| P50 | author | Martin S. Tallman | Q69035242 |
| | Elisabeth Paietta | Q69071275 |
| P2093 | author name string | David B Rosen | |
| | Alessandra Cesano | |
| | Santosh Putta | |
| | Rachael E Hawtin | |
| | Zhuoxin Sun | |
| | Urte Gayko | |
| | Aileen C Cohen | |
| | John Woronicz | |
| | Kavita Mathi | |
| | Larry Cripe | |
| P2860 | cites work | Hallmarks of Cancer: The Next Generation | Q22252312 |
| | Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a cancer and leukemia group B study. | Q27824774 |
| | Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype | Q27824827 |
| | Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML). | Q27824861 |
| | The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia | Q27851416 |
| | Favorable prognostic impact of NPM1 mutations in older patients with cytogenetically normal de novo acute myeloid leukemia and associated gene- and microRNA-expression signatures: a Cancer and Leukemia Group B study | Q27851545 |
| | Prognostic impact of FLT3-ITD load in NPM1 mutated acute myeloid leukemia | Q27851642 |
| | Acute myeloid leukemia: 2012 update on diagnosis, risk stratification, and management | Q27851694 |
| | Prognostic relevance of integrated genetic profiling in acute myeloid leukemia | Q27851726 |
| | Flt3 signaling involves tyrosyl-phosphorylation of SHP-2 and SHIP and their association with Grb2 and Shc in Baf3/Flt3 cells | Q28138943 |
| | Substrate specificities and identification of a putative binding site for PI3K in the carboxy tail of the murine Flt3 receptor tyrosine kinase | Q28507072 |
| | Distinct patterns of DNA damage response and apoptosis correlate with Jak/Stat and PI3kinase response profiles in human acute myelogenous leukemia | Q28749564 |
| | FLT3 as a therapeutic target in AML: still challenging after all these years | Q29042570 |
| | Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells | Q29616552 |
| | Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric acute myeloid leukemia | Q31774863 |
| | Functional characterization of FLT3 receptor signaling deregulation in acute myeloid leukemia by single cell network profiling (SCNP). | Q33737486 |
| | Cells expressing FLT3/ITD mutations exhibit elevated repair errors generated through alternative NHEJ pathways: implications for genomic instability and therapy | Q34450478 |
| | The predictive value of hierarchical cytogenetic classification in older adults with acute myeloid leukemia (AML): analysis of 1065 patients entered into the United Kingdom Medical Research Council AML11 trial | Q34517235 |
| | The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the Unite | Q34517403 |
| | Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis | Q34523534 |
| | A phase 3 study of three induction regimens and of priming with GM-CSF in older adults with acute myeloid leukemia: a trial by the Eastern Cooperative Oncology Group | Q34542232 |
| | No evidence that FLT3 status should be considered as an indicator for transplantation in acute myeloid leukemia (AML): an analysis of 1135 patients, excluding acute promyelocytic leukemia, from the UK MRC AML10 and 12 trials. | Q34559865 |
| | Signal transducer and activator of transcription proteins in leukemias. | Q35024969 |
| | Dynamic single-cell network profiles in acute myelogenous leukemia are associated with patient response to standard induction therapy | Q36065836 |
| | Signal transduction of oncogenic Flt3. | Q36251180 |
| | Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling | Q36368800 |
| | Functional pathway analysis in acute myeloid leukemia using single cell network profiling assay: effect of specimen source (bone marrow or peripheral blood) on assay readouts | Q36784704 |
| | STAT5 signaling in normal and pathologic hematopoiesis | Q36813606 |
| | Mitogenic Signalling and Substrate Specificity of the Flk2/Flt3 Receptor Tyrosine Kinase in Fibroblasts and Interleukin 3-Dependent Hematopoietic Cells | Q36824500 |
| | Hematopoietic cytokine receptor signaling | Q36970188 |
| | Deregulation of signaling pathways in acute myeloid leukemia | Q37240553 |
| | Internal tandem duplication of FLT3 (FLT3/ITD) induces increased ROS production, DNA damage, and misrepair: implications for poor prognosis in AML. | Q40025562 |
| | Toward quantitative fluorescence measurements with multicolor flow cytometry | Q40138316 |
| | A standardized ZAP-70 assay--lessons learned in the trenches | Q40244012 |
| | FLT3 signaling in hematopoietic cells involves CBL, SHC and an unknown P115 as prominent tyrosine-phosphorylated substrates | Q41053168 |
| | c-kit ligand and Flt3 ligand: stem/progenitor cell factors with overlapping yet distinct activities | Q41695888 |
| | Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: a study of the AML Study Group Ulm. | Q44189526 |
| | Human Flt3 is expressed at the hematopoietic stem cell and the granulocyte/macrophage progenitor stages to maintain cell survival | Q46587239 |
| | Pediatric AML primary samples with FLT3/ITD mutations are preferentially killed by FLT3 inhibition | Q47422865 |
| | FLT3 mutation and response to intensive chemotherapy in young adult and elderly patients with normal karyotype | Q47665617 |
| | Multi-platform, multi-site instrumentation and reagent standardization. | Q53351169 |
| | Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways. | Q53403767 |
| | Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations. | Q54613492 |
| | Prognostic value of internal tandem duplication of the FLT3 gene in childhood acute myelogenous leukemia | Q73208706 |
| | Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines | Q73501441 |
| | Phosphatase and tensin homologue phosphorylation in the C-terminal regulatory domain is frequently observed in acute myeloid leukaemia and associated with poor clinical outcome | Q73701961 |
| | Internal tandem duplication of the FLT3 gene and clinical evaluation in childhood acute myeloid leukemia. The Children's Cancer and Leukemia Study Group, Japan | Q74524088 |
| | Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia | Q77363619 |
| | Constitutive activity of signal transducer and activator of transcription 3 protein in acute myeloid leukemia blasts is associated with short disease-free survival | Q77387079 |
| | Tyrosine kinases as targets for cancer therapy | Q80367757 |
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | pathway analysis | Q25303877 |
| P304 | page(s) | e56714 | |
| P577 | publication date | 2013-02-19 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Functional pathway analysis using SCNP of FLT3 receptor pathway deregulation in AML provides prognostic information independent from mutational status | |
| P478 | volume | 8 | |