| review article | Q7318358 |
| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1031480740 |
| P356 | DOI | 10.1038/SJ.ONC.1210617 |
| P698 | PubMed publication ID | 17694090 |
| P5875 | ResearchGate publication ID | 6145630 |
| P2093 | author name string | Reinberg D | |
| Vaquero A | |||
| Sternglanz R | |||
| P2860 | cites work | Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity | Q22010164 |
| Translating the Histone Code | Q22065840 | ||
| Negative control of p53 by Sir2alpha promotes cell survival under stress | Q24291828 | ||
| hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase | Q24291829 | ||
| Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 and HEY2 and is involved in HES1- and HEY2-mediated transcriptional repression | Q24292887 | ||
| Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation | Q24293278 | ||
| Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses | Q24293580 | ||
| Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase | Q24293656 | ||
| Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2 | Q24294341 | ||
| Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma | Q24294948 | ||
| The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase | Q24296836 | ||
| Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase | Q24297207 | ||
| Human histone deacetylase SIRT2 interacts with the homeobox transcription factor HOXA10 | Q24297506 | ||
| Chromatin Fiber Folding: Requirement for the Histone H4 N-terminal Tail | Q61041700 | ||
| The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression | Q72863039 | ||
| Role of NAD(+) in the deacetylase activity of the SIR2-like proteins | Q73235501 | ||
| Histone H4 acetylation in plant heterochromatin is altered during the cell cycle | Q73536483 | ||
| Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage | Q24299098 | ||
| Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle | Q24299947 | ||
| SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells | Q24301843 | ||
| SIRT1 interacts with p73 and suppresses p73-dependent transcriptional activity | Q24304342 | ||
| Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF | Q24305335 | ||
| Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin | Q24306469 | ||
| Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase | Q24310456 | ||
| Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state | Q24312132 | ||
| SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis | Q24322664 | ||
| SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1 | Q24337470 | ||
| Involvement of human MOF in ATM function | Q24529072 | ||
| hMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cells | Q24529984 | ||
| A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16 | Q24534923 | ||
| SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria | Q24536184 | ||
| Histone deacetylases, acetoin utilization proteins and acetylpolyamine amidohydrolases are members of an ancient protein superfamily | Q24545263 | ||
| Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription | Q24545711 | ||
| Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications | Q24545952 | ||
| Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription | Q24546024 | ||
| Acetylation of histones and transcription-related factors | Q24548503 | ||
| The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase gcn5p | Q24596953 | ||
| ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS | Q24629431 | ||
| Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2-mediated transcriptional repression | Q24650557 | ||
| Altered sirtuin expression is associated with node-positive breast cancer | Q24652625 | ||
| SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress | Q24670578 | ||
| The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase | Q24671306 | ||
| Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein | Q24682617 | ||
| The diversity of acetylated proteins | Q24791823 | ||
| Crystal structure of a SIR2 homolog-NAD complex | Q27631591 | ||
| Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase | Q27860668 | ||
| Histone H4 acetylation of euchromatin and heterochromatin is cell cycle dependent and correlated with replication rather than with transcription | Q33926085 | ||
| Genomic characterization reveals a simple histone H4 acetylation code. | Q33935027 | ||
| Histone modifications: combinatorial complexity or cumulative simplicity? | Q33936701 | ||
| Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast | Q34164007 | ||
| Histone acetylation and deacetylation in yeast | Q34187792 | ||
| Differential histone H3 Lys-9 and Lys-27 methylation profiles on the X chromosome | Q34347293 | ||
| Histone variants meet their match | Q34390385 | ||
| Splicing regulates NAD metabolite binding to histone macroH2A. | Q34427553 | ||
| Epigenetic characterization of the early embryo with a chromatin immunoprecipitation protocol applicable to small cell populations | Q34536958 | ||
| Males absent on the first (MOF): from flies to humans. | Q34662262 | ||
| Conservation of deposition-related acetylation sites in newly synthesized histones H3 and H4. | Q34709355 | ||
| Genome-wide histone modifications: gaining specificity by preventing promiscuity | Q35021243 | ||
| The archaeal cell cycle: current issues | Q35106880 | ||
| The constantly changing face of chromatin | Q35170141 | ||
| Acetylpolyamine amidohydrolase from Mycoplana ramosa: gene cloning and characterization of the metal-substituted enzyme | Q35614171 | ||
| The interaction between FOXO and SIRT1: tipping the balance towards survival | Q35861621 | ||
| Structure and chemistry of the Sir2 family of NAD+-dependent histone/protein deactylases | Q35928378 | ||
| Do protein motifs read the histone code? | Q36017986 | ||
| Poly(ADP-ribose) polymerases: managing genome stability | Q36060144 | ||
| Resveratrol improves health and survival of mice on a high-calorie diet | Q27860950 | ||
| Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae. | Q27931333 | ||
| Sir2 blocks extreme life-span extension. | Q27931453 | ||
| Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites | Q27931488 | ||
| Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae | Q27931680 | ||
| Microarray deacetylation maps determine genome-wide functions for yeast histone deacetylases | Q27931861 | ||
| H4 acetylation does not replace H3 acetylation in chromatin remodelling and transcription activation of Adr1-dependent genes. | Q27932530 | ||
| The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases | Q27934108 | ||
| Nuclear export modulates the cytoplasmic Sir2 homologue Hst2. | Q27934693 | ||
| Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair. | Q27935926 | ||
| Acetylation in histone H3 globular domain regulates gene expression in yeast. | Q27937002 | ||
| Bromodomains mediate an acetyl-histone encoded antisilencing function at heterochromatin boundaries | Q27937031 | ||
| Genetic and epigenetic regulation of the FLO gene family generates cell-surface variation in yeast | Q27937126 | ||
| The sirtuins hst3 and Hst4p preserve genome integrity by controlling histone h3 lysine 56 deacetylation. | Q27937957 | ||
| A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast | Q27939446 | ||
| Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair | Q27940284 | ||
| Histone acetylation in chromatin structure and transcription | Q28131749 | ||
| Role of histone H3 lysine 27 methylation in Polycomb-group silencing | Q28131795 | ||
| Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans | Q28131824 | ||
| Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins | Q28139564 | ||
| Histone acetylation and an epigenetic code | Q28143767 | ||
| Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene | Q28205723 | ||
| Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1 | Q28237795 | ||
| Histone H4 acetylation in human cells. Frequency of acetylation at different sites defined by immunolabeling with site-specific antibodies | Q28238472 | ||
| Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer | Q28239595 | ||
| Mammalian SIRT1 represses forkhead transcription factors | Q28246430 | ||
| The Sir2 family of protein deacetylases | Q28266179 | ||
| Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients | Q28282424 | ||
| Genomic instability and aging-like phenotype in the absence of mammalian SIRT6 | Q28509079 | ||
| Methyl deficiency, alterations in global histone modifications, and carcinogenesis | Q28566748 | ||
| SIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation | Q28589415 | ||
| The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing | Q28594882 | ||
| Histone acetyltransferases | Q29547823 | ||
| Histone H4-K16 acetylation controls chromatin structure and protein interactions | Q29614521 | ||
| Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast | Q29614857 | ||
| Acetylation: a regulatory modification to rival phosphorylation? | Q29614886 | ||
| Histone methyltransferase activity of a Drosophila Polycomb group repressor complex | Q29615394 | ||
| Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites | Q29615395 | ||
| An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing | Q29617054 | ||
| Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction | Q29617574 | ||
| Extrachromosomal rDNA circles--a cause of aging in yeast | Q29618308 | ||
| Transcriptional silencing in yeast is associated with reduced nucleosome acetylation | Q29618497 | ||
| Hypomethylation distinguishes genes of some human cancers from their normal counterparts | Q29619217 | ||
| SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes | Q29619456 | ||
| Genetic analysis of histone H4: essential role of lysines subject to reversible acetylation | Q30452217 | ||
| Histone H4 and the maintenance of genome integrity | Q30464369 | ||
| Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine | Q30876890 | ||
| The interaction of Alba, a conserved archaeal chromatin protein, with Sir2 and its regulation by acetylation | Q31047769 | ||
| Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation | Q33238940 | ||
| Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae | Q33748056 | ||
| Diverse and dynamic functions of the Sir silencing complex | Q33764672 | ||
| UV irradiation stimulates histone acetylation and chromatin remodeling at a repressed yeast locus | Q33853904 | ||
| The Sir proteins of Saccharomyces cerevisiae: mediators of transcriptional silencing and much more. | Q33879831 | ||
| mof, a putative acetyl transferase gene related to the Tip60 and MOZ human genes and to the SAS genes of yeast, is required for dosage compensation in Drosophila | Q33886451 | ||
| Methylation of histone H4 by arginine methyltransferase PRMT1 is essential in vivo for many subsequent histone modifications | Q33917698 | ||
| Calorie restriction, SIRT1 and metabolism: understanding longevity | Q36071224 | ||
| The key to development: interpreting the histone code? | Q36083253 | ||
| Calorie restriction and SIR2 genes--towards a mechanism | Q36154774 | ||
| Acetylation of yeast histone H4 lysine 16: a switch for protein interactions in heterochromatin and euchromatin | Q36238564 | ||
| Genome-wide analysis of HDAC function | Q36253947 | ||
| Histone modifications: signalling receptors and potential elements of a heritable epigenetic code | Q36406933 | ||
| Chromatin assembly: a basic recipe with various flavours | Q36407748 | ||
| Deposition-related sites K5/K12 in histone H4 are not required for nucleosome deposition in yeast | Q36485781 | ||
| The biochemistry of sirtuins. | Q36498332 | ||
| Sirtuins in aging and age-related disease. | Q36549075 | ||
| Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern | Q36561489 | ||
| Long-range histone acetylation: biological significance, structural implications, and mechanisms | Q36579368 | ||
| Genome-wide dynamics of Htz1, a histone H2A variant that poises repressed/basal promoters for activation through histone loss | Q37458741 | ||
| Yeast chromatin assembly complex 1 protein excludes nonacetylatable forms of histone H4 from chromatin and the nucleus | Q37622511 | ||
| Yeast histone H4 and H3 N-termini have different effects on the chromatin structure of the GAL1 promoter. | Q37695775 | ||
| SIR2 modifies histone H4-K16 acetylation and affects superhelicity in the ARS region of plasmid chromatin in Saccharomyces cerevisiae. | Q39117291 | ||
| A critical epitope for substrate recognition by the nucleosome remodeling ATPase ISWI. | Q39530698 | ||
| Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nuclei | Q41116253 | ||
| Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress | Q42811705 | ||
| Selective use of H4 acetylation sites in the yeast Saccharomyces cerevisiae | Q42811712 | ||
| Point mutations in the yeast histone H4 gene prevent silencing of the silent mating type locus HML. | Q43183937 | ||
| SAS-mediated acetylation of histone H4 Lys 16 is required for H2A.Z incorporation at subtelomeric regions in Saccharomyces cerevisiae | Q43259704 | ||
| Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin | Q43430561 | ||
| Cell cycle and checkpoint regulation of histone H3 K56 acetylation by Hst3 and Hst4. | Q43796805 | ||
| Acetylation of the yeast histone H4 N terminus regulates its binding to heterochromatin protein SIR3. | Q43803659 | ||
| Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatin | Q44179355 | ||
| Chromosomal gradient of histone acetylation established by Sas2p and Sir2p functions as a shield against gene silencing | Q44200809 | ||
| Mass spectrometric quantification of acetylation at specific lysines within the amino-terminal tail of histone H4 | Q44403078 | ||
| Sir2 regulates histone H3 lysine 9 methylation and heterochromatin assembly in fission yeast | Q44515864 | ||
| Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry | Q44537505 | ||
| Centromere silencing and function in fission yeast is governed by the amino terminus of histone H3. | Q44619061 | ||
| Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly | Q44633411 | ||
| Mapping global histone acetylation patterns to gene expression | Q44928696 | ||
| Yeast histone H4 N-terminal sequence is required for promoter activation in vivo | Q45268200 | ||
| Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation | Q46501543 | ||
| Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice | Q46649057 | ||
| Drosophila Sir2 is required for heterochromatic silencing and by euchromatic Hairy/E(Spl) bHLH repressors in segmentation and sex determination | Q47070171 | ||
| SIR2 is required for polycomb silencing and is associated with an E(Z) histone methyltransferase complex | Q47071631 | ||
| CobB, a new member of the SIR2 family of eucaryotic regulatory proteins, is required to compensate for the lack of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase activity in cobT mutants during cobalamin biosynthesis i | Q48007137 | ||
| Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast. | Q48422925 | ||
| Histone H4 acetylated at lysine 16 and proteins of the Drosophila dosage compensation pathway co-localize on the male X chromosome through mitosis. | Q52541948 | ||
| Histone acetyltransferase complexes stabilize swi/snf binding to promoter nucleosomes. | Q52542735 | ||
| Modifications of H3 and H4 during chromatin replication, nucleosome assembly, and histone exchange. | Q55041606 | ||
| P433 | issue | 37 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 5505-5520 | |
| P577 | publication date | 2007-08-01 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs | |
| P478 | volume | 26 |
| Q35058520 | A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development |
| Q39823750 | A continuous microplate assay for sirtuins and nicotinamide-producing enzymes |
| Q36779668 | A nitric oxide-dependent cross-talk between class I and III histone deacetylases accelerates skin repair |
| Q29615367 | ATP-citrate lyase links cellular metabolism to histone acetylation |
| Q41377115 | Acetylation of hMOF Modulates H4K16ac to Regulate DNA Repair Genes in Response to Oxidative Stress. |
| Q35034763 | Activation of GSK3β by Sirt2 is required for early lineage commitment of mouse embryonic stem cell |
| Q38722716 | An HP1 isoform-specific feedback mechanism regulates Suv39h1 activity under stress conditions. |
| Q37392556 | Autophagy maintains ubiquitination-proteasomal degradation of Sirt3 to limit oxidative stress in K562 leukemia cells |
| Q40033702 | Beyond heterochromatin: SIR2 inhibits the initiation of DNA replication |
| Q37000927 | Bivalent domains enforce transcriptional memory of DNA methylated genes in cancer cells. |
| Q33732734 | Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function |
| Q58749838 | CRISPR-based reagents to study the influence of the epigenome on gene expression |
| Q24652611 | Calorie restriction and the exercise of chromatin |
| Q35947877 | Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation |
| Q48659470 | Changes in histone H4 acetylation during in vivo versus in vitro maturation of equine oocytes. |
| Q37866556 | Chromatin in the nuclear landscape. |
| Q28080683 | Constitutive heterochromatin formation and transcription in mammals |
| Q57289148 | Controversial Impact of Sirtuins in Chronic Non-Transmissible Diseases and Rehabilitation Medicine |
| Q38178832 | Cracking the survival code: autophagy-related histone modifications |
| Q37512907 | Cytotoxicity mediated by histone deacetylase inhibitors in cancer cells: mechanisms and potential clinical implications |
| Q34559675 | DNA methyltransferase 3b preferentially associates with condensed chromatin |
| Q36367732 | Deacetylation of H4-K16Ac and heterochromatin assembly in senescence |
| Q34610571 | Design and synthesis of novel hybrid benzamide-peptide histone deacetylase inhibitors |
| Q46240451 | Determination of protein lysine deacetylation |
| Q37220505 | Differential DNA lesion formation and repair in heterochromatin and euchromatin |
| Q34660121 | Discovery and characterization of protein-modifying natural products by MALDI mass spectrometry reveal potent SIRT1 and p300 inhibitors |
| Q50948674 | Disruption of Sirt1 in chondrocytes causes accelerated progression of osteoarthritis under mechanical stress and during ageing in mice. |
| Q34831586 | Distinct roles of the Gcn5 histone acetyltransferase revealed during transient stress-induced reprogramming of the genome |
| Q24314812 | Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promoters |
| Q34460981 | Epigenetic control of aging |
| Q37448564 | Epigenetic mechanisms facilitating oligodendrocyte development, maturation, and aging |
| Q36286662 | Epigenetic mechanisms in commonly occurring cancers. |
| Q29619753 | Epigenetic modifications and human disease |
| Q21245250 | Epigenetic regulation of caloric restriction in aging |
| Q34591910 | Epigenetics: A New Bridge between Nutrition and Health |
| Q37918376 | Epigenetics: new questions on the response to hypoxia |
| Q35910252 | Finding a balance: how diverse dosage compensation strategies modify histone h4 to regulate transcription |
| Q26741433 | From Genetics to Epigenetics: New Perspectives in Tourette Syndrome Research |
| Q60951267 | GRK5 - A Functional Bridge Between Cardiovascular and Neurodegenerative Disorders |
| Q33987657 | Genome-wide integration on transcription factors, histone acetylation and gene expression reveals genes co-regulated by histone modification patterns. |
| Q47879278 | Glioma-induced SIRT1-dependent activation of hMOF histone H4 lysine 16 acetyltransferase in microglia promotes a tumor supporting phenotype |
| Q27320850 | Group IVA Cytosolic Phospholipase A2 Regulates the G2-to-M Transition by Modulating the Activity of Tumor Suppressor SIRT2. |
| Q28240437 | HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention |
| Q37098834 | HDAC1 and HDAC2 in mouse oocytes and preimplantation embryos: Specificity versus compensation |
| Q34039987 | HDAC4: mechanism of regulation and biological functions |
| Q37347292 | High Glucose Induces Reactivation of Latent Kaposi's Sarcoma-Associated Herpesvirus |
| Q36833441 | High-resolution mapping of H4K16 and H3K23 acetylation reveals conserved and unique distribution patterns in Arabidopsis and rice |
| Q37398618 | Histone acetylation: truth of consequences? |
| Q28506706 | Histone deacetylase 2 (HDAC2) regulates chromosome segregation and kinetochore function via H4K16 deacetylation during oocyte maturation in mouse |
| Q34382527 | Histone deacetylase inhibitors: the epigenetic therapeutics that repress hypoxia-inducible factors |
| Q37705706 | Histone modifications as regulators of life and death in Saccharomyces cerevisiae |
| Q42153124 | Histone modifications in senescence-associated resistance to apoptosis by oxidative stress |
| Q38691865 | Histone modifying enzymes: novel disease biomarkers and assay development |
| Q24306345 | Human PIH1 associates with histone H4 to mediate the glucose-dependent enhancement of pre-rRNA synthesis |
| Q33405194 | Identification of a novel pathway that selectively modulates apoptosis of breast cancer cells |
| Q33870679 | Identifying Human SIRT1 Substrates by Integrating Heterogeneous Information from Various Sources. |
| Q37097951 | Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice |
| Q37083992 | Inclusion-body myositis: muscle-fiber molecular pathology and possible pathogenic significance of its similarity to Alzheimer's and Parkinson's disease brains |
| Q48907996 | Increased age is associated with epigenetic and structural changes in chromatin from neuronal nuclei. |
| Q28077579 | Integrating Epigenomics into the Understanding of Biomedical Insight |
| Q55480930 | Intraperitoneal injection of the SIRT1 activator SRT1720 attenuates the progression of experimental osteoarthritis in mice. |
| Q35835100 | Ionizing radiation induces immediate protein acetylation changes in human cardiac microvascular endothelial cells |
| Q36613033 | It's Time for An Epigenomics Roadmap of Heart Failure |
| Q34525541 | Low SIRT3 expression correlates with poor differentiation and unfavorable prognosis in primary hepatocellular carcinoma |
| Q33781123 | Lung cancer: a modified epigenome |
| Q56960691 | Lysine benzoylation is a histone mark regulated by SIRT2 |
| Q33963853 | MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair |
| Q38086003 | Macro domains as metabolite sensors on chromatin. |
| Q37707218 | Methamphetamine downregulates striatal glutamate receptors via diverse epigenetic mechanisms. |
| Q28553412 | Minnelide/Triptolide Impairs Mitochondrial Function by Regulating SIRT3 in P53-Dependent Manner in Non-Small Cell Lung Cancer |
| Q28396663 | Mitochondrial function in hypoxic ischemic injury and influence of aging |
| Q37736324 | Modern trends in lipomodeling |
| Q36484135 | Modifying metabolically sensitive histone marks by inhibiting glutamine metabolism affects gene expression and alters cancer cell phenotype |
| Q90862536 | Molecular basis for hierarchical histone de-β-hydroxybutyrylation by SIRT3 |
| Q33609107 | Mutations that Allow SIR2 Orthologs to Function in a NAD+-Depleted Environment. |
| Q100490695 | NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential |
| Q61796965 | NADP is an endogenous PARP inhibitor in DNA damage response and tumor suppression |
| Q92603993 | NMNAT2-mediated NAD+ generation is essential for quality control of aged oocytes |
| Q34540621 | Nuclear and chromatin reorganization during cell senescence and aging - a mini-review |
| Q43448263 | Nuclear expression of histone deacetylases and their histone modifications predicts clinical outcome in colorectal cancer. |
| Q37952442 | Nutritional influences on epigenetics and age-related disease |
| Q39745658 | Opposing effects of hMOF and SIRT1 on H4K16 acetylation and the sensitivity to the topoisomerase II inhibitor etoposide. |
| Q33857250 | Pharmacological manipulations of CNS sirtuins: potential effects on metabolic homeostasis. |
| Q36796895 | Quantitative dynamics of the link between cellular metabolism and histone acetylation. |
| Q40905859 | Redirection of Epithelial Immune Responses by Short-Chain Fatty Acids through Inhibition of Histone Deacetylases |
| Q57174409 | Revisiting the Advances in Isolation, Characterization and Secretome of Adipose-Derived Stromal/Stem Cells |
| Q46276226 | Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress |
| Q64084615 | Role of Natural Products in Modulating Histone Deacetylases in Cancer |
| Q59798260 | Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes |
| Q91792253 | Role of autophagy and histone deacetylases in diabetic nephropathy: Current status and future perspectives |
| Q37828315 | Role of histone deacetylases in vascular cell homeostasis and arteriosclerosis |
| Q37162737 | SIRT1 Mediates Depression-Like Behaviors in the Nucleus Accumbens. |
| Q34982578 | SIRT1 expression is associated with a poor prognosis, whereas DBC1 is associated with favorable outcomes in gastric cancer |
| Q39348163 | SIRT1 negatively regulates the activities, functions, and protein levels of hMOF and TIP60 |
| Q87359702 | SIRT1 promoter polymorphisms as clinical modifiers on systemic lupus erythematosus |
| Q35092686 | SIRT1-FOXO3a regulate cocaine actions in the nucleus accumbens |
| Q44572962 | SIRT1-dependent modulation of methylation and acetylation of histone H3 on lysine 9 (H3K9) in the zygotic pronuclei improves porcine embryo development |
| Q91678658 | SIRT1/2 orchestrate acquisition of DNA methylation and loss of histone H3 activating marks to prevent premature activation of inflammatory genes in macrophages |
| Q37150526 | SIRT1: Regulator of p53 Deacetylation |
| Q28482270 | SIRT2 ablation has no effect on tubulin acetylation in brain, cholesterol biosynthesis or the progression of Huntington's disease phenotypes in vivo |
| Q42029987 | SIRT2 is a tumor suppressor that connects aging, acetylome, cell cycle signaling, and carcinogenesis. |
| Q36435193 | SIRT3 functions in the nucleus in the control of stress-related gene expression |
| Q38936741 | Seeding for sirtuins: microseed matrix seeding to obtain crystals of human Sirt3 and Sirt2 suitable for soaking |
| Q30316777 | Selective Sirt2 inhibition by ligand-induced rearrangement of the active site. |
| Q37713905 | Short-chain fatty acids from periodontal pathogens suppress histone deacetylases, EZH2, and SUV39H1 to promote Kaposi's sarcoma-associated herpesvirus replication |
| Q37929090 | Signaling epigenetics: novel insights on cell signaling and epigenetic regulation |
| Q42021686 | Silenced yeast chromatin is maintained by Sir2 in preference to permitting histone acetylations for efficient NER. |
| Q37231714 | SirT1 regulation of antioxidant genes is dependent on the formation of a FoxO3a/PGC-1α complex |
| Q37956584 | Sirtuin 1 (SIRT1): the misunderstood HDAC. |
| Q26828607 | Sirtuin 1 and sirtuin 3: physiological modulators of metabolism |
| Q34068359 | Sirtuin 1 regulation of developmental genes during differentiation of stem cells. |
| Q37333750 | Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site |
| Q36379286 | Sirtuin regulation in aging and injury |
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