| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1021/CR000661E |
| P698 | PubMed publication ID | 11942792 |
| P50 | author | Pavel Martásek | Q42546185 |
| P2093 | author name string | Linda J Roman | |
| Bettie Sue Siler Masters | |||
| P2860 | cites work | Regulation of endothelium-derived nitric oxide production by the protein kinase Akt | Q22010149 |
| Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation | Q22010150 | ||
| P433 | issue | 4 | |
| P304 | page(s) | 1179-1190 | |
| P577 | publication date | 2002-04-01 | |
| P1433 | published in | Chemical Reviews | Q900502 |
| P1476 | title | Intrinsic and extrinsic modulation of nitric oxide synthase activity | |
| P478 | volume | 102 |
| Q28577114 | A conserved aspartate (Asp-1393) regulates NADPH reduction of neuronal nitric-oxide synthase: implications for catalysis |
| Q34159837 | A conserved flavin-shielding residue regulates NO synthase electron transfer and nicotinamide coenzyme specificity |
| Q88642251 | A docked state conformational dynamics model to explain the ionic strength dependence of FMN - heme electron transfer in nitric oxide synthase |
| Q37338939 | A professional and personal odyssey |
| Q44592824 | A tetrahydrobiopterin radical forms and then becomes reduced during Nomega-hydroxyarginine oxidation by nitric-oxide synthase |
| Q47842585 | Activation of peroxynitrite by inducible nitric-oxide synthase: a direct source of nitrative stress. |
| Q36148071 | Arabidopsis CaM1 and CaM4 Promote Nitric Oxide Production and Salt Resistance by Inhibiting S-Nitrosoglutathione Reductase via Direct Binding |
| Q42026462 | Binding kinetics of calmodulin with target peptides of three nitric oxide synthase isozymes |
| Q40727257 | Binding of PDZ domains to the carboxy terminus of inducible nitric oxide synthase boosts electron transfer and NO synthesis. |
| Q44044700 | Calmodulin activates electron transfer through neuronal nitric-oxide synthase reductase domain by releasing an NADPH-dependent conformational lock |
| Q44476772 | Characterization of Drosophila nitric oxide synthase: a biochemical study. |
| Q47934524 | Chimeric Enzymes of Cytochrome P450 Oxidoreductase and Neuronal Nitric-oxide Synthase Reductase Domain Reveal Structural and Functional Differences |
| Q64079643 | Colonic Transit Disorder Mediated by Downregulation of Interstitial Cells of Cajal/Anoctamin-1 in Dextran Sodium Sulfate-induced Colitis Mice |
| Q34111866 | Comparing the temperature dependence of FMN to heme electron transfer in full length and truncated inducible nitric oxide synthase proteins |
| Q79934219 | Computational modeling of factors that modulate the unique FeNO bonding in {FeNO}(6) heme-thiolate model complexes |
| Q42672439 | Conformation-dependent hydride transfer in neuronal nitric oxide synthase reductase domain |
| Q35001796 | Cysteine-mediated redox signaling: chemistry, biology, and tools for discovery |
| Q36962909 | Cytokines and lipopolysaccharides induce inducible nitric oxide synthase but not enzyme activity in adult rat cardiomyocytes |
| Q43249894 | Deletion of the autoregulatory insert modulates intraprotein electron transfer in rat neuronal nitric oxide synthase. |
| Q35865533 | Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair. |
| Q30914542 | Development of urea and thiourea kynurenamine derivatives: synthesis, molecular modeling, and biological evaluation as nitric oxide synthase inhibitors |
| Q36744200 | Differences in a conformational equilibrium distinguish catalysis by the endothelial and neuronal nitric-oxide synthase flavoproteins. |
| Q37498495 | Differential calmodulin-modulatory and electron transfer properties of neuronal nitric oxide synthase mu compared to the alpha variant. |
| Q37147032 | Discovery of highly potent and selective inhibitors of neuronal nitric oxide synthase by fragment hopping. |
| Q37350981 | Dissecting regulation mechanism of the FMN to heme interdomain electron transfer in nitric oxide synthases. |
| Q42162235 | Dissociation and unfolding of inducible nitric oxide synthase oxygenase domain identifies structural role of tetrahydrobiopterin in modulating the heme environment |
| Q42477248 | Distinct roles of nitric oxide synthases and interstitial cells of Cajal in rectoanal relaxation |
| Q38064332 | Dynamic control of electron transfers in diflavin reductases. |
| Q33976082 | Effect of solution viscosity on intraprotein electron transfer between the FMN and heme domains in inducible nitric oxide synthase |
| Q42222829 | Electron paramagnetic resonance characterization of tetrahydrobiopterin radical formation in bacterial nitric oxide synthase compared to mammalian nitric oxide synthase |
| Q57217155 | Electron transfer by neuronal nitric-oxide synthase is regulated by concerted interaction of calmodulin and two intrinsic regulatory elements |
| Q33702908 | Electron transfer in a human inducible nitric oxide synthase oxygenase/FMN construct co-expressed with the N-terminal globular domain of calmodulin |
| Q44368327 | Electron transfer is activated by calmodulin in the flavin domain of human neuronal nitric oxide synthase |
| Q30278654 | Endothelial nitric oxide synthase in the microcirculation |
| Q57181195 | Escorting α-globin to eNOS: α-globin-stabilizing protein paves the way |
| Q27665170 | Exploration of the Active Site of Neuronal Nitric Oxide Synthase by the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine Derivatives |
| Q34307636 | Holoenzyme structures of endothelial nitric oxide synthase - an allosteric role for calmodulin in pivoting the FMN domain for electron transfer |
| Q36471209 | How to control NO production in cells: N(omega),N(omega)-dimethyl-L-arginine dimethylaminohydrolase as a novel drug target |
| Q36403178 | Insight into structural rearrangements and interdomain interactions related to electron transfer between flavin mononucleotide and heme in nitric oxide synthase: A molecular dynamics study |
| Q37188160 | Intra- and inter-molecular effects of a conserved arginine residue of neuronal and inducible nitric oxide synthases on FMN and calmodulin binding. |
| Q34001998 | Intraprotein electron transfer between the FMN and heme domains in endothelial nitric oxide synthase holoenzyme. |
| Q33373365 | Intraprotein electron transfer in inducible nitric oxide synthase holoenzyme |
| Q33661383 | Lys842 in neuronal nitric-oxide synthase enables the autoinhibitory insert to antagonize calmodulin binding, increase FMN shielding, and suppress interflavin electron transfer |
| Q34241528 | Mechanism of Nitric Oxide Synthase Regulation: Electron Transfer and Interdomain Interactions. |
| Q44460134 | Mechanistic studies on the intramolecular one-electron transfer between the two flavins in the human neuronal nitric-oxide synthase and inducible nitric-oxide synthase flavin domains |
| Q36870964 | Metabolism of aminoguanidine, diaminoguanidine, and NG-amino-L-arginine by neuronal NO-synthase and covalent alteration of the heme prosthetic group |
| Q46917548 | Metallothionein-3 and neuronal nitric oxide synthase levels in brains from the Tg2576 mouse model of Alzheimer's disease |
| Q36812605 | Molecular mechanism of phase I and phase II drug-metabolizing enzymes: implications for detoxification |
| Q33237078 | Multiple lineage specific expansions within the guanylyl cyclase gene family |
| Q35126893 | Mutation in the flavin mononucleotide domain modulates magnetic circular dichroism spectra of the iNOS ferric cyano complex in a substrate-specific manner. |
| Q37368047 | Mutations in the FMN domain modulate MCD spectra of the heme site in the oxygenase domain of inducible nitric oxide synthase |
| Q30537968 | NADPH-cytochrome P450 oxidoreductase: prototypic member of the diflavin reductase family |
| Q26745553 | Neuronal Nitric Oxide Synthase in Vascular Physiology and Diseases |
| Q47727115 | Neuronal Rho GTPase Rac1 elimination confers neuroprotection in a mouse model of permanent ischemic stroke. |
| Q34449706 | Nitric oxide synthases activation and inhibition by metallacarborane-cluster-based isoform-specific affectors |
| Q37887771 | Nitric oxide: a guardian for vascular grafts? |
| Q40352723 | Nitric-oxide synthase output state. Design and properties of nitric-oxide synthase oxygenase/FMN domain constructs |
| Q37845397 | Novel nitric oxide synthase inhibitors: a patent review |
| Q28198119 | Origins of highly mosaic mycobacteriophage genomes |
| Q28833591 | Oxygen activation in NO synthases: evidence for a direct role of the substrate |
| Q54448333 | Oxygen metabolism by neuronal nitric-oxide synthase. |
| Q33700502 | Parallel evolution of nitric oxide signaling: diversity of synthesis and memory pathways. |
| Q35216227 | Pulsed ENDOR determination of relative orientation of g-frame and molecular frame of imidazole-coordinated heme center of iNOS |
| Q36067239 | Pulsed ENDOR determination of the arginine location in the ferrous-NO form of neuronal NOS. |
| Q33652757 | Pulsed EPR determination of the distance between heme iron and FMN centers in a human inducible nitric oxide synthase. |
| Q34104248 | Pulsed electron paramagnetic resonance study of domain docking in neuronal nitric oxide synthase: the calmodulin and output state perspective |
| Q34115975 | Recruitment of governing elements for electron transfer in the nitric oxide synthase family |
| Q40615821 | Redox properties of human endothelial nitric-oxide synthase oxygenase and reductase domains purified from yeast expression system |
| Q33923728 | Regulation of FMN subdomain interactions and function in neuronal nitric oxide synthase |
| Q44599542 | Regulation of Geometry around the Ruthenium Center of Bis(2-pyridinecarboxylato) Complexes by the Nitrosyl Moiety: Syntheses, Structures, and Theoretical Studies |
| Q33494841 | Regulation of interdomain electron transfer in the NOS output state for NO production |
| Q37431868 | Regulation of interdomain interactions by calmodulin in inducible nitric-oxide synthase |
| Q34660741 | Regulatory role of Glu546 in flavin mononucleotide-heme electron transfer in human inducible nitric oxide synthase. |
| Q33926497 | Role of a Conserved Tyrosine Residue in the FMN-Heme Interdomain Electron Transfer in Inducible Nitric Oxide Synthase. |
| Q36479661 | Role of an isoform-specific serine residue in FMN-heme electron transfer in inducible nitric oxide synthase |
| Q33767490 | Role of an isoform-specific substrate access channel residue in CO ligand accessibilities of neuronal and inducible nitric oxide synthase isoforms. |
| Q39762460 | Role of arginine guanidinium moiety in nitric-oxide synthase mechanism of oxygen activation. |
| Q35811770 | Solving Kinetic Equations for the Laser Flash Photolysis Experiment on Nitric Oxide Synthases: Effect of Conformational Dynamics on the Interdomain Electron Transfer |
| Q33830350 | Structural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain |
| Q44945441 | Structural basis for isozyme-specific regulation of electron transfer in nitric-oxide synthase. |
| Q27644394 | Structure-Based Design and Synthesis of N ω -Nitro- l -Arginine-Containing Peptidomimetics as Selective Inhibitors of Neuronal Nitric Oxide Synthase. Displacement of the Heme Structural Water |
| Q33779913 | Tetrahydrobiopterin, superoxide, and vascular dysfunction |
| Q35087935 | The generation of free radicals by nitric oxide synthase |
| Q57217019 | The role of a conserved serine residue within hydrogen bonding distance of FAD in redox properties and the modulation of catalysis by Ca2+/calmodulin of constitutive nitric-oxide synthases |
| Q45126647 | Thermodynamic and kinetic analysis of the nitrosyl, carbonyl, and dioxy heme complexes of neuronal nitric-oxide synthase. The roles of substrate and tetrahydrobiopterin in oxygen activation |
| Q38285800 | Towards the free energy landscape for catalysis in mammalian nitric oxide synthases. |
| Q27660323 | Unexpected Binding Modes of Nitric Oxide Synthase Inhibitors Effective in the Prevention of a Cerebral Palsy Phenotype in an Animal Model |
| Q48703857 | Vascular reactivity and endothelial NOS activity in rat thoracic aorta during and after hyperbaric oxygen exposure. |
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