Effect of genetic and pharmacological blockade of GABA receptors on the 5-HT2C receptor function during stress

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Effect of genetic and pharmacological blockade of GABA receptors on the 5-HT2C receptor function during stress is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/JNC.12929
P932PMC publication ID4237664
P698PubMed publication ID25113583
P5875ResearchGate publication ID264675654

P50authorMartin GassmannQ42678150
Bernhard BettlerQ87096813
P2093author name stringLaurence Lanfumey
Raymond Mongeau
Uwe Rudolph
Michel Hamon
Caroline Chevarin
Cédric B P Martin
P2860cites workSerotonin activates the hypothalamic-pituitary-adrenal axis via serotonin 2C receptor stimulationQ28307689
In vivo evidence that 5-HT(2C) receptors inhibit 5-HT neuronal activity via a GABAergic mechanismQ28565374
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Five subtypes of type A gamma-aminobutyric acid receptors identified in neurons by double and triple immunofluorescence staining with subunit-specific antibodiesQ30983895
5-HT(2C) receptors localize to dopamine and GABA neurons in the rat mesoaccumbens pathwayQ33936895
Serotonin2C receptor localization in GABA neurons of the rat medial prefrontal cortex: implications for understanding the neurobiology of addictionQ34032951
GABA-based therapeutic approaches: GABAA receptor subtype functionsQ34479365
Selective activation of 5-HT(2C) receptors stimulates GABA-ergic function in the rat substantia nigra pars reticulata: a combined in vivo electrophysiological and neurochemical studyQ34653201
Differential compartmentalization and distinct functions of GABAB receptor variantsQ36492579
Differential expression of 5HT-1A, alpha 1b adrenergic, CRF-R1, and CRF-R2 receptor mRNA in serotonergic, gamma-aminobutyric acidergic, and catecholaminergic cells of the rat dorsal raphe nucleus.Q36726952
Neuron-specific expression of GABAA-receptor subtypes: differential association of the alpha 1- and alpha 3-subunits with serotonergic and GABAergic neuronsQ36771916
Restraint stress increases serotonin release in the central nucleus of the amygdala via activation of corticotropin-releasing factor receptorsQ36776225
Further pharmacological characterization of 5-HT(2C) receptor agonist-induced inhibition of 5-HT neuronal activity in the dorsal raphe nucleus in vivoQ37481197
Regulation of neuronal GABA(B) receptor functions by subunit compositionQ38010955
Controversies on the role of 5-HT(2C) receptors in the mechanisms of action of antidepressant drugsQ38196162
Clozapine and haloperidol differently suppress the MK-801-increased glutamatergic and serotonergic transmission in the medial prefrontal cortex of the rat.Q42171479
Effects of GABA-ergic drugs on penile erection induced by apomorphine in ratsQ42280894
GABA(A) receptor modulation of 5-HT neuronal firing in the median raphe nucleus: implications for the action of anxiolyticsQ42491926
GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain.Q42497057
Differential regulation of 5-hydroxytryptamine release by GABAA and GABAB receptors in midbrain raphe nuclei and forebrain of ratsQ42581383
5-HT2C receptor activation prevents stress-induced enhancement of brain 5-HT turnover and extracellular levels in the mouse brain: modulation by chronic paroxetine treatmentQ42925027
Strain-dependent serotonin neuron feedback control: role of serotonin 2C receptorsQ43003243
Prefrontal cortical projections to the rat dorsal raphe nucleus: ultrastructural features and associations with serotonin and gamma-aminobutyric acid neuronsQ44702188
Expression of serotonin 5-HT2C receptors in GABAergic cells of the anterior raphe nucleiQ45225824
GABAergic antagonist blocks the reduction of tonic immobility behavior induced by activation of 5-HT2 receptors in the basolateral nucleus of the amygdala in guinea pigs.Q46021635
Tonic inhibition in principal cells of the amygdala: a central role for α3 subunit-containing GABAA receptorsQ46746864
Evidence for a significant role of alpha 3-containing GABAA receptors in mediating the anxiolytic effects of benzodiazepines.Q46807874
Augmentation of SSRI effects on serotonin by 5-HT2C antagonists: mechanistic studies.Q48319504
Serotonin (5-HT)2C receptors tonically inhibit dopamine (DA) and noradrenaline (NA), but not 5-HT, release in the frontal cortex in vivoQ48374845
Serotonin-2A receptor regulation of panic-like behavior in the rat dorsal periaqueductal gray matter: the role of GABA.Q50624981
Effects of RO 60 0175, a 5-HT(2C) receptor agonist, in three animal models of anxiety.Q51083229
GABAergic influences on plus-maze behaviour in mice.Q51555878
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)566-572
P577publication date2014-09-04
P1433published inJournal of NeurochemistryQ6295643
P1476titleEffect of genetic and pharmacological blockade of GABA receptors on the 5-HT2C receptor function during stress
P478volume131

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cites work (P2860)
Q47709211Constitutive activity of 5-HT2C receptors is present after incomplete spinal cord injury but is not modified after chronic SSRI or baclofen treatment
Q41928667Effects of GABAa receptor antagonists on motor behavior in pharmacological Parkinson's disease model in mice.

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