| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | S Hoyer | |
| K Maurer | |||
| P2860 | cites work | Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors | Q24294213 |
| The PI3K-PDK1 connection: more than just a road to PKB | Q24531972 | ||
| Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo | Q24683214 | ||
| Self-organized criticality | Q27339350 | ||
| Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B | Q27860731 | ||
| The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics | Q27860914 | ||
| Lipid rafts and signal transduction | Q28131735 | ||
| The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses | Q28142887 | ||
| Apolipoprotein E: far more than a lipid transport protein | Q28204471 | ||
| Minireview: 11beta-hydroxysteroid dehydrogenase type 1- a tissue-specific amplifier of glucocorticoid action | Q28204909 | ||
| GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides | Q28205921 | ||
| Corticosteroids and cognition | Q28207453 | ||
| Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme | Q28254283 | ||
| Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation | Q28280708 | ||
| Levels of phospholipid catabolic intermediates, glycerophosphocholine and glycerophosphoethanolamine, are elevated in brains of Alzheimer's disease but not of Down's syndrome patients | Q28330180 | ||
| Evidence for a membrane defect in Alzheimer disease brain | Q28343061 | ||
| Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme | Q28582802 | ||
| Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation | Q28613091 | ||
| Proteomic characterisation of neuronal sphingolipid-cholesterol microdomains: role in plasminogen activation | Q28909779 | ||
| Oxidative energy metabolism in Alzheimer brain | Q29305906 | ||
| Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls | Q29547730 | ||
| Protein folding in the cell | Q29547792 | ||
| Molecular dissection of the secretory pathway | Q29618201 | ||
| Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes? | Q29619535 | ||
| Protein sorting by transport vesicles | Q29619990 | ||
| The protein machinery of vesicle budding and fusion | Q30424702 | ||
| Abnormal processing of multiple proteins in Alzheimer disease | Q30450830 | ||
| Membrane breakdown in acute and chronic neurodegeneration: focus on choline-containing phospholipids | Q30617789 | ||
| Altered phosphofructokinase mRNA levels but unchanged isoenzyme pattern in brains from patients with Alzheimer's disease | Q30857378 | ||
| Copernicus revisited: amyloid beta in Alzheimer's disease | Q31867854 | ||
| Effect of ATP depletion and DTT on the transport of membrane proteins from the endoplasmic reticulum and the intermediate compartment to the Golgi complex | Q44769402 | ||
| Increased caveolin-1 expression in Alzheimer's disease brain | Q44912484 | ||
| Structural membrane alterations in Alzheimer brains found to be associated with regional disease development; increased density of gangliosides GM1 and GM2 and loss of cholesterol in detergent-resistant membrane domains | Q45192504 | ||
| Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain | Q45304576 | ||
| Mitochondrial abnormalities in Alzheimer brain: mechanistic implications | Q46456103 | ||
| Regulation of the Na+/K+-ATPase by insulin: why and how? | Q48021636 | ||
| Insulin signal transduction through protein kinase cascades | Q48021735 | ||
| Insulin gene expression and insulin synthesis in mammalian neuronal cells | Q48084097 | ||
| Short-term or long-term intracerebroventricular (i.c.v.) infusion of insulin exhibits a discrete anabolic effect on cerebral energy metabolism in the rat. | Q48090329 | ||
| Evidence of glutamatergic denervation and possible abnormal metabolism in Alzheimer's disease | Q48105069 | ||
| Electron transport chain defects in Alzheimer's disease brain | Q48107929 | ||
| Activities of key glycolytic enzymes in the brains of patients with Alzheimer's disease | Q48139350 | ||
| Membrane lipids, selectively diminished in Alzheimer brains, suggest synapse loss as a primary event in early-onset form (type I) and demyelination in late-onset form (type II). | Q48164740 | ||
| Altered cerebral energy metabolism in Alzheimer's disease: a PET study. | Q48197690 | ||
| Clinical deterioration in probable Alzheimer's disease correlates with progressive metabolic impairment of association areas. | Q48204408 | ||
| Evidence of an insulin generated pyruvate dehydrogenase stimulating factor in rat brain plasma membranes | Q48247364 | ||
| Stimulation of glycolytic key enzymes in cerebral cortex by insulin | Q48254912 | ||
| Failure to maintain glycolysis in anoxic nerve terminals | Q48272530 | ||
| Increased activity of surviving locus ceruleus neurons in Alzheimer's disease | Q48302893 | ||
| Positron emission tomography in Alzheimer's disease | Q48328045 | ||
| Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau. | Q48394153 | ||
| Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease | Q48404181 | ||
| Is sporadic Alzheimer disease the brain type of non-insulin dependent diabetes mellitus? A challenging hypothesis | Q48404189 | ||
| Lipid composition in different regions of the brain in Alzheimer's disease/senile dementia of Alzheimer's type | Q48414438 | ||
| Developmental regulation of insulin in the mammalian central nervous system | Q48469988 | ||
| GM1 ganglioside-bound amyloid beta-protein in Alzheimer's disease brain | Q48482717 | ||
| Evidence for changes in the Alzheimer's disease brain cortical membrane structure mediated by cholesterol | Q48482911 | ||
| Degradation of membrane phospholipids in the cultured human astroglial cell line UC-11MG during ATP depletion | Q41566305 | ||
| Aging, memory, and the cholinergic system: a study of dichotic listening | Q41637129 | ||
| Mechanism of activation and function of protein kinase B. | Q41732739 | ||
| Decreased synthesis of acetylcholine accompanying impaired oxidation of pyruvic acid in rat brain minces | Q41816374 | ||
| Two novel kinases phosphorylate tau and the KSP site of heavy neurofilament subunits in high stoichiometric ratios | Q41834025 | ||
| Neuronal membrane cholesterol loss enhances amyloid peptide generation | Q41967267 | ||
| Amyloid precursor protein, although partially detergent-insoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein | Q42052497 | ||
| Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway | Q42164668 | ||
| In vivo regulation of amyloid precursor protein secretion in rat neocortex by cholinergic activity | Q42449011 | ||
| Enhanced O-GlcNAc protein modification is associated with insulin resistance in GLUT1-overexpressing muscles | Q42523492 | ||
| Changes in membrane properties during energy depletion-induced cell injury studied with fluorescence microscopy | Q42536089 | ||
| Inhibition of cholesterol production but not of nonsterol isoprenoid products induces neuronal cell death | Q42815097 | ||
| Decreased tyrosine kinase activity of insulin receptor isolated from rat adipocytes rendered insulin-resistant by catecholamine treatment in vitro | Q42852817 | ||
| Increased CSF cortisol in AD is a function of APOE genotype. | Q43587037 | ||
| Insulin action rapidly decreases multifunctional protein kinase activity in rat adipose tissue | Q43648874 | ||
| Reciprocity between O-GlcNAc and O-phosphate on the carboxyl terminal domain of RNA polymerase II. | Q43652827 | ||
| Tangle-bearing neurons contain more free cholesterol than adjacent tangle-free neurons. | Q43714720 | ||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase mRNA in Alzheimer and control brain | Q43757899 | ||
| CNS synaptogenesis promoted by glia-derived cholesterol | Q43794738 | ||
| Predominant abnormality in cerebral glucose utilization in late-onset dementia of the Alzheimer type: a cross-sectional comparison against advanced late-onset and incipient early-onset cases | Q43828915 | ||
| Cholesterol attenuates the membrane perturbing properties of beta-amyloid peptides | Q44199468 | ||
| Cortisol and dehydroepiandosterone sulfate plasma levels and their relationship to aging, cognitive function, and dementia | Q44237329 | ||
| Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PET. | Q44249033 | ||
| Evidence that neurones accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer's disease | Q32028060 | ||
| Intracellular cholesterol transport. | Q33601463 | ||
| Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives | Q33707601 | ||
| Protein dissociation from GRP78 and secretion are blocked by depletion of cellular ATP levels | Q33811520 | ||
| Glucocorticoid regulation of insulin receptor and substrate IRS-1 tyrosine phosphorylation in rat skeletal muscle in vivo | Q33898881 | ||
| Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling. | Q33942765 | ||
| Early-life programming of susceptibility to dysregulation of glucose metabolism and the development of Type 2 diabetes mellitus | Q33973721 | ||
| Membrane lipid composition and cellular function | Q34051085 | ||
| Insulin stimulates choline acetyltransferase activity in cultured embryonic chicken retina neurons | Q34357382 | ||
| New frontiers in Alzheimer's disease genetics | Q34421591 | ||
| Endoplasmic reticulum dysfunction--a common denominator for cell injury in acute and degenerative diseases of the brain? | Q34448730 | ||
| Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine | Q34474707 | ||
| The cholinergic pathology in Alzheimer's disease--discrepancies between clinical experience and pathophysiological findings | Q34732610 | ||
| Reduced glucose tolerance is associated with poor memory performance and hippocampal atrophy among normal elderly | Q34763045 | ||
| The role of the metabolic lesion in Alzheimer's disease. | Q34844638 | ||
| The source of cerebral insulin | Q35749604 | ||
| Intraneuronal Abeta42 accumulation in human brain. | Q35793325 | ||
| Thematic review series: brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal | Q35836597 | ||
| Cholesterol homeostasis in neurons and glial cells | Q36083624 | ||
| Impaired brain glucose metabolism leads to Alzheimer neurofibrillary degeneration through a decrease in tau O-GlcNAcylation. | Q36455090 | ||
| Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease | Q36604677 | ||
| Prevalence of Alzheimer's disease and vascular dementia: association with education. The Rotterdam study | Q36903154 | ||
| Insulin in the cerebrospinal fluid | Q37181592 | ||
| Differential effects of electrical stimulation of sciatic nerve on metabolic activity in spinal cord and dorsal root ganglion in the rat. | Q37532084 | ||
| Insulin and insulin-like growth factor receptors in the nervous system | Q38296571 | ||
| ATP and brain function | Q38597443 | ||
| Senile dementia and Alzheimer's disease. Brain blood flow and metabolism | Q39753002 | ||
| Cerebral blood flow and metabolism in normal human aging, pathological aging, and senile dementia | Q39856970 | ||
| Phospholipid Methylation and Biological Signal Transmission | Q40098375 | ||
| Non-equilibrium dynamics of biochemical processes. 8. Fritz Lipmann-Vorlesung | Q40147858 | ||
| Localization of functional activity in the central nervous system by measurement of glucose utilization with radioactive deoxyglucose | Q40324066 | ||
| Cholinergic Neural Regulation of Regional Cerebral Blood Flow | Q40441423 | ||
| Brain Cholesterol, Statins and Alzheimer’s Disease | Q40623764 | ||
| Increased A beta peptides and reduced cholesterol and myelin proteins characterize white matter degeneration in Alzheimer's disease | Q40634928 | ||
| Impaired cerebral glucose metabolism and cognitive functioning predict deterioration in mild cognitive impairment | Q40716303 | ||
| Cholesterol-dependent formation of GM1 ganglioside-bound amyloid beta-protein, an endogenous seed for Alzheimer amyloid | Q40807391 | ||
| Regulation of insulin receptor signaling by protein-tyrosine dephosphorylation | Q40856641 | ||
| Dynamic O-linked glycosylation of nuclear and cytoskeletal proteins | Q40912257 | ||
| Raft disorganization leads to reduced plasmin activity in Alzheimer's disease brains | Q41011680 | ||
| Fatty acid composition of brain phospholipids in aging and in Alzheimer's disease | Q41159549 | ||
| Recent advances in membrane cholesterol domain dynamics and intracellular cholesterol trafficking | Q41226568 | ||
| Distribution of insulin receptor-like immunoreactivity in the rat forebrain | Q41321702 | ||
| Direct measurement of trans-Golgi pH in living cells and regulation by second messengers | Q41360787 | ||
| Phospholipid-metabolizing enzymes in Alzheimer's disease: increased lysophospholipid acyltransferase activity and decreased phospholipase A2 activity | Q48546991 | ||
| Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype | Q48555125 | ||
| Cortical abnormalities in Alzheimer's disease | Q48597181 | ||
| Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease | Q48671019 | ||
| Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide: role of the lipid peroxidation product 4-hydroxynonenal | Q48677217 | ||
| Metabolic processes in Alzheimer's disease: adenine nucleotide content and production of 14CO2 from [U-14C]glucose in vitro in human neocortex | Q48720709 | ||
| Structural differences between insulin receptors in the brain and peripheral target tissues. | Q48773634 | ||
| Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: involvement of insulin-degrading enzyme | Q48812317 | ||
| Changes of activity and isozyme pattern of phosphofructokinase in the brains of patients with Alzheimer's disease. | Q48938677 | ||
| Cortisol and Alzheimer's disease, I: Basal studies | Q49016718 | ||
| Increasing age alters transbilayer fluidity and cholesterol asymmetry in synaptic plasma membranes of mice | Q49043023 | ||
| Cerebral metabolism of isotopic glucose in normal human subjects. | Q51328533 | ||
| Insulin metabolism in Alzheimer's disease differs according to apolipoprotein E genotype and gender. | Q51561458 | ||
| Changes in blood glucose and insulin secretion in patients with senile dementia of Alzheimer type. | Q51648669 | ||
| Cerebrospinal fluid epinephrine in Alzheimer's disease and normal aging. | Q51989980 | ||
| Decreased phospholipase A2 activity in Alzheimer brains. | Q52019953 | ||
| Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported. | Q52112673 | ||
| Cholesterol modulates the membrane-disordering effects of beta-amyloid peptides in the hippocampus: specific changes in Alzheimer's disease. | Q52539745 | ||
| In vivo 31P NMR profiles of Alzheimer's disease and multiple subcortical infarct dementia. | Q53189485 | ||
| Coenzyme a-acetylating enzymes in Alzheimer's disease: Possible cholinergic ‘compartment’ of pyruvate dehydrogenase | Q53196480 | ||
| Presynaptic cholinergic dysfunction in patients with dementia. | Q53198289 | ||
| GM1 ganglioside-bound amyloid beta-protein (A beta): a possible form of preamyloid in Alzheimer's disease. | Q53199612 | ||
| Effects of Alzheimer's Disease and Normal Aging on Cerebrospinal Fluid Norepinephrine Responses to Yohimbine and Clonidine | Q53201317 | ||
| Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons. | Q53218504 | ||
| The phosphatidylinositol 3-kinase inhibitor wortmannin alters the metabolism of the Alzheimer's amyloid precursor protein. | Q53231712 | ||
| Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains. | Q53234549 | ||
| Hypothalamic pituitary adrenocortical and sympathetic nervous system responses to the cold pressor test in Alzheimer's disease. | Q53236804 | ||
| 31P Nuclear Magnetic Resonance Study of the Brain in Alzheimerʼs Disease | Q53304910 | ||
| Membrane disruption by Alzheimer beta-amyloid peptides mediated through specific binding to either phospholipids or gangliosides. Implications for neurotoxicity. | Q53323047 | ||
| Glucocorticoid-related genetic susceptibility for Alzheimer's disease. | Q53361460 | ||
| Structural transitions associated with the interaction of Alzheimer beta-amyloid peptides with gangliosides. | Q54144813 | ||
| Role of ATP and disulphide bonds during protein folding in the endoplasmic reticulum | Q59053405 | ||
| Increased Cortisol Levels in Aging and Alzheimer's Disease in Postmortem Cerebrospinal Fluid | Q59449663 | ||
| Glycogen synthase kinase 3β is identical to tau protein kinase I generating several epitopes of paired helical filaments | Q59488574 | ||
| Changes in brain membrane phospholipid and high-energy phosphate metabolism precede dementia | Q60452027 | ||
| Mitochondrial and peroxisomal beta-oxidation of stearic and lignoceric acids by rat brain | Q69788336 | ||
| The amino acid metabolism in normal human brain | Q71721023 | ||
| Glucose and amino acid metabolism in rat brain during sustained hypoglycemia | Q71837404 | ||
| Brain alpha-ketoglutarate dehydrogenase complex activity in Alzheimer's disease | Q72621570 | ||
| Insulin activates protein kinase B, inhibits glycogen synthase kinase-3 and activates glycogen synthase by rapamycin-insensitive pathways in skeletal muscle and adipose tissue | Q73241292 | ||
| Insulin regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathway | Q73716344 | ||
| Mechanism of acidification of the trans-Golgi network (TGN). In situ measurements of pH using retrieval of TGN38 and furin from the cell surface | Q74088770 | ||
| Insulin and glucosamine infusions increase O-linked N-acetyl-glucosamine in skeletal muscle proteins in vivo | Q74460507 | ||
| Experimental study of critical-mass fluctuations in an evolving sandpile | Q74506177 | ||
| THE CARBOHYDRATE METABOLISM OF THE HUMAN BRAIN. I. STUDIES WITH SUBSTRATE-SPECIFIC ENZYMATIC METHODS IN NORMAL BRAIN CIRCULATION | Q76679442 | ||
| Insulin transiently increases tau phosphorylation: involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase | Q77944438 | ||
| P433 | issue | 11 | |
| P921 | main subject | Alzheimer's disease | Q11081 |
| Alois Alzheimer | Q70530 | ||
| P304 | page(s) | 1645-1658 | |
| P577 | publication date | 2006-10-23 | |
| P1433 | published in | Journal of Neural Transmission | Q15750921 |
| P1476 | title | Alois Alzheimer revisited: differences in origin of the disease carrying his name | |
| P478 | volume | 113 |
| Q41877527 | Aging and neurogenesis, a lesion from Alzheimer's disease. |
| Q38820863 | Alzheimer's Disease Risk Genes and Lipid Regulators. |
| Q40361355 | Cardiovascular dementia - a different perspective |
| Q35698618 | Differential cerebral deposition of IDE and NEP in sporadic and familial Alzheimer's disease |
| Q36629895 | From benefit to damage. Glutamate and advanced glycation end products in Alzheimer brain |
| Q46914423 | Long-term abnormalities in brain glucose/energy metabolism after inhibition of the neuronal insulin receptor: implication of tau-protein. |
| Q46446421 | Long-term effects of corticosterone on behavior, oxidative and energy metabolism of parietotemporal cerebral cortex and hippocampus of rats: comparison to intracerebroventricular streptozotocin |
| Q37026742 | Neurotoxicity in Alzheimer's disease: is covalently crosslinked A beta responsible? |
| Q26770041 | Prediabetes and Alzheimer's Disease |
| Q47831375 | The Implication of the Brain Insulin Receptor in Late Onset Alzheimer's Disease Dementia. |
| Q90263981 | The Involvement of Peripheral and Brain Insulin Resistance in Late Onset Alzheimer's Dementia |
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