Central role of carotid body chemoreceptors in disordered breathing and cardiorenal dysfunction in chronic heart failure.

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Central role of carotid body chemoreceptors in disordered breathing and cardiorenal dysfunction in chronic heart failure. is …
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scholarly articleQ13442814

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P356DOI10.3389/FPHYS.2014.00438
P8608Fatcat IDrelease_ljhzlmraanballthntz6zohize
P932PMC publication ID4241833
P698PubMed publication ID25505417
P5875ResearchGate publication ID268802237

P50authorNoah J MarcusQ61196557
P2093author name stringHarold D Schultz
Rodrigo Del Rio
P2860cites workCentral respiratory modulation of medullary sympathoexcitatory neurons in rat.Q30461326
Chronic intermittent hypoxia augments chemoreflex control of sympathetic activity: role of the angiotensin II type 1 receptor.Q30475820
Improvement of sleep apnea in patients with chronic renal failure who undergo nocturnal hemodialysisQ31813752
Chemoreceptor hypersensitivity, sympathetic excitation, and overexpression of ASIC and TASK channels before the onset of hypertension in SHR.Q33755654
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Carotid body denervation improves autonomic and cardiac function and attenuates disordered breathing in congestive heart failure.Q54576764
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Role of hyperventilation in the pathogenesis of central sleep apneas in patients with congestive heart failureQ72860707
Clinical characteristics of chronic heart failure patients with an augmented peripheral chemoreflexQ73168137
Oscillatory breathing patterns during wakefulness in patients with chronic heart failure: clinical implications and role of augmented peripheral chemosensitivityQ73267702
Abnormal awake respiratory patterns are common in chronic heart failure and may prevent evaluation of autonomic tone by measures of heart rate variabilityQ73542984
Effect of Cheyne-Stokes respiration on muscle sympathetic nerve activity in severe congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathyQ74251462
PERIODIC BREATHING OF PREMATURE INFANTSQ76890792
Enhanced peripheral chemoreflex function in conscious rabbits with pacing-induced heart failureQ77293225
Enhanced activity of carotid body chemoreceptors in rabbits with heart failure: role of nitric oxideQ77293229
The development of hyperventilation in patients with chronic heart failure and Cheyne-Strokes respiration: a possible role of chronic hypoxiaQ77477709
Enhanced sympathetic and ventilatory responses to central chemoreflex activation in heart failureQ78017138
Tonic chemoreflex activation contributes to the elevated muscle sympathetic nerve activity in patients with chronic renal failureQ79401441
Discharges in mammalian sympathetic nervesQ80327645
Angiotensin II enhances carotid body chemoreflex control of sympathetic outflow in chronic heart failure rabbitsQ83227640
Effect of acetazolamide on chemosensitivity, Cheyne-Stokes respiration, and response to effort in patients with heart failureQ83654834
Excessive sympathetic activation in heart failure with chronic renal failure: role of chemoreflex activationQ84097693
Prognostic value of nocturnal Cheyne-Stokes respiration in chronic heart failure.Q33855764
Chronic intermittent hypoxia affects integration of sensory input by neurons in the nucleus tractus solitariiQ34192196
The role of central chemosensitivity in central apnea of heart failureQ34340798
Renal denervation modulates angiotensin receptor expression in the renal cortex of rabbits with chronic heart failure.Q34501842
Daytime Cheyne-Stokes respiration in ambulatory patients with severe congestive heart failure is associated with increased mortality.Q34655252
Chemosensitivity in chronic heart failure.Q35084682
Effect of continuous positive airway pressure on ventricular ectopy in heart failure patients with obstructive sleep apnoea.Q35537962
Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: implications for recurrent apneasQ35812078
Cheyne-Stokes respiration in patients with congestive heart failure: causes and consequences.Q36247135
Respiratory modulation of the autonomic nervous system during Cheyne-Stokes respirationQ36538358
Contribution of peripheral chemoreceptors to ventilation and the effects of their suppression on exercise tolerance in chronic heart failureQ36838534
Inhibition of hydrogen sulfide restores normal breathing stability and improves autonomic control during experimental heart failure.Q36850784
Carotid chemoreceptor ablation improves survival in heart failure: rescuing autonomic control of cardiorespiratory function.Q37407921
Simvastatin treatment attenuates increased respiratory variability and apnea/hypopnea index in rats with chronic heart failureQ37712597
Cardiorenal syndrome: new perspectivesQ37765094
Does enhanced respiratory-sympathetic coupling contribute to peripheral neural mechanisms of angiotensin II-salt hypertension?Q39891994
Periodic breathing in heart failure patients: testing the hypothesis of instability of the chemoreflex loopQ40737561
Dependence of high altitude sleep apnea on ventilatory sensitivity to hypoxiaQ41570673
Effect of treatment with nasal continuous positive airway pressure on ventilatory response to hypoxia and hypercapnia in patients with sleep apnea syndromeQ42501175
Increased vasopressin transmission from the paraventricular nucleus to the rostral medulla augments cardiorespiratory outflow in chronic intermittent hypoxia-conditioned ratsQ43201829
Carotid body and cardiorespiratory alterations in intermittent hypoxia: the oxidative linkQ43227325
Peripheral chemoreceptor hypersensitivity: an ominous sign in patients with chronic heart failureQ44578930
Adaptive servo-ventilation in cardiac function and neurohormonal status in patients with heart failure and central sleep apnea nonresponsive to continuous positive airway pressureQ45384631
Adaptive servoventilation improves cardiorenal function and prognosis in heart failure patients with chronic kidney disease and sleep-disordered breathingQ45720586
Increased sympathetic outflow in juvenile rats submitted to chronic intermittent hypoxia correlates with enhanced expiratory activity.Q46010909
Gene transfer of neuronal nitric oxide synthase to carotid body reverses enhanced chemoreceptor function in heart failure rabbitsQ46580788
Altered sympathetic reflexes and vascular reactivity in rats after exposure to chronic intermittent hypoxiaQ46844633
Clinical significance of chemosensitivity in chronic heart failure: influence on neurohormonal derangement, Cheyne-Stokes respiration and arrhythmias.Q46931538
Increased peripheral chemoreceptors sensitivity and exercise ventilation in heart transplant recipientsQ47658137
Increased peripheral chemoreceptor activity may be critical in destabilizing breathing in neonatesQ47889318
Relationship of the ventilatory response to hypoxia with neonatal apnea in preterm infantsQ48010668
Hypertension is critically dependent on the carotid body input in the spontaneously hypertensive rat.Q48155344
Carotid body removal for treatment of chronic systolic heart failureQ48186408
Adaptive servo-ventilation improves renal function in patients with heart failureQ48281070
Effectiveness of adaptive servo-ventilation for treating heart failure regardless of the severity of sleep-disordered breathingQ48313574
Decreased chemosensitivity and improvement of sleep apnea by nocturnal hemodialysisQ48445161
Quality of life in patients with congestive heart failure and central sleep apneaQ48446061
A mechanism of central sleep apnea in patients with heart failureQ48743209
Chronic intermittent hypoxia alters glutamatergic control of sympathetic and respiratory activities in the commissural NTS of ratsQ48743580
Effects of inhaled carbon dioxide and oxygen on cheyne-stokes respiration in patients with heart failureQ48764933
Effects of nasal CPAP on sympathetic activity in patients with heart failure and central sleep apneaQ48809412
Carotid chemoreceptors, systemic blood pressure, and chronic episodic hypoxia mimicking sleep apneaQ48886308
Adaptive servo ventilation improves cardiac dysfunction and prognosis in chronic heart failure patients with Cheyne-Stokes respirationQ48956534
Tonic arterial chemoreceptor activity contributes to cardiac sympathetic activation in mild ovine heart failure.Q50637940
P921main subjectbreathingQ9530
heart failureQ181754
chemoreceptor cellQ1069641
chronic heart failureQ11829287
P304page(s)438
P577publication date2014-11-24
P1433published inFrontiers in PhysiologyQ2434141
P1476titleCentral role of carotid body chemoreceptors in disordered breathing and cardiorenal dysfunction in chronic heart failure
P478volume5

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cites work (P2860)
Q55075919Bidirectional Cardio-Respiratory Interactions in Heart Failure.
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Q28076487Carotid body chemoreceptors, sympathetic neural activation, and cardiometabolic disease
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Q38842860Contribution of peripheral and central chemoreceptors to sympatho-excitation in heart failure
Q41650255Editorial: Carotid body: a new target for rescuing neural control of cardiorespiratory balance in disease.
Q36480392Interindividual variability in the dose-specific effect of dopamine on carotid chemoreceptor sensitivity to hypoxia
Q26771307Relevance of the Carotid Body Chemoreflex in the Progression of Heart Failure
Q38572976Role of the Carotid Body Chemoreflex in the Pathophysiology of Heart Failure: A Perspective from Animal Studies.
Q39369116Sleep disturbance and sleep-disordered breathing in hemodialysis patients
Q47663408The hypoxic test in preterm neonates reinvestigated