| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1172/JCI0215293 |
| 10.1172/JCI15293 | ||
| P932 | PMC publication ID | 150919 |
| P698 | PubMed publication ID | 11901176 |
| P2093 | author name string | Francis X McCormack | |
| Jeffrey A Whitsett | |||
| P2860 | cites work | Altered surfactant homeostasis and alveolar type II cell morphology in mice lacking surfactant protein D | Q24317148 |
| Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice | Q24681813 | ||
| Trimeric structure of a C-type mannose-binding protein | Q27729941 | ||
| Surfactant protein A-deficient mice are susceptible to group B streptococcal infection | Q28236603 | ||
| Purification of a cell-surface receptor for surfactant protein A | Q28281937 | ||
| Surfactant protein-A-deficient mice are susceptible to Pseudomonas aeruginosa infection | Q28284528 | ||
| Pulmonary-specific expression of SP-D corrects pulmonary lipid accumulation in SP-D gene-targeted mice | Q28583311 | ||
| Surfactant Proteins A and D Bind CD14 by Different Mechanisms | Q29392656 | ||
| Salivary agglutinin, which binds Streptococcus mutans and Helicobacter pylori, is the lung scavenger receptor cysteine-rich protein gp-340. | Q30179427 | ||
| Surfactant protein-A enhances respiratory syncytial virus clearance in vivo | Q33848860 | ||
| Pulmonary surfactant and its components inhibit secretion of phosphatidylcholine from cultured rat alveolar type II cells | Q34596646 | ||
| Interactions of surfactant protein D with bacterial lipopolysaccharides. Surfactant protein D is an Escherichia coli-binding protein in bronchoalveolar lavage | Q35603494 | ||
| The human mannose-binding protein functions as an opsonin | Q36356275 | ||
| Altered surfactant function and structure in SP-A gene targeted mice | Q37357016 | ||
| Role of pulmonary surfactant protein D in innate defense against Candida albicans | Q38309209 | ||
| Binding of surfactant protein A (SP-A) to herpes simplex virus type 1-infected cells is mediated by the carbohydrate moiety of SP-A | Q38323659 | ||
| Epithelial cells as sensors for microbial infection | Q39786521 | ||
| Surfactant protein D regulates NF-kappa B and matrix metalloproteinase production in alveolar macrophages via oxidant-sensitive pathways | Q40801270 | ||
| Immunomodulatory functions of surfactant | Q40878977 | ||
| Collectins: pattern recognition molecules involved in first line host defense | Q40886106 | ||
| Surfactant protein A activates NF-kappa B in the THP-1 monocytic cell line | Q41096579 | ||
| Surfactant-associated protein inhibits phospholipid secretion from type II cells | Q42523875 | ||
| Binding of surfactant protein A to the lipid A moiety of bacterial lipopolysaccharides. | Q42829516 | ||
| Reconstitution of tubular myelin from synthetic lipids and proteins associated with pig pulmonary surfactant | Q44832470 | ||
| Surfactant protein D enhances clearance of influenza A virus from the lung in vivo | Q45734867 | ||
| Mannose-binding proteins isolated from rat liver contain carbohydrate-recognition domains linked to collagenous tails. Complete primary structures and homology with pulmonary surfactant apoprotein | Q48364924 | ||
| Serum lectin with known structure activates complement through the classical pathway. | Q53877303 | ||
| Normal surfactant pool sizes and inhibition-resistant surfactant from mice that overexpress surfactant protein A. | Q54081244 | ||
| Surfactant-associated protein A inhibits LPS-induced cytokine and nitric oxide production in vivo | Q56655892 | ||
| Properties, Function and Origin of the Alveolar Lining Layer | Q59070637 | ||
| Pulmonary surfactant-associated protein A enhances the surface activity of lipid extract surfactant and reverses inhibition by blood proteins in vitro | Q68622998 | ||
| Association of low levels of mannan-binding protein with a common defect of opsonisation | Q69376492 | ||
| Differential regulation of the mannose and SP-A receptors on macrophages | Q70926932 | ||
| Surfactant proteins A and D increase in response to intratracheal lipopolysaccharide | Q71701921 | ||
| Interaction of surfactant protein A with bacterial lipopolysaccharide may affect some biological functions | Q72492063 | ||
| Inhibition of lung calcium-independent phospholipase A2 by surfactant protein A | Q72761975 | ||
| Distinct effects of surfactant protein A or D deficiency during bacterial infection on the lung | Q73084779 | ||
| Surfactant protein A differentially regulates IFN-gamma- and LPS-induced nitrite production by rat alveolar macrophages | Q73265425 | ||
| Immunosuppressed surfactant protein A-deficient mice have increased susceptibility to Pneumocystis carinii infection | Q73585343 | ||
| The collagen-like region of surfactant protein A (SP-A) is required for correction of surfactant structural and functional defects in the SP-A null mouse | Q74371855 | ||
| Pulmonary surfactant protein A binds to Cryptococcus neoformans without promoting phagocytosis | Q74639012 | ||
| Surfactant protein-D regulates surfactant phospholipid homeostasis in vivo | Q77419163 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 707-712 | |
| P577 | publication date | 2002-03-01 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | The pulmonary collectins, SP-A and SP-D, orchestrate innate immunity in the lung | |
| P478 | volume | 109 |
| Q36376247 | Absence of the Macrophage Mannose Receptor in Mice Does Not Increase Susceptibility toPneumocystis cariniiInfection In Vivo |
| Q45016505 | Accumulation of inhibitory kappaB-alpha as a mechanism contributing to the anti-inflammatory effects of surfactant protein-A. |
| Q37576464 | Adenovirus-mediated gene therapy enhances parainfluenza virus 3 infection in neonatal lambs. |
| Q40582548 | Aggregation of Cryptococcus neoformans by surfactant protein D is inhibited by its capsular component glucuronoxylomannan |
| Q37208988 | Airway wall remodeling in asthma: from the epithelial layer to the adventitia |
| Q40410446 | Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cells |
| Q96128937 | Alveolar lipids in pulmonary disease. A review |
| Q35694784 | An official American Thoracic Society research statement: noninfectious lung injury after hematopoietic stem cell transplantation: idiopathic pneumonia syndrome |
| Q37598729 | Anti-Aspergillus fumigatus efficacy of pentraxin 3 alone and in combination with antifungals |
| Q36248322 | Antimicrobial peptides and surfactant proteins in ruminant respiratory tract disease |
| Q24541575 | Antimicrobial proteins and polypeptides in pulmonary innate defence |
| Q28077827 | Are healthy smokers really healthy? |
| Q33752029 | Assessment of Surfactant Protein A (SP-A) dependent agglutination |
| Q42145829 | Bacterial peptide recognition and immune activation facilitated by human peptide transporter PEPT2. |
| Q41849689 | Bordetella bronchiseptica adherence to cilia is mediated by multiple adhesin factors and blocked by surfactant protein A. |
| Q42397400 | Bordetella bronchiseptica responses to physiological reactive nitrogen and oxygen stresses |
| Q24657254 | Cap-independent translation of human SP-A 5'-UTR variants: a double-loop structure and cis-element contribution |
| Q33303634 | Cirrhosis-induced defects in innate pulmonary defenses against Streptococcus pneumoniae |
| Q38670558 | Co-infection of H9N2 subtype avian influenza virus and infectious bronchitis virus decreases SP-A expression level in chickens |
| Q36590997 | Collectins and cationic antimicrobial peptides of the respiratory epithelia. |
| Q24811611 | Comparative signature-tagged mutagenesis identifies Pseudomonas factors conferring resistance to the pulmonary collectin SP-A. |
| Q47763745 | Comparison of immunomodulator mRNA and protein expression in the lungs of Stachybotrys chartarum spore-exposed mice |
| Q33964051 | Critical role of airway macrophages in modulating disease severity during influenza virus infection of mice |
| Q27665573 | Crystallographic Complexes of Surfactant Protein A and Carbohydrates Reveal Ligand-induced Conformational Change |
| Q34568750 | Cytokines in innate host defense in the lung |
| Q28250832 | Differences in the translation efficiency and mRNA stability mediated by 5'-UTR splice variants of human SP-A1 and SP-A2 genes |
| Q42743844 | Dipeptidyl peptidase I controls survival from Klebsiella pneumoniae lung infection by processing surfactant protein D. |
| Q34459713 | Diseases of pulmonary surfactant homeostasis |
| Q41436455 | Disruption of the structural and functional features of surfactant protein A by acrolein in cigarette smoke |
| Q28571590 | Distribution of surfactant proteins in type II pneumocytes of newborn, 14-day old, and adult rats: an immunoelectron microscopic and stereological study |
| Q37285444 | Donor surfactant protein D (SP-D) polymorphisms are associated with lung transplant outcome |
| Q36072353 | Early expression of surfactant proteins D in Fusarium solani infected rat cornea |
| Q41850883 | Effect of edaravone on serum SP-A and arterial blood gas in patients with lobectomy. |
| Q27712375 | Elucidation of Lipid Binding Sites on Lung Surfactant Protein A Using X-ray Crystallography, Mutagenesis, and Molecular Dynamics Simulations |
| Q33711962 | Enhanced surfactant protein and defensin mRNA levels and reduced viral replication during parainfluenza virus type 3 pneumonia in neonatal lambs |
| Q33728231 | Functional importance of the NH2-terminal insertion sequence of lung surfactant protein B. |
| Q37691978 | Gastroesophageal reflux disease and graft failure after lung transplantation |
| Q37467891 | Gene profiling studies in the neonatal ovine lung show enhancing effects of VEGF on the immune response. |
| Q44951328 | General model of inflammation |
| Q46750635 | Genetic polymorphisms of surfactant protein D rs2243639, Interleukin (IL)-1β rs16944 and IL-1RN rs2234663 in chronic obstructive pulmonary disease, healthy smokers, and non-smokers |
| Q28256206 | Genetic variant associations of human SP-A and SP-D with acute and chronic lung injury |
| Q54336726 | Genetic variations of the bitter taste receptor TAS2R38 are associated with obesity and impact on single immune traits. |
| Q36238026 | Glucocorticoids enhance or spare innate immunity: effects in airway epithelium are mediated by CCAAT/enhancer binding proteins |
| Q33302233 | Granulocyte-macrophage colony stimulating factor-mediated innate responses in tuberculosis |
| Q37997098 | Health impact and toxicological effects of nanomaterials in the lung |
| Q27641758 | High-resolution structural insights into ligand binding and immune cell recognition by human lung surfactant protein D |
| Q28484199 | Human surfactant protein A2 gene mutations impair dimmer/trimer assembly leading to deficiency in protein sialylation and secretion |
| Q24677581 | Identification of the surfactant protein A receptor 210 as the unconventional myosin 18A. |
| Q58114739 | Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins |
| Q37195455 | Immune response to fungal infections |
| Q35131864 | Immunology of viral respiratory tract infection in infancy |
| Q36211208 | Implication of antigenic conversion of Helicobacter pylori lipopolysaccharides that involve interaction with surfactant protein D. |
| Q36262014 | Increased CD11b and Hypoxia-Inducible Factors-1alpha Expressions in the Lung Tissue and Surfactant Protein-D Levels in Serum Are Related with Acute Lung Injury in Severe Malaria of C57BL/6 Mice |
| Q36462744 | Innate immune responses to environmental allergens |
| Q30434628 | Innate immunity to Aspergillus species |
| Q37080749 | Interactions of nanoparticles with pulmonary structures and cellular responses |
| Q37623676 | Interactions of pulmonary collectins with Bordetella bronchiseptica and Bordetella pertussis lipopolysaccharide elucidate the structural basis of their antimicrobial activities |
| Q36902377 | Keratinocyte growth factor supports pulmonary innate immune defense through maintenance of alveolar antimicrobial protein levels and macrophage function |
| Q93211674 | Klebsiella pneumoniae infection biology: living to counteract host defences |
| Q33779595 | Lack of the pattern recognition molecule mannose-binding lectin increases susceptibility to influenza A virus infection |
| Q40630637 | Lactoferrin and surfactant protein A exhibit distinct binding specificity to F protein and differently modulate respiratory syncytial virus infection |
| Q38007176 | Lactoferrin: an alternative view of its role in human biological fluids |
| Q35573161 | Linkage of neutrophil serine proteases and decreased surfactant protein-A (SP-A) levels in inflammatory lung disease |
| Q46526078 | Lipid extraction mediates aggregation of carbon nanospheres in pulmonary surfactant monolayers |
| Q54363763 | Lipopolysaccharide-binding protein in microbial invasion of the amniotic cavity and human parturition. |
| Q28821832 | Low Levels of Exhaled Surfactant Protein A Associated With BOS After Lung Transplantation |
| Q40081742 | Lung epithelial cells modulate the inflammatory response of alveolar macrophages |
| Q36560016 | Lung surfactants |
| Q47903459 | Lysophospholipid generation and phosphatidylglycerol depletion in phospholipase A(2)-mediated surfactant dysfunction |
| Q33938380 | MCP-1 antibody treatment enhances damage and impedes repair of the alveolar epithelium in influenza pneumonitis |
| Q24646805 | Mechanisms and function of DUOX in epithelia of the lung |
| Q36345006 | Metal nanoparticle pollutants interfere with pulmonary surfactant function in vitro |
| Q51805596 | Microfibril-associated protein 4 binds to surfactant protein A (SP-A) and colocalizes with SP-A in the extracellular matrix of the lung. |
| Q40333962 | Mite allergen induces nitric oxide production in alveolar macrophage cell lines via CD14/toll-like receptor 4, and is inhibited by surfactant protein D. |
| Q41469884 | Morphological alterations of exogenous surfactant inhibited by meconium can be prevented by dextran |
| Q36657670 | Neonatal hyperoxia enhances the inflammatory response in adult mice infected with influenza A virus |
| Q33799579 | Neonatal hyperoxia stimulates the expansion of alveolar epithelial type II cells |
| Q28512650 | Neonatal oxygen increases sensitivity to influenza A virus infection in adult mice by suppressing epithelial expression of Ear1 |
| Q61959699 | Oxidative damage of SP-D abolishes control of eosinophil extracellular DNA trap formation |
| Q36426181 | Ozone-induced lung injury and sterile inflammation. Role of toll-like receptor 4. |
| Q36032639 | Pathogen-host interactions in Pseudomonas aeruginosa pneumonia |
| Q35779090 | Pediatric acute hypoxemic respiratory failure: management of oxygenation |
| Q48171782 | Perturbation of the pulmonary surfactant monolayer by single-walled carbon nanotubes: a molecular dynamics study. |
| Q29248541 | Physicochemical properties of nanoparticles regulate translocation across pulmonary surfactant monolayer and formation of lipoprotein corona |
| Q44082337 | Pilot study exploring lung allograft surfactant protein A (SP-A) expression in association with lung transplant outcome. |
| Q21284421 | Pneumocystis murina colonization in immunocompetent surfactant protein A deficient mice following environmental exposure |
| Q57987138 | Pneumovirus and Metapneumovirus: Respiratory Syncytial Virus and Human Metapneumovirus |
| Q44410855 | Protective effects of a recombinant fragment of human surfactant protein D in a murine model of pulmonary hypersensitivity induced by dust mite allergens. |
| Q46788993 | Protective effects of elevated endogenous surfactant pools to injurious mechanical ventilation. |
| Q42282041 | Pulmonary collectins selectively permeabilize model bacterial membranes containing rough lipopolysaccharide. |
| Q80360636 | Pulmonary infections in swine induce altered porcine surfactant protein D expression and localization to dendritic cells in bronchial-associated lymphoid tissue |
| Q53689789 | Pulmonary surfactant promotes virulence gene expression and biofilm formation in Klebsiella pneumoniae. |
| Q44622869 | Pulmonary surfactant secretion in briefly cultured mouse type II cells |
| Q45192424 | Purification, characterization and immunolocalization of porcine surfactant protein D. |
| Q47769738 | Rare SP-A alleles and the SP-A1-6A(4) allele associate with risk for lung carcinoma |
| Q42051082 | Reactive oxygen species inactivation of surfactant involves structural and functional alterations to surfactant proteins SP-B and SP-C. |
| Q27687743 | Respiratory epithelial cells orchestrate pulmonary innate immunity |
| Q40572941 | Respiratory epithelial cells regulate lung inflammation in response to inhaled endotoxin |
| Q37737843 | Review: Structural determinants of pattern recognition by lung collectins. |
| Q53424800 | Role of clathrin-mediated endocytosis of surfactant protein A by alveolar macrophages in intracellular signaling. |
| Q38376217 | Role of genetics in lung transplant complications |
| Q21284414 | SP-A binds alpha1-antitrypsin in vitro and reduces the association rate constant for neutrophil elastase. |
| Q43494673 | Secreted surfactant protein A from fetal membranes induces stress fibers in cultured human myometrial cells |
| Q48390757 | Selective medicated (saline + natural surfactant) bronchoalveolar lavage in unilateral lung contusion. A clinical randomized controlled trial. |
| Q36387278 | Serum Lipoproteins Are Critical for Pulmonary Innate Defense against Staphylococcus aureus Quorum Sensing |
| Q38619894 | Strains of Mycobacterium tuberculosis differ in affinity for human osteoblasts and alveolar cells in vitro |
| Q91650234 | Study on the Relationship Between Respiratory Distress Syndrome and SP-A1 (rs1059057) Gene Polymorphism in Mongolian Very Premature Infants |
| Q46895670 | Surfactant as an airway smooth muscle relaxant |
| Q24203694 | Surfactant for bacterial pneumonia in late preterm and term infants |
| Q89678060 | Surfactant protein A expression and distribution in human lung samples from smokers with or without chronic obstructive pulmonary disease in China |
| Q33991198 | Surfactant protein A2 mutations associated with pulmonary fibrosis lead to protein instability and endoplasmic reticulum stress. |
| Q35950137 | Surfactant protein B inhibits secretory phospholipase A2 hydrolysis of surfactant phospholipids |
| Q28273398 | Surfactant protein D alters allergic lung responses in mice and human subjects |
| Q40186820 | Surfactant protein D interacts with alpha2-macroglobulin and increases its innate immune potential. |
| Q41944326 | Surfactant protein D regulates the cell surface expression of alveolar macrophage beta(2)-integrins |
| Q34758548 | Surfactant protein-A (SP-A) selectively inhibits prostaglandin F2alpha (PGF2alpha) production in term decidua: implications for the onset of labor. |
| Q33868606 | Surfactant protein-d inhibits lung inflammation caused by ventilation in premature newborn lambs |
| Q34197408 | Surfactant proteins A and D inhibit the growth of Gram-negative bacteria by increasing membrane permeability |
| Q47833760 | TGF-alpha perturbs surfactant homeostasis in vivo |
| Q36880253 | The Oxygen Environment at Birth Specifies the Population of Alveolar Epithelial Stem Cells in the Adult Lung |
| Q28388253 | The Pulmonary Surfactant: Impact of Tobacco Smoke and Related Compounds on Surfactant and Lung Development |
| Q35668315 | The Role of ExoS in Dissemination of Pseudomonas aeruginosa during Pneumonia |
| Q36163743 | The concentration of surfactant protein-A in amniotic fluid decreases in spontaneous human parturition at term |
| Q46734438 | The effect of repeated umbilical cord occlusions on pulmonary surfactant protein mRNA levels in the ovine fetus. |
| Q28504661 | The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens |
| Q51793892 | The impact of chemokine receptor CX3CR1 deficiency during respiratory infections with Mycobacterium tuberculosis or Francisella tularensis. |
| Q33835843 | The molecular basis of pulmonary alveolar proteinosis |
| Q33942221 | The molecular era of surfactant biology |
| Q28388325 | The pulmonary surfactant: impact of tobacco smoke and related compounds on surfactant and lung development |
| Q47141783 | The role of natural processes and surface energy of inhaled engineered nanoparticles on aggregation and corona formation |
| Q24629135 | The untranslated exon B of human surfactant protein A2 mRNAs is an enhancer for transcription and translation |
| Q61445740 | Time-resolved proteome profiling of normal lung development |
| Q36347862 | Toll-like receptor 2 (TLR2), transforming growth factor-β, hyaluronan (HA), and receptor for HA-mediated motility (RHAMM) are required for surfactant protein A-stimulated macrophage chemotaxis |
| Q34390661 | Transcriptional programs controlling perinatal lung maturation |
| Q37357690 | Transcriptional responses of Mycobacterium tuberculosis to lung surfactant |
| Q52726359 | Ultrastructure of Highly Ordered Granules in Alveolar Type II Cells in Several Species. |
| Q34111696 | Variations in Helicobacter pylori lipopolysaccharide to evade the innate immune component surfactant protein D. |
| Q82391290 | [Value of surfactant replacement therapy in the treatment of acute respiratory distress syndrome] |
| Q35879501 | rIL-10 enhances IL-10 signalling proteins in foetal alveolar type II cells exposed to hyperoxia |
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