Human RNase H1 discriminates between subtle variations in the structure of the heteroduplex substrate

scientific article

Human RNase H1 discriminates between subtle variations in the structure of the heteroduplex substrate is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1124/MOL.106.025015
P698PubMed publication ID17028158

P2093author name stringStanley T Crooke
Hongjiang Wu
Walt F Lima
Michael T Migawa
John B Rose
Tadeusz K Wyrzykiewicz
Andrew M Siwkowski
Josh G Nichols
P433issue1
P304page(s)83-91
P577publication date2006-10-06
P1433published inMolecular PharmacologyQ1943386
P1476titleHuman RNase H1 discriminates between subtle variations in the structure of the heteroduplex substrate
P478volume71

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cites work (P2860)
Q390944825'-O-Methylphosphonate nucleic acids--new modified DNAs that increase the Escherichia coli RNase H cleavage rate of hybrid duplexes.
Q58794742A two-nuclease pathway involving RNase H1 is required for primer removal at human mitochondrial OriL
Q64951048A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.
Q35315759Antisense oligonucleotides capable of promoting specific target mRNA reduction via competing RNase H1-dependent and independent mechanisms
Q27007056Antisense oligonucleotides: treating neurodegeneration at the level of RNA
Q92152821Characterization of the Prion Protein Binding Properties of Antisense Oligonucleotides
Q52758305Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides.
Q37031903DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing
Q35721274Dissecting the target specificity of RNase H recruiting oligonucleotides using massively parallel reporter analysis of short RNA motifs.
Q36893517Effects of local mRNA structure on posttranscriptional gene silencing
Q33931423Evaluation of multiple-turnover capability of locked nucleic acid antisense oligonucleotides in cell-free RNase H-mediated antisense reaction and in mice
Q90455698Evolutionary history and activity of RNase H1-like proteins in Arabidopsis thaliana
Q39141872Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts
Q91698981Hybridization-mediated off-target effects of splice-switching antisense oligonucleotides
Q42286258Influence of mismatched and bulged nucleotides on SNP-preferential RNase H cleavage of RNA-antisense gapmer heteroduplexes.
Q24336833Involvement of DNA ligase III and ribonuclease H1 in mitochondrial DNA replication in cultured human cells
Q34528068MGME1 processes flaps into ligatable nicks in concert with DNA polymerase γ during mtDNA replication
Q38828951Managing the sequence-specificity of antisense oligonucleotides in drug discovery
Q42293314Molecular Mechanisms of Antisense Oligonucleotides
Q34221351Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene / allele-specific silencing of mutant huntingtin
Q26797996Primer removal during mammalian mitochondrial DNA replication
Q89820802RNase H1 Regulates Mitochondrial Transcription and Translation via the Degradation of 7S RNA
Q60921976RNase H1 directs origin-specific initiation of DNA replication in human mitochondria
Q35598590RNase HI Is Essential for Survival of Mycobacterium smegmatis
Q37327574Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS.
Q28828761Ribonuclease H1-dependent hepatotoxicity caused by locked nucleic acid-modified gapmer antisense oligonucleotides
Q34948246Ribonuclease H: the enzymes in eukaryotes
Q27660411Structural and Functional Characterization of an RNase HI Domain from the Bifunctional Protein Rv2228c from Mycobacterium tuberculosis
Q34448026Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkages.
Q38110692Targeting long non-coding RNA to therapeutically upregulate gene expression
Q28485228The hepatitis B virus ribonuclease H is sensitive to inhibitors of the human immunodeficiency virus ribonuclease H and integrase enzymes
Q92933262Understanding the effect of controlling phosphorothioate chirality in the DNA gap on the potency and safety of gapmer antisense oligonucleotides

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