiltration into murine AT3 mammary carcinoma
Q38678399The sweet spot: how GAGs help chemokines guide migrating cells
Q35723824Visfatin Mediates SCLC Cells Migration across Brain Endothelial Cells through Upregulation of CCL2

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