scholarly article | Q13442814 |
P356 | DOI | 10.1172/JCI111304 |
P8608 | Fatcat ID | release_4yswatulpjdrhicazl4nftxzze |
P932 | PMC publication ID | 425132 |
P698 | PubMed publication ID | 6423666 |
P5875 | ResearchGate publication ID | 16771970 |
P50 | author | Clifton Bogardus | Q64495509 |
P2093 | author name string | Stone K | |
Lillioja S | |||
Mott D | |||
P2860 | cites work | Characteristics of the dephosphoryated form of phosphorylase purified from rat liver and measurement of its activity in crude liver preparations | Q30110880 |
Effect of muscle glycogen depletion on in vivo insulin action in man. | Q36992248 | ||
Mechanisms of insulin resistance in human obesity: evidence for receptor and postreceptor defects | Q37023008 | ||
Glycogen synthase: a new activity ratio assay expressing a high sensitivity to the phosphorylation state | Q39693824 | ||
The effect of chronic sulfonylurea therapy on hepatic glucose production in non-insulin-dependent diabetes. | Q51651477 | ||
The glycogen synthase system in skeletal muscle of normal humans and patients with myotonic dystrophy: effect of glucose and insulin administration. | Q51675953 | ||
Oral glucose effect on glycogen synthetase and phosphorylase in heart. Muscle and liver | Q68366897 | ||
Dose-response characteristics for effects of insulin on production and utilization of glucose in man | Q70157794 | ||
The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization | Q70196543 | ||
Radioactive method for the assay of glycogen phosphorylases | Q70386813 | ||
Insulin secretion, insulin resistance, and obesity | Q71439402 | ||
Splanchnic and peripheral disposal of oral glucose in man | Q71763755 | ||
Lysis of131I-Labelled Plasma Clots in Human Subcutaneous Tissue in Vivo | Q72234978 | ||
Impaired Glycogen Synthase Activating System in Human Diabetic Polymorphonuclear Leukocytes | Q72853048 | ||
Biosynthesis of glycogen from uridine diphosphate glucose | Q78586523 | ||
Influences of glucose loading and of injected insulin on hepatic glucose output | Q79273897 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | preproinsulin | Q7240673 |
P304 | page(s) | 1185-1190 | |
P577 | publication date | 1984-04-01 | |
P1433 | published in | Journal of Clinical Investigation | Q3186904 |
P1476 | title | Correlation between muscle glycogen synthase activity and in vivo insulin action in man. | |
P478 | volume | 73 |
Q43552091 | 3-Anilino-4-arylmaleimides: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3). |
Q35600062 | 31P nuclear magnetic resonance measurements of muscle glucose-6-phosphate. Evidence for reduced insulin-dependent muscle glucose transport or phosphorylation activity in non-insulin-dependent diabetes mellitus |
Q44406427 | 5-aryl-pyrazolo[3,4-b]pyridazines: potent inhibitors of glycogen synthase kinase-3 (GSK-3). |
Q73281007 | 5-aryl-pyrazolo[3,4-b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3) |
Q44563620 | 6-aryl-pyrazolo[3,4-b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3). |
Q44563623 | 6-heteroaryl-pyrazolo[3,4-b]pyridines: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3). |
Q35820212 | Activation of skeletal muscle casein kinase II by insulin is not diminished in subjects with insulin resistance |
Q42511444 | Adipocyte glycogen synthase and pyruvate dehydrogenase in obese and type II diabetic subjects |
Q37139419 | Age-related impairments in skeletal muscle PDH phosphorylation and plasma lactate are indicative of metabolic inflexibility and the effects of exercise training |
Q40572109 | Alterations in carbohydrate metabolism during stress: a review of the literature |
Q35711899 | Alterations of glucose metabolism in type 2 diabetes mellitus. An overview |
Q33657201 | Amylin found in amyloid deposits in human type 2 diabetes mellitus may be a hormone that regulates glycogen metabolism in skeletal muscle |
Q42520400 | Association of the glycogen synthase locus on 19q13 with NIDDM in Pima Indians |
Q40812896 | Cellular insulin action and insulin resistance |
Q29619549 | Cellular mechanisms of insulin resistance |
Q51587403 | Central adiposity and its metabolic correlates in obese adolescent girls. |
Q33889791 | Characterization of cellular defects of insulin action in type 2 (non-insulin-dependent) diabetes mellitus |
Q51562539 | Comparison of effects of captopril used either alone or in combination with a thiazide diuretic on insulin action in hypertensive Type 2 diabetic patients: a double-blind crossover study. |
Q40511503 | Correction of chronic hyperglycemia with vanadate, but not with phlorizin, normalizes in vivo glycogen repletion and in vitro glycogen synthase activity in diabetic skeletal muscle |
Q39557893 | Correlation of in vivo and in vitro actions of insulin in obesity and noninsulin-dependent diabetes mellitus: role of the glucose transport system |
Q41019246 | Decreased insulin activation of glycogen synthase in skeletal muscles in young nonobese Caucasian first-degree relatives of patients with non-insulin-dependent diabetes mellitus |
Q34556125 | Decreased kinase activity of insulin receptors from adipocytes of non-insulin-dependent diabetic subjects |
Q34237915 | Defective insulin response of cyclic adenosine monophosphate-dependent protein kinase in insulin-resistant humans |
Q35598096 | Defective insulin response of phosphorylase phosphatase in insulin-resistant humans |
Q34208049 | Deficiency in phosphorylase phosphatase activity despite elevated protein phosphatase type-1 catalytic subunit in skeletal muscle from insulin-resistant subjects |
Q43638657 | Determinants of insulin-stimulated glucose disposal in middle-aged, premenopausal women |
Q38765264 | Differential methylation of genes in individuals exposed to maternal diabetes in utero |
Q37351139 | Direct assessment of liver glycogen storage by 13C nuclear magnetic resonance spectroscopy and regulation of glucose homeostasis after a mixed meal in normal subjects. |
Q44230857 | Direct assessment of muscle glycogen storage after mixed meals in normal and type 2 diabetic subjects |
Q33861927 | Direct observation of glycogen synthesis in human muscle with 13C NMR |
Q38679703 | Does insulin resistance primarily affect skeletal muscle? |
Q37257333 | Dual regulation of muscle glycogen synthase during exercise by activation and compartmentalization. |
Q40342372 | Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with non-insulin-dependent diabetes mellitus |
Q34251702 | Effects of acute hyperglycemia on myocardial glycolytic activity in humans |
Q35762624 | Effects of fat on glucose uptake and utilization in patients with non-insulin-dependent diabetes |
Q54272719 | Effects of glucose and insulin on development of impaired insulin action in muscle |
Q69503001 | Effects of growth hormone on insulin sensitivity and forearm metabolism in normal man |
Q35578164 | Effects of insulin infusion on human skeletal muscle pyruvate dehydrogenase, phosphofructokinase, and glycogen synthase. Evidence for their role in oxidative and nonoxidative glucose metabolism |
Q44053861 | Effects of obesity on substrate utilization during exercise |
Q39489343 | Effects of physiological hyperinsulinemia on the intracellular metabolic partition of plasma glucose |
Q53561556 | Effects of three different conjugated linoleic acid preparations on insulin signalling, fat oxidation and mitochondrial function in rats fed a high-fat diet. |
Q68228321 | Evidence that glucose transport is rate-limiting for in vivo glucose uptake |
Q34556312 | Evidence that insulin resistance is responsible for the decreased thermic effect of glucose in human obesity |
Q54325244 | Evolution of dexamethasone-induced insulin resistance in rats. |
Q35893366 | Exercise with calorie restriction improves insulin sensitivity and glycogen synthase activity in obese postmenopausal women with impaired glucose tolerance |
Q41233806 | Expression of the gene encoding glycogen phosphorylase is elevated in diabetic rat skeletal muscle and is regulated by insulin and cyclic AMP. |
Q43545210 | Flux control in the rat gastrocnemius glycogen synthesis pathway by in vivo 13C/31P NMR spectroscopy |
Q24317664 | Genetic analysis of human type 1 protein phosphatase inhibitor 2 in insulin-resistant Pima Indians |
Q40553849 | Genetic epidemiology of non-insulin-dependent diabetes. |
Q40812879 | Genetics of insulin action |
Q57817319 | Glucose infusion causes insulin resistance in skeletal muscle of rats without changes in Akt and AS160 phosphorylation |
Q71061277 | Glucose processing during the intravenous glucose tolerance test |
Q37359438 | Glycogen synthase activity is reduced in cultured skeletal muscle cells of non-insulin-dependent diabetes mellitus subjects. Biochemical and molecular mechanisms |
Q42130807 | Hibiscus rosa sinensis Linn. Petals Modulates Glycogen Metabolism and Glucose Homeostasis Signalling Pathway in Streptozotocin-Induced Experimental Diabetes |
Q72795603 | How to measure insulin action in vivo |
Q37361512 | Human primary myoblast cell cultures from non-diabetic insulin resistant subjects retain defects in insulin action |
Q24309360 | Human rsk isoforms: cloning and characterization of tissue-specific expression |
Q28319139 | Hyperglycaemia compensates for the defects in insulin-mediated glucose metabolism and in the activation of glycogen synthase in the skeletal muscle of patients with type 2 (non-insulin-dependent) diabetes mellitus |
Q35817890 | Hyperglycemia normalizes insulin-stimulated skeletal muscle glucose oxidation and storage in noninsulin-dependent diabetes mellitus |
Q44180582 | Hyperglycemia reduces nitric oxide synthase and glycogen synthase activity in endothelial cells |
Q36628044 | Impaired glucose metabolism and exercise capacity with muscle-specific glycogen synthase 1 (gys1) deletion in adult mice |
Q35592495 | Impaired insulin-stimulated muscle glycogen synthase activation in vivo in man is related to low fasting glycogen synthase phosphatase activity |
Q46210543 | Importance of transcapillary insulin transport to dynamics of insulin action after intravenous glucose |
Q33907975 | In vivo regulation of muscle glycogen synthase and the control of glycogen synthesis |
Q71949310 | Increased concentrations of glycogen synthase protein in skeletal muscle of patients with NIDDM |
Q42517148 | Increased nonoxidative glucose metabolism in idiopathic reactive hypoglycemia |
Q58172430 | Inhibition of muscle glycogen synthase activity and non-oxidative glucose disposal during hypoglycaemia in normal man |
Q54117527 | Insulin action and insulin resistance: diseases involving defects in insulin receptors, signal transduction, and the glucose transport effector system. |
Q48021605 | Insulin action in skeletal muscle from patients with NIDDM. |
Q40643524 | Insulin action, thermogenesis and obesity |
Q47889718 | Insulin decreases skeletal muscle cAMP-dependent protein kinase (PKA) activity in normal monkeys and increases PKA activity in insulin-resistant rhesus monkeys |
Q51577735 | Insulin regulates liver glycogen synthase and glycogen phosphorylase activity reciprocally in rhesus monkeys. |
Q37175187 | Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle |
Q35209149 | Insulin resistance in adipose tissue: direct and indirect effects of tumor necrosis factor-alpha |
Q33898062 | Insulin resistance in liver cirrhosis. Positron-emission tomography scan analysis of skeletal muscle glucose metabolism |
Q42472533 | Insulin resistance in normal rats infused with glucose for 72 h. |
Q38679694 | Insulin resistance in skeletal muscles of patients with diabetes mellitus |
Q34242862 | Insulin resistance is associated with reduced fasting and insulin-stimulated glycogen synthase phosphatase activity in human skeletal muscle |
Q54284041 | Insulin secretion, insulin sensitivity and glucose-mediated glucose disposal in Cushing's disease: a minimal model analysis |
Q42823635 | Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase |
Q44689779 | Insulin-sensitive tyrosine kinase: relationship with in vivo insulin action in humans |
Q34110324 | Interaction between glucose and free fatty acid metabolism in human skeletal muscle |
Q34243161 | Intracellular glucose oxidation and glycogen synthase activity are reduced in non-insulin-dependent (type II) diabetes independent of impaired glucose uptake |
Q34576085 | Kinetics of glucose disposal in whole body and across the forearm in man. |
Q95501469 | Loss of hnRNP A1 in murine skeletal muscle exacerbates high-fat diet-induced onset of insulin resistance and hepatic steatosis |
Q24562106 | Mechanism of free fatty acid-induced insulin resistance in humans |
Q51557248 | Mechanism of muscle glycogen autoregulation in humans. |
Q42609727 | Metabolic control analysis of insulin-stimulated glucose disposal in rat skeletal muscle. |
Q37420270 | Metabolic inflexibility during submaximal aerobic exercise is associated with glucose intolerance in obese older adults |
Q40814275 | Metabolic origin of insulin resistance in obesity with and without type 2 (non-insulin-dependent) diabetes mellitus |
Q34335931 | Molecular cloning and chromosomal localization of a human skeletal muscle PP-1 gamma 1 cDNA. |
Q44360239 | Mortality and morbidity in laboratory-maintained Rhesus monkeys and effects of long-term dietary restriction |
Q34236518 | Multiple defects in muscle glycogen synthase activity contribute to reduced glycogen synthesis in non-insulin dependent diabetes mellitus |
Q51632625 | Muscle enzyme activity and insulin sensitivity in type 1 (insulin-dependent) diabetes mellitus. |
Q54248309 | Muscle glucose uptake during and after exercise is normal in insulin-resistant rats. |
Q33283340 | Muscle mitochondrial ATP synthesis and glucose transport/phosphorylation in type 2 diabetes |
Q54515187 | New variants in the glycogen synthase gene (Gln71His, Met416Val) in patients with NIDDM from eastern Finland. |
Q72147658 | Noninvasive assessment of in vivo glycogen kinetics in humans: effect of increased physical activity on glycogen breakdown and synthesis |
Q51624905 | Oxidative and non-oxidative glucose metabolism in non-obese type 2 (non-insulin-dependent) diabetic patients. |
Q36499329 | Palmitate action to inhibit glycogen synthase and stimulate protein phosphatase 2A increases with risk factors for type 2 diabetes |
Q42492203 | Palmitate oxidation rate and action on glycogen synthase in myoblasts from insulin-resistant subjects |
Q54374951 | Pancreatic amylin and calcitonin gene-related peptide cause resistance to insulin in skeletal muscle in vitro. |
Q54049618 | Pathogenesis of non-insulin-dependent (type II) diabetes mellitus (NIDDM) - genetic predisposition and metabolic abnormalities. |
Q53872253 | Pathophysiology and long-term management of the metabolic syndrome. |
Q37382166 | Postabsorptive respiratory quotient and insulin-stimulated glucose storage rate in nondiabetic pima indians are related To glycogen synthase fractional activity in cultured myoblasts |
Q43545200 | Preoperative oral carbohydrate treatment attenuates immediate postoperative insulin resistance |
Q48021729 | Protein phosphatase-1 and insulin action |
Q52654104 | Rate-limiting steps for insulin-mediated glucose uptake into perfused rat hindlimb. |
Q74229008 | Re-evaluation of exercise prescription for Japanese type 2 diabetic patients by ventilatory threshold |
Q54299084 | Reduced glycogen synthase activity in skeletal muscle from obese patients with and without type 2 (non-insulin-dependent) diabetes mellitus. |
Q44058308 | Regulation of endogenous glucose production after a mixed meal in type 2 diabetes |
Q37384513 | Regulation of endogenous glucose production by glucose per se is impaired in type 2 diabetes mellitus |
Q35575530 | Regulation of glycogen synthase and phosphorylase activities by glucose and insulin in human skeletal muscle |
Q51571937 | Relationship of glycogen synthase and glycogen phosphorylase to protein phosphatase 2C and cAMP-dependent protein kinase in liver of obese rhesus monkeys. |
Q54215168 | Relationship of skeletal muscle glucose 6-phosphate to glucose disposal rate and glycogen synthase activity in insulin-resistant and non-insulin-dependent diabetic rhesus monkeys. |
Q34616729 | Relationships between insulin secretion, insulin action, and fasting plasma glucose concentration in nondiabetic and noninsulin-dependent diabetic subjects |
Q40347307 | Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake. A dose-response euglycemic clamp study in normal and diabetic rats |
Q35176134 | Resistance to Injection: 1991 RD Lawrence Lecture |
Q34212389 | Severe insulin-resistant diabetes mellitus in patients with congenital muscle fiber type disproportion myopathy |
Q42475436 | Skeletal muscle glycogen synthase subcellular localization: effects of insulin and PPAR-alpha agonist (K-111) administration in rhesus monkeys |
Q33910469 | Skeletal muscle glycogenolysis is more sensitive to insulin than is glucose transport/phosphorylation. Relation to the insulin-mediated inhibition of hepatic glucose production |
Q37624257 | Skeletal muscle insulin resistance is the primary defect in type 2 diabetes |
Q54002331 | Stimulation of muscle glucose disposal by insulin in humans is a function of the preexisting plasma insulin level. |
Q39842987 | Subcellular translocation of glucose transporters: role in insulin action and its perturbation in altered metabolic states. |
Q51611436 | The Effect of Sulphonylurea Therapy on Skeletal Muscle Glycogen Synthase Activity and Insulin Secretion in Newly Presenting Type 2 (Non-insulin-dependent) Diabetic Patients |
Q42513614 | The basal kinetic parameters of glycogen synthase in human myotube cultures are not affected by chronic high insulin exposure. |
Q54296039 | The effect of an amino acid beverage on glucose response and glycogen replenishment after strenuous exercise. |
Q34921325 | The evolution of insulin resistance in muscle of the glucose infused rat |
Q37953209 | The phospholipid/arachidonic acid second messenger system: its possible role in physiology and pathophysiology of metabolism |
Q41391462 | The relationship between insulin sensitivity and skeletal muscle enzyme activities in hepatic cirrhosis |
Q38038512 | The role of glycogen synthase in the development of hyperglycemia in type 2 diabetes: 'To store or not to store glucose, that's the question'. |
Q40926661 | Thermic effect of glucose in man. Obligatory and facultative thermogenesis |
Q34114343 | Transmembrane glucose transport in skeletal muscle of patients with non-insulin-dependent diabetes |
Q44680759 | Unlike insulin, amino acids stimulate p70S6K but not GSK-3 or glycogen synthase in human skeletal muscle |