scholarly article | Q13442814 |
P2093 | author name string | Yehuda G Assaraf | |
Michal Stark | |||
Shachar Raz | |||
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Resistance to multiple novel antifolates is mediated via defective drug transport resulting from clustered mutations in the reduced folate carrier gene in human leukaemia cell lines | Q24534739 | ||
Transcription factor binding sites in the pol gene intragenic regulatory region of HIV-1 are important for virus infectivity | Q24815940 | ||
Folate-binding triggers the activation of folylpolyglutamate synthetase | Q27634058 | ||
UCSF Chimera--a visualization system for exploratory research and analysis | Q27860666 | ||
A direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein gene | Q28507391 | ||
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Regulation of human CYP2C9 expression by electrophilic stress involves activator protein 1 activation and DNA looping. | Q34024630 | ||
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Molecular basis for decreased folylpoly-gamma-glutamate synthetase expression in a methotrexate resistant CCRF-CEM mutant cell line | Q34652639 | ||
Differential Inhibition of the TGF-β Signaling Pathway in HCC Cells Using the Small Molecule Inhibitor LY2157299 and the D10 Monoclonal Antibody against TGF-β Receptor Type II. | Q34796473 | ||
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Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate | Q37351011 | ||
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Antifolates in cancer therapy: structure, activity and mechanisms of drug resistance | Q38037835 | ||
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Loss of folylpoly-gamma-glutamate synthetase activity is a dominant mechanism of resistance to polyglutamylation-dependent novel antifolates in multiple human leukemia sublines. | Q38359462 | ||
Targeted expression of human folylpolyglutamate synthase for selective enhancement of methotrexate chemotherapy in osteosarcoma cells | Q39109782 | ||
Down-regulation and CpG island hypermethylation of CRYAA in age-related nuclear cataract | Q39298160 | ||
BRG1 helps RNA polymerase II to overcome a nucleosomal barrier during elongation, in vivo | Q39657381 | ||
Smad signaling is required to maintain epigenetic silencing during breast cancer progression. | Q39750283 | ||
Histone deacetylase inhibitors induce FPGS mRNA expression and intracellular accumulation of long-chain methotrexate polyglutamates in childhood acute lymphoblastic leukemia: implications for combination therapy | Q39752287 | ||
Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts at diagnosis of childhood acute lymphoblastic leukemia: a pilot prognostic factor analysis | Q41762709 | ||
Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport. | Q42824941 | ||
Aberrant splicing of folylpolyglutamate synthetase as a novel mechanism of antifolate resistance in leukemia. | Q46170702 | ||
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The coding sequence mediates induction of 5-lipoxygenase expression by Smads3/4 | Q80139696 | ||
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P433 | issue | 19 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | leukemia | Q29496 |
P304 | page(s) | 9183-9198 | |
P577 | publication date | 2014-10-01 | |
P1433 | published in | Oncotarget | Q1573155 |
P1476 | title | Binding of a Smad4/Ets-1 complex to a novel intragenic regulatory element in exon12 of FPGS underlies decreased gene expression and antifolate resistance in leukemia | |
P478 | volume | 5 |
Q38821227 | Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance |
Q39206549 | Identification of mutations, gene expression changes and fusion transcripts by whole transcriptome RNAseq in docetaxel resistant prostate cancer cells |
Q90266353 | Single-Cell Transcriptomics Reveals Spatial and Temporal Turnover of Keratinocyte Differentiation Regulators |
Q42728890 | miR-144-3p, a tumor suppressive microRNA targeting ETS-1 in laryngeal squamous cell carcinoma |
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