Matrix metalloproteinases in cancer: prognostic markers and therapeutic targets.

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Matrix metalloproteinases in cancer: prognostic markers and therapeutic targets. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1002/IJC.10329
P698PubMed publication ID11979428
P5875ResearchGate publication ID11390814

P50authorPia VihinenQ57400959
P2093author name stringVeli-Matti Kähäri
P2860cites workCloning and characterization of human MMP-23, a new matrix metalloproteinase predominantly expressed in reproductive tissues and lacking conserved domains in other family membersQ22001456
Identification and characterization of a novel human matrix metalloproteinase with unique structural characteristics, chromosomal location, and tissue distributionQ24317893
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A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomasQ28116420
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Matrix metalloproteinasesQ28140451
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesisQ28140740
Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defenseQ28145389
Broad antitumor and antiangiogenic activities of AG3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trialsQ28369525
Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysinQ28589898
Matrix metalloproteinase degradation of extracellular matrix: biological consequencesQ28611041
Regulation of matrix metalloproteinase activity in ischemic tissue by interleukin-10: role in ischemia-induced angiogenesisQ30697267
Development of matrix metalloproteinase inhibitors in cancer therapy.Q31832006
Cytotoxic activity and inhibition of tumor cell invasion by derivatives of a chemically modified tetracycline CMT-3 (COL-3).Q31922966
Marimastat in recurrent colorectal cancer: exploratory evaluation of biological activity by measurement of carcinoembryonic antigenQ33177387
Expression and role of matrix metalloproteinases MMP-2 and MMP-9 in human spinal column tumors.Q33270666
Phase I and pharmacologic study of the specific matrix metalloproteinase inhibitor BAY 12-9566 on a protracted oral daily dosing schedule in patients with solid malignanciesQ33331110
Matrix metalloproteinases and their inhibitors in tumour growth and invasionQ33603385
Promising new developments in cancer chemotherapyQ33651996
Measurement of matrix metalloproteinases and tissue inhibitors of metalloproteinases in blood and tissues. Clinical and experimental applicationsQ33692926
Matrix metalloproteinases: biologic activity and clinical implicationsQ33849967
Matrix metalloproteinase inhibitors: applications in oncology.Q33888231
Matrix metalloproteinases: molecular aspects of their roles in tumour invasion and metastasisQ34013787
Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatmentQ34293595
Role of the matrix metalloproteinase and plasminogen activator-plasmin systems in angiogenesis.Q34307809
Matrix metalloproteinases regulate neovascularization by acting as pericellular fibrinolysinsQ34479986
Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomasQ34497741
Increased expression of collagenase-3 (MMP-13) and MT1-MMP in oesophageal cancer is related to cancer aggressivenessQ35360505
Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase IQ35669086
Collagenase-3 (MMP-13) is expressed by tumor cells in invasive vulvar squamous cell carcinomas.Q35745256
Expression levels of genes that regulate metastasis and angiogenesis correlate with advanced pathological stage of renal cell carcinomaQ35746324
Collagenase-3 (MMP-13) expression in chondrosarcoma cells and its regulation by basic fibroblast growth factorQ35753232
Tissue levels of matrix metalloproteinases MMP-2 and MMP-9 are related to the overall survival of patients with gastric carcinomaQ36135756
In vivo evidence that the stromelysin-3 metalloproteinase contributes in a paracrine manner to epithelial cell malignancyQ36255141
Imbalance between serum matrix metalloproteinase-2 and its inhibitor as a predictor of recurrence of urothelial cancerQ36291671
Expression of tissue inhibitor of metalloproteinases TIMP-2 in human colorectal cancer--a predictor of tumour stageQ36431093
Expression of collagenases-1 and -3 and their inhibitors TIMP-1 and -3 correlates with the level of invasion in malignant melanomasQ36617718
The clinical significance of MMP-1 expression in oesophageal carcinomaQ36622489
Upregulation and differential expression of matrilysin (MMP-7) and metalloelastase (MMP-12) and their inhibitors TIMP-1 and TIMP-3 in Barrett's oesophageal adenocarcinomaQ36623544
Prediction of colorectal cancer relapse and survival via tissue RNA levels of matrix metalloproteinase-9.Q36836819
Expression of metalloproteinases endometrial stromal sarcoma: immunohistochemical study using image analysisQ37230996
Phase I clinical trial of oral COL-3, a matrix metalloproteinase inhibitor, in patients with refractory metastatic cancerQ40608619
Ongoing trials with matrix metalloproteinase inhibitorsQ40740781
MMP inhibition and downregulation by bisphosphonates.Q40804689
Expression of human macrophage metalloelastase (MMP-12) by tumor cells in skin cancerQ40875227
Progelatinase A mRNA expression in cell lines derived from tumors in patients with metastatic renal cell carcinoma correlates inversely with survivalQ41097692
Role of matrix metalloproteinases in abdominal aortic aneurysmsQ41261468
Differential regulation of interstitial collagenase (MMP-1) gene expression by ETS transcription factorsQ42439334
Human collagenase-3 is expressed in malignant squamous epithelium of the skinQ42442111
Reversible sideroblastic anemia associated with the tetracycline analogue COL-3.Q43560616
Significance of matrix metalloproteinases and tissue inhibitors of metalloproteinase expression in the recurrence of superficial transitional cell carcinoma of the bladderQ43601092
Marimastat as first-line therapy for patients with unresectable pancreatic cancer: a randomized trialQ43693195
High expression levels of collagenase-1 and stromelysin-1 correlate with shorter disease-free survival in human metastatic melanomaQ43861059
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: clinicopathologic and prognostic significance of matrilysin expression.Q43912549
Matrix metalloproteinase-2 (MMP-2) immunoreactive protein--a new prognostic marker in uveal melanoma?Q44901177
Phase I trial of Marimastat, a novel matrix metalloproteinase inhibitor, administered orally to patients with advanced lung cancerQ47976225
Prognostic value of MMP-2 immunoreactive protein (72 kD type IV collagenase) in primary skin melanoma.Q50849840
Matrix metalloproteinase 2 immunoreactive protein appears early in cervical epithelial dedifferentiation.Q53425886
Expression and Prognostic Significance of Metalloproteinases and Their Tissue Inhibitors in Patients With Small-Cell Lung CancerQ57272687
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)157-166
P577publication date2002-05-01
P1433published inInternational Journal of CancerQ332492
P1476titleMatrix metalloproteinases in cancer: prognostic markers and therapeutic targets
P478volume99

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Q51742979The expression of CXCR4 and its relationship with matrix metalloproteinase-9/vascular endothelial growth factor in esophageal squamous cell cancer
Q24671121The guanylate binding protein-1 GTPase controls the invasive and angiogenic capability of endothelial cells through inhibition of MMP-1 expression
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