Amplification of human platelet activation by surface pannexin-1 channels

scientific article

Amplification of human platelet activation by surface pannexin-1 channels is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/JTH.12566
P932PMC publication ID4238786
P698PubMed publication ID24655807
P5875ResearchGate publication ID261032530

P50authorKirk A TaylorQ57078782
Joy R WrightQ83974662
P2093author name stringR J Evans
M P Mahaut-Smith
C Vial
P2860cites workPannexin 3 inhibits proliferation of osteoprogenitor cells by regulating Wnt and p21 signalingQ37536548
Pannexins, distant relatives of the connexin family with specific cellular functions?Q37567592
Pannexin 1 forms an anion-selective channelQ39400579
Organic anion transport in macrophage membrane vesiclesQ41744341
Pharmacological characterization of pannexin-1 currents expressed in mammalian cellsQ41871358
Platelet Ca(2+) responses coupled to glycoprotein VI and Toll-like receptors persist in the presence of endothelial-derived inhibitors: roles for secondary activation of P2X1 receptors and release from intracellular Ca(2+) storesQ42326717
Gating of cx46 gap junction hemichannels by calcium and voltageQ42690335
Protein kinase C alpha enhances sodium–calcium exchange during store-operated calcium entry in mouse plateletsQ42795655
Transient receptor potential channels function as a coincidence signal detector mediating phosphatidylserine exposure.Q45018629
Connexin 37 limits thrombus propensity by downregulating platelet reactivity.Q45990622
Protein kinase C-dependent and -independent mechanisms of dense granule exocytosis by human plateletsQ46633105
Activation of pannexin 1 channels by ATP through P2Y receptors and by cytoplasmic calciumQ46858670
Ischemia opens neuronal gap junction hemichannelsQ48543854
A rapid and efficient platelet purification protocol for platelet gene expression studiesQ50521529
Anion blockers inhibit impulse-evoked quantal transmitter release at the crayfish neuromuscular junctionQ72539546
Mechanism of organic anion transport across the apical membrane of choroid plexusQ73176051
Platelet shape change evoked by selective activation of P2X1 purinoceptors with alpha,beta-methylene ATPQ73607561
Presence of P2X1 purinoceptors in human platelets and megakaryoblastic cell linesQ74019347
Techniques for analysis of proteins by SDS-polyacrylamide gel electrophoresis and Western blottingQ80446116
A major role for P2X1 receptors in the early collagen-evoked intracellular Ca2+ responses of human plateletsQ81094088
Neurons respond directly to mechanical deformation with pannexin-mediated ATP release and autostimulation of P2X7 receptorsQ83629988
Pannexin1 channels contain a glycosylation site that targets the hexamer to the plasma membraneQ24338217
Probenecid, a gout remedy, inhibits pannexin 1 channelsQ24647558
A ubiquitous family of putative gap junction moleculesQ28140991
Primary and secondary agonists can use P2X(1) receptors as a major pathway to increase intracellular Ca(2+) in the human plateletQ28221012
Pannexins in ischemia-induced neurodegenerationQ28254782
Pannexin membrane channels are mechanosensitive conduits for ATPQ28276454
Depolarisation-evoked Ca2+ waves in the non-excitable rat megakaryocyteQ28365671
A role of the fast ATP-gated P2X1 cation channel in thrombosis of small arteries in vivoQ28513773
Pannexins, a family of gap junction proteins expressed in brainQ28567263
Pannexin 1, an ATP release channel, is activated by caspase cleavage of its pore-associated C-terminal autoinhibitory regionQ30421727
Synergism between platelet collagen receptors defined using receptor-specific collagen-mimetic peptide substrata in flowing bloodQ30495037
Heat shock protein 90 inhibitors reduce trafficking of ATP-gated P2X1 receptors and human platelet responsivenessQ30525479
Inhibition of platelet functions and thrombosis through selective or nonselective inhibition of the platelet P2 receptors with increasing doses of NF449 [4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis-(carbonylimino)))tetrakis-benzene-1,3-diQ30780555
Calcium-dependent open/closed conformations and interfacial energy maps of reconstituted hemichannelsQ33210292
Pannexin-1 hemichannel-mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapseQ34128014
Pannexin 1 is the conduit for low oxygen tension-induced ATP release from human erythrocytesQ34212229
Gap junctions and connexin hemichannels underpin hemostasis and thrombosis.Q34243239
P2X1-mediated ERK2 Activation Amplifies the Collagen-induced Platelet Secretion by Enhancing Myosin Light Chain Kinase ActivationQ34263918
Pannexin 1 in erythrocytes: function without a gapQ34650659
Molecular basis of calcium regulation in connexin-32 hemichannelsQ34794839
Atomic force microscopy of Connexin40 gap junction hemichannels reveals calcium-dependent three-dimensional molecular topography and open-closed conformations of both the extracellular and cytoplasmic faces.Q35063040
Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitisQ35874789
Cell-cell communication beyond connexins: the pannexin channelsQ36432219
Properties of a nonjunctional current expressed from a rat connexin46 cDNA in Xenopus oocytesQ36435171
Trafficking dynamics of glycosylated pannexin 1 proteinsQ36860965
Connexins, pannexins, innexins: novel roles of "hemi-channels"Q37130086
Connexin40 regulates platelet functionQ37250478
Glycosylation regulates pannexin intermixing and cellular localizationQ37388212
Calcium signaling in plateletsQ37473529
P433issue6
P304page(s)987-998
P577publication date2014-06-01
P1433published inJournal of Thrombosis and HaemostasisQ6296004
P1476titleAmplification of human platelet activation by surface pannexin-1 channels
P478volume12

Reverse relations

cites work (P2860)
Q90126770A major interspecies difference in the ionic selectivity of megakaryocyte Ca2+-activated channels sensitive to the TMEM16F inhibitor CaCCinh-A01
Q36954835A new perspective of mechanosensitive pannexin-1 channels in cancer metastasis: clues for the treatment of other stress-induced diseases
Q38830299Calcium Signalling through Ligand-Gated Ion Channels such as P2X1 Receptors in the Platelet and other Non-Excitable Cells.
Q56363256Connexins and Pannexins in Vascular Function and Disease
Q47770967Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications
Q38491295Extracellular ATP metabolism on vascular endothelial cells: A pathway with pro-thrombotic and anti-thrombotic molecules.
Q38670294Extracellular chloride is required for efficient platelet aggregation.
Q90751615Inhibition of pannexin-1 channel activity by adiponectin in podocytes: Role of acid ceramidase activation
Q55026641Mechanisms of ATP Release by Inflammatory Cells.
Q35832975Oncogenic extracellular HSP70 disrupts the gap-junctional coupling between capillary cells
Q41812761Pannexin 1 channels: new actors in the regulation of catecholamine release from adrenal chromaffin cells
Q30274918Pannexin channel and connexin hemichannel expression in vascular function and inflammation
Q39179457Pannexin hemichannels: A novel promising therapy target for oxidative stress related diseases
Q33624852Pannexin- and Connexin-Mediated Intercellular Communication in Platelet Function.
Q51159920Pannexin1 Single Nucleotide Polymorphism and Platelet Reactivity in a Cohort of Cardiovascular Patients.
Q38980718Pannexin1 as mediator of inflammation and cell death.
Q26765384Platelet signaling: a complex interplay between inhibitory and activatory networks
Q55404446Refinement of a mouse cardiovascular model: Development, application and dissemination.
Q38502114Regulation of Pannexin-1 channel activity.
Q50081249Routine clinical anti-platelet agents have limited efficacy in modulating hypershear-mediated platelet activation associated with mechanical circulatory support.
Q51092906Shear-mediated platelet activation in the free flow: Perspectives on the emerging spectrum of cell mechanobiological mechanisms mediating cardiovascular implant thrombosis.
Q90734293Thrombophilia Caused by Beta2-Glycoprotein I Deficiency: In Vitro Study of a Rare Mutation in APOH Gene
Q50215851Transcriptomic analysis of the ion channelome of human platelets and megakaryocytic cell lines.
Q50115928Translational Implications of Platelets as Vascular First Responders
Q50177876Turbidimetry on Human Washed Platelets: The Effect of the Pannexin1-inhibitor Brilliant Blue FCF on Collagen-induced Aggregation.

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