Mucin-interacting proteins: from function to therapeutics

scientific article

Mucin-interacting proteins: from function to therapeutics is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.TIBS.2009.10.003
P932PMC publication ID3030310
P698PubMed publication ID19913432
P5875ResearchGate publication ID38089408

P2093author name stringSurinder K Batra
Shantibhusan Senapati
Srustidhar Das
P2860cites workHuman MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress responseQ24294875
MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damageQ24298896
The C-terminus of the transmembrane mucin MUC17 binds to the scaffold protein PDZK1 that stably localizes it to the enterocyte apical membrane in the small intestineQ24299903
MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of metQ24301503
Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesionQ24301956
Two-hybrid analysis of human salivary mucin MUC7 interactionsQ24337527
Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-cateninQ24522854
MUC4 mucin interacts with and stabilizes the HER2 oncoprotein in human pancreatic cancer cellsQ24630950
Association of cell surface mucins with galectin-3 contributes to the ocular surface epithelial barrierQ24658379
A binding domain on mesothelin for CA125/MUC16Q24658397
Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumorsQ24673454
Molecular mapping of statherin- and histatin-binding domains in human salivary mucin MG1 (MUC5B) by the yeast two-hybrid systemQ28139450
The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3 beta and beta-cateninQ28142359
MUC1 alters beta-catenin-dependent tumor formation and promotes cellular invasionQ28180863
Heregulin targets gamma-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 oncoproteinQ28203511
DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7Q28204499
MG2 and lactoferrin form a heterotypic complex in salivary secretionsQ28206394
Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary glandQ28208406
Structure and biosynthesis of human salivary mucinsQ28216868
Mucins in cancer: protection and control of the cell surfaceQ28235006
Human salivary mucin MG1 selectively forms heterotypic complexes with amylase, proline-rich proteins, statherin, and histatinsQ28235421
Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesionQ28237260
Cell surface-associated mucins in signal transductionQ28257314
MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90Q28271920
Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange proteinQ28296763
An intramembrane modulator of the ErbB2 receptor tyrosine kinase that potentiates neuregulin signalingQ28582768
MUC1 synthetic peptide inhibition of intercellular adhesion molecule-1 and MUC1 binding requires six tandem repeats.Q31956559
The cancer antigen CA125 represents a novel counter receptor for galectin-1.Q34181115
Cloning of partial cDNA encoding differentiation and tumor-associated mucin glycoproteins expressed by human mammary epitheliumQ34341950
MUC1 oncoprotein activates the IkappaB kinase beta complex and constitutive NF-kappaB signallingQ34407038
Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agentsQ34440814
The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loopQ34440854
MUC1 is a novel regulator of ErbB1 receptor traffickingQ34571022
MUC1 oncoprotein functions in activation of fibroblast growth factor receptor signalingQ34572658
Functions of MUC16 in corneal epithelial cellsQ34693932
Gel-forming mucins appeared early in metazoan evolution.Q36092589
Intracellular MUC1 peptides inhibit cancer progressionQ37178708
The cytoplasmic tail of MUC1: a very busy placeQ37210822
The MUC gene family: their role in the diagnosis and prognosis of gastric cancerQ37284927
Direct targeting of the mucin 1 oncoprotein blocks survival and tumorigenicity of human breast carcinoma cellsQ37290260
Clinical potential of mucins in diagnosis, prognosis, and therapy of ovarian cancer.Q37326840
Galectin-3 interaction with Thomsen-Friedenreich disaccharide on cancer-associated MUC1 causes increased cancer cell endothelial adhesion.Q38307814
Development and in vitro validation of anti-mesothelin biobodies that prevent CA125/Mesothelin-dependent cell attachmentQ39800430
Phosphorylation of MUC1 by Met modulates interaction with p53 and MMP1 expressionQ39961616
Platelet-derived growth factor receptor beta-mediated phosphorylation of MUC1 enhances invasiveness in pancreatic adenocarcinoma cellsQ40124709
Nuclear import of the MUC1-C oncoprotein is mediated by nucleoporin Nup62.Q40133198
MUC1 oncoprotein stabilizes and activates estrogen receptor alphaQ40326798
MUC1 mediates transendothelial migration in vitro by ligating endothelial cell ICAM-1.Q40345482
MUC1 (CD227) interacts with lck tyrosine kinase in Jurkat lymphoma cells and normal T cellsQ40498647
MUC1 initiates a calcium signal after ligation by intercellular adhesion molecule-1.Q40550805
MUC1 can interact with adenomatous polyposis coli in breast cancerQ40578624
Structure, biosynthesis, and function of salivary mucinsQ40585561
Interaction of human MUC1 and beta-catenin is regulated by Lck and ZAP-70 in activated Jurkat T cellsQ40591851
Involvement of the MAP kinase ERK2 in MUC1 mucin signalingQ40798915
Structural features of salivary functionQ40847177
Isolation and physical characterization of the MUC7 (MG2) mucin from saliva: evidence for self-association.Q42991565
MUC1 overexpression results in mammary gland tumorigenesis and prolonged alveolar differentiationQ47281356
The role of Thomsen-Friedenreich antigen in adhesion of human breast and prostate cancer cells to the endothelium.Q52543238
MUC1 mucin core protein binds to the domain 1 of ICAM-1.Q52828650
The breast mucin MUCI as a novel adhesion ligand for endothelial intercellular adhesion molecule 1 in breast cancerQ71513108
Peritoneal natural killer cells from epithelial ovarian cancer patients show an altered phenotype and bind to the tumour marker MUC16 (CA125)Q80580929
Transforming growth factor alpha dependent cancer progression is modulated by Muc1Q80635833
Muc1 affects c-Src signaling in PyV MT-induced mammary tumorigenesisQ81753531
P433issue4
P407language of work or nameEnglishQ1860
P1104number of pages10
P304page(s)236-245
P577publication date2009-11-11
P1433published inTrends in Biochemical SciencesQ1565711
P1476titleMucin-interacting proteins: from function to therapeutics
P478volume35

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cites work (P2860)
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Q47410775Anti-cancer effects of F16: A novel vascular endothelial growth factor receptor-specific inhibitor
Q35853834Autophagy is decreased in triple-negative breast carcinoma involving likely the MUC1-EGFR-NEU1 signalling pathway.
Q36283550Binding of Galectin-3, a β-Galactoside-binding Lectin, to MUC1 Protein Enhances Phosphorylation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) and Akt, Promoting Tumor Cell Malignancy
Q36827374Binding of transmembrane mucins to galectin-3 limits herpesvirus 1 infection of human corneal keratinocytes.
Q38908575Carboxyl-terminal domain of MUC16 imparts tumorigenic and metastatic functions through nuclear translocation of JAK2 to pancreatic cancer cells.
Q37706759Cell membrane-anchored MUC4 promotes tumorigenicity in epithelial carcinomas
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Q37520973MUC13 interaction with receptor tyrosine kinase HER2 drives pancreatic ductal adenocarcinoma progression
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Q59130268Probing into the Interaction of Nicotine and Bovine Submaxillary Mucin: NMR, Fluorescence, and FTIR Approaches
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Q35846840Silver nanoparticles modify VEGF signaling pathway and mucus hypersecretion in allergic airway inflammation
Q59103157Specific MUC1 Splice Variants Are Correlated With Tumor Progression in Esophageal Cancer
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Q38922649Suppression of Toll-like receptor-mediated innate immune responses at the ocular surface by the membrane-associated mucins MUC1 and MUC16
Q35741633Targeting EGF-receptor(s) - STAT1 axis attenuates tumor growth and metastasis through downregulation of MUC4 mucin in human pancreatic cancer
Q58726271The Impact of Mesothelin in the Ovarian Cancer Tumor Microenvironment
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Q55374172Triple-negative and HER2-overexpressing breast cancer cell sialylation impacts tumor microenvironment T-lymphocyte subset recruitment: a possible mechanism of tumor escape.
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