Serum response factor utilizes distinct promoter- and enhancer-based mechanisms to regulate cytoskeletal gene expression in macrophages

scientific article

Serum response factor utilizes distinct promoter- and enhancer-based mechanisms to regulate cytoskeletal gene expression in macrophages is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.00836-10
P932PMC publication ID3028656
P698PubMed publication ID21135125
P5875ResearchGate publication ID49661641

P50authorSven HeinzQ39512651
Christopher K GlassQ55458945
P2093author name stringJoseph M Miano
Christopher Benner
Amy L Sullivan
Lan Xie
Wendy Huang
P2860cites workIdentification and characterization of novel human tissue-specific RFX transcription factorsQ21093412
BioGPS: an extensible and customizable portal for querying and organizing gene annotation resourcesQ21183895
Megakaryoblastic Leukemia-1/2, a Transcriptional Co-activator of Serum Response Factor, Is Required for Skeletal Myogenic DifferentiationQ24297992
Potentiation of serum response factor activity by a family of myocardin-related transcription factorsQ24313025
Spatial flexibility in ternary complexes between SRF and its accessory proteinsQ24555659
Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in miceQ24557452
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identitiesQ24617969
Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammalsQ24630840
Expression analysis of G Protein-Coupled Receptors in mouse macrophagesQ24650905
Serum response factor: master regulator of the actin cytoskeleton and contractile apparatusQ36575149
Leukocyte-specific protein 1 (LSP1): a regulator of leukocyte emigration in inflammationQ36604768
Trophic macrophages in development and diseaseQ36829147
A glimpse into the epigenetic landscape of gene regulationQ37092827
Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neuronsQ37209812
A myocardin-related transcription factor regulates activity of serum response factor in DrosophilaQ37493988
Serum response factor is required for immediate-early gene activation yet is dispensable for proliferation of embryonic stem cellsQ38302355
The transcription factors Elk-1 and serum response factor interact by direct protein-protein contacts mediated by a short region of Elk-1.Q38308517
MyoD distal regulatory region contains an SRF binding CArG element required for MyoD expression in skeletal myoblasts and during muscle regeneration.Q38353674
Serum response factor: transcriptional regulation of genes induced by growth factors and differentiation.Q40455362
SRF mediates activity-induced gene expression and synaptic plasticity but not neuronal viabilityQ42477944
Expression of the serum response factor gene is regulated by serum response factor binding sitesQ42811052
Transcriptional repression mediated by the serum response factor.Q42830832
Serum response factor is crucial for actin cytoskeletal organization and focal adhesion assembly in embryonic stem cellsQ42918539
Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages.Q43141233
The correlations of the function and positional distribution of the cis-elements CArG around the TSS in the genes of Mus musculus.Q51806873
Multilineage transcriptional priming and determination of alternate hematopoietic cell fates.Q51934822
Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates.Q52112384
Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factorsQ58485006
Exploring the full spectrum of macrophage activationQ24653754
The human genome browser at UCSCQ24672361
Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genesQ24682874
DAVID: Database for Annotation, Visualization, and Integrated DiscoveryQ27499374
Fitting a mixture model by expectation maximization to discover motifs in biopolymersQ27860556
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genomeQ28131828
Histone modifications at human enhancers reflect global cell-type-specific gene expressionQ28238467
Evidence for serum response factor-mediated regulatory networks governing SM22alpha transcription in smooth, skeletal, and cardiac muscle cellsQ28245057
Human plastin genes. Comparative gene structure, chromosome location, and differential expression in normal and neoplastic cellsQ28265782
Serum response factor is essential for mesoderm formation during mouse embryogenesisQ28505560
Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4Q28508228
Identification of a novel transcriptional activator, BSAC, by a functional cloning to inhibit tumor necrosis factor-induced cell deathQ28510888
Restricted inactivation of serum response factor to the cardiovascular systemQ28512435
Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targetsQ28513648
Neuronal migration in the murine rostral migratory stream requires serum response factorQ28585328
Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factorQ28587239
Targeted inactivation of serum response factor in the developing heart results in myocardial defects and embryonic lethalityQ28589037
Srf(-/-) ES cells display non-cell-autonomous impairment in mesodermal differentiationQ28589471
The transcription factor Srf regulates hematopoietic stem cell adhesionQ28590745
Role of H2-calponin in regulating macrophage motility and phagocytosisQ28592790
Actin dynamics control SRF activity by regulation of its coactivator MALQ28646140
Widespread transcription at neuronal activity-regulated enhancersQ29614330
Inducible gene targeting in miceQ29614544
GREAT improves functional interpretation of cis-regulatory regionsQ29614846
Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencingQ29618021
The transcription factor regulatory factor X1 increases the expression of neuronal glutamate transporter type 3.Q30440563
Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apoptosisQ33581637
A coat protein on phagosomes involved in the intracellular survival of mycobacteriaQ33862936
Genome-wide analysis of ETS-family DNA-binding in vitro and in vivoQ34000149
Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression.Q34304925
The MADS-box family of transcription factorsQ34310228
Defining the mammalian CArGomeQ34338820
FLI1 and EWS-FLI1 function as ternary complex factors and ELK1 and SAP1a function as ternary and quaternary complex factors on the Egr1 promoter serum response elementsQ34414582
Serum response factor: toggling between disparate programs of gene expressionQ35146145
Plastins: versatile modulators of actin organization in (patho)physiological cellular processesQ36165372
P4510describes a project that usesImageJQ1659584
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectcytoskeletonQ154626
P304page(s)861-875
P577publication date2010-12-06
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleSerum response factor utilizes distinct promoter- and enhancer-based mechanisms to regulate cytoskeletal gene expression in macrophages
P478volume31

Reverse relations

cites work (P2860)
Q64911551A β2-Integrin/MRTF-A/SRF Pathway Regulates Dendritic Cell Gene Expression, Adhesion, and Traction Force Generation.
Q100503778AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma
Q36298256Analysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease.
Q37065350Androgen-responsive serum response factor target genes regulate prostate cancer cell migration.
Q92642022CREB Promotes Beta Cell Gene Expression by Targeting Its Coactivators to Tissue-Specific Enhancers
Q39291348Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20.
Q52722330DP1 receptor signaling prevents the onset of intrinsic apoptosis in eosinophils and functions as a transcriptional modulator.
Q34270499ELK1 uses different DNA binding modes to regulate functionally distinct classes of target genes
Q38696838EWS-FLI1 perturbs MRTFB/YAP-1/TEAD target gene regulation inhibiting cytoskeletal autoregulatory feedback in Ewing sarcoma
Q41901163Epigenetic dynamics of monocyte-to-macrophage differentiation
Q35624730Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation.
Q35233885Identifying functional single nucleotide polymorphisms in the human CArGome
Q90333330Inferring the Molecular Mechanisms of Noncoding Alzheimer's Disease-Associated Genetic Variants
Q36040281Interferon-induced mechanosensing defects impede apoptotic cell clearance in lupus
Q35139962LMO7 mediates cell-specific activation of the Rho-myocardin-related transcription factor-serum response factor pathway and plays an important role in breast cancer cell migration
Q92239668MADS-Box Genes Are Key Components of Genetic Regulatory Networks Involved in Abiotic Stress and Plastic Developmental Responses in Plants
Q33622359MKL1/2 and ELK4 co-regulate distinct serum response factor (SRF) transcription programs in macrophages
Q35103545MRTF-SRF signaling is required for seeding of HSC/Ps in bone marrow during development
Q48106107Noncanonical hedgehog pathway activation through SRF-MKL1 promotes drug resistance in basal cell carcinomas
Q34579722Optimization of transcription factor binding map accuracy utilizing knockout-mouse models
Q34545552Regulation of inflammatory phenotype in macrophages by a diabetes-induced long noncoding RNA.
Q34265770Rev-erbα and Rev-erbβ coordinately protect the circadian clock and normal metabolic function
Q39526299Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts
Q33585299SRF is required for neutrophil migration in response to inflammation
Q42550359SRF regulates craniofacial development through selective recruitment of MRTF cofactors by PDGF signaling.
Q41831362Serum response factor indirectly regulates type I interferon-signaling in macrophages
Q57804811Spatial confinement downsizes the inflammatory response of macrophages
Q36305651Spi-1/PU.1 activates transcription through clustered DNA occupancy in erythroleukemia
Q42174811The MADS Symphonies of Transcriptional Regulation.
Q26998761The regulatory role of serum response factor pathway in neutrophil inflammatory response
Q28081960The selection and function of cell type-specific enhancers
Q28080857The short and long of noncoding sequences in the control of vascular cell phenotypes
Q27001970Towards an understanding of cell-specific functions of signal-dependent transcription factors

Search more.