| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Mohammed Abdelsaid | Q60977040 |
| P2093 | author name string | Azza B El-Remessy | |
| Mohammed Mh Al-Gayyar | |||
| Bilal K Yousufzai | |||
| Will Whitmire | |||
| P2860 | cites work | VEGF-B inhibits apoptosis via VEGFR-1-mediated suppression of the expression of BH3-only protein genes in mice and rats | Q24312100 |
| Neuroprotection of insulin against oxidative stress-induced apoptosis in cultured retinal neurons: involvement of phosphoinositide 3-kinase/Akt signal pathway | Q24316173 | ||
| VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis | Q24658393 | ||
| Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells | Q24679724 | ||
| The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group | Q27861088 | ||
| Regulation of cell survival by secreted proneurotrophins | Q27919620 | ||
| PEDF: a multifaceted neurotrophic factor | Q28191537 | ||
| Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth | Q28203972 | ||
| Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor | Q28212153 | ||
| The retinal proteome in experimental diabetic retinopathy: up-regulation of crystallins and reversal by systemic and periocular insulin | Q28388205 | ||
| Ranibizumab for neovascular age-related macular degeneration | Q29617549 | ||
| Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy | Q30837772 | ||
| Insulin promotes rat retinal neuronal cell survival in a p70S6K-dependent manner | Q33195730 | ||
| Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors | Q33382103 | ||
| Early intervention of tyrosine nitration prevents vaso-obliteration and neovascularization in ischemic retinopathy | Q33509477 | ||
| Neurodegenerative influence of oxidative stress in the retina of a murine model of diabetes | Q33773287 | ||
| Autocrine/paracrine role of insulin-related growth factors in neurogenesis: local expression and effects on cell proliferation and differentiation in retina | Q33873341 | ||
| Vitreous levels of the insulin-like growth factors I and II, and the insulin-like growth factor binding proteins 2 and 3, increase in neovascular eye disease. Studies in nondiabetic and diabetic subjects | Q33909613 | ||
| Pigment epithelium-derived factor delays the death of photoreceptors in mouse models of inherited retinal degenerations | Q73277924 | ||
| Insulin-like growth factor-I protects axotomized rat retinal ganglion cells from secondary death via PI3-K-dependent Akt phosphorylation and inhibition of caspase-3 In vivo | Q73348014 | ||
| Therapeutic prospects for PEDF: more than a promising angiogenesis inhibitor | Q73580422 | ||
| Effect of streptozotocin-induced diabetes on NGF, P75(NTR) and TrkA content of prevertebral and paravertebral rat sympathetic ganglia | Q73850621 | ||
| Patterns of quantitative sensation testing of hypoesthesia and hyperalgesia are predictive of diabetic polyneuropathy: a study of three cohorts. Nerve growth factor study group | Q73905002 | ||
| Müller cell changes in human diabetic retinopathy | Q74371192 | ||
| Insulin-related growth factors stimulate proliferation of retinal progenitors in the goldfish | Q74525346 | ||
| The role of neuronal growth factors in neurodegenerative disorders of the human brain | Q74697359 | ||
| Increased nerve growth factor mRNA in lateral calf skin biopsies from diabetic patients | Q77403153 | ||
| Diabetic retinopathy | Q79113458 | ||
| Diabetic retinopathy | Q79352629 | ||
| Systemic IGF-I treatment inhibits cell death in diabetic rat retina | Q83188959 | ||
| Control of Müller glial cell proliferation and activation following retinal injury. | Q55034188 | ||
| An overview of the eye in diabetes. | Q55434661 | ||
| Study of ischeamic heart disease in young women | Q70705876 | ||
| The value of the oscillatory potential in selecting juvenile diabetics at risk of developing proliferative retinopathy | Q71079288 | ||
| Vitreal insulin-like growth factor binding proteins (IGFBPs) are increased in human and animal diabetics | Q71649607 | ||
| The relationship of glycemic exposure (HbA1c) to the risk of development and progression of retinopathy in the diabetes control and complications trial | Q71919192 | ||
| Progression of retinopathy with intensive versus conventional treatment in the Diabetes Control and Complications Trial. Diabetes Control and Complications Trial Research Group | Q72174601 | ||
| Multiple extracellular signals are required for long-term oligodendrocyte survival | Q72930271 | ||
| VEGF release by retinal glia depends on both oxygen and glucose supply | Q73234553 | ||
| Protective role of pigment epithelium-derived factor (PEDF) in early phase of experimental diabetic retinopathy | Q43290941 | ||
| Streptozotocin-induced diabetes causes metabolic changes and alterations in neurotrophin content and retrograde transport in the cervical vagus nerve | Q43649927 | ||
| Vascular endothelial growth factor-B and retinal vascular development in the mouse | Q44311473 | ||
| Pigment epithelium-derived factor prevents advanced glycation end products-induced monocyte chemoattractant protein-1 production in microvascular endothelial cells by suppressing intracellular reactive oxygen species generation | Q44355887 | ||
| Immunocytochemical localization of vascular endothelial growth factor in neurons and glial cells of human retina | Q44390940 | ||
| Insulin-like growth factor-I and its receptor in neovascular age-related macular degeneration. | Q44417319 | ||
| Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival | Q44659145 | ||
| Neuro-optic cell apoptosis and microangiopathy in KKAY mouse retina | Q44679483 | ||
| Pigment epithelium-derived factor inhibits TNF-alpha-induced interleukin-6 expression in endothelial cells by suppressing NADPH oxidase-mediated reactive oxygen species generation. | Q44994254 | ||
| PEDF derived from glial Müller cells: a possible regulator of retinal angiogenesis | Q45012429 | ||
| Death of retinal neurons in streptozotocin-induced diabetic mice | Q45028039 | ||
| Involvement of brain-derived neurotrophic factor in early retinal neuropathy of streptozotocin-induced diabetes in rats: therapeutic potential of brain-derived neurotrophic factor for dopaminergic amacrine cells | Q45032397 | ||
| Pegaptanib for neovascular age-related macular degeneration | Q45206481 | ||
| Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture | Q46084557 | ||
| Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy | Q46458778 | ||
| Transcorneal electrical stimulation rescues axotomized retinal ganglion cells by activating endogenous retinal IGF-1 system | Q46508379 | ||
| Diabetic retinopathy is associated with a switch in splicing from anti- to pro-angiogenic isoforms of vascular endothelial growth factor. | Q46727452 | ||
| Peroxynitrite mediates retinal neurodegeneration by inhibiting nerve growth factor survival signaling in experimental and human diabetes | Q46745027 | ||
| Serum and tear levels of nerve growth factor in diabetic retinopathy patients | Q46747209 | ||
| Expression of transforming growth factor-beta s and their receptors by human retinal glial cells | Q48002500 | ||
| Minocycline alleviates death of oligodendrocytes by inhibiting pro-nerve growth factor production in microglia after spinal cord injury. | Q48103125 | ||
| Pigment epithelium-derived factor protects cultured retinal neurons against hydrogen peroxide-induced cell death | Q48124300 | ||
| Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells | Q48297238 | ||
| Neurotrophins in the developing and regenerating visual system | Q48468517 | ||
| Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75. | Q48887712 | ||
| Cannabidiol protects retinal neurons by preserving glutamine synthetase activity in diabetes | Q34079326 | ||
| Expression, regulation, and function of IGF-1, IGF-1R, and IGF-1 binding proteins in blood vessels | Q34275284 | ||
| Altered plasma levels of nerve growth factor and transforming growth factor-beta2 in type-1 diabetes mellitus | Q34506251 | ||
| Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade | Q34598030 | ||
| Ranibizumab versus verteporfin for neovascular age-related macular degeneration. | Q34652928 | ||
| Ranibizumab combined with verteporfin photodynamic therapy in neovascular age-related macular degeneration: year 1 results of the FOCUS Study. | Q34653066 | ||
| The many faces of p75NTR. | Q34671388 | ||
| Molecular understanding of hyperglycemia's adverse effects for diabetic complications | Q35005662 | ||
| Neuroprotective and blood-retinal barrier-preserving effects of cannabidiol in experimental diabetes | Q35070770 | ||
| A new view of diabetic retinopathy: a neurodegenerative disease of the eye. | Q35092253 | ||
| Construction of a mutated pro-nerve growth factor resistant to degradation and suitable for biophysical and cellular utilization | Q35215109 | ||
| Intravitreal growth factors in proliferative diabetic retinopathy: correlation with neovascular activity and glycaemic management | Q35299525 | ||
| Neuroprotective and antiangiogenic actions of PEDF in the eye: molecular targets and therapeutic potential. | Q35859456 | ||
| Neural regeneration in the chick retina | Q35989973 | ||
| Neuroprotective role of vascular endothelial growth factor: signalling mechanisms, biological function, and therapeutic potential | Q36319049 | ||
| Focus on Molecules: Pigment epithelium-derived factor (PEDF). | Q36346539 | ||
| Nerve growth factor prevents both neuroretinal programmed cell death and capillary pathology in experimental diabetes | Q36437521 | ||
| Müller cells in the healthy and diseased retina | Q36535340 | ||
| The quest for remyelination: a new role for neurotrophins and their receptors | Q36654488 | ||
| The role of growth hormone, insulin-like growth factor and somatostatin in diabetic retinopathy. | Q36683919 | ||
| Neurotrophins and their receptors: roles in plasticity, neurodegeneration and neuroprotection. | Q36764130 | ||
| Intravitreous anti-VEGF for diabetic retinopathy: hopes and fears for a new therapeutic strategy | Q37135388 | ||
| The Wisconsin Epidemiologic Study of Diabetic Retinopathy XXIII: the twenty-five-year incidence of macular edema in persons with type 1 diabetes | Q37218851 | ||
| Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin | Q37384532 | ||
| Brain angiogenesis in developmental and pathological processes: therapeutic aspects of vascular endothelial growth factor | Q37576019 | ||
| A review of clinical trials of anti-VEGF agents for diabetic retinopathy | Q37696351 | ||
| Epicatechin blocks pro-nerve growth factor (proNGF)-mediated retinal neurodegeneration via inhibition of p75 neurotrophin receptor expression in a rat model of diabetes [corrected]. | Q39623177 | ||
| Diabetes-induced peroxynitrite impairs the balance of pro-nerve growth factor and nerve growth factor, and causes neurovascular injury | Q39642476 | ||
| Commentary: Regulating proNGF action: multiple targets for therapeutic intervention | Q39971070 | ||
| The molecular basis of oxidative stress-induced cell death in an immortalized retinal ganglion cell line. | Q40465472 | ||
| Microglia-Müller glia cell interactions control neurotrophic factor production during light-induced retinal degeneration. | Q40692091 | ||
| Excessive hexosamines block the neuroprotective effect of insulin and induce apoptosis in retinal neurons | Q40780090 | ||
| Insulin rescues retinal neurons from apoptosis by a phosphatidylinositol 3-kinase/Akt-mediated mechanism that reduces the activation of caspase-3. | Q40793937 | ||
| Insulin attenuates ischemic brain damage independent of its hypoglycemic effect. | Q41169952 | ||
| Subconjunctivally implantable hydrogels with degradable and thermoresponsive properties for sustained release of insulin to the retina. | Q42270577 | ||
| Oxidative stress inactivates VEGF survival signaling in retinal endothelial cells via PI 3-kinase tyrosine nitration | Q42472180 | ||
| Diabetes reduces basal retinal insulin receptor signaling: reversal with systemic and local insulin | Q42492673 | ||
| Effect of memantine on neuroretinal function and retinal vascular changes of streptozotocin-induced diabetic rats | Q42520811 | ||
| In vivo protection of photoreceptors from light damage by pigment epithelium-derived factor | Q42651056 | ||
| P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P921 | main subject | nervous system | Q9404 |
| cell | Q7868 | ||
| peptide | Q172847 | ||
| diabetic retinopathy | Q631361 | ||
| P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
| P304 | page(s) | 300-308 | |
| P577 | publication date | 2011-01-28 | |
| P1433 | published in | Molecular Vision | Q6895981 |
| P1476 | title | Alteration of growth factors and neuronal death in diabetic retinopathy: what we have learned so far | |
| P478 | volume | 17 |
| Q35550002 | A comparative study on the transplantation of different concentrations of human umbilical mesenchymal cells into diabetic rats |
| Q36408728 | Adult mice transplanted with embryonic retinal progenitor cells: new approach for repairing damaged optic nerves. |
| Q93047812 | Biological characteristics of dynamic expression of nerve regeneration related growth factors in dorsal root ganglia after peripheral nerve injury |
| Q37179640 | CNTF Attenuates Vasoproliferative Changes Through Upregulation of SOCS3 in a Mouse-Model of Oxygen-Induced Retinopathy |
| Q38185249 | Cerebral neovascularization in diabetes: implications for stroke recovery and beyond |
| Q34564352 | Choosing preclinical study models of diabetic retinopathy: key problems for consideration |
| Q88368624 | Deletion of the Neurotrophin Receptor p75NTR Prevents Diabetes-Induced Retinal Acellular Capillaries in Streptozotocin-Induced Mouse Diabetic Model |
| Q37635278 | Deletion of thioredoxin-interacting protein preserves retinal neuronal function by preventing inflammation and vascular injury |
| Q41021679 | Diabetes causes transient changes in the composition and phosphorylation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors and interaction with auxiliary proteins in the rat retina |
| Q35591952 | Diabetic bladder dysfunction |
| Q92339144 | Effect of Insulin-Like Growth Factor-1 on Diabetic Retinopathy in Pubertal Age Patients With Type 1 Diabetes |
| Q33833070 | Effects of miRNA-200b on the development of diabetic retinopathy by targeting VEGFA gene |
| Q47987289 | Enhanced VEGF signalling mediates cerebral neovascularisation via downregulation of guidance protein ROBO4 in a rat model of diabetes |
| Q35976637 | Enhanced cerebral but not peripheral angiogenesis in the Goto-Kakizaki model of type 2 diabetes involves VEGF and peroxynitrite signaling |
| Q38711905 | Implication of VEGF and aquaporin 4 mediating Müller cell swelling to diabetic retinal edema |
| Q34532646 | Ischemic conditioning protects from axoglial alterations of the optic pathway induced by experimental diabetes in rats |
| Q38071621 | Matters of life and death: the role of chromatin remodeling proteins in retinal neuron survival |
| Q26786398 | Nerve Growth Factor: A Focus on Neuroscience and Therapy |
| Q37965160 | Neural degeneration in the retina of the streptozotocin-induced type 1 diabetes model |
| Q52372755 | Neuroprotective strategies for retinal disease. |
| Q36077937 | Oxidative stress impact on growth hormone secretion in the eye |
| Q37122419 | Pronerve growth factor induces angiogenesis via activation of TrkA: possible role in proliferative diabetic retinopathy. |
| Q37677024 | Retinal Neurodegeneration in the Course of Diabetes-Pathogenesis and Clinical Perspective |
| Q38256054 | Role of inflammasome activation in the pathophysiology of vascular diseases of the neurovascular unit. |
| Q47133435 | Silymarin Ameliorates Diabetes-Induced Proangiogenic Response in Brain Endothelial Cells through a GSK-3β Inhibition-Induced Reduction of VEGF Release |
| Q36380233 | Subconjunctivally Implanted Hydrogels for Sustained Insulin Release to Reduce Retinal Cell Apoptosis in Diabetic Rats |
| Q36317120 | The putative role of lutein and zeaxanthin as protective agents against age-related macular degeneration: promise of molecular genetics for guiding mechanistic and translational research in the field. |
| Q38387172 | Thioredoxin interacting protein is a novel mediator of retinal inflammation and neurotoxicity. |
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