Production of and in vitro response to interleukin 2 in the acquired immunodeficiency syndrome

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Production of and in vitro response to interleukin 2 in the acquired immunodeficiency syndrome is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI112194
P932PMC publication ID424252
P698PubMed publication ID2997299

P2093author name stringB Y Rubin
H W Murray
R B Roberts
K Welte
R Mertelsmann
J L Jacobs
P2860cites workPurification of human interleukin 2 to apparent homogeneity and its molecular heterogeneityQ24683640
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Interleukin-2 enhances the depressed natural killer and cytomegalovirus-specific cytotoxic activities of lymphocytes from patients with the acquired immune deficiency syndromeQ33821969
Decreased expression of human class II antigens on monocytes from patients with acquired immune deficiency syndrome. Increased expression with interferon-gammaQ34622269
Clearance rates and systemic effects of intravenously administered interleukin 2 (IL-2) containing preparations in human subjectsQ36047402
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Killing of intracellular Leishmania donovani by lymphokine-stimulated human mononuclear phagocytes. Evidence that interferon-gamma is the activating lymphokineQ36992102
Human lymphocytes with either the OKT4 or OKT8 phenotype produce interleukin 2 in cultureQ37016535
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Interferonlike factors from antigen- and mitogen-stimulated human leukocytes with antirickettsial and cytolytic actions on Rickettsia prowazekii. Infected human endothelial cells, fibroblasts, and macrophagesQ41854594
Response of resting human peripheral blood natural killer cells to interleukin 2.Q42153962
Activation of human macrophages. Comparison of other cytokines with interferon-gammaQ42232581
Cell-mediated immunity to cytomegalovirus (CMV) and herpes simplex virus (HSV) antigens in the acquired immune deficiency syndrome: interleukin-1 and interleukin-2 modify in vitro responsesQ45807835
Induction of crisis forms in the human malaria parasite Plasmodium falciparum by gamma-interferon-activated, monocyte-derived macrophagesQ47982109
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Defective in vitro T cell colony formation in the acquired immunodeficiency syndromeQ69863721
Interleukin 2 enhances the natural killer cell activity of acquired immunodeficiency syndrome patients through a gamma-interferon-independent mechanismQ69937749
The anticellular and protein-inducing activities of human gamma interferon preparations are mediated by the interferonQ70425115
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Purified human interleukin-2 enhances induction of immune interferonQ70440651
Impaired production of lymphokines and immune (gamma) interferon in the acquired immunodeficiency syndromeQ70468096
Interleukin 2 regulates expression of its receptor and synthesis of gamma interferon by human T lymphocytesQ70486953
Effect of murine interferon gamma on murine toxoplasmosisQ70507351
OKT8 antibody inhibits OKT3-induced IL 2 production and proliferation in OKT8+ cellsQ70995882
Defective T-cell response to PHA and mitogenic monoclonal antibodies in male homosexuals with acquired immunodeficiency syndrome and its in vitro correction by interleukin 2Q70999188
Cloned lines on interleukin 2 producer human T lymphocytesQ72117579
Human recombinant interleukin-2 partly reconstitutes deficient in-vitro immune responses of lymphocytes from patients with AIDSQ72575896
Interleukin 2 regulates immune interferon (IFN gamma) production by normal and suppressor cell culturesQ72659878
Interleukin 2 regulation of mitogen induction of immune interferon (IFN gamma) in spleen cells and thymocytesQ72662469
Capacity of human large granular lymphocytes (LGL) to produce multiple lymphokines: interleukin 2, interferon, and colony stimulating factorQ72715109
Augmentation of human natural cell-mediated cytotoxicity by recombinant human interleukin 2Q72736387
Effects of natural and recombinant IL 2 on regulation of IFN gamma production and natural killer activity: lack of involvement of the Tac antigen for these immunoregulatory effectsQ72736404
Cellular origin of interleukin 2 (IL 2) in man: evidence for stimulus-restricted IL 2 production by T4+ and T8+ T lymphocytesQ72762911
Immunologic effects of interleukin 2 in primary immunodeficiency diseasesQ72785416
Depressed interleukin 2 receptor expression in acquired immune deficiency and lymphadenopathy syndromesQ72820236
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)1959-1964
P577publication date1985-11-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleProduction of and in vitro response to interleukin 2 in the acquired immunodeficiency syndrome
P478volume76