Transferrin is a major determinant of hepcidin expression in hypotransferrinemic mice

scientific article

Transferrin is a major determinant of hepcidin expression in hypotransferrinemic mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2010-05-287359
P932PMC publication ID3031485
P698PubMed publication ID20956801

P50authorNancy AndrewsQ4793337
Mark D FlemingQ57330225
P2093author name stringThomas B Bartnikas
P2860cites workRegulation of transferrin receptor 2 protein levels by transferrinQ24301632
Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic diseaseQ28209487
Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liverQ28506594
Lack of the bone morphogenetic protein BMP6 induces massive iron overloadQ28510138
Iron Loading and Overloading due to Ineffective ErythropoiesisQ33844026
The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivoQ33883160
Regulators of iron balance in humansQ34060240
Tissue distribution and clearance kinetics of non-transferrin-bound iron in the hypotransferrinemic mouse: a rodent model for hemochromatosisQ34625175
Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expressionQ34658174
Suppression of hepcidin during anemia requires erythropoietic activityQ35848905
Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4.Q35990728
The transferrin receptor modulates Hfe-dependent regulation of hepcidin expressionQ36539421
Transferrin-a modulates hepcidin expression in zebrafish embryosQ37142191
Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytesQ37207754
Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cellsQ37262477
The regulation of hepcidin and its effects on systemic and cellular iron metabolism.Q37346708
Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosisQ37376502
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolismQ41871982
Transferrin therapy ameliorates disease in beta-thalassemic mice.Q50586962
BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression.Q54472480
Effects of plasma transfusion on hepcidin production in human congenital hypotransferrinemiaQ56490107
High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidinQ56490134
Iron absorption in hypotransferrinemic miceQ67760881
Importance of anemia and transferrin levels in the regulation of intestinal iron absorption in hypotransferrinemic miceQ73168671
The molecular defect in hypotransferrinemic miceQ74055142
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)630-637
P577publication date2010-10-18
P1433published inBloodQ885070
P1476titleTransferrin is a major determinant of hepcidin expression in hypotransferrinemic mice
P478volume117

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