Acute atrial arrhythmogenicity and altered Ca(2+) homeostasis in murine RyR2-P2328S hearts

scientific article

Acute atrial arrhythmogenicity and altered Ca(2+) homeostasis in murine RyR2-P2328S hearts is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/CVR/CVQ229
P932PMC publication ID3039245
P698PubMed publication ID20621925
P5875ResearchGate publication ID45150975

P2093author name stringMing Lei
James A Fraser
Yanmin Zhang
Christopher L-H Huang
Andrew A Grace
Kamalan Jeevaratnam
Sandeep S Hothi
Xiaojin Hao
P2860cites workAbsence of calsequestrin 2 causes severe forms of catecholaminergic polymorphic ventricular tachycardiaQ78390804
Expanding spectrum of human RYR2-related disease: new electrocardiographic, structural, and genetic featuresQ24294249
KCNQ1 gain-of-function mutation in familial atrial fibrillationQ24338486
Catecholaminergic polymorphic ventricular tachycardia: electrocardiographic characteristics and optimal therapeutic strategies to prevent sudden deathQ24674590
Mutations of the cardiac ryanodine receptor (RyR2) gene in familial polymorphic ventricular tachycardiaQ28142708
Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardiaQ28201561
A missense mutation in a highly conserved region of CASQ2 is associated with autosomal recessive catecholamine-induced polymorphic ventricular tachycardia in Bedouin families from IsraelQ28204838
Catecholaminergic polymorphic ventricular tachycardiaQ28287523
Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in miceQ30488460
Arrhythmic disorder mapped to chromosome 1q42-q43 causes malignant polymorphic ventricular tachycardia in structurally normal heartsQ33145152
Clinical and molecular characterization of patients with catecholaminergic polymorphic ventricular tachycardia.Q33147854
Bidirectional ventricular tachycardia and fibrillation elicited in a knock-in mouse model carrier of a mutation in the cardiac ryanodine receptor.Q33152686
Catecholaminergic polymorphic ventricular tachycardia in children. A 7-year follow-up of 21 patientsQ33173888
Acute atrial arrhythmogenesis in murine hearts following enhanced extracellular Ca(2+) entry depends on intracellular Ca(2+) stores.Q33514742
Pharmacological changes in cellular Ca2+ homeostasis parallel initiation of atrial arrhythmogenesis in murine Langendorff-perfused hearts.Q33739827
Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2.Q34312242
Calstabin deficiency, ryanodine receptors, and sudden cardiac deathQ35874314
Mechanisms of atrial remodeling and clinical relevance.Q35982796
Mechanisms of atrial fibrillation: lessons from animal models.Q36272316
Inherited arrhythmias: a National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutationQ36999467
Physiological consequences of the P2328S mutation in the ryanodine receptor (RyR2) gene in genetically modified murine heartsQ37066411
Atrial arrhythmogenesis in wild-type and Scn5a+/delta murine hearts modelling LQT3 syndromeQ37214708
Calcium handling abnormalities in atrial fibrillation as a target for innovative therapeutics.Q37268790
Cardiac gene defects can cause sudden cardiac death in young peopleQ37535546
Atrial remodeling and atrial fibrillation: mechanisms and implications.Q37609710
Catecholaminergic polymorphic ventricular tachycardia: RYR2 mutations, bradycardia, and follow up of the patients.Q43073409
Atrial Ca2+ signaling in atrial fibrillation as an antiarrhythmic drug targetQ43270475
Effects of avertin versus xylazine-ketamine anesthesia on cardiac function in normal miceQ43773122
Association of atrial arrhythmia and sinus node dysfunction in patients with catecholaminergic polymorphic ventricular tachycardiaQ46981935
Measurement of heart rate and Q-T interval in the conscious mouse.Q50898283
Familial polymorphic ventricular arrhythmias: a quarter century of successful medical treatment based on serial exercise-pharmacologic testingQ73250272
P433issue4
P304page(s)794-804
P577publication date2010-07-09
P1433published inCardiovascular ResearchQ4642329
P1476titleAcute atrial arrhythmogenicity and altered Ca(2+) homeostasis in murine RyR2-P2328S hearts
P478volume89

Reverse relations

cites work (P2860)
Q36952000Abnormal Ca(2+) homeostasis, atrial arrhythmogenesis, and sinus node dysfunction in murine hearts modeling RyR2 modification
Q48287484Age-dependent electrocardiographic changes in Pgc-1β deficient murine hearts.
Q38039083An introduction to murine models of atrial fibrillation
Q54440604Atrial arrhythmia, triggering events and conduction abnormalities in isolated murine RyR2-P2328S hearts.
Q47099943Effects of ageing on pro-arrhythmic ventricular phenotypes in incrementally paced murine Pgc-1β -/- hearts
Q41910718Flecainide exerts paradoxical effects on sodium currents and atrial arrhythmia in murine RyR2-P2328S hearts.
Q58616505Gene and Protein Expression Profile of Selected Molecular Targets Mediating Electrophysiological Function in Deficient Murine Atria
Q64265892Identification of RyR2-PBmice and the effects of transposon insertional mutagenesis of the RyR2 gene on cardiac function in mice
Q35295864Imaging atrial arrhythmic intracellular calcium in intact heart
Q96576958Intracellular calcium leak in heart failure and atrial fibrillation: a unifying mechanism and therapeutic target
Q50490336Loss of Nav1.5 expression and function in murine atria containing the RyR2-P2328S gain-of-function mutation.
Q41458404Mitochondrial oxidative stress promotes atrial fibrillation
Q39038606Murine Electrophysiological Models of Cardiac Arrhythmogenesis
Q47136909Pro-arrhythmic atrial phenotypes in incrementally paced murine Pgc1β-/- hearts: effects of age.
Q51591524Slowed depolarization and irregular repolarization in catecholaminergic polymorphic ventricular tachycardia: a study from cellular Ca2+ transients and action potentials to clinical monophasic action potentials and electrocardiography.
Q36688514The RyR2-P2328S mutation downregulates Nav1.5 producing arrhythmic substrate in murine ventricles.
Q35215931The involvement of TRPC3 channels in sinoatrial arrhythmias

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