Aberrant glycosylation and localization of polycystin-1 cause polycystic kidney in an AQP11 knockout model

scientific article

Aberrant glycosylation and localization of polycystin-1 cause polycystic kidney in an AQP11 knockout model is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1681/ASN.2013060614
P932PMC publication ID4243341
P698PubMed publication ID24854278
P5875ResearchGate publication ID262583429

P50authorShigeo HorieQ28691693
P2093author name stringJing Zhou
Kenichi Ishibashi
Sei Sasaki
Eisei Sohara
Yuichi Inoue
Xuefeng Su
Shinichi Uchida
Tatemitsu Rai
Motoko Chiga
Katsuki Kobayashi
P2860cites workCleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations.Q24336734
Simple and highly efficient BAC recombineering using galK selectionQ24794075
Water permeability and characterization of aquaporin-11.Q28000039
Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminusQ28506516
Disruption of aquaporin-11 produces polycystic kidneys following vacuolization of the proximal tubuleQ28507564
Aquaporin-11 containing a divergent NPA motif has normal water channel activityQ28509017
Cardiac defects and renal failure in mice with targeted mutations in Pkd2Q28510555
Single amino acid substitution in aquaporin 11 causes renal failureQ28513171
Nek8 regulates the expression and localization of polycystin-1 and polycystin-2Q28513278
A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formationQ28590393
Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagellaQ28593253
Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complexQ28594213
The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal ciliaQ29615732
Pkd1 transgenic mice: adult model of polycystic kidney disease with extrarenal and renal phenotypesQ30435066
Liver-specific Aquaporin 11 knockout mice show rapid vacuolization of the rough endoplasmic reticulum in periportal hepatocytes after amino acid feedingQ30583631
A loss-of-function model for cystogenesis in human autosomal dominant polycystic kidney disease type 2.Q33868896
Impaired urea accumulation in the inner medulla of mice lacking the urea transporter UT-A2.Q33924881
Acute insulin stimulation induces phosphorylation of the Na-Cl cotransporter in cultured distal mpkDCT cells and mouse kidneyQ34016466
Polycystin-1 surface localization is stimulated by polycystin-2 and cleavage at the G protein-coupled receptor proteolytic siteQ34408468
The NPC motif of aquaporin-11, unlike the NPA motif of known aquaporins, is essential for full expression of molecular function.Q34536847
Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney diseaseQ34982718
Pathogenesis and treatment of autosomal-dominant nephrogenic diabetes insipidus caused by an aquaporin 2 mutationQ35080543
Polycystin: in vitro synthesis, in vivo tissue expression, and subcellular localization identifies a large membrane-associated proteinQ36185189
Essential role of cleavage of Polycystin-1 at G protein-coupled receptor proteolytic site for kidney tubular structure.Q36276959
Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severityQ36357916
A polycystin-1 multiprotein complex is disrupted in polycystic kidney disease cellsQ36781051
Aquaporin 11 insufficiency modulates kidney susceptibility to oxidative stress.Q36836209
Polycystins and primary cilia: primers for cell cycle progressionQ37538766
Congenital disorders of glycosylation in hepatology: the example of polycystic liver diseaseQ37688598
Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney diseaseQ40332825
Phosphatidylinositol 3-kinase/Akt signaling pathway activates the WNK-OSR1/SPAK-NCC phosphorylation cascade in hyperinsulinemic db/db miceQ42135510
PKD1 haploinsufficiency causes a syndrome of inappropriate antidiuresis in miceQ42512106
Pancreas-specific aquaporin 12 null mice showed increased susceptibility to caerulein-induced acute pancreatitisQ43281809
Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutantQ44049169
In vivo protein biotinylation for identification of organ-specific antigens accessible from the vasculatureQ46396196
Polycystic kidneys caused by sustained expression of Cux1 isoform p75.Q46690342
Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cellsQ47785642
Development of polycystic kidney disease in juvenile cystic kidney mice: insights into pathogenesis, ciliary abnormalities, and common features with human disease.Q51789472
Defects in cholangiocyte fibrocystin expression and ciliary structure in the PCK rat.Q52552433
Aquaporin-11 knockout mice and polycystic kidney disease animals share a common mechanism of cyst formation.Q52587924
Somatic inactivation of Pkd2 results in polycystic kidney diseaseQ74502174
Somatic PKD2 mutations in individual kidney and liver cysts support a "two-hit" model of cystogenesis in type 2 autosomal dominant polycystic kidney diseaseQ77998428
P433issue12
P921main subjectglycosylationQ898365
Aquaporin 11Q21982760
P304page(s)2789-2799
P577publication date2014-05-22
P1433published inJournal of the American Society of NephrologyQ17123893
P1476titleAberrant glycosylation and localization of polycystin-1 cause polycystic kidney in an AQP11 knockout model
P478volume25

Reverse relations

cites work (P2860)
Q26800974A polycystin-centric view of cyst formation and disease: the polycystins revisited
Q37719527Abnormal glycosylation in Joubert syndrome type 10.
Q36828975Aquaporin 11, a regulator of water efflux at retinal Müller glial cell surface decreases concomitant with immune-mediated gliosis
Q42115780Aquaporin-11 (AQP11) Expression in the Mouse Brain
Q61815142Aquaporins in Renal Diseases
Q51112302Aquaporins in Urinary System.
Q52689816Deficient transient receptor potential vanilloid type 4 function contributes to compromised [Ca2+]i homeostasis in human autosomal-dominant polycystic kidney disease cells.
Q37534564Enhanced Autophagy in Polycystic Kidneys of AQP11 Null Mice
Q36061872Genetic predisposition of donors affects the allograft outcome in kidney transplantation: Single-nucleotide polymorphism of aquaporin-11
Q64103262Inhibitors of Mammalian Aquaporin Water Channels
Q60910381Involvement of the NADPH oxidase 2 pathway in renal oxidative stress in mice
Q51112320Molecular Biology of Aquaporins.
Q50211745Polycystic Kidney Disease with Hyperinsulinemic Hypoglycemia Caused by a Promoter Mutation in Phosphomannomutase 2.
Q47103366Proteomic analysis of AQP11-null kidney: Proximal tubular type polycystic kidney disease
Q49922693Renal involvement in PMM2-CDG, a mini-review.
Q48374920Temporal deletion of Aqp11 in mice is linked to the severity of cyst-like disease.
Q38707517The distribution and function of aquaporins in the kidney: resolved and unresolved questions

Search more.