Review of the carcinogenic activity of diethanolamine and evidence of choline deficiency as a plausible mode of action

scientific article

Review of the carcinogenic activity of diethanolamine and evidence of choline deficiency as a plausible mode of action is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.YRTPH.2005.08.001
P698PubMed publication ID16188361

P2093author name stringLisa M Kamendulis
William T Stott
Hon-Wing Leung
P2860cites workResponses of transgenic mouse lines p53(+/-) and Tg.AC to agents tested in conventional carcinogenicity bioassaysQ28371963
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LIPIDS OF SUBCELLULAR PARTICLES.Q35523216
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Relationship of ethanol to choline metabolism in the liver: a reviewQ39900423
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Cancer risk in asphalt workers and roofers: review and meta-analysis of epidemiologic studiesQ40613757
Effect of choline deficiency on S-adenosylmethionine and methionine concentrations in rat liverQ41311794
Early stages of nodular transformation of the B6C3F1 mouse liver induced by choline deficiencyQ41395111
The effect of diethanolamine on hepatic and renal phospholipid metabolism in the ratQ41592830
Diethanolamine-induced alteration of hepatic mitochondrial function and structureQ41592837
Initiation of hepatocarcinogenesis by endogenously formed N-nitrosobis(2-hydroxypropyl)amine, N-nitrosodiethanolamine and N-nitroso-2,6-dimethylmorpholine in ratsQ42479397
The pharmacokinetics of diethanolamine in Sprague-Dawley rats following intravenous administrationQ43702867
Diethanolamine induces hepatic choline deficiency in miceQ43964817
Investigations on cell proliferation in B6C3F(1) mouse liver by diethanolamineQ44663558
Genetic toxicology testing of 41 industrial chemicalsQ44942275
1,2-sn-diacylglycerol accumulates in choline-deficient liver. A possible mechanism of hepatic carcinogenesis via alteration in protein kinase C activity?Q45049625
Species differences in the induction of hepatocellular DNA synthesis by diethanolamineQ46598698
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Choline and human nutrition.Q48221812
Potential mechanisms of tumorigenic action of diethanolamine in miceQ50138612
Biological and environmental monitoring of occupational exposure to cyclophosphamide in industry and hospitalsQ50198295
Toxicity of diethanolamine. 2. Drinking water and topical application exposures in B6C3F1 mice.Q52514688
Cell proliferation and global methylation status changes in mouse liver after phenobarbital and/or choline-devoid, methionine-deficient diet administration.Q53454086
Mouse Liver Carcinogenesis: Mechanisms and Relevance*1Q53495721
Metabolism, bioaccumulation, and incorporation of diethanolamine into phospholipids.Q53898117
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Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro: II. Results with 20 chemicalsQ69481947
DNA methylation and hepatocarcinogenesis in rats fed a choline-devoid dietQ69566674
Toxicity of diethanolamine in miceQ70426763
Rapid lipid peroxidation in the nuclear fraction of rat liver induced by a diet deficient in choline and methionineQ70669348
Urinary excretion of N-nitrosodiethanolamine in rats following its epicutaneous and intratracheal administration and its formation in vivo following skin application of diethanolamineQ70970053
Amphibian micronucleus test(s): a simple and reliable method for evaluating in vivo genotoxic effects of freshwater pollutants and radiations. Initial assessmentQ72089411
Betaine aldehyde, betaine, and choline levels in rat livers during ethanol metabolismQ73186745
Diethanolamine absorption, metabolism and disposition in rat and mouse following oral, intravenous and dermal administrationQ73577608
Choline supplementation inhibits diethanolamine-induced morphological transformation in syrian hamster embryo cells: evidence for a carcinogenic mechanismQ73827788
Diethanolamine inhibits choline uptake and phosphatidylcholine synthesis in Chinese hamster ovary cellsQ78202627
Liver choline oxidase activity in man and in several species of animalsQ78919742
Effects of choline deficiency and methotrexate treatment upon rat liverQ80991181
A study of the hemorrhagic-kidney syndrome of choline deficiency: the protective effect of starchQ83253354
Proliferative liver lesions and sex steroids in ratsQ89948487
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)260-271
P577publication date2005-09-26
P1433published inRegulatory Toxicology and PharmacologyQ2138805
P1476titleReview of the carcinogenic activity of diethanolamine and evidence of choline deficiency as a plausible mode of action
P478volume43

Reverse relations

cites work (P2860)
Q43688048Derivation of a No-Significant-Risk-Level (NSRL) for diethanolamine (DEA).
Q40019046Derivation of a No-significant-risk-level (NSRL) for dermal exposures to diethanolamine
Q35046561Diethanolamine alters neurogenesis and induces apoptosis in fetal mouse hippocampus
Q24655718Dose response effects of dermally applied diethanolamine on neurogenesis in fetal mouse hippocampus and potential exposure of humans
Q38133745Potential occupational risk of amines in carbon capture for power generation
Q47809568Safety Assessment of Diethanolamine and Its Salts as Used in Cosmetics

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