The glycine transport inhibitor sarcosine is an inhibitory glycine receptor agonist

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The glycine transport inhibitor sarcosine is an inhibitory glycine receptor agonist is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.NEUROPHARM.2009.07.019
P932PMC publication ID2836904
P698PubMed publication ID19619564
P5875ResearchGate publication ID26683290

P2093author name stringHai Xia Zhang
Liu Lin Thio
Ariel Lyons-Warren
P2860cites workThe glycine transport inhibitor sarcosine is an NMDA receptor co-agonist that differs from glycine.Q46015939
Zinc enhances the inhibitory effects of strychnine-sensitive glycine receptors in mouse hippocampal neuronsQ46968688
Glycine uptake regulates hippocampal network activity via glycine receptor-mediated tonic inhibitionQ48157761
Nonketotic hyperglycinemia: treatment with diazepam--a competitor for glycine receptorsQ51854885
The taurine uptake inhibitor guanidinoethyl sulphonate is an agonist at γ-aminobutyric acidA receptors in cultured murine cerebellar granule cellsQ57944286
Functional comparisons of three glutamate transporter subtypes cloned from human motor cortexQ24306108
Sarcosine (N-methylglycine) treatment for acute schizophrenia: a randomized, double-blind studyQ28238182
Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to antipsychotics for the treatment of schizophreniaQ28250711
Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled studyQ28280894
Molecular cloning and tissue distribution of rat sarcosine dehydrogenaseQ28290567
Cloning and expression of a glycine transporter reveal colocalization with NMDA receptorsQ28565322
Glutamate and schizophrenia: beyond the dopamine hypothesisQ33996803
Pharmacological assessment of the role of the glycine transporter GlyT-1 in mediating high-affinity glycine uptake by rat cerebral cortex and cerebellum synaptosomesQ34516173
Pharmacology and expression analysis of glycine transporter GlyT1 with [3H]-(N-[3-(4'-fluorophenyl)-3-(4'phenylphenoxy)propyl])sarcosineQ34536543
Glycine transporters: essential regulators of neurotransmission.Q34558485
Glycine transport inhibitors for the treatment of schizophrenia: symptom and disease modificationQ34609422
Differential properties of two stably expressed brain-specific glycine transporters.Q34754615
Rare neurodevelopmental abnormalities of sarcosinemia may involve glycinergic stimulation of a primed N-methyl-d-aspartate receptorQ36649545
Potentiation of the NMDA receptor in the treatment of schizophrenia: focused on the glycine siteQ36954416
Quantitative profiling of folate and one-carbon metabolism in large-scale epidemiological studies by mass spectrometryQ36982670
Characterization of quisqualate receptor desensitization in cultured postnatal rat hippocampal neuronsQ41140318
Guanidinoethyl sulphonate is a glycine receptor antagonist in striatumQ41829239
Benzodiazepines block alpha2-containing inhibitory glycine receptors in embryonic mouse hippocampal neuronsQ44378949
Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levelsQ44830222
Differential presynaptic modulation of excitatory and inhibitory autaptic currents in cultured hippocampal neuronsQ44906521
Bergmann glial GlyT1 mediates glycine uptake and release in mouse cerebellar slicesQ45032627
P433issue5-6
P921main subjectsarcosineQ414157
P304page(s)551-555
P577publication date2009-07-18
P1433published inNeuropharmacologyQ15332439
P1476titleThe glycine transport inhibitor sarcosine is an inhibitory glycine receptor agonist
P478volume57

Reverse relations

cites work (P2860)
Q37673343Effects of sarcosine and N, N-dimethylglycine on NMDA receptor-mediated excitatory field potentials.
Q43052069Effects of sarcosine, a glycine transporter type 1 inhibitor, in two mouse seizure models
Q41230295Extracellular glycine is necessary for optimal hemoglobinization of erythroid cells
Q28290774Glutamate receptor ion channels: structure, regulation, and function
Q42953258Neuroprotection via Strychnine-Sensitive Glycine Receptors During Post-ischemic Recovery of Excitatory Synaptic Transmission in the Hippocampus
Q37583961ON or OFF?: Modulating the N-Methyl-D-Aspartate Receptor in Major Depression.
Q35158211Role of glycine receptors in glycine-induced LTD in hippocampal CA1 pyramidal neurons
Q42292999The Startle Disease Mutation E103K Impairs Activation of Human Homomeric α1 Glycine Receptors by Disrupting an Intersubunit Salt Bridge across the Agonist Binding Site
Q27316372The lidocaine metabolite N-ethylglycine has antinociceptive effects in experimental inflammatory and neuropathic pain.
Q37749515The specification of glycinergic neurons and the role of glycinergic transmission in development

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