Recombinant bacteriophage lysins as antibacterials

scientific article

Recombinant bacteriophage lysins as antibacterials is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.4161/BBUG.1.1.9818
P8608Fatcat IDrelease_z5vgyewtjzhpfegzigiwz64x3i
P932PMC publication ID3035150
P698PubMed publication ID21327123
P5875ResearchGate publication ID49841746

P50authorJim O'MahonyQ102065421
Olivia McAuliffeQ57011125
Reynolds Paul RossQ62566537
P2093author name stringMark Fenton
Aidan Coffey
P2860cites workProkaryotes: the unseen majorityQ22066200
Identification of a broadly active phage lytic enzyme with lethal activity against antibiotic-resistant Enterococcus faecalis and Enterococcus faeciumQ24563225
Prevention and elimination of upper respiratory colonization of mice by group A streptococci by using a bacteriophage lytic enzymeQ24609957
Bacteriophage lysis: mechanism and regulationQ24634690
Bacteriophage lysins as effective antibacterialsQ24648457
Phage Lytic Enzyme Cpl-1 as a Novel Antimicrobial for Pneumococcal BacteremiaQ24671527
Crystal structures of a T4-lysozyme duplication-extension mutant demonstrate that the highly conserved beta-sheet region has low intrinsic folding propensityQ27638222
Structural basis for selective recognition of pneumococcal cell wall by modular endolysin from phage Cp-1Q27642277
The 1.6 A crystal structure of the catalytic domain of PlyB, a bacteriophage lysin active against Bacillus anthracisQ27643380
The structure of bacteriophage T7 lysozyme, a zinc amidase and an inhibitor of T7 RNA polymeraseQ27731300
Staphylococcus aureus infectionsQ28131787
Holins: the protein clocks of bacteriophage infectionsQ28140369
Multiple enzymatic activities of the murein hydrolase from staphylococcal phage phi11. Identification of a D-alanyl-glycine endopeptidase activityQ28144392
C-terminal domains of Listeria monocytogenes bacteriophage murein hydrolases determine specific recognition and high-affinity binding to bacterial cell wall carbohydratesQ28215660
Modular organization of the lytic enzymes of Streptococcus pneumoniae and its bacteriophagesQ28278525
AN INVESTIGATION ON THE NATURE OF ULTRA-MICROSCOPIC VIRUSES.Q29039000
Anthrax as a biological weapon, 2002: updated recommendations for managementQ29615587
The crystal structure of the bacteriophage PSA endolysin reveals a unique fold responsible for specific recognition of Listeria cell wallsQ30159623
The two-component cell lysis genes holWMY and lysWMY of the Staphylococcus warneri M phage varphiWMY: cloning, sequencing, expression, and mutational analysis in Escherichia coliQ30160261
Novel strategy to prevent otitis media caused by colonizing Streptococcus pneumoniaeQ33279810
Removal of group B streptococci colonizing the vagina and oropharynx of mice with a bacteriophage lytic enzymeQ33555987
A novel gene required for rhamnose-glucose polysaccharide synthesis in Streptococcus mutansQ33638582
Chimeric phage-bacterial enzymes: a clue to the modular evolution of genesQ33851733
Gene cloning and expression and secretion of Listeria monocytogenes bacteriophage-lytic enzymes in Lactococcus lactisQ33987196
The recombinant phage lysin LysK has a broad spectrum of lytic activity against clinically relevant staphylococci, including methicillin-resistant Staphylococcus aureusQ34077249
Phage lysin LysK can be truncated to its CHAP domain and retain lytic activity against live antibiotic-resistant staphylococci.Q43192489
Systemic use of the endolysin Cpl-1 rescues mice with fatal pneumococcal pneumonia.Q43511826
Food-grade controlled lysis of Lactococcus lactis for accelerated cheese ripeningQ43682283
Mechanism Of Phage-Induced Lysis In PneumococciQ43767971
Rapid killing of Streptococcus pneumoniae with a bacteriophage cell wall hydrolaseQ43820230
Virus deals anthrax a killer blowQ44111935
The bifunctional peptidoglycan lysin of Streptococcus agalactiae bacteriophage B30.Q44980874
Phage lytic enzymes as therapy for antibiotic-resistant Streptococcus pneumoniae infection in a murine sepsis model.Q45172053
Purified recombinant phage lysin LySMP: an extensive spectrum of lytic activity for swine streptococciQ46097663
Lytic activity of the recombinant staphylococcal bacteriophage PhiH5 endolysin active against Staphylococcus aureus in milkQ46353015
The phage K lytic enzyme LysK and lysostaphin act synergistically to kill MRSA.Q46415786
In vitro antimicrobial susceptibility of Streptococcus suis strains isolated from clinically healthy sows in ChinaQ46579198
Phage lytic enzyme Cpl-1 for antibacterial therapy in experimental pneumococcal meningitisQ46602101
Structure and lytic activity of a Bacillus anthracis prophage endolysinQ46639780
PlyC, a novel bacteriophage lysin for compartment-dependent proteomics of group A streptococciQ46839723
Efficient elimination of multidrug-resistant Staphylococcus aureus by cloned lysin derived from bacteriophage phi MR11.Q46936223
The high-affinity peptidoglycan binding domain of Pseudomonas phage endolysin KZ144.Q50597508
Mutational and biochemical analyses of the endolysin Lys(gaY) encoded by the Lactobacillus gasseri JCM 1131T phage phi gaY.Q50895420
Construction of a multifunctional pneumococcal murein hydrolase by module assemblyQ56903510
Role for bacteriophages in the preparedness for fighting against pneumonia in the postantibiotic eraQ57113028
Complications associated with Streptococcus equi infection on a horse farmQ69472219
Analysis of the catalytic domain of the lysin of the lactococcal bacteriophage Tuc2009 by chimeric gene assemblingQ71150328
Interchange of functional domains switches enzyme specificity: construction of a chimeric pneumococcal-clostridial cell wall lytic enzymeQ72738407
Community-acquired pneumoniaQ77464123
The non-enzymatic microbicidal activity of lysozymesQ77780831
Lysis of staphylococcal mastitis pathogens by bacteriophage phi11 endolysinQ79281958
Mutagenesis of a bacteriophage lytic enzyme PlyGBS significantly increases its antibacterial activity against group B streptococciQ79448668
Functional analysis of the lysis genes of Staphylococcus aureus phage P68 in Escherichia coliQ80341250
Bi-functional activities of chimeric lysozymes constructed by domain swapping between bacteriophage T7 and K11 lysozymesQ80721130
In vitro interactions of LytA, the major pneumococcal autolysin, with two bacteriophage lytic enzymes (Cpl-1 and Pal), cefotaxime and moxifloxacin against antibiotic-susceptible and -resistant Streptococcus pneumoniae strainsQ81162319
Therapeutic effects of bacteriophage Cpl-1 lysin against Streptococcus pneumoniae endocarditis in ratsQ34123647
A bacteriolytic agent that detects and kills Bacillus anthracisQ34145707
The murein hydrolase of the bacteriophage phi3626 dual lysis system is active against all tested Clostridium perfringens strainsQ34166006
Holins: form and function in bacteriophage lysisQ34304886
The crisis in antibiotic resistanceQ34314442
Bovine mastitis and intramammary drug delivery: review and perspectivesQ34334018
Filamentous phage assembly: variation on a protein export themeQ34432716
Bacteriophage therapy: a revitalized therapy against bacterial infectious diseasesQ34463971
The two-component lysis system of Staphylococcus aureus bacteriophage Twort: a large TTG-start holin and an associated amidase endolysinQ34471853
Isolation and expression of the lysis genes of Actinomyces naeslundii phage Av-1.Q34492001
Bacteriophage endolysins as a novel class of antibacterial agents.Q34505697
High abundance of viruses found in aquatic environments.Q34538292
Bacteriophages: an appraisal of their role in the treatment of bacterial infectionsQ34637115
Taking aim on bacterial pathogens: from phage therapy to enzybioticsQ34695345
PlyC: a multimeric bacteriophage lysinQ34708961
Viral infections and bovine mastitis: a reviewQ34740876
Novel Method to Control Pathogenic Bacteria on Human Mucous MembranesQ35119969
Staphylococcal resistance revisited: community-acquired methicillin resistant Staphylococcus aureus - an emerging problem for the management of skin and soft tissue infectionsQ35122747
How antibiotics can make us sick: the less obvious adverse effects of antimicrobial chemotherapyQ35903212
Recent trends on the molecular biology of pneumococcal capsules, lytic enzymes, and bacteriophageQ35946160
Bacteriophage endolysins--current state of research and applicationsQ36175326
Bacteriophage lytic enzymes: novel anti-infectivesQ36242302
LambdaSa1 and LambdaSa2 prophage lysins of Streptococcus agalactiaeQ36313687
Streptococcus suis: an emerging zoonotic pathogenQ36743342
Molecular characterization of a Clostridium difficile bacteriophage and its cloned biologically active endolysinQ36933726
Production and application of bacteriophage and bacteriophage-encoded lysinsQ37370715
Three Bacillus cereus bacteriophage endolysins are unrelated but reveal high homology to cell wall hydrolases from different bacilliQ38346480
Synergistic lethal effect of a combination of phage lytic enzymes with different activities on penicillin-sensitive and -resistant Streptococcus pneumoniae strainsQ39730777
Improved pharmacokinetics and reduced antibody reactivity of lysostaphin conjugated to polyethylene glycolQ39740458
A new procedure for efficient recovery of DNA, RNA, and proteins from Listeria cells by rapid lysis with a recombinant bacteriophage endolysinQ39797252
Characterization of a bacteriophage lysin (Ply700) from Streptococcus uberisQ40128035
Resistance to antimicrobial drugs--a worldwide calamityQ40880789
Synergistic killing of Streptococcus pneumoniae with the bacteriophage lytic enzyme Cpl-1 and penicillin or gentamicin depends on the level of penicillin resistanceQ41816188
PlyPH, a bacteriolytic enzyme with a broad pH range of activity and lytic action against Bacillus anthracisQ41892311
Use of a bacteriophage lysin, PlyC, as an enzyme disinfectant against Streptococcus equiQ42072836
Lytic activity of recombinant bacteriophage phi11 and phi12 endolysins on whole cells and biofilms of Staphylococcus aureus.Q42121862
Expression of bacteriophage phiEa1h lysozyme in Escherichia coli and its activity in growth inhibition of Erwinia amylovoraQ42632691
The Clostridium perfringens enterotoxin gene is on a transposable element in type A human food poisoning strainsQ42661388
Use of high-affinity cell wall-binding domains of bacteriophage endolysins for immobilization and separation of bacterial cellsQ42912879
P433issue1
P921main subjectbacteriophageQ165028
P304page(s)9-16
P577publication date2010-01-01
P1433published inBioengineered bugsQ27723000
P1476titleRecombinant bacteriophage lysins as antibacterials
P478volume1

Reverse relations

cites work (P2860)
Q49941593Alternatives to antibiotics in poultry feed: molecular perspectives.
Q38165668Antibacterial bioagents based on principles of bacteriophage biology: an overview
Q27027984Antibiotic alternatives: the substitution of antibiotics in animal husbandry?
Q92697590Antimicrobial activity of Mycobacteriophage D29 Lysin B during Mycobacterium ulcerans infection
Q26781115Antimicrobial bacteriophage-derived proteins and therapeutic applications
Q38071062Antimicrobial enzymes: an emerging strategy to fight microbes and microbial biofilms
Q49631079Applications for Bacteriophage Therapy during Pregnancy and the Perinatal Period.
Q26824203Bacteriophage adenine methyltransferase: a life cycle regulator? Modelled using Vibrio harveyi myovirus like
Q38020842Bacteriophage based probes for pathogen detection.
Q34303439Bacteriophage endolysins as novel antimicrobials
Q38044739Bacteriophage virion-associated peptidoglycan hydrolases: potential new enzybiotics.
Q43245858Bacteriophage-Derived Peptidase CHAP(K) Eliminates and Prevents Staphylococcal Biofilms
Q38537430Bacteriophages and bacteriophage-derived endolysins as potential therapeutics to combat Gram-positive spore forming bacteria
Q28082731Bacteriophages and phage-derived proteins--application approaches
Q35963673Bacteriophages and phage-inspired nanocarriers for targeted delivery of therapeutic cargos
Q37607761Bioengineered probiotics, a strategic approach to control enteric infections
Q64087615Cell Wall Hydrolases in Bacteria: Insight on the Diversity of Cell Wall Amidases, Glycosidases and Peptidases Toward Peptidoglycan
Q47192883Characterisation of the antibacterial properties of the recombinant phage endolysins AP50-31 and LysB4 as potent bactericidal agents against Bacillus anthracis
Q21245089Characterization and determination of holin protein of Streptococcus suis bacteriophage SMP in heterologous host
Q44488180Characterization of the staphylococcal bacteriophage lysin CHAP(K).
Q26744448Choline Binding Proteins from Streptococcus pneumoniae: A Dual Role as Enzybiotics and Targets for the Design of New Antimicrobials
Q37696606Combination therapy with lysin CF-301 and antibiotic is superior to antibiotic alone for treating methicillin-resistant Staphylococcus aureus-induced murine bacteremia
Q45253895Comparative analysis of prophages in Streptococcus mutans genomes
Q40899441Comparison between a chimeric lysin ClyH and other enzymes for extracting DNA to detect methicillin resistant Staphylococcus aureus by quantitative PCR.
Q59359640Development of Phage Lysins as Novel Therapeutics: A Historical Perspective
Q40948487Dynamics of Mycobacteriophage-Mycobacterial Host Interaction: Evidence for Secondary Mechanisms for Host Lethality
Q41457130EC300: a phage-based, bacteriolysin-like protein with enhanced antibacterial activity against Enterococcus faecalis
Q34349552Engineered bacteriophage lysins as novel anti-infectives
Q42583742Enhanced staphylolytic activity of the Staphylococcus aureus bacteriophage vB_SauS-phiIPLA88 HydH5 virion-associated peptidoglycan hydrolase: fusions, deletions, and synergy with LysH5.
Q64936237Enzymatic Hydrolysis of Pneumococcal Capsular Polysaccharide Renders the Bacterium Vulnerable to Host Defense.
Q41601339Expression of Recombinant pET22b-LysK-Cysteine/Histidine-Dependent Amidohydrolase/Peptidase Bacteriophage Therapeutic Protein in Escherichia coli BL21 (DE3).
Q50016493Formation of biofilms under phage predation: considerations concerning a biofilm increase.
Q34435161Holins in bacteria, eukaryotes, and archaea: multifunctional xenologues with potential biotechnological and biomedical applications
Q64276230In Vitro Activity of the Bacteriophage Endolysin HY-133 against Small-Colony Variants and Their Corresponding Wild Types
Q42055505In silico modeling of the staphylococcal bacteriophage-derived peptidase CHAP(K).
Q94452171In vitro and in vivo efficacy of combinations of colistin and different endolysins against clinical strains of multi-drug resistant pathogens
Q36676044Learning from bacteriophages - advantages and limitations of phage and phage-encoded protein applications
Q90523185LysPBC2, a Novel Endolysin Harboring a Bacillus cereus Spore Binding Domain
Q64271021May the Phage be With You? Prophage-Like Elements in the Genomes of Soft Rot : spp. and spp
Q38644054Microbial approaches for targeting antibiotic-resistant bacteria
Q39531958Models for the directed evolution of bacterial allelopathy: bacteriophage lysins
Q21134546Molecular characterization of podoviral bacteriophages virulent for Clostridium perfringens and their comparison with members of the Picovirinae
Q38219163New perspectives on dietary-derived treatments and food safety-antinomy in a new era.
Q41918953Next generation sequencing technologies and the changing landscape of phage genomics
Q24609778Novel highly thermostable endolysin from Thermus scotoductus MAT2119 bacteriophage Ph2119 with amino acid sequence similarity to eukaryotic peptidoglycan recognition proteins
Q38053102Peptidoglycan hydrolases-potential weapons against Staphylococcus aureus
Q33726692Pharmacokinetics and Tolerance of the Phage Endolysin-Based Candidate Drug SAL200 after a Single Intravenous Administration among Healthy Volunteers.
Q33622902Preclinical safety evaluation of intravenously administered SAL200 containing the recombinant phage endolysin SAL-1 as a pharmaceutical ingredient
Q36031358Prediction of peptidoglycan hydrolases- a new class of antibacterial proteins
Q37977367Rapid detection methods for Bacillus anthracis in environmental samples: a review
Q38363778Reduced Binding of the Endolysin LysTP712 to Lactococcus lactis ΔftsH Contributes to Phage Resistance.
Q91790583Rumen Virus Populations: Technological Advances Enhancing Current Understanding
Q51878166Staphylococcus bacteriophage tails with bactericidal properties: new findings.
Q42223992The novel Shewanella putrefaciens-infecting bacteriophage Spp001: genome sequence and lytic enzymes
Q53686608The novel phage-derived antimicrobial agent HY-133 is active against livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA).
Q21089782The phage lytic proteins from the Staphylococcus aureus bacteriophage vB_SauS-phiIPLA88 display multiple active catalytic domains and do not trigger staphylococcal resistance
Q34664096The truncated phage lysin CHAP(k) eliminates Staphylococcus aureus in the nares of mice
Q34441804Thermal stability of Cpl-7 endolysin from the streptococcus pneumoniae bacteriophage Cp-7; cell wall-targeting of its CW_7 motifs
Q38051893Tools from viruses: bacteriophage successes and beyond
Q21133592Use of a bacteriophage lysin to identify a novel target for antimicrobial development
Q92235384Validation and Stabilization of a Prophage Lysin of Clostridium perfringens by Using Yeast Surface Display and Coevolutionary Models

Search more.