scholarly article | Q13442814 |
P356 | DOI | 10.1016/S1470-2045(01)00622-2 |
P698 | PubMed publication ID | 11905606 |
P2093 | author name string | Seiji Yano | |
Corazon D Bucana | |||
Isaiah J Fidler | |||
Ruo-Dan Zhang | |||
Takahashi Fujimaki | |||
P2860 | cites work | Quantitative study of microvessel ultrastructure in human peritumoral brain tissue. Evidence for a blood-brain barrier defect | Q48186495 |
The blood-brain barrier redefined | Q48313750 | ||
The importance of brain temperature in alterations of the blood-brain barrier following cerebral ischemia. | Q48903817 | ||
Brain uptake and anticancer activities of vincristine and vinblastine are restricted by their low cerebrovascular permeability and binding to plasma constituents in rat. | Q49154018 | ||
Angiogenesis and blood-brain barrier breakdown modulate CT contrast enhancement: an experimental study in a rabbit brain-tumor model | Q50887606 | ||
The endothelial hyperplasia of the cerebral blood vessels with brain tumors, and its sarcomatous transformation | Q51322265 | ||
Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. | Q55476886 | ||
Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells | Q67590241 | ||
Metastasis results from preexisting variant cells within a malignant tumor | Q67602509 | ||
Intussusceptive microvascular growth in a human colon adenocarcinoma xenograft: a novel mechanism of tumor angiogenesis | Q71459931 | ||
Surgical treatment of metastatic brain tumors | Q71629204 | ||
Evidence for the clonal origin of spontaneous metastases | Q72041683 | ||
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation | Q24642901 | ||
Angiogenesis in cancer and other diseases | Q27861015 | ||
TIE1 and TIE2 Receptor Tyrosine Kinases Inversely Regulate Embryonic Angiogenesis by the Mechanism of Intussusceptive Microvascular Growth | Q28512487 | ||
Mechanisms of angiogenesis | Q29547485 | ||
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene | Q29547732 | ||
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele | Q29547733 | ||
The distribution of secondary growths in cancer of the breast. 1889 | Q29614314 | ||
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid | Q29617640 | ||
VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain | Q30936721 | ||
Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells | Q34047111 | ||
Delivery of molecular and cellular medicine to solid tumors | Q34190339 | ||
The relation between cell proliferation and the vascular system in a transplanted mouse mammary tumour | Q36037858 | ||
Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation | Q36618743 | ||
Intracerebral tumor-associated hemorrhage caused by overexpression of the vascular endothelial growth factor isoforms VEGF 121 and VEGF 165 but not VEGF 189 | Q36636478 | ||
The physiology of the blood-brain barrier. | Q37990987 | ||
Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis | Q40377374 | ||
Modulation of the organ microenvironment for treatment of cancer metastasis | Q40415645 | ||
Antibody-directed targeting of the vasculature of solid tumors | Q40930942 | ||
Clonal origin of metastasis in B16 murine melanoma: a cytogenetic study | Q43417858 | ||
Development ofin vivo models for studies of brain metastasis | Q48088030 | ||
P433 | issue | 1 | |
P304 | page(s) | 53-57 | |
P577 | publication date | 2002-01-01 | |
P13046 | publication type of scholarly work | review article | Q7318358 |
P1433 | published in | Lancet Oncology Commission | Q13747613 |
P1476 | title | The seed and soil hypothesis: vascularisation and brain metastases | |
P478 | volume | 3 |
Q33840723 | "Pre-metastatic niches" in breast cancer: are they created by or prior to the tumour onset? "Flammer Syndrome" relevance to address the question. |
Q94465319 | A Pilot Study: N-Staging Assessment of Shear Wave Elastrography in Small Cervical Lymph Nodes for Nasopharyngeal Carcinoma |
Q34000987 | A Review of Current Management of Brain Metastases |
Q44496375 | A novel concept of glomeruloid body formation in experimental cerebral metastases |
Q73245873 | A novel rodent mammary window of orthotopic breast cancer for intravital microscopy |
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Q27322772 | An Integrative Platform for Three-dimensional Quantitative Analysis of Spatially Heterogeneous Metastasis Landscapes |
Q42824566 | An experimental study on the Chinese lung adenocarcinoma cell clone CPA-Yang1-BR with brain metastasis potency in nude mice and in vivo imaging research |
Q60895177 | Analysis of nanoparticle delivery to tumours |
Q36887534 | Angiogenesis in brain tumours |
Q38034321 | Angiogenesis in neurological disorders: a review |
Q38985337 | Anti-angiogenetic therapies for central nervous system metastases from non-small cell lung cancer. |
Q37187003 | Antibody tumor penetration: transport opposed by systemic and antigen-mediated clearance. |
Q34457363 | Apoptotic cells initiate endothelial cell sprouting via electrostatic signaling |
Q57176317 | Barriers to Effective Drug Treatment for Brain Metastases: A Multifactorial Problem in the Delivery of Precision Medicine |
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Q34770149 | Detection and isolation of circulating tumor cells in urologic cancers: a review |
Q36820588 | Development of a preclinical therapeutic model of human brain metastasis with chemoradiotherapy. |
Q27023250 | Developmental and pathological angiogenesis in the central nervous system |
Q48130398 | Diagnostic examination performance by using microvascular leakage, cerebral blood volume, and blood flow derived from 3-T dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging in the differentiation of glioblastoma multiforme and br |
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Q39519242 | Dual targeting effect of Angiopep-2-modified, DNA-loaded nanoparticles for glioma |
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Q52591097 | Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors for Central Nervous System Metastases from Non-Small Cell Lung Cancer. |
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Q28084034 | Epidermal growth factor signaling in transformed cells |
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Q78708143 | Evidence for the causal role of endogenous interferon-alpha/beta in the regulation of angiogenesis, tumorigenicity, and metastasis of cutaneous neoplasms |
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Q33685045 | Extracerebral metastases determine the outcome of patients with brain metastases from renal cell carcinoma. |
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