review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Claes Gustafsson | Q55300680 |
P2093 | author name string | Jeremy Minshull | |
Alan Villalobos | |||
Mark Welch | |||
P2860 | cites work | Gene Designer: a synthetic biology tool for constructing artificial DNA segments | Q21284253 |
SimulFold: simultaneously inferring RNA structures including pseudoknots, alignments, and trees using a Bayesian MCMC framework | Q21563523 | ||
The codon Adaptation Index--a measure of directional synonymous codon usage bias, and its potential applications | Q24498207 | ||
Ribosome stalling and peptidyl-tRNA drop-off during translational delay at AGA codons | Q24562411 | ||
Comparison of correspondence analysis methods for synonymous codon usage in bacteria | Q24657604 | ||
Synthetic biology: new engineering rules for an emerging discipline | Q24672399 | ||
Comparative context analysis of codon pairs on an ORFeome scale | Q24797417 | ||
A simple model based on mutation and selection explains trends in codon and amino-acid usage and GC composition within and across genomes | Q24797873 | ||
Co-transcriptional folding is encoded within RNA genes | Q24803935 | ||
GeMS: an advanced software package for designing synthetic genes | Q24806471 | ||
What makes ribosome-mediated transcriptional attenuation sensitive to amino acid limitation? | Q24811430 | ||
JCat: a novel tool to adapt codon usage of a target gene to its potential expression host | Q24812232 | ||
Do universal codon-usage patterns minimize the effects of mutation and translation error? | Q24813693 | ||
tRNA properties help shape codon pair preferences in open reading frames | Q25256741 | ||
Evolutionary programming as a platform for in silico metabolic engineering | Q25257616 | ||
Optimization by Simulated Annealing | Q25939004 | ||
Environmental genome shotgun sequencing of the Sargasso Sea | Q27860605 | ||
Heterologous protein expression is enhanced by harmonizing the codon usage frequencies of the target gene with those of the expression host. | Q30369393 | ||
Directed evolution of a genetic circuit | Q30870894 | ||
Unexpected correlations between gene expression and codon usage bias from microarray data for the whole Escherichia coli K-12 genome | Q30884442 | ||
Codon bias at the 3'-side of the initiation codon is correlated with translation initiation efficiency in Escherichia coli | Q32062779 | ||
Near-critical behavior of aminoacyl-tRNA pools in E. coli at rate-limiting supply of amino acids | Q33208194 | ||
Expanding the metabolic engineering toolbox: more options to engineer cells | Q33270419 | ||
Sequence similarity is more relevant than species specificity in probabilistic backtranslation. | Q33274888 | ||
OptCircuit: an optimization based method for computational design of genetic circuits | Q33322237 | ||
Highly conserved regimes of neighbor-base-dependent mutation generated the background primary-structural heterogeneities along vertebrate chromosomes | Q33334428 | ||
Natural computation meta-heuristics for the in silico optimization of microbial strains | Q33387681 | ||
Recombinant protein expression in Escherichia coli | Q33744852 | ||
Secondary structure of the ribosome binding site determines translational efficiency: a quantitative analysis | Q33825350 | ||
Nonrandom utilization of codon pairs in Escherichia coli | Q33857615 | ||
Codon bias and heterologous protein expression | Q33979754 | ||
Metabolic efficiency and amino acid composition in the proteomes of Escherichia coli and Bacillus subtilis | Q34019786 | ||
Translation is a non-uniform process. Effect of tRNA availability on the rate of elongation of nascent polypeptide chains | Q34054633 | ||
Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes: A proposal for a synonymous codon choice that is optimal for the E. coli translational system | Q34054909 | ||
Codon usage in bacteria: correlation with gene expressivity | Q34056325 | ||
Effects of rare codon clusters on high-level expression of heterologous proteins in Escherichia coli | Q34058060 | ||
Synonymous codon bias is related to gene length in Escherichia coli: selection for translational accuracy? | Q34063045 | ||
Ribosome-mediated translational pause and protein domain organization | Q34063382 | ||
Selective charging of tRNA isoacceptors induced by amino-acid starvation | Q34166656 | ||
Gene expression and molecular evolution | Q34420781 | ||
Strategies for optimizing heterologous protein expression in Escherichia coli | Q34458728 | ||
Reconstruction of genetic circuits | Q34470075 | ||
Absolute protein expression profiling estimates the relative contributions of transcriptional and translational regulation. | Q34594316 | ||
Revisiting the codon adaptation index from a whole-genome perspective: analyzing the relationship between gene expression and codon occurrence in yeast using a variety of models | Q34966113 | ||
Influences of mRNA secondary structure on initiation by eukaryotic ribosomes | Q35602187 | ||
Correlation between mechanical strength of messenger RNA pseudoknots and ribosomal frameshifting | Q35719907 | ||
Mechanisms of elongation on the ribosome: dynamics of a macromolecular machine | Q35922844 | ||
Recognition and selection of tRNA in translation | Q36024296 | ||
Synthetic biology--putting engineering into biology | Q36586096 | ||
Control of translation by mRNA secondary structure in Escherichia coli. A quantitative analysis of literature data | Q36727373 | ||
Designing biological systems | Q36731984 | ||
Following translation by single ribosomes one codon at a time. | Q36915705 | ||
Engineering and applications of genetic circuits | Q37000368 | ||
Synonymous mutations and ribosome stalling can lead to altered folding pathways and distinct minima | Q37066299 | ||
Engineering prokaryotic gene circuits | Q37328414 | ||
mRNA helicase activity of the ribosome | Q38331986 | ||
Ribosomal pausing at a frameshifter RNA pseudoknot is sensitive to reading phase but shows little correlation with frameshift efficiency | Q39529314 | ||
Gratuitous overexpression of genes in Escherichia coli leads to growth inhibition and ribosome destruction | Q39836003 | ||
Effects of a minor isoleucyl tRNA on heterologous protein translation in Escherichia coli | Q39839470 | ||
A codon window in mRNA downstream of the initiation codon where NGG codons give strongly reduced gene expression in Escherichia coli | Q40157109 | ||
Codon usage bias from tRNA's point of view: redundancy, specialization, and efficient decoding for translation optimization | Q40299578 | ||
Reduced synonymous substitution rate at the start of enterobacterial genes | Q40415708 | ||
Codon catalog usage is a genome strategy modulated for gene expressivity | Q40495447 | ||
Suppression of the negative effect of minor arginine codons on gene expression; preferential usage of minor codons within the first 25 codons of the Escherichia coli genes | Q40515131 | ||
Codon usage and gene expression | Q40561153 | ||
Errors of heterologous protein expression | Q41238667 | ||
Synonymous substitution rates in enterobacteria. | Q41659361 | ||
Optimal encoding rules for synthetic genes: the need for a community effort | Q42560165 | ||
The effects of differential gene expression on coding sequence features: analysis by one-way ANOVA. | Q42621346 | ||
Frameshift events associated with the lysyl-tRNA and the rare arginine codon, AGA, in Escherichia coli: a case study involving the human Relaxin 2 protein | Q42655130 | ||
Coevolution of codon usage and transfer RNA abundance | Q43851327 | ||
Influences on translation initiation and early elongation by the messenger RNA region flanking the initiation codon at the 3' side | Q44009176 | ||
Effects of codon usage versus putative 5'-mRNA structure on the expression of Fusarium solani cutinase in the Escherichia coli cytoplasm | Q44268096 | ||
Kinetic determinants of high-fidelity tRNA discrimination on the ribosome | Q44753572 | ||
Codon pair utilization biases influence translational elongation step times | Q46515085 | ||
Unfolding of mRNA secondary structure by the bacterial translation initiation complex | Q46838029 | ||
Genetdes: automatic design of transcriptional networks | Q48402161 | ||
Codon pairs in the genome of Escherichia coli. | Q50796273 | ||
Limitations of codon adaptation index and other coding DNA-based features for prediction of protein expression in Saccharomyces cerevisiae. | Q51986650 | ||
Codon contexts from weakly expressed genes reduce expression in vivo. | Q52244607 | ||
Eukaryotic expression: developments for structural proteomics. | Q52672667 | ||
Rates of aminoacyl-tRNA selection at 29 sense codons in vivo. | Q52867127 | ||
Codon contexts in enterobacterial and coliphage genes. | Q52869362 | ||
Co-variation of tRNA abundance and codon usage in Escherichia coli at different growth rates. | Q52888301 | ||
Selective charging of tRNA isoacceptors explains patterns of codon usage. | Q54523461 | ||
Effect of distribution of unfavourable codons on the maximum rate of gene expression by an heterologous organism. | Q54780371 | ||
Sense codons are found in specific contexts. | Q54798749 | ||
Codon optimization can improve expression of human genes in Escherichia coli: A multi-gene study. | Q55048769 | ||
Role of the AGA/AGG codons, the rarest codons in global gene expression in Escherichia coli | Q72801102 | ||
Construct for high-level expression and low misincorporation of lysine for arginine during expression of pET-encoded eukaryotic proteins in Escherichia coli | Q73206776 | ||
Cooperative effects by the initiation codon and its flanking regions on translation initiation | Q74608439 | ||
Mutation-selection models of codon substitution and their use to estimate selective strengths on codon usage | Q80454136 | ||
Abortive translation caused by peptidyl-tRNA drop-off at NGG codons in the early coding region of mRNA | Q81339352 | ||
P304 | page(s) | S467-76 | |
P577 | publication date | 2009-03-11 | |
P1433 | published in | Journal of the Royal Society Interface | Q2492390 |
P1476 | title | You're one in a googol: optimizing genes for protein expression | |
P478 | volume | 6 Suppl 4 |
Q40267694 | A comparative analysis on the synonymous codon usage pattern in viral functional genes and their translational initiation region of ASFV. |
Q34042157 | A critical analysis of codon optimization in human therapeutics |
Q30390766 | All-codon scanning identifies p53 cancer rescue mutations |
Q50511278 | Application of targeted proteomics to metabolically engineered Escherichia coli. |
Q48096076 | Biochemical mechanisms determine the functional compatibility of heterologous genes. |
Q38298550 | Bringing functions together with fusion enzymes--from nature's inventions to biotechnological applications |
Q38636510 | Clinical potential of electroporation for gene therapy and DNA vaccine delivery |
Q36692751 | Codon Bias as a Means to Fine-Tune Gene Expression |
Q42108750 | Codon optimization and factorial screening for enhanced soluble expression of human ciliary neurotrophic factor in Escherichia coli |
Q35675656 | Codon-Optimized NADH Oxidase Gene Expression and Gene Fusion with Glycerol Dehydrogenase for Bienzyme System with Cofactor Regeneration |
Q34668314 | Comparison of two codon optimization strategies to enhance recombinant protein production in Escherichia coli. |
Q28659192 | Design and analysis of LacI-repressed promoters and DNA-looping in a cyanobacterium |
Q21090049 | Design parameters to control synthetic gene expression in Escherichia coli |
Q34293596 | Drug resistance is conferred on the model yeast Saccharomyces cerevisiae by expression of full-length melanoma-associated human ATP-binding cassette transporter ABCB5. |
Q34198748 | Engineering genes for predictable protein expression |
Q30010028 | Engineering of an elastic scaffolding polyprotein based on an SH3-binding intrinsically disordered titin PEVK module |
Q44938609 | Enhanced production of Aspergillus niger laccase-like multicopper oxidases through mRNA optimization of the glucoamylase expression system |
Q33957241 | Gene Assembly from Chip-Synthesized Oligonucleotides. |
Q36250704 | Gene design, fusion technology and TEV cleavage conditions influence the purification of oxidized disulphide-rich venom peptides in Escherichia coli. |
Q37654831 | Genetic code redundancy and its influence on the encoded polypeptides |
Q34016175 | Genome-scale analysis of translation elongation with a ribosome flow model |
Q50905525 | Improved production of membrane proteins in Escherichia coli by selective codon substitutions. |
Q41136863 | Improving heterologous membrane protein production in Escherichia coli by combining transcriptional tuning and codon usage algorithms. |
Q36326228 | Incorporation of a tag helps to overcome expression variability in a recombinant host |
Q37925161 | Manipulating the genetic code for membrane protein production: what have we learnt so far? |
Q38075856 | Metabolic reconstruction and flux analysis of industrial Pichia yeasts. |
Q31043307 | Multi-omics data driven analysis establishes reference codon biases for synthetic gene design in microbial and mammalian cells |
Q42399631 | Multifactorial Determinants of Protein Expression in Prokaryotic Open Reading Frames |
Q52723035 | New Vaccine Formulations Containing a Modified Version of the Amastigote 2 Antigen and the Non-Virulent Trypanosoma cruzi CL-14 Strain Are Highly Antigenic and Protective against Leishmania infantum Challenge. |
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Q51549378 | Parallel on-chip gene synthesis and application to optimization of protein expression. |
Q42287635 | Potential roles of synonymous codon usage and tRNA concentration in hosts on the two initiation regions of foot-and-mouth disease virus RNA. |
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Q51750916 | Predicting the expression of recombinant monoclonal antibodies in Chinese hamster ovary cells based on sequence features of the CDR3 domain. |
Q34635129 | Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin |
Q39762292 | Proline availability regulates proline-4-hydroxylase synthesis and substrate uptake in proline-hydroxylating recombinant Escherichia coli. |
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Q33824070 | Selecting an appropriate method for expressing S locus F-box-S2 recombinant protein |
Q39189210 | Stable In Vivo Transgene Expression in Endothelial Cells with Helper-Dependent Adenovirus: Roles of Promoter and Interleukin-10. |
Q36327788 | Stable plastid transformation for high-level recombinant protein expression: promises and challenges. |
Q50880151 | Strategies and Considerations for Improving Expression of "Difficult to Express" Proteins in CHO Cells. |
Q34151543 | Synonymous but not the same: the causes and consequences of codon bias |
Q42860873 | Synthetic biology: history, challenges and prospects |
Q38951951 | Synthetic gene design-The rationale for codon optimization and implications for molecular pharming in plants. |
Q49490467 | The Road from Host-Defense Peptides to a New Generation of Antimicrobial Drugs |
Q33605059 | The challenges of informatics in synthetic biology: from biomolecular networks to artificial organisms |
Q24498611 | The distribution of synonymous codon choice in the translation initiation region of dengue virus |
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Q28658494 | Tipping points in seaweed genetic engineering: scaling up opportunities in the next decade |
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Q36128982 | Transgene expression in the striatum following intracerebral injections of DNA nanoparticles encoding for human glial cell line-derived neurotrophic factor |
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