DDX3 DEAD-box RNA helicase is a host factor that restricts hepatitis B virus replication at the transcriptional level

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DDX3 DEAD-box RNA helicase is a host factor that restricts hepatitis B virus replication at the transcriptional level is …
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scholarly articleQ13442814

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P356DOI10.1128/JVI.02035-14
P932PMC publication ID4248967
P698PubMed publication ID25231298
P5875ResearchGate publication ID265792051

P50authorWang-Shick RyuQ54417426
P2093author name stringMarc P Windisch
Sooyoung Lee
Chunkyu Ko
P2860cites workSodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virusQ21128797
Hepatitis C virus core protein interacts with a human DEAD box protein DDX3Q22010035
Hepatitis B virus polymerase blocks pattern recognition receptor signaling via interaction with DDX3: implications for immune evasionQ24293039
DDX3 DEAD-box RNA helicase is required for hepatitis C virus RNA replicationQ24293603
DDX3, a DEAD box RNA helicase with tumor growth-suppressive property and transcriptional regulation activity of the p21waf1/cip1 promoter, is a candidate tumor suppressorQ24295660
Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activationQ24315019
Cellular cofactors affecting hepatitis C virus infection and replicationQ24317564
The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune responseQ24336273
The enigmatic X gene of hepatitis B virusQ24561887
The restriction factors of human immunodeficiency virusQ24605108
Characterization of the intracellular deproteinized relaxed circular DNA of hepatitis B virus: an intermediate of covalently closed circular DNA formationQ24681546
Requirement of DDX3 DEAD box RNA helicase for HIV-1 Rev-RRE export functionQ28289911
The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twenty-something years onQ28296342
The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeysQ29547689
Epidemiology of viral hepatitis and hepatocellular carcinomaQ29617918
DEAD-box proteins: the driving forces behind RNA metabolismQ29619863
Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases in vitro and in vivoQ33852042
Inhibition of hepatitis B virus replication by MyD88 involves accelerated degradation of pregenomic RNA and nuclear retention of pre-S/S RNAsQ33990530
Production of hepatitis B virus particles in Hep G2 cells transfected with cloned hepatitis B virus DNA.Q34596607
Hepatitis B virus DNA is subject to extensive editing by the human deaminase APOBEC3C.Q34649306
Inhibition of hepatitis B virus replication by the host zinc finger antiviral proteinQ34819738
Formation of hepatitis B virus covalently closed circular DNA: removal of genome-linked proteinQ35857166
Deamination-independent inhibition of hepatitis B virus reverse transcription by APOBEC3G.Q35857453
In vitro epsilon RNA-dependent protein priming activity of human hepatitis B virus polymerase.Q35943827
Human DEAD box helicase 3 couples IκB kinase ε to interferon regulatory factor 3 activation.Q36826843
The DEAD-box helicase DDX3 substitutes for the cap-binding protein eIF4E to promote compartmentalized translation initiation of the HIV-1 genomic RNAQ36963199
Activation of pattern recognition receptor-mediated innate immunity inhibits the replication of hepatitis B virus in human hepatocyte-derived cellsQ37033361
Interleukin-1 and tumor necrosis factor-α trigger restriction of hepatitis B virus infection via a cytidine deaminase activation-induced cytidine deaminase (AID)Q37272140
Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function.Q37418293
Residues Arg703, Asp777, and Arg781 of the RNase H domain of hepatitis B virus polymerase are critical for viral DNA synthesis.Q37547715
Control of cccDNA function in hepatitis B virus infection.Q37555389
Human DEAD-box protein 3 has multiple functions in gene regulation and cell cycle control and is a prime target for viral manipulationQ37603777
The DEAD box proteins DDX5 (p68) and DDX17 (p72): multi-tasking transcriptional regulatorsQ38092526
Hepatitis B and D viruses exploit sodium taurocholate co-transporting polypeptide for species-specific entry into hepatocytes.Q38310253
Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA.Q39021951
Cellular DDX3 regulates Japanese encephalitis virus replication by interacting with viral un-translated regionsQ39034822
Cyclosporin A inhibits hepatitis B and hepatitis D virus entry by cyclophilin-independent interference with the NTCP receptorQ39051196
A southern blot assay for detection of hepatitis B virus covalently closed circular DNA from cell culturesQ39131353
Identification of disubstituted sulfonamide compounds as specific inhibitors of hepatitis B virus covalently closed circular DNA formationQ39340555
Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKKepsiloQ39717470
DDX3 DEAD-Box RNA helicase inhibits hepatitis B virus reverse transcription by incorporation into nucleocapsids.Q39871089
Stimulation of hepatitis B virus genome replication by HBx is linked to both nuclear and cytoplasmic HBx expressionQ39876689
Oncogenic role of DDX3 in breast cancer biogenesis.Q40014680
Hepatitis B virus polymerase suppresses translation of pregenomic RNA via a mechanism involving its interaction with 5' stem-loop structureQ40031776
Interferon-inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replicationQ40275011
Inhibition of hepatitis B virus replication by APOBEC3G.Q40576734
APOBEC-mediated interference with hepadnavirus productionQ46605399
P433issue23
P407language of work or nameEnglishQ1860
P921main subjectHepatitis B virusQ6844
hepatitis BQ6853
P304page(s)13689-13698
P577publication date2014-09-17
P1433published inJournal of VirologyQ1251128
P1476titleDDX3 DEAD-box RNA helicase is a host factor that restricts hepatitis B virus replication at the transcriptional level
P478volume88

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cites work (P2860)
Q40409391Analyses of HBV cccDNA Quantification and Modification.
Q28068209Cell Culture Models for the Investigation of Hepatitis B and D Virus Infection
Q37347289DDB1 Stimulates Viral Transcription of Hepatitis B Virus via HBx-Independent Mechanisms
Q89598976DEAD-Box Helicases: Sensors, Regulators, and Effectors for Antiviral Defense
Q89896482DEAD-box RNA Helicase DDX3: Functional Properties and Development of DDX3 Inhibitors as Antiviral and Anticancer Drugs
Q40213813Discrimination of Self and Non-Self Ribonucleic Acids
Q91993592Effects of Moloney Leukemia Virus 10 Protein on Hepatitis B Virus Infection and Viral Replication
Q45323932Global micro RNA expression profiling in the liver biopsies of Hepatitis B Virus infected patients suggests specific miRNA signatures for viral persistence and hepatocellular injury
Q41112559Hepatitis B virus X protein enhances Myc stability by inhibiting SCF(Skp2) ubiquitin E3 ligase-mediated Myc ubiquitination and contributes to oncogenesis
Q47157641Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques
Q92767464Hypoxia-induced human deoxyribonuclease I is a cellular restriction factor of hepatitis B virus
Q36343335Interferon-inducible ribonuclease ISG20 inhibits hepatitis B virus replication through directly binding to the epsilon stem-loop structure of viral RNA
Q37374825Intracellular detection of viral nucleic acids.
Q93079831Mapping the Interactions of HBV cccDNA with Host Factors
Q26749143Multifunctional DDX3: dual roles in various cancer development and its related signaling pathways
Q38299880Multiple functions of DDX3 RNA helicase in gene regulation, tumorigenesis, and viral infection
Q90646295Parvulin 14 and Parvulin 17 Bind to HBx and cccDNA and Upregulate Hepatitis B Virus Replication from cccDNA to Virion in an HBx-Dependent Manner
Q38547052RNA helicase DDX3: at the crossroad of viral replication and antiviral immunity.
Q49894793Role of HBx in hepatitis B virus persistence and its therapeutic implications
Q59354475Sirtuin 2 Isoform 1 Enhances Hepatitis B Virus RNA Transcription and DNA Synthesis via the AKT/GSK-3β/β-Catenin Signaling Pathway
Q89551149Suppression of Hepatocyte Nuclear Factor 4 α by Long-term Infection of Hepatitis B Virus Contributes to Tumor Cell Proliferation
Q38718442The ATP-Dependent RNA Helicase DDX3X Modulates Herpes Simplex Virus 1 Gene Expression.
Q41586218The role of Moloney leukemia virus 10 in hepatitis B virus expression in hepatoma cells

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